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Volumn 29, Issue 8, 2015, Pages 1013-1026

Dementia of the eye: The role of amyloid beta in retinal degeneration

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN ANTIBODY;

EID: 84939199775     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2015.100     Document Type: Article
Times cited : (132)

References (104)
  • 2
    • 84865751901 scopus 로고    scopus 로고
    • Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXBFKBPL-NOTCH4 region of chromosome 6p21.3
    • Cipriani V, LeungHT, Plagnol V, Bunce C, Khan JC, ShahidH et al. Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXBFKBPL-NOTCH4 region of chromosome 6p21.3. Hum Mol Genet 2012; 21(18): 4138-4150.
    • (2012) Hum Mol Genet , vol.21 , Issue.18 , pp. 4138-4150
    • Cipriani, V.1    Leung, H.T.2    Plagnol, V.3    Bunce, C.4    Khan, J.C.5    Shahid, H.6
  • 4
    • 45449086898 scopus 로고    scopus 로고
    • Progress in understanding and treating agerelated macular degeneration
    • Lotery A. Progress in understanding and treating agerelated macular degeneration. Eye (Lond) 2008; 22(6): 739-741.
    • (2008) Eye (Lond) , vol.22 , Issue.6 , pp. 739-741
    • Lotery, A.1
  • 5
    • 35448975681 scopus 로고    scopus 로고
    • Progress in defining the molecular biology of age related macular degeneration
    • Lotery A, Trump D. Progress in defining the molecular biology of age related macular degeneration. Hum Genet 2007; 122(3-4): 219-236.
    • (2007) Hum Genet , vol.122 , Issue.3-4 , pp. 219-236
    • Lotery, A.1    Trump, D.2
  • 6
    • 79958098579 scopus 로고    scopus 로고
    • Parallel findings in age-related macular degeneration and Alzheimer's disease
    • Ohno-Matsui K. Parallel findings in age-related macular degeneration and Alzheimer's disease. Prog Retin Eye Res 2011; 30(4): 217-238.
    • (2011) Prog Retin Eye Res , vol.30 , Issue.4 , pp. 217-238
    • Ohno-Matsui, K.1
  • 7
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297(5580): 353-356.
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 8
    • 84857642949 scopus 로고    scopus 로고
    • The toxic abeta oligomer and Alzheimer's disease: An emperor in need of clothes
    • Benilova I, Karran E, De SB. The toxic Abeta oligomer and Alzheimer's disease: an emperor in need of clothes. Nat Neurosci 2012; 15(3): 349-357.
    • (2012) Nat Neurosci , vol.15 , Issue.3 , pp. 349-357
    • Benilova, I.1    Karran, E.2    De, S.B.3
  • 12
    • 11144258543 scopus 로고    scopus 로고
    • Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
    • Crabb JW, Miyagi M, Gu X, Shadrach K, West KA, Sakaguchi H et al. Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci USA 2002; 99(23): 14682-14687.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.23 , pp. 14682-14687
    • Crabb, J.W.1    Miyagi, M.2    Gu, X.3    Shadrach, K.4    West, K.A.5    Sakaguchi, H.6
  • 13
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 2002; 134(3): 411-431.
    • (2002) Am J Ophthalmol , vol.134 , Issue.3 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 14
    • 26444478610 scopus 로고    scopus 로고
    • The potential role of amyloid beta in the pathogenesis of age-related macular degeneration
    • Yoshida T, Ohno-Matsui K, Ichinose S, Sato T, Iwata N, Saido TC et al. The potential role of amyloid beta in the pathogenesis of age-related macular degeneration. J Clin Invest 2005; 115(10): 2793-2800.
    • (2005) J Clin Invest , vol.115 , Issue.10 , pp. 2793-2800
    • Yoshida, T.1    Ohno-Matsui, K.2    Ichinose, S.3    Sato, T.4    Iwata, N.5    Saido, T.C.6
  • 15
    • 79960495664 scopus 로고    scopus 로고
    • Development and expression of amyloid-beta peptide 42 in retinal ganglion cells in rats
    • Wang J, Zhu C, Xu Y, Liu B, Wang M, Wu K. Development and expression of amyloid-beta peptide 42 in retinal ganglion cells in rats. Anat Rec (Hoboken) 2011; 294(8): 1401-1405.
    • (2011) Anat Rec (Hoboken) , vol.294 , Issue.8 , pp. 1401-1405
    • Wang, J.1    Zhu, C.2    Xu, Y.3    Liu, B.4    Wang, M.5    Wu, K.6
  • 16
    • 0025219026 scopus 로고
    • Genomic organization of the human amyloid beta-protein precursor gene
    • Yoshikai S, Sasaki H, Doh-ura K, Furuya H, Sakaki Y. Genomic organization of the human amyloid beta-protein precursor gene. Gene 1990; 87(2): 257-263.
