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Volumn 26, Issue 3, 2012, Pages 423-437

FOXO1 increases CCL20 to promote NF-κB-dependent lymphocyte chemotaxis

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD BOX CONTAINING PROTEIN O SUBFAMILY 1; FORKHEAD TRANSCRIPTION FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; PROTEIN P50; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84863165430     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1233     Document Type: Article
Times cited : (38)

References (60)
  • 1
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD 2004 Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 114:147-152.
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 2
    • 0033546192 scopus 로고    scopus 로고
    • Phos- phorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
    • Guo S, Rena G, Cichy S, He X, Cohen P, Unterman T 1999 Phos- phorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J Biol Chem 274:17184-17192.
    • (1999) J Biol Chem , vol.274 , pp. 17184-17192
    • Guo, S.1    Rena, G.2    Cichy, S.3    He, X.4    Cohen, P.5    Unterman, T.6
  • 3
    • 0033546439 scopus 로고    scopus 로고
    • Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
    • Rena G, Guo S, Cichy SC, Unterman TG, Cohen P 1999 Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 274:17179-17183.
    • (1999) J Biol Chem , vol.274 , pp. 17179-17183
    • Rena, G.1    Guo, S.2    Cichy, S.C.3    Unterman, T.G.4    Cohen, P.5
  • 4
    • 0033518120 scopus 로고    scopus 로고
    • Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt
    • del Peso L, González VM, Hernández R, Barr FG, Núñez G 1999 Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt. Oncogene 18:7328-7333.
    • (1999) Oncogene , vol.18 , pp. 7328-7333
    • del Peso, L.1    González, V.M.2    Hernández, R.3    Barr, F.G.4    Núñez, G.5
  • 5
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose- 6-phosphatase expression
    • Nakae J, Kitamura T, Silver DL, Accili D 2001 The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose- 6-phosphatase expression. J Clin Invest 108:1359-1367.
    • (2001) J Clin Invest , vol.108 , pp. 1359-1367
    • Nakae, J.1    Kitamura, T.2    Silver, D.L.3    Accili, D.4
  • 6
    • 0034806293 scopus 로고    scopus 로고
    • Differential regulation of endogenous glucose- 6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells
    • Barthel A, Schmoll D, Krüger KD, Bahrenberg G, Walther R, Roth RA, Joost HG 2001 Differential regulation of endogenous glucose- 6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells. Biochem Biophys Res Commun 285:897-902.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 897-902
    • Barthel, A.1    Schmoll, D.2    Krüger, K.D.3    Bahrenberg, G.4    Walther, R.5    Roth, R.A.6    Joost, H.G.7
  • 7
    • 4444246000 scopus 로고    scopus 로고
    • Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
    • Kodama S, Koike C, Negishi M, Yamamoto Y 2004 Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes. Mol Cell Biol 24:7931-7940.
    • (2004) Mol Cell Biol , vol.24 , pp. 7931-7940
    • Kodama, S.1    Koike, C.2    Negishi, M.3    Yamamoto, Y.4
  • 9
    • 67049143907 scopus 로고    scopus 로고
    • FoxO1 and hepatic lipid metabolism
    • Sparks JD, Dong HH 2009 FoxO1 and hepatic lipid metabolism. Curr Opin Lipidol 20:217-226.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 217-226
    • Sparks, J.D.1    Dong, H.H.2
  • 10
    • 45749107163 scopus 로고    scopus 로고
    • A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway
    • de Candia P, Blekhman R, Chabot AE, Oshlack A, Gilad Y 2008 A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway. PLoS One 3:e1670.
    • (2008) PLoS One , vol.3
    • de Candia, P.1    Blekhman, R.2    Chabot, A.E.3    Oshlack, A.4    Gilad, Y.5
  • 11
    • 50949102655 scopus 로고    scopus 로고
    • WatadaH2008 Impact of oxidative stress and peroxisome proliferator-activated receptor γ coactivator- α1in hepatic insulin resistance
    • Kumashiro N, Tamura Y, Uchida T, Ogihara T, Fujitani Y, Hirose T, Mochizuki H, Kawamori R, WatadaH2008 Impact of oxidative stress and peroxisome proliferator-activated receptor γ coactivator- α1in hepatic insulin resistance. Diabetes 57:2083-2091.
