-
2
-
-
85017817563
-
Opium, into the arms of Morpheus
-
Ainsworth S. Opium, into the arms of Morpheus. Nurse Prescribing 2013;11(8):376-376.
-
(2013)
Nurse Prescribing
, vol.11
, Issue.8
, pp. 376-376
-
-
Ainsworth, S.1
-
3
-
-
85017795638
-
Noscapine: A Safe Cough Suppressant with Newly Discovered Effects in Treating Cancer and Stroke
-
Institute MR. Noscapine: A Safe Cough Suppressant with Newly Discovered Effects in Treating Cancer and Stroke. 2007. http://www.pcref.org/MedInsight%20-%20PCREF%20Noscapine%20Review.pdf.
-
(2007)
-
-
Institute, M.R.1
-
4
-
-
84878915943
-
Pierre-Jean Robiquet
-
Wisniak J. Pierre-Jean Robiquet. Educ Quim 2013;24(1):139-149.
-
(2013)
Educ Quim
, vol.24
, Issue.1
, pp. 139-149
-
-
Wisniak, J.1
-
5
-
-
84874204479
-
The action of opium and narcotine in malaria
-
Chopra RN, Knowles R. The action of opium and narcotine in malaria. Indian J Med Res 1930;18(1):5-13.
-
(1930)
Indian J Med Res
, vol.18
, Issue.1
, pp. 5-13
-
-
Chopra, R.N.1
Knowles, R.2
-
6
-
-
84856521159
-
PubChem Compound Database
-
CID=275196,accessed June 30
-
National Center for Biotechnology Information. PubChem Compound Database; CID=275196, https://pubchem.ncbi.nlm.nih.gov/compound/275196 (accessed June 30, 2015).
-
(2015)
-
-
-
7
-
-
0003601534
-
The Merck Index
-
9th ed. Rahway, New Jersey: Merck & Co., Inc.
-
The Merck Index. 9th ed. Rahway, New Jersey: Merck & Co., Inc., 1976., p. 872.
-
(1976)
, pp. 872
-
-
-
8
-
-
84878934471
-
Note sur la Narcotine
-
Robiquet P. Note sur la Narcotine. J Pharm 1831;17:637-643.
-
(1831)
J Pharm
, vol.17
, pp. 637-643
-
-
Robiquet, P.1
-
9
-
-
84861878374
-
Characterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy
-
Dang TTT, Facchini PJ. Characterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy. Plant Physiol 2012;159(2):618-631.
-
(2012)
Plant Physiol
, vol.159
, Issue.2
, pp. 618-631
-
-
Dang, T.T.T.1
Facchini, P.J.2
-
10
-
-
84893122130
-
CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy
-
Dang TT, Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. J Biol Chem 2014;289(4):2013-2026.
-
(2014)
J Biol Chem
, vol.289
, Issue.4
, pp. 2013-2026
-
-
Dang, T.T.1
Facchini, P.J.2
-
11
-
-
84891011601
-
Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy
-
Dang TT, Facchini PJ. Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy. FEBS Lett 2014;588(1):198-204.
-
(2014)
FEBS Lett
, vol.588
, Issue.1
, pp. 198-204
-
-
Dang, T.T.1
Facchini, P.J.2
-
12
-
-
84922715776
-
Acetylation serves as a protective group in noscapine biosynthesis in opium poppy
-
Dang TT, Chen X, Facchini PJ. Acetylation serves as a protective group in noscapine biosynthesis in opium poppy. Nat Chem Biol 2015;11(2):104-106.
-
(2015)
Nat Chem Biol
, vol.11
, Issue.2
, pp. 104-106
-
-
Dang, T.T.1
Chen, X.2
Facchini, P.J.3
-
13
-
-
84862983375
-
A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine
-
Winzer T, Gazda V, He Z, Kaminski F, Kern M, Larson TR, Li Y, Meade F, Teodor R, Vaistij FE, Walker C, Bowser TA, Graham IA. A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science 2012;336(6089):1704-1708.
