Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis

Molecular Immunology

Volumn 46, Issue 16, 2009, Pages 3345-3357

  Aherne, Carol M ^a   McMorrow, Jason ^a   Kane, David ^b   FitzGerald, Oliver ^b   Mix, Kimberlee S ^a   Murphy, Evelyn P ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

Author keywords

Arthritis; Chemokines; Cytokines; Gene expression; Orphan nuclear receptors; Promoter activity; Transactivation

Indexed keywords

AUTACOID; CELL NUCLEUS RECEPTOR; DNA; I KAPPA B KINASE; INTERLEUKIN 8; MESSENGER RNA; METHOTREXATE; NUCLEAR RECEPTOR NR4A2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTHRITIS; ARTICLE; CELL ACTIVATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE RELEASE; DIMERIZATION; DNA BINDING; ENHANCER REGION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR INTERACTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SYNOVIOCYTE; SYNOVIUM; TRANSACTIVATION; TRANSCRIPTION INITIATION; TREATMENT OUTCOME;

ACTIVE TRANSPORT, CELL NUCLEUS; ARTHRITIS; CELL NUCLEUS; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; MALE; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70349443394     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.07.019     Document Type: Article

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