    • Diabetes , vol.57 , pp. 2083-2091
    • Kumashiro, N.1    Tamura, Y.2    Uchida, T.3    Ogihara, T.4    Fujitani, Y.5    Hirose, T.6    Mochizuki, H.7    Kawamori, R.8
  • 12
    • 67649213892 scopus 로고    scopus 로고
    • Down-regulation of FoxOdependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells
    • Park SJ, Sohn HY, Yoon J, Park SI 2009 Down-regulation of FoxOdependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells. Cell Signal 21:1495-1503.
    • (2009) Cell Signal , vol.21 , pp. 1495-1503
    • Park, S.J.1    Sohn, H.Y.2    Yoon, J.3    Park, S.I.4
  • 14
    • 57049104503 scopus 로고    scopus 로고
    • Foxo1 increases pro-inflammatory gene expression by inducing C/EBP β in TNF-α-treated adipocytes
    • Ito Y, Daitoku H, Fukamizu A 2009 Foxo1 increases pro-inflammatory gene expression by inducing C/EBP β in TNF-α-treated adipocytes. Biochem Biophys Res Commun 378:290-295.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 290-295
    • Ito, Y.1    Daitoku, H.2    Fukamizu, A.3
  • 17
    • 32144454172 scopus 로고    scopus 로고
    • The many roles of chemokines and chemokine receptors in inflammation
    • Charo IF, Ransohoff RM 2006 The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 354:610-621.
    • (2006) N Engl J Med , vol.354 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 18
    • 77952566640 scopus 로고    scopus 로고
    • The role of chemokines in the recruitment of lymphocytes to the liver
    • Oo YH, Shetty S, Adams DH 2010 The role of chemokines in the recruitment of lymphocytes to the liver. Dig Dis 28:31-44.
    • (2010) Dig Dis , vol.28 , pp. 31-44
    • Oo, Y.H.1    Shetty, S.2    Adams, D.H.3
  • 19
    • 2542428442 scopus 로고    scopus 로고
    • Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells
    • Rot A, von Andrian UH 2004 Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu Rev Immunol 22:891-928.
    • (2004) Annu Rev Immunol , vol.22 , pp. 891-928
    • Rot, A.1    von Andrian, U.H.2
  • 20
    • 11244333168 scopus 로고    scopus 로고
    • Chemokines: Control of primary and memory T-cell traffic
    • Schaerli P, Moser B 2005 Chemokines: control of primary and memory T-cell traffic. Immunol Res 31:57-74.
    • (2005) Immunol Res , vol.31 , pp. 57-74
    • Schaerli, P.1    Moser, B.2
  • 21
    • 77952565960 scopus 로고    scopus 로고
    • Chemokines as immune mediators of liver diseases related to the metabolic syndrome
    • Berres ML, Nellen A, Wasmuth HE 2010 Chemokines as immune mediators of liver diseases related to the metabolic syndrome. Dig Dis 28:192-196.
    • (2010) Dig Dis , vol.28 , pp. 192-196
    • Berres, M.L.1    Nellen, A.2    Wasmuth, H.E.3
  • 23
    • 15644369239 scopus 로고    scopus 로고
    • Molecular cloning of a novel human CC chemokine liver and activation- regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2
    • Hieshima K, Imai T, Opdenakker G, Van Damme J, Kusuda J, Tei H, Sakaki Y, Takatsuki K, Miura R, Yoshie O, Nomiyama H 1997 Molecular cloning of a novel human CC chemokine liver and activation- regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2. J Biol Chem 272:5846-5853.
    • (1997) J Biol Chem , vol.272 , pp. 5846-5853
    • Hieshima, K.1    Imai, T.2    Opdenakker, G.3    van Damme, J.4    Kusuda, J.5    Tei, H.6    Sakaki, Y.7    Takatsuki, K.8    Miura, R.9    Yoshie, O.10    Nomiyama, H.11
  • 24
    • 0031066574 scopus 로고    scopus 로고
    • Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3α and MIP-3β
    • Rossi DL, Vicari AP, Franz-Bacon K, McClanahan TK, Zlotnik A 1997 Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3α and MIP-3β. J Immunol 158:1033-1036.
    • (1997) J Immunol , vol.158 , pp. 1033-1036
    • Rossi, D.L.1    Vicari, A.P.2    Franz-Bacon, K.3    McClanahan, T.K.4    Zlotnik, A.5
  • 28
    • 0035861855 scopus 로고    scopus 로고
    • Human macrophage inflammatory protein-3α/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by tumor necrosis factor-α via a nonstandard NF-κB site
    • Harant H, Eldershaw SA, Lindley IJ 2001 Human macrophage inflammatory protein-3α/CCL20/LARC/Exodus/SCYA20 is transcriptionally upregulated by tumor necrosis factor-α via a nonstandard NF-κB site. FEBS Lett 509:439-445.