-
(2012)
Science
, vol.336
, Issue.6089
, pp. 1704-1708
-
-
Winzer, T.1
Gazda, V.2
He, Z.3
Kaminski, F.4
Kern, M.5
Larson, T.R.6
Li, Y.7
Meade, F.8
Teodor, R.9
Vaistij, F.E.10
Walker, C.11
Bowser, T.A.12
Graham, I.A.13
-
14
-
-
84892369559
-
Short-chain dehydrogenase/reductase catalyzing the final step of noscapine biosynthesis is localized to laticifers in opium poppy
-
Chen X, Facchini PJ. Short-chain dehydrogenase/reductase catalyzing the final step of noscapine biosynthesis is localized to laticifers in opium poppy. Plant J 2014;77(2):173-184.
-
(2014)
Plant J
, vol.77
, Issue.2
, pp. 173-184
-
-
Chen, X.1
Facchini, P.J.2
-
15
-
-
85017795638
-
Noscapine a safe cough suppressant with newly discovered effects in treating cancer and stroke
-
Institute MR. Noscapine a safe cough suppressant with newly discovered effects in treating cancer and stroke. 2007.
-
(2007)
-
-
Institute, M.R.1
-
16
-
-
0033860106
-
Codeine analgesia is due to codeine-6-glucuronide, not morphine
-
Vree TB, vanDongen RT, Koopman-Kimenai PM. Codeine analgesia is due to codeine-6-glucuronide, not morphine. Int J Clin Pract 2000;54(6):395-398.
-
(2000)
Int J Clin Pract
, vol.54
, Issue.6
, pp. 395-398
-
-
Vree, T.B.1
van Dongen, R.T.2
Koopman-Kimenai, P.M.3
-
17
-
-
84863649956
-
Management of opioid analgesic overdose
-
Boyer E. Management of opioid analgesic overdose. N Engl J Med 2012;367:146-155.
-
(2012)
N Engl J Med
, vol.367
, pp. 146-155
-
-
Boyer, E.1
-
18
-
-
0030265265
-
Role of Opioidergic and Serotonergic Mechanisms in Cough and Antitussives
-
Kamei, J. Role of Opioidergic and Serotonergic Mechanisms in Cough and Antitussives. Pulmonary Pharmacology 1996;9:349-356.
-
(1996)
Pulmonary Pharmacology
, vol.9
, pp. 349-356
-
-
Kamei, J.1
-
19
-
-
85017799100
-
Noscapine antagonizes vasoconstrictor action of bradykinin in isolated human umbilical artery
-
Mahmoudian M, Aboutaleb N, Beiranvand F, Moazzam A-A, Shafiei M. Noscapine antagonizes vasoconstrictor action of bradykinin in isolated human umbilical artery. Med J Islam Repub Iran 2011;25(2):82-86.
-
(2011)
Med J Islam Repub Iran
, vol.25
, Issue.2
, pp. 82-86
-
-
Mahmoudian, M.1
Aboutaleb, N.2
Beiranvand, F.3
Moazzam, A.-A.4
Shafiei, M.5
-
20
-
-
28444493591
-
Noscapine suppresses angiotensin converting enzyme inhibitors-induced cough
-
Mooraki A, Jenabi A, Jabbari M, Zolfaghari MI, Javanmardi SZ, Mahmoudian M, Bastani B. Noscapine suppresses angiotensin converting enzyme inhibitors-induced cough. Nephrology 2005;10(4):348-350.
-
(2005)
Nephrology
, vol.10
, Issue.4
, pp. 348-350
-
-
Mooraki, A.1
Jenabi, A.2
Jabbari, M.3
Zolfaghari, M.I.4
Javanmardi, S.Z.5
Mahmoudian, M.6
Bastani, B.7
-
21
-
-
0345598132
-
A preliminary report on the application of noscapine in the treatment of stroke
-
Mahmoudian M, Mehrpour M, Benaissa F, Siadatpour Z. A preliminary report on the application of noscapine in the treatment of stroke. Eur J Clin Pharmacol 2003;59(8-9):579-581.