    • (1990) Gene , vol.87 , Issue.2 , pp. 257-263
    • Yoshikai, S.1    Sasaki, H.2    Doh-Ura, K.3    Furuya, H.4    Sakaki, Y.5
  • 17
    • 84878915977 scopus 로고    scopus 로고
    • Redundancy and divergence in the amyloid precursor protein family
    • Shariati SA, De SB. Redundancy and divergence in the amyloid precursor protein family. FEBS Lett 2013; 587(13): 2036-2045.
    • (2013) FEBS Lett , vol.587 , Issue.13 , pp. 2036-2045
    • Shariati, S.A.1    De, S.B.2
  • 18
    • 0026760261 scopus 로고
    • Production of the Alzheimer amyloid beta protein by normal proteolytic processing
    • Shoji M, Golde TE, Ghiso J, Cheung TT, Estus S, Shaffer LM et al. Production of the Alzheimer amyloid beta protein by normal proteolytic processing. Science 1992; 258(5079): 126-129.
    • (1992) Science , vol.258 , Issue.5079 , pp. 126-129
    • Shoji, M.1    Golde, T.E.2    Ghiso, J.3    Cheung, T.T.4    Estus, S.5    Shaffer, L.M.6
  • 20
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
    • Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 2007; 8(2): 101-112.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.2 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 21
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
    • Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos L Jr., Eckman C et al. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 1994; 264(5163): 1336-1340.
    • (1994) Science , vol.264 , Issue.5163 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.D.3    Odaka, A.4    Otvos, L.5    Eckman, C.6
  • 22
    • 0026745610 scopus 로고
    • Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases betaprotein production
    • Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P et al. Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases betaprotein production. Nature 1992; 360(6405): 672-674.
    • (1992) Nature , vol.360 , Issue.6405 , pp. 672-674
    • Citron, M.1    Oltersdorf, T.2    Haass, C.3    McConlogue, L.4    Hung, A.Y.5    Seubert, P.6
  • 23
    • 77951060145 scopus 로고    scopus 로고
    • Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process
    • De SB. Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process. Physiol Rev 2010; 90(2): 465-494.
    • (2010) Physiol Rev , vol.90 , Issue.2 , pp. 465-494
    • De, S.B.1
  • 24
    • 79957919528 scopus 로고    scopus 로고
    • Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease
    • Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M et al. Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO J 2011; 30(11): 2255-2265.
    • (2011) EMBO J , vol.30 , Issue.11 , pp. 2255-2265
    • Kumar, S.1    Rezaei-Ghaleh, N.2    Terwel, D.3    Thal, D.R.4    Richard, M.5    Hoch, M.6
  • 25
    • 27144447811 scopus 로고    scopus 로고
    • Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40
    • Kim W, Hecht MH. Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40. J Biol Chem 2005; 280(41): 35069-35076.
    • (2005) J Biol Chem , vol.280 , Issue.41 , pp. 35069-35076
    • Kim, W.1    Hecht, M.H.2
  • 27
    • 37249017468 scopus 로고    scopus 로고
    • Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity
    • Luheshi LM, Tartaglia GG, Brorsson AC, Pawar AP, Watson IE, Chiti F et al. Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity. PLoS Biol 2007; 5(11): e290.
    • (2007) PLoS Biol , vol.5 , Issue.11 , pp. e290
    • Luheshi, L.M.1    Tartaglia, G.G.2    Brorsson, A.C.3    Pawar, A.P.4    Watson, I.E.5    Chiti, F.6
  • 28
    • 0034658615 scopus 로고    scopus 로고
    • Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of betaamyloid peptide
    • Ward RV, Jennings KH, Jepras R, Neville W, Owen DE, Hawkins J et al. Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of betaamyloid peptide. Biochem J 2000; 348(Pt 1): 137-144.
    • (2000) Biochem J , vol.348 , pp. 137-144
    • Ward, R.V.1    Jennings, K.H.2    Jepras, R.3    Neville, W.4    Owen, D.E.5    Hawkins, J.6
  • 29
    • 0027258525 scopus 로고
    • The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
    • Jarrett JT, Berger EP, Lansbury PT Jr.. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993; 32(18): 4693-4697.
    • (1993) Biochemistry , vol.32 , Issue.18 , pp. 4693-4697
    • Jarrett, J.T.1    Berger, E.P.2    Lansbury, P.T.J.R.3
  • 30
    • 20544466133 scopus 로고    scopus 로고
    • Evidence of the existence of micelles in the fibrillogenesis of beta-amyloid peptide
    • Sabate R, Estelrich J. Evidence of the existence of micelles in the fibrillogenesis of beta-amyloid peptide. J Phys Chem B 2005; 109(21): 11027-11032.