    • (2001) FEBS Lett , vol.509 , pp. 439-445
    • Harant, H.1    Eldershaw, S.A.2    Lindley, I.J.3
  • 29
    • 70349563430 scopus 로고    scopus 로고
    • Sengene's C, Lafontan M, Galitzky J, Bouloumié A 2009 Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators
    • Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengene's C, Lafontan M, Galitzky J, Bouloumié A 2009 Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators. Arterioscler Thromb Vasc Biol 29:1608-1614.
    • Arterioscler Thromb Vasc Biol , vol.29 , pp. 1608-1614
    • Duffaut, C.1    Zakaroff-Girard, A.2    Bourlier, V.3    Decaunes, P.4    Maumus, M.5    Chiotasso, P.6
  • 31
    • 0034923582 scopus 로고    scopus 로고
    • CC-chemokine receptor 6 and its ligand macrophage inflammatory protein 3α might be involved in the amplification of local necroinflammatory response in the liver
    • Shimizu Y, Murata H, Kashii Y, Hirano K, Kunitani H, Higuchi K, Watanabe A 2001 CC-chemokine receptor 6 and its ligand macrophage inflammatory protein 3α might be involved in the amplification of local necroinflammatory response in the liver. Hepatology 34:311-319.
    • (2001) Hepatology , vol.34 , pp. 311-319
    • Shimizu, Y.1    Murata, H.2    Kashii, Y.3    Hirano, K.4    Kunitani, H.5    Higuchi, K.6    Watanabe, A.7
  • 32
    • 0034782208 scopus 로고    scopus 로고
    • Proinflammatory cytokines induce liver and activation-regulated chemokine/macrophage inflammatory protein- 3α/CCL20 in mucosal epithelial cells through NF-κB [correction of NK-kappaB]
    • Fujiie S, Hieshima K, Izawa D, Nakayama T, Fujisawa R, Ohyanagi H, Yoshie O 2001 Proinflammatory cytokines induce liver and activation-regulated chemokine/macrophage inflammatory protein- 3α/CCL20 in mucosal epithelial cells through NF-κB [correction of NK-kappaB]. Int Immunol 13:1255-1263.
    • (2001) Int Immunol , vol.13 , pp. 1255-1263
    • Fujiie, S.1    Hieshima, K.2    Izawa, D.3    Nakayama, T.4    Fujisawa, R.5    Ohyanagi, H.6    Yoshie, O.7
  • 33
    • 0035186198 scopus 로고    scopus 로고
    • Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3 α/CCL20 by epidermal keratinocytes and its role in atopic dermatitis
    • Nakayama T, Fujisawa R, Yamada H, Horikawa T, Kawasaki H, Hieshima K, Izawa D, Fujiie S, Tezuka T, Yoshie O 2001 Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3 α/CCL20 by epidermal keratinocytes and its role in atopic dermatitis. Int Immunol 13:95-103.
    • (2001) Int Immunol , vol.13 , pp. 95-103
    • Nakayama, T.1    Fujisawa, R.2    Yamada, H.3    Horikawa, T.4    Kawasaki, H.5    Hieshima, K.6    Izawa, D.7    Fujiie, S.8    Tezuka, T.9    Yoshie, O.10
  • 34
    • 33748976352 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces expression of genes regulating immune evasion and anti-apoptosis in hepatocytes
    • Nguyen H, Sankaran S, Dandekar S 2006 Hepatitis C virus core protein induces expression of genes regulating immune evasion and anti-apoptosis in hepatocytes. Virology 354:58-68.
    • (2006) Virology , vol.354 , pp. 58-68
    • Nguyen, H.1    Sankaran, S.2    Dandekar, S.3
  • 36
    • 16844370417 scopus 로고    scopus 로고
    • FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis
    • Alikhani M, Alikhani Z, Graves DT 2005 FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. J Biol Chem 280: 12096-12102.
    • (2005) J Biol Chem , vol.280 , pp. 12096-12102
    • Alikhani, M.1    Alikhani, Z.2    Graves, D.T.3
  • 39
    • 0037428512 scopus 로고    scopus 로고
    • ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3α gene expression in Caco-2 human colonic epithelial cells
    • Kwon JH, Keates S, Simeonidis S, Grall F, Libermann TA, Keates AC 2003 ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3α gene expression in Caco-2 human colonic epithelial cells. J Biol Chem 278:875-884.
