The effect of A 2A adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation

Inflammation

Volumn 35, Issue 2, 2012, Pages 614-622

  Williams, Adrienne J ^a   Cronstein, Bruce N ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

A 2A adenosine receptor; Chemokine receptor migration; Macrophage

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2A RECEPTOR; CHEMOKINE RECEPTOR CCR7; MESSENGER RNA;

ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MACROPHAGE MIGRATION; MACROPHAGE MIGRATION INHIBITION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; THP1 MACROPHAGE;

ADENOSINE; ADENOSINE A2 RECEPTOR AGONISTS; ADENOSINE A2 RECEPTOR ANTAGONISTS; CELL LINE; CELL MOVEMENT; CHEMOKINE CCL21; HUMANS; INFLAMMATION; MACROPHAGES; PHENETHYLAMINES; RECEPTORS, ADENOSINE A2; RECEPTORS, CCR7; RNA, MESSENGER; TRIAZINES; TRIAZOLES;

EID: 84863776052     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9353-1     Document Type: Article

References (39)

1. Lord, R.S., and Y.V. Bobryshev. 2002. Hallmarks of atherosclerotic lesion development with special reference to immune inflammatory mechanisms. Cardiovascular Surgery 10: 405-414. (Pubitemid 35299943)
2. Lusis, A.J. 2000. Atherosclerosis. Nature 407: 233-241.
3. Steinberg, D. 2002. Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime. Nature Medicine 8: 1211-1217. (Pubitemid 35373551)
4. Takahashi, K., M. Takeya, and N. Sakashita. 2002. Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals. Medical Electron Microscopy 35: 179-203. (Pubitemid 36205679)
5. Campbell, D.J., C.H. Kim, and E.C. Butcher. 2003. Chemokines in the systemic organization of immunity. Immunological Reviews 195: 58-71. (Pubitemid 37153453)
6. Lucas, A.D., and D.R. Greaves. 2001. Atherosclerosis: role of chemokines and macrophages. Expert Reviews in Molecular Medicine 3: 1-18.
7. Zlotnik, A., O. Yoshie, and H. Nomiyama. 2006. The chemokine and chemokine receptor superfamilies and their molecular evolution. Genome Biology 7: 243.
8. Bours, M.J., E.L. Swennen, F. Di Virgilio, B.N. Cronstein, and P.C. Dagnelie. 2006. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacology & Therapeutics 112: 358-404. (Pubitemid 44486409)
9. Hasko, G., P. Pacher, E.A. Deitch, and E.S. Vizi. 2007. Shaping of monocyte and macrophage function by adenosine receptors. Pharmacology & Therapeutics 113: 264-275. (Pubitemid 46149045)
10. McPherson, J.A., K.G. Barringhaus, G.G. Bishop, J.M. Sanders, J. M. Rieger, S.E. Hesselbacher, L.W. Gimple, E.R. Powers, T. Macdonald, G. Sullivan, et al. 2001. Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model. Arteriosclerosis, Thrombosis, and Vascular Biology 21: 791-796. (Pubitemid 32448770)
11. Fredholm, B.B. 2007. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death and Differentiation 14: 1315-1323. (Pubitemid 46965261)
12. Bingham, T.C., E.A. Fisher, S. Parathath, A.B. Reiss, E.S. Chan, and B.N. Cronstein. 2010. A2A adenosine receptor stimulation decreases foam cell formation by enhancing ABCA1-dependent cholesterol efflux. Journal of Leukocyte Biology 87: 683-690.
13. Khoa, N.D., M.C. Montesinos, A.B. Reiss, D. Delano, N. Awadallah, and B.N. Cronstein. 2001. Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. Journal of Immunology 167: 4026-4032. (Pubitemid 32910848)
14. Link, A.A., T. Kino, J.A. Worth, J.L. McGuire, M.L. Crane, G.P. Chrousos, R.L. Wilder, and I.J. Elenkov. 2000. Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes. Journal of Immunology 164: 436-442. (Pubitemid 30013019)
15. Reiss, A.B., N.W. Awadallah, S. Malhotra, M.C. Montesinos, E.S. Chan, N.B. Javitt, and B.N. Cronstein. 2001. Immune complexes and IFN-gamma decrease cholesterol 27-hydroxylase in human arterial endothelium and macrophages. Journal of Lipid Research 42: 1913-1922. (Pubitemid 33116723)
16. Thiel, M., and A. Chouker. 1995. Acting via A2 receptors, adenosine inhibits the production of tumor necrosis factor-alpha of endotoxin-stimulated human polymorphonuclear leukocytes. The Journal of Laboratory and Clinical Medicine 126: 275-282.
17. Block, E.T. 2009. Interferon gamma inhibits adenosine A2A receptor function in hepatic stellate cells by downregulating expression of adenylyl cyclase in a STAT1-dependent manner. New York: New York University Department of Basic Medical Sciences.