    • (2005) J Phys Chem B , vol.109 , Issue.21 , pp. 11027-11032
    • Sabate, R.1    Estelrich, J.2
  • 32
    • 84860389674 scopus 로고    scopus 로고
    • Amyloid-beta forms fibrils by nucleated conformational conversion of oligomers
    • Lee J, Culyba EK, Powers ET, Kelly JW. Amyloid-beta forms fibrils by nucleated conformational conversion of oligomers. Nat Chem Biol 2011; 7(9): 602-609.
    • (2011) Nat Chem Biol , vol.7 , Issue.9 , pp. 602-609
    • Lee, J.1    Culyba, E.K.2    Powers, E.T.3    Kelly, J.W.4
  • 33
    • 11544279355 scopus 로고    scopus 로고
    • Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
    • Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 1998; 95(11): 6448-6453.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.11 , pp. 6448-6453
    • Lambert, M.P.1    Barlow, A.K.2    Chromy, B.A.3    Edwards, C.4    Freed, R.5    Liosatos, M.6
  • 34
    • 0032590054 scopus 로고    scopus 로고
    • Soluble pool of abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
    • McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K et al. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 1999; 46(6): 860-866.
    • (1999) Ann Neurol , vol.46 , Issue.6 , pp. 860-866
    • McLean, C.A.1    Cherny, R.A.2    Fraser, F.W.3    Fuller, S.J.4    Smith, M.J.5    Beyreuther, K.6
  • 35
    • 77951928742 scopus 로고    scopus 로고
    • The presence of sodium dodecyl sulphate-stable abeta dimers is strongly associated with Alzheimer-type dementia
    • Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM et al. The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. Brain 2010; 133(Pt 5): 1328-1341.
    • (2010) Brain , vol.133 , pp. 1328-1341
    • Mc Donald, J.M.1    Savva, G.M.2    Brayne, C.3    Welzel, A.T.4    Forster, G.5    Shankar, G.M.6
  • 36
    • 78650331032 scopus 로고    scopus 로고
    • The effect of Alzheimer's abeta aggregation state on the permeation of biomimetic lipid vesicles
    • Williams TL, Day IJ, Serpell LC. The effect of Alzheimer's Abeta aggregation state on the permeation of biomimetic lipid vesicles. Langmuir 2010; 26(22): 17260-17268.
    • (2010) Langmuir , vol.26 , Issue.22 , pp. 17260-17268
    • Williams, T.L.1    Day, I.J.2    Serpell, L.C.3
  • 37
    • 84873809834 scopus 로고    scopus 로고
    • Single molecule characterization of the interactions between amyloid-beta peptides and the membranes of hippocampal cells
    • Narayan P, Ganzinger KA, McColl J, Weimann L, Meehan S, Qamar S et al. Single molecule characterization of the interactions between amyloid-beta peptides and the membranes of hippocampal cells. J Am Chem Soc 2013; 135 (4): 1491-1498.
    • (2013) J Am Chem Soc , vol.135 , Issue.4 , pp. 1491-1498
    • Narayan, P.1    Ganzinger, K.A.2    McColl, J.3    Weimann, L.4    Meehan, S.5    Qamar, S.6
  • 38
    • 50949097728 scopus 로고    scopus 로고
    • Oligomer-specific abeta toxicity in cell models is mediated by selective uptake
    • Chafekar SM, Baas F, Scheper W. Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake. Biochim Biophys Acta 2008; 1782(9): 523-531.
    • (2008) Biochim Biophys Acta , vol.1782 , Issue.9 , pp. 523-531
    • Chafekar, S.M.1    Baas, F.2    Scheper, W.3
  • 39
    • 66149104055 scopus 로고    scopus 로고
    • Amyloid goes global
    • Bezprozvanny I. Amyloid goes global. Sci Signal 2009; 2 (63): pe16.
    • (2009) Sci Signal , vol.2 , Issue.63 , pp. pe16
    • Bezprozvanny, I.1
  • 40
    • 70350061949 scopus 로고    scopus 로고
    • Multimodal techniques for diagnosis and prognosis of Alzheimer's disease
    • Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature 2009; 461(7266): 916-922.
    • (2009) Nature , vol.461 , Issue.7266 , pp. 916-922
    • Perrin, R.J.1    Fagan, A.M.2    Holtzman, D.M.3
  • 41
    • 0025991945 scopus 로고
    • Amyloid protein and Alzheimer's disease
    • Selkoe DJ. Amyloid protein and Alzheimer's disease. Sci Am 1991; 265(5): 68-6 78.