    • (2003) J Biol Chem , vol.278 , pp. 875-884
    • Kwon, J.H.1    Keates, S.2    Simeonidis, S.3    Grall, F.4    Libermann, T.A.5    Keates, A.C.6
  • 41
    • 33751533918 scopus 로고    scopus 로고
    • The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling
    • Guo S, Dunn SL, White MF 2006 The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling. Mol Endocrinol 20:3389-3399.
    • (2006) Mol Endocrinol , vol.20 , pp. 3389-3399
    • Guo, S.1    Dunn, S.L.2    White, M.F.3
  • 42
    • 0141706357 scopus 로고    scopus 로고
    • Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation
    • Matsuzaki H, Daitoku H, Hatta M, Tanaka K, Fukamizu A 2003 Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation. Proc Natl Acad Sci USA 100:11285-11290.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11285-11290
    • Matsuzaki, H.1    Daitoku, H.2    Hatta, M.3    Tanaka, K.4    Fukamizu, A.5
  • 45
    • 55649103668 scopus 로고    scopus 로고
    • Insulin resistance, inflammation, and non-alcoholic fatty liver disease
    • Tilg H, Moschen AR 2008 Insulin resistance, inflammation, and non-alcoholic fatty liver disease. Trends Endocrinol Metab 19:371-379.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 371-379
    • Tilg, H.1    Moschen, A.R.2
  • 46
    • 0036604077 scopus 로고    scopus 로고
    • Induction of macrophage-inflammatory protein-3α gene expression by TNF-dependent NF-κB activation
    • Sugita S, Kohno T, Yamamoto K, Imaizumi Y, Nakajima H, Ishimaru T, Matsuyama T 2002 Induction of macrophage-inflammatory protein-3α gene expression by TNF-dependent NF-κB activation. J Immunol 168:5621-5628.
    • (2002) J Immunol , vol.168 , pp. 5621-5628
    • Sugita, S.1    Kohno, T.2    Yamamoto, K.3    Imaizumi, Y.4    Nakajima, H.5    Ishimaru, T.6    Matsuyama, T.7
  • 47
    • 34147101043 scopus 로고    scopus 로고
    • Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor
    • Fan W, Yanase T, Morinaga H, Okabe T, Nomura M, Daitoku H, Fukamizu A, Kato S, Takayanagi R, Nawata H 2007 Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor. J Biol Chem 282:7329-7338.
    • (2007) J Biol Chem , vol.282 , pp. 7329-7338
    • Fan, W.1    Yanase, T.2    Morinaga, H.3    Okabe, T.4    Nomura, M.5    Daitoku, H.6    Fukamizu, A.7    Kato, S.8    Takayanagi, R.9    Nawata, H.10
  • 51
    • 77955906264 scopus 로고    scopus 로고
    • The nuclear factor NF-κB pathway in inflammation
    • Lawrence T 2009 The nuclear factor NF-κB pathway in inflammation. Cold Spring Harb Perspect Biol 1:a001651.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Lawrence, T.1
  • 53
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
    • Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE 2005 Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB. Nat Med 11:183-190.
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6    Shoelson, S.E.7
  • 55
    • 48349114960 scopus 로고    scopus 로고
    • Risk factors and mechanisms of non-alcoholic steatohepatitis
    • Rivera CA 2008 Risk factors and mechanisms of non-alcoholic steatohepatitis. Pathophysiology 15:109-114.
    • (2008) Pathophysiology , vol.15 , pp. 109-114
    • Rivera, C.A.1
  • 56
    • 70349972775 scopus 로고    scopus 로고
    • Apoptosis and cytokines in non-alcoholic steatohepatitis
    • Syn WK, Choi SS, Diehl AM 2009 Apoptosis and cytokines in non-alcoholic steatohepatitis. Clin Liver Dis 13:565-580.
    • (2009) Clin Liver Dis , vol.13 , pp. 565-580
    • Syn, W.K.1    Choi, S.S.2    Diehl, A.M.3
  • 57
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
    • Tilg H, Moschen AR 2010 Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology 52:1836-1846.
    • (2010) Hepatology , vol.52 , pp. 1836-1846
    • Tilg, H.1    Moschen, A.R.2
  • 60
    • 77949311823 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A review and update
    • Lewis JR, Mohanty SR 2010 Nonalcoholic fatty liver disease: a review and update. Dig Dis Sci 55:560-578
    • (2010) Dig Dis Sci , vol.55 , pp. 560-578
    • Lewis, J.R.1    Mohanty, S.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.