Phenotypic switch of CD8+ T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells

European Journal of Immunology

Volumn 45, Issue 8, 2015, Pages 2263-2275

  de silly, Romain Vuillefroy ^a   Ducimetière, Laura ^a   Yacoub maroun, Céline ^a   Dietrich, Pierre Yves ^a   Derouazi, Madiha ^a   Walker, Paul R ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

CD8+ T cell; Hypoxia; IL 10; Oxygen; T cell reactivation

Indexed keywords

CD137 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; OXYGEN; IL10 PROTEIN, MOUSE; IL2RA PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; EFFECTOR CELL; HYPOXIA; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; LYMPH NODE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; OXYGEN TENSION; PHENOTYPE; PRIORITY JOURNAL; TUMOR ASSOCIATED LEUKOCYTE; UPREGULATION; ANIMAL; CELL HYPOXIA; EXPERIMENTAL NEOPLASM; GENETICS; HUMAN; IMMUNOLOGY; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD137; CD8-POSITIVE T-LYMPHOCYTES; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, TRANSGENIC; NEOPLASMS, EXPERIMENTAL;

EID: 84938969818     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445284     Document Type: Article

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