    • (1991) Sci Am , vol.265 , Issue.5 , pp. 68-678
    • Selkoe, D.J.1
  • 42
    • 80053589341 scopus 로고    scopus 로고
    • Membrane and surface interactions of Alzheimer's abeta peptide-insights into the mechanism of cytotoxicity
    • Williams TL, Serpell LC. Membrane and surface interactions of Alzheimer's Abeta peptide-insights into the mechanism of cytotoxicity. FEBS J 2011; 278(20): 3905-3917.
    • (2011) FEBS J , vol.278 , Issue.20 , pp. 3905-3917
    • Williams, T.L.1    Serpell, L.C.2
  • 43
    • 84863986886 scopus 로고    scopus 로고
    • Oligomeric intermediates in amyloid formation: Structure determination and mechanisms of toxicity
    • Fandrich M. Oligomeric intermediates in amyloid formation: structure determination and mechanisms of toxicity. J Mol Biol 2012; 421(4-5): 427-440.
    • (2012) J Mol Biol , vol.421 , Issue.4-5 , pp. 427-440
    • Fandrich, M.1
  • 44
    • 0032837741 scopus 로고    scopus 로고
    • The levels of soluble versus insoluble brain abeta distinguish Alzheimer's disease from normal and pathologic aging
    • Wang J, Dickson DW, Trojanowski JQ, Lee VM. The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging. Exp Neurol 1999; 158(2): 328-337.
    • (1999) Exp Neurol , vol.158 , Issue.2 , pp. 328-337
    • Wang, J.1    Dickson, D.W.2    Trojanowski, J.Q.3    Lee, V.M.4
  • 46
    • 84872765430 scopus 로고    scopus 로고
    • Peptides is associated with early changes in microtubuleassociated protein 2 in neurites and synapses
    • peptides is associated with early changes in microtubuleassociated protein 2 in neurites and synapses. PLoS One 2013; 8(1): e51965.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e51965
  • 47
    • 33846633336 scopus 로고    scopus 로고
    • Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
    • Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M et al. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 2007; 27(4): 796-807.
    • (2007) J Neurosci , vol.27 , Issue.4 , pp. 796-807
    • Lacor, P.N.1    Buniel, M.C.2    Furlow, P.W.3    Clemente, A.S.4    Velasco, P.T.5    Wood, M.6
  • 48
    • 0032983254 scopus 로고    scopus 로고
    • Presence of sodium dodecyl sulfate-stable amyloid beta-protein dimers in the hippocampus CA1 not exhibiting neurofibrillary tangle formation
    • Funato H, Enya M, Yoshimura M, Morishima-Kawashima M, Ihara Y. Presence of sodium dodecyl sulfate-stable amyloid beta-protein dimers in the hippocampus CA1 not exhibiting neurofibrillary tangle formation. Am J Pathol 1999; 155(1): 23-28.
    • (1999) Am J Pathol , vol.155 , Issue.1 , pp. 23-28
    • Funato, H.1    Enya, M.2    Yoshimura, M.3    Morishima-Kawashima, M.4    Ihara, Y.5
  • 50
    • 77953782590 scopus 로고    scopus 로고
    • Membrane localization of beta-amyloid 1-42 in lysosomes: A possible mechanism for lysosome labilization
    • Liu RQ, Zhou QH, Ji SR, Zhou Q, Feng D, Wu Y et al. Membrane localization of beta-amyloid 1-42 in lysosomes: a possible mechanism for lysosome labilization. J Biol Chem 2010; 285(26): 19986-19996.
    • (2010) J Biol Chem , vol.285 , Issue.26 , pp. 19986-19996
    • Liu, R.Q.1    Zhou, Q.H.2    Ji, S.R.3    Zhou, Q.4    Feng, D.5    Wu, Y.6
  • 51
    • 84555187703 scopus 로고    scopus 로고
    • Visualization of co-localization in Abeta42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death
    • Soura V, Stewart-Parker M, Williams TL, Ratnayaka A, Atherton J, Gorringe K et al. Visualization of co-localization in Abeta42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death. Biochem J 2012; 441(2): 579-590.
    • (2012) Biochem J , vol.441 , Issue.2 , pp. 579-590
    • Soura, V.1    Stewart-Parker, M.2    Williams, T.L.3    Ratnayaka, A.4    Atherton, J.5    Gorringe, K.6
  • 52
    • 67349129779 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis and Alzheimer's disease: An update
    • Wu F, Yao PJ. Clathrin-mediated endocytosis and Alzheimer's disease: an update. Ageing Res Rev 2009; 8(3): 147-149.