18. Hofer, S., L. Ivarsson, P. Stoitzner, M. Auffinger, C. Rainer, N. Romani, and C. Heufler. 2003. Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation. The Journal of Investigative Dermatology 121: 300-307. (Pubitemid 36969904)
19. Sun, J., Y. Zhang, M. Yang, Y. Zhang, Q. Xie, Z. Li, Z. Dong, Y. Yang, B. Deng, A. Feng, et al. 2010. Hypoxia induces T-cell apoptosis by inhibiting chemokine C receptor 7 expression: the role of adenosine receptor A(2). Cellular & Molecular Immunology 7: 77-82.
20. Zhang, H., Y. Park, J. Wu, X. Chen, S. Lee, J. Yang, K.C. Dellsperger, and C. Zhang. 2009. Role of TNF-alpha in vascular dysfunction. Clinical Science (London) 116: 219-230.
21. Fredholm, B.B., Y. Chern, R. Franco, and M. Sitkovsky. 2007. Aspects of the general biology of adenosine A2A signaling. Progress in Neurobiology 83: 263-276. (Pubitemid 350102746)
22. Schulte, G., and B.B. Fredholm. 2003. Signalling from adenosine receptors to mitogen-activated protein kinases. Cellular Signalling 15: 813-827. (Pubitemid 36776656)
23. Nguyen, D.K., M.C. Montesinos, A.J. Williams, M. Kelly, and B.N. Cronstein. 2003. Th1 cytokines regulate adenosine receptors and their downstream signaling elements in human microvascular endothelial cells. Journal of Immunology 171: 3991-3998. (Pubitemid 37238673)
24. Reiss, A.B., S.E. Carsons, K. Anwar, S. Rao, S.D. Edelman, H. Zhang, P. Fernandez, B.N. Cronstein, and E.S. Chan. 2008. Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis and Rheumatism 58: 3675-3683.
25. Cronstein, B.N., K.A. Haines, S. Kolasinski, and J. Reibman. 1991. Gs linked receptors (Beta-adrenergic and adenosine A2) uncouple chemoattractant receptors from G proteins. Clinical Research 39: 343A.
26. Cronstein, B.N., K.A. Haines, S. Kolasinski, and J. Reibman. 1992. Occupancy of G alpha s-linked receptors uncouples chemo-attractant receptors from their stimulus-transduction mechanisms in the neutrophil. Blood 80: 1052-1057.
27. Cronstein, B.N., F.R. Rose, and C. Pugliese. 1989. Adenosine, a cytoprotective autocoid: effects of adenosine on neutrophil plasma membrane viscosity and chemoattractant receptor display. Biochimica et Biophysica Acta 987: 176-180. (Pubitemid 20016463)
28. The microRNA registry. [mirbase.org]. Accessed 29 June 2010.
29. Hawkins, P.G., and K.V. Morris. 2008. RNA and transcriptional modulation of gene expression. Cell Cycle 7: 602-607. (Pubitemid 351498998)
30. Maziere, P., and A.J. Enright. 2007. Prediction of microRNA targets. Drug Discovery Today 12: 452-458. (Pubitemid 46795589)
31. Williams, A.E. 2008. Functional aspects of animal microRNAs. Cellular and Molecular Life Sciences 65: 545-562. (Pubitemid 351297689)
32. Bos, J.L. 2006. Epac proteins: multi-purpose cAMP targets. Trends in Biochemical Sciences 31: 680-686. (Pubitemid 44791945)
33. Wolff, J., C. Londos, and D.M. Cooper. 1981. Adenosine receptors and the regulation of adenylate cyclase. Advances in Cyclic Nucleotide Research 14: 199-214.
34. Che, J., E.S. Chan, and B.N. Cronstein. 2007. Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Molecular Pharmacology 72: 1626-1636. (Pubitemid 350146100)
35. Hasko, G., J. Linden, B. Cronstein, and P. Pacher. 2008. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nature Reviews 7: 759-770.
36. Reiss, A.B., K. Anwar, J.T. Merrill, E.S. Chan, N.W. Awadallah, B. N. Cronstein, H. Michael Belmont, E. Belilos, G. Rosenblum, K. Belostocki, et al. 2010. Plasma from systemic lupus patients compromises cholesterol homeostasis: a potential mechanism linking autoimmunity to atherosclerotic cardiovascular disease. Rheumatology International 30: 591-598.
37. Reiss, A.B., C.A. Patel, M.M. Rahman, E.S. Chan, K. Hasneen, M.C. Montesinos, J.D. Trachman, and B.N. Cronstein. 2004. Interferon-gamma impedes reverse cholesterol transport and promotes foam cell transformation in THP-1 human monocytes/macrophages. Medical Science Monitor 10: BR420-425. (Pubitemid 39546030)
38. Reiss, A.B., M.M. Rahman, E.S. Chan, M.C. Montesinos, N.W. Awadallah, and B.N. Cronstein. 2004. Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages. Journal of Leukocyte Biology 76: 727-734. (Pubitemid 39129107)
39. Reiss, A.B., D.W. Wan, K. Anwar, J.T. Merrill, P.A. Wirkowski, N. Shah, B.N. Cronstein, E.S. Chan, and S.E. Carsons. 2009. Enhanced CD36 scavenger receptor expression in THP-1 human monocytes in the presence of lupus plasma: linking autoimmunity and atherosclerosis. Experimental Biology and Medicine (Maywood) 234: 354-360.