    • (2009) Ageing Res Rev , vol.8 , Issue.3 , pp. 147-149
    • Wu, F.1    Yao, P.J.2
  • 54
    • 79952007060 scopus 로고    scopus 로고
    • internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons
    • internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons. Neuroscience 2011; 178: 181-188.
    • (2011) Neuroscience , vol.178 , pp. 181-188
  • 56
    • 0037015020 scopus 로고    scopus 로고
    • The Alzheimer's a beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
    • Johnson LV, Leitner WP, Rivest AJ, Staples MK, Radeke MJ, Anderson DH. The Alzheimer's A beta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc Natl Acad Sci USA 2002; 99(18): 11830-11835.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.18 , pp. 11830-11835
    • Johnson, L.V.1    Leitner, W.P.2    Rivest, A.J.3    Staples, M.K.4    Radeke, M.J.5    Anderson, D.H.6
  • 58
    • 84862652157 scopus 로고    scopus 로고
    • Elevated amyloid beta production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid beta in age-related macular degeneration
    • Wang J, Ohno-Matsui K, Morita I. Elevated amyloid beta production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid beta in age-related macular degeneration. Biochem Biophys Res Commun 2012; 423(1): 73-78.
    • (2012) Biochem Biophys Res Commun , vol.423 , Issue.1 , pp. 73-78
    • Wang, J.1    Ohno-Matsui, K.2    Morita, I.3
  • 59
    • 0345760069 scopus 로고    scopus 로고
    • Characterization of beta amyloid assemblies in drusen: The deposits associated with aging and age-related macular degeneration
    • AndersonDH, Talaga KC, RivestAJ, Barron E, HagemanGS, Johnson LV. Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration. Exp Eye Res 2004; 78(2): 243-256.
    • (2004) Exp Eye Res , vol.78 , Issue.2 , pp. 243-256
    • Anderson, D.H.1    Talaga, K.C.2    Rivest, A.J.3    Barron, E.4    Hageman, G.S.5    Johnson, L.V.6
  • 60
    • 0026646605 scopus 로고
    • Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
    • Seubert P, Vigo-Pelfrey C, Esch F, Lee M, Dovey H, Davis D et al. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 1992; 359(6393): 325-327.
    • (1992) Nature , vol.359 , Issue.6393 , pp. 325-327
    • Seubert, P.1    Vigo-Pelfrey, C.2    Esch, F.3    Lee, M.4    Dovey, H.5    Davis, D.6
  • 61
    • 79955529460 scopus 로고    scopus 로고
    • Large quantities of abeta peptide are constitutively released during amyloid precursor protein metabolism in vivo and in vitro
    • Moghekar A, Rao S, Li M, Ruben D, Mammen A, Tang X et al. Large quantities of Abeta peptide are constitutively released during amyloid precursor protein metabolism in vivo and in vitro. J Biol Chem 2011; 286(18): 15989-15997.
    • (2011) J Biol Chem , vol.286 , Issue.18 , pp. 15989-15997
    • Moghekar, A.1    Rao, S.2    Li, M.3    Ruben, D.4    Mammen, A.5    Tang, X.6
  • 62
    • 78049299159 scopus 로고    scopus 로고
    • Viewing ageing eyes: Diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages
    • Hoh KJ, Lenassi E, Jeffery G. Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages. PLoS One 2010; 5(10): e13127.
    • (2010) PLoS One , vol.5 , Issue.10 , pp. e13127
    • Hoh, K.J.1    Lenassi, E.2    Jeffery, G.3
  • 63
    • 32444450909 scopus 로고    scopus 로고
    • Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers
    • Luibl V, Isas JM, Kayed R, Glabe CG, Langen R, Chen J. Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. J Clin Invest 2006; 116(2): 378-385.
    • (2006) J Clin Invest , vol.116 , Issue.2 , pp. 378-385
    • Luibl, V.1    Isas, J.M.2    Kayed, R.3    Glabe, C.G.4    Langen, R.5    Chen, J.6
  • 65
    • 84875661147 scopus 로고    scopus 로고
    • Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: Implications for inflammasome activation in age-related macular degeneration
    • Liu RT, Gao J, Cao S, Sandhu N, Cui JZ, Chou CL et al. Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration. Invest Ophthalmol Vis Sci 2013; 54(3): 2225-2237.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , Issue.3 , pp. 2225-2237
    • Liu, R.T.1    Gao, J.2    Cao, S.3    Sandhu, N.4    Cui, J.Z.5    Chou, C.L.6
  • 67
    • 0037975774 scopus 로고    scopus 로고
    • Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas
    • Dentchev T, Milam AH, Lee VM, Trojanowski JQ, Dunaief JL. Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas. Mol Vis 2003; 9: 184-190.
    • (2003) Mol Vis , vol.9 , pp. 184-190
    • Dentchev, T.1    Milam, A.H.2    Lee, V.M.3    Trojanowski, J.Q.4    Dunaief, J.L.5
  • 68
    • 77449129224 scopus 로고    scopus 로고
    • Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells
    • Kurji KH, Cui JZ, Lin T, Harriman D, Prasad SS, Kojic L et al. Microarray analysis identifies changes in inflammatory gene expression in response to amyloid-beta stimulation of cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2010; 51(2): 1151-1163.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.2 , pp. 1151-1163
    • Kurji, K.H.1    Cui, J.Z.2    Lin, T.3    Harriman, D.4    Prasad, S.S.5    Kojic, L.6
  • 69
    • 84883562573 scopus 로고    scopus 로고
    • Abeta-induced senescent retinal pigment epithelial cells create a proinflammatory microenvironment in AMD
    • Cao L, Wang H, Wang F, Xu D, Liu F, Liu C. Abeta-induced senescent retinal pigment epithelial cells create a proinflammatory microenvironment in AMD. Invest Ophthalmol Vis Sci 2013; 54(5): 3738-3750.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , Issue.5 , pp. 3738-3750
    • Cao, L.1    Wang, H.2    Wang, F.3    Xu, D.4    Liu, F.5    Liu, C.6
  • 70
    • 0035219629 scopus 로고    scopus 로고
    • Retinal pigment epithelium-immune system interactions: Cytokine production and cytokine-induced changes
    • Holtkamp GM, Kijlstra A, Peek R, de Vos AF. Retinal pigment epithelium-immune system interactions: cytokine production and cytokine-induced changes. Prog Retin Eye Res 2001; 20(1): 29-48.
    • (2001) Prog Retin Eye Res , vol.20 , Issue.1 , pp. 29-48
    • Holtkamp, G.M.1    Kijlstra, A.2    Peek, R.3    De Vos, A.F.4
  • 71
    • 34948822892 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells
    • Yang D, Elner SG, Bian ZM, Till GO, Petty HR, Elner VM. Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells. Exp Eye Res 2007; 85(4): 462-472.
    • (2007) Exp Eye Res , vol.85 , Issue.4 , pp. 462-472
    • Yang, D.1    Elner, S.G.2    Bian, Z.M.3    Till, G.O.4    Petty, H.R.5    Elner, V.M.6
  • 72
    • 84863775431 scopus 로고    scopus 로고
    • IL-33 is induced by amyloid-beta stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells
    • Liu XC, Liu XF, Jian CX, Li CJ, He SZ. IL-33 is induced by amyloid-beta stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells. Inflammation 2012; 35(2): 776-784.
    • (2012) Inflammation , vol.35 , Issue.2 , pp. 776-784
    • Liu, X.C.1    Liu, X.F.2    Jian, C.X.3    Li, C.J.4    He, S.Z.5
  • 73
    • 63549133336 scopus 로고    scopus 로고
    • Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells
    • Bruban J, Glotin AL, Dinet V, Chalour N, Sennlaub F, Jonet L et al. Amyloid-beta(1-42) alters structure and function of retinal pigmented epithelial cells. Aging Cell 2009; 8(2): 162-177.
    • (2009) Aging Cell , vol.8 , Issue.2 , pp. 162-177
    • Bruban, J.1    Glotin, A.L.2    Dinet, V.3    Chalour, N.4    Sennlaub, F.5    Jonet, L.6
  • 74
    • 84860883878 scopus 로고    scopus 로고
    • DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
    • Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012; 149(4): 847-859.
    • (2012) Cell , vol.149 , Issue.4 , pp. 847-859
    • Tarallo, V.1    Hirano, Y.2    Gelfand, B.D.3    Dridi, S.4    Kerur, N.5    Kim, Y.6
  • 75
    • 77953098533 scopus 로고    scopus 로고
    • Induction of amyloid precursor protein by the neurotoxic peptide, amyloid-beta 25-35, causes retinal ganglion cell death
    • Tsuruma K, Tanaka Y, Shimazawa M, Hara H. Induction of amyloid precursor protein by the neurotoxic peptide, amyloid-beta 25-35, causes retinal ganglion cell death. J Neurochem 2010; 113(6): 1545-1554.
    • (2010) J Neurochem , vol.113 , Issue.6 , pp. 1545-1554
    • Tsuruma, K.1    Tanaka, Y.2    Shimazawa, M.3    Hara, H.4
  • 77
    • 84860389399 scopus 로고    scopus 로고
    • Age-related macular degeneration and the complement system
    • Khandhadia S, Cipriani V, Yates JR, Lotery AJ. Age-related macular degeneration and the complement system. Immunobiology 2012; 217(2): 127-146.
    • (2012) Immunobiology , vol.217 , Issue.2 , pp. 127-146
    • Khandhadia, S.1    Cipriani, V.2    Yates, J.R.3    Lotery, A.J.4
  • 78
    • 77249147331 scopus 로고    scopus 로고
    • The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
    • Anderson DH, RadekeMJ, Gallo NB, Chapin EA, Johnson PT, Curletti CR et al. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res 2010; 29(2): 95-112.
    • (2010) Prog Retin Eye Res , vol.29 , Issue.2 , pp. 95-112
    • Anderson, D.H.1    Radeke, M.J.2    Gallo, N.B.3    Chapin, E.A.4    Johnson, P.T.5    Curletti, C.R.6
  • 79
    • 0032479929 scopus 로고    scopus 로고
    • Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide
    • Bradt BM, Kolb WP, Cooper NR. Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide. J Exp Med 1998; 188(3): 431-438.
    • (1998) J Exp Med , vol.188 , Issue.3 , pp. 431-438
    • Bradt, B.M.1    Kolb, W.P.2    Cooper, N.R.3
  • 81
    • 21044453724 scopus 로고    scopus 로고
    • A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
    • Hageman GS, Anderson DH, Johnson LV, Hancox LS, Taiber AJ, Hardisty LI et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. Proc Natl Acad Sci USA 2005; 102(20): 7227-7232.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.20 , pp. 7227-7232
    • Hageman, G.S.1    Anderson, D.H.2    Johnson, L.V.3    Hancox, L.S.4    Taiber, A.J.5    Hardisty, L.I.6
  • 82
    • 3543134126 scopus 로고    scopus 로고
    • Matrix metalloproteinases as modulators of inflammation and innate immunity
    • Parks WC, Wilson CL, Lopez-Boado YS. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol 2004; 4(8): 617-629.
    • (2004) Nat Rev Immunol , vol.4 , Issue.8 , pp. 617-629
    • Parks, W.C.1    Wilson, C.L.2    Lopez-Boado, Y.S.3
  • 83
    • 8744276616 scopus 로고    scopus 로고
    • Amyloid beta-peptide (1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain
    • Butterfield DA, Boyd-Kimball D. Amyloid beta-peptide (1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain. Brain Pathol 2004; 14(4): 426-432.
    • (2004) Brain Pathol , vol.14 , Issue.4 , pp. 426-432
    • Butterfield, D.A.1    Boyd-Kimball, D.2
  • 84
    • 84861600073 scopus 로고    scopus 로고
    • Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration
    • Kinnunen K, Petrovski G, Moe MC, Berta A, Kaarniranta K. Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration. Acta Ophthalmol 2012; 90(4): 299-309.
    • (2012) Acta Ophthalmol , vol.90 , Issue.4 , pp. 299-309
    • Kinnunen, K.1    Petrovski, G.2    Moe, M.C.3    Berta, A.4    Kaarniranta, K.5
  • 85
    • 84875094879 scopus 로고    scopus 로고
    • Mitochondrial and nuclear DNA damage and repair in agerelated macular degeneration
    • Blasiak J, Glowacki S, Kauppinen A, Kaarniranta K. Mitochondrial and nuclear DNA damage and repair in agerelated macular degeneration. Int J Mol Sci 2013; 14(2): 2996-3010.
    • (2013) Int J Mol Sci , vol.14 , Issue.2 , pp. 2996-3010
    • Blasiak, J.1    Glowacki, S.2    Kauppinen, A.3    Kaarniranta, K.4
  • 86
    • 84874954140 scopus 로고    scopus 로고
    • Amyloid-beta increases capillary bed density in the adult zebrafish retina
    • Cunvong K, Huffmire D, Ethell DW, Cameron DJ. Amyloid-beta increases capillary bed density in the adult zebrafish retina. Invest Ophthalmol Vis Sci 2013; 54(2): 1516-1521.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , Issue.2 , pp. 1516-1521
    • Cunvong, K.1    Huffmire, D.2    Ethell, D.W.3    Cameron, D.J.4
  • 88
    • 80052330506 scopus 로고    scopus 로고
    • Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease
    • Biron KE, Dickstein DL, Gopaul R, Jefferies WA. Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. PLoS One 2011; 6(8): e23789.
    • (2011) PLoS One , vol.6 , Issue.8 , pp. e23789
    • Biron, K.E.1    Dickstein, D.L.2    Gopaul, R.3    Jefferies, W.A.4
  • 90
    • 81255168210 scopus 로고    scopus 로고
    • studies
    • studies. Hum Mutat 2011; 32(12): 1407-1416.
    • (2011) Hum Mutat , vol.32 , Issue.12 , pp. 1407-1416
  • 92
    • 77952472259 scopus 로고    scopus 로고
    • Apolipoprotein e genotype is associated with macular pigment optical density
    • Loane E, McKay GJ, Nolan JM, Beatty S. Apolipoprotein E genotype is associated with macular pigment optical density. Invest Ophthalmol Vis Sci 2010; 51(5): 2636-2643.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.5 , pp. 2636-2643
    • Loane, E.1    McKay, G.J.2    Nolan, J.M.3    Beatty, S.4
  • 93
    • 12044254746 scopus 로고
    • Binding of human apolipoprotein e to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
    • Strittmatter WJ, Weisgraber KH, Huang DY, Dong LM, Salvesen GS, Pericak-Vance M et al. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993; 90(17): 8098-8102.
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.17 , pp. 8098-8102
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Huang, D.Y.3    Dong, L.M.4    Salvesen, G.S.5    Pericak-Vance, M.6
  • 95
    • 79955663093 scopus 로고    scopus 로고
    • High ability of apolipoprotein e4 to stabilize amyloid-beta peptide oligomers, the pathological entities responsible for Alzheimer's disease
    • Cerf E, Gustot A, Goormaghtigh E, Ruysschaert JM, Raussens V. High ability of apolipoprotein E4 to stabilize amyloid-beta peptide oligomers, the pathological entities responsible for Alzheimer's disease. FASEB J 2011; 25(5): 1585-1595.
    • (2011) FASEB J , vol.25 , Issue.5 , pp. 1585-1595
    • Cerf, E.1    Gustot, A.2    Goormaghtigh, E.3    Ruysschaert, J.M.4    Raussens, V.5
  • 97
    • 84867600744 scopus 로고    scopus 로고
    • Rational heterodoxy: Cholesterol reformation of the amyloid doctrine
    • Castello MA, Soriano S. Rational heterodoxy: cholesterol reformation of the amyloid doctrine. Ageing Res Rev 2013; 12(1): 282-288.
    • (2013) Ageing Res Rev , vol.12 , Issue.1 , pp. 282-288
    • Castello, M.A.1    Soriano, S.2
  • 98
    • 84864823300 scopus 로고    scopus 로고
    • Cholesterol enhances amyloid beta deposition in mouse retina by modulating the activities of abeta-regulating enzymes in retinal pigment epithelial cells
    • Wang J, Ohno-Matsui K, Morita I. Cholesterol enhances amyloid beta deposition in mouse retina by modulating the activities of Abeta-regulating enzymes in retinal pigment epithelial cells. Biochem Biophys Res Commun 2012; 424(4): 704-709.
    • (2012) Biochem Biophys Res Commun , vol.424 , Issue.4 , pp. 704-709
    • Wang, J.1    Ohno-Matsui, K.2    Morita, I.3
  • 99
    • 80051795545 scopus 로고    scopus 로고
    • Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina
    • Dasari B, Prasanthi JR, Marwarha G, Singh BB, Ghribi O. Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. BMC Ophthalmol 2011; 11: 22.
    • (2011) BMC Ophthalmol , vol.11 , pp. 22
    • Dasari, B.1    Prasanthi, J.R.2    Marwarha, G.3    Singh, B.B.4    Ghribi, O.5
  • 100
  • 101
    • 79961005068 scopus 로고    scopus 로고
    • Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
    • Ding JD, Johnson LV, Herrmann R, Farsiu S, Smith SG, Groelle M et al. Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proc Natl Acad Sci USA 2011; 108(28): E279-E287.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.28 , pp. E279-E287
    • Ding, J.D.1    Johnson, L.V.2    Herrmann, R.3    Farsiu, S.4    Smith, S.G.5    Groelle, M.6
  • 103
    • 84901770743 scopus 로고    scopus 로고
    • Choroidal thinning as a new finding in Alzheimer's disease: Evidence from enhanced depth imaging spectral domain optical coherence tomography
    • Gharbiya M, Trebbastoni A, Parisi F, Manganiello S, Cruciani F, D'Antonio F et al. Choroidal thinning as a new finding in Alzheimer's disease: evidence from enhanced depth imaging spectral domain optical coherence tomography. J Alzheimers Dis 2014; 40(4): 907-917.
    • (2014) J Alzheimers Dis , vol.40 , Issue.4 , pp. 907-917
    • Gharbiya, M.1    Trebbastoni, A.2    Parisi, F.3    Manganiello, S.4    Cruciani, F.5    D'Antonio, F.6


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