-
(2003)
Eur J Clin Pharmacol
, vol.59
, Issue.8-9
, pp. 579-581
-
-
Mahmoudian, M.1
Mehrpour, M.2
Benaissa, F.3
Siadatpour, Z.4
-
22
-
-
0026567697
-
Epidemiology of stroke
-
Bonita R. Epidemiology of stroke. Lancet 1992;339(8789):342-344.
-
(1992)
Lancet
, vol.339
, Issue.8789
, pp. 342-344
-
-
Bonita, R.1
-
23
-
-
0026544583
-
Bradykinin and neuronal injury
-
Francel PC. Bradykinin and neuronal injury. J Neurotrauma 1992;9(Suppl 1):S27-S45.
-
(1992)
J Neurotrauma
, vol.9
, pp. S27-S45
-
-
Francel, P.C.1
-
24
-
-
84898815178
-
The protective activity of noscapine on renal ischemia-reperfusion injury in male Wistar rat
-
Khanmoradi M, Ali Mard S, Aboutaleb N, Nobakht M, Mahmoudian M. The protective activity of noscapine on renal ischemia-reperfusion injury in male Wistar rat. Iran J Basic Med Sci 2014;17(4):244-249.
-
(2014)
Iran J Basic Med Sci
, vol.17
, Issue.4
, pp. 244-249
-
-
Khanmoradi, M.1
Ali Mard, S.2
Aboutaleb, N.3
Nobakht, M.4
Mahmoudian, M.5
-
25
-
-
0033928547
-
Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses
-
Ke Y, Ye K, Grossniklaus HE, Archer DR, Joshi HC, Kapp JA. Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses. Cancer Immunol Immunother 2000;49(4-5):217-225.
-
(2000)
Cancer Immunol Immunother
, vol.49
, Issue.4-5
, pp. 217-225
-
-
Ke, Y.1
Ye, K.2
Grossniklaus, H.E.3
Archer, D.R.4
Joshi, H.C.5
Kapp, J.A.6
-
26
-
-
0032539565
-
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells
-
Ye K, Ke Y, Keshava N, Shanks J, Kapp JA, Tekmal RR, Petros J, Joshi HC. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells. Proc Natl Acad Sci USA 1998;95(4):1601-1606.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.4
, pp. 1601-1606
-
-
Ye, K.1
Ke, Y.2
Keshava, N.3
Shanks, J.4
Kapp, J.A.5
Tekmal, R.R.6
Petros, J.7
Joshi, H.C.8
-
27
-
-
0037053409
-
Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint
-
Zhou J, Panda D, Landen JW, Wilson L, Joshi HC. Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint. J Biol Chem 2002;277(19):17200-17208.
-
(2002)
J Biol Chem
, vol.277
, Issue.19
, pp. 17200-17208
-
-
Zhou, J.1
Panda, D.2
Landen, J.W.3
Wilson, L.4
Joshi, H.C.5
-
28
-
-
33749555016
-
Treatment of hormone-refractory breast cancer: Apoptosis and regression of human tumors implanted in mice
-
Aneja R, Zhou J, Zhou B, Chandra R, Joshi HC. Treatment of hormone-refractory breast cancer: Apoptosis and regression of human tumors implanted in mice. Mol Cancer Ther 2006;5(9):2366-2377.
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.9
, pp. 2366-2377
-
-
Aneja, R.1
Zhou, J.2
Zhou, B.3
Chandra, R.4
Joshi, H.C.5
-
29
-
-
44249102976
-
Thymoma, myasthenia gravis, and other paraneoplastic syndromes
-
Tormoehlen LM, Pascuzzi RM. Thymoma, myasthenia gravis, and other paraneoplastic syndromes. Hematol Oncol Clin North Am 2008;22(3):509-526.
-
(2008)
Hematol Oncol Clin North Am
, vol.22
, Issue.3
, pp. 509-526
-
-
Tormoehlen, L.M.1
Pascuzzi, R.M.2
-
30
-
-
0032539565
-
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells
-
Ye K, Ke Y, Keshava N, Shanks J, Kapp JA, Tekmal RR, Petros J, Joshi HC. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells. Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1601-1606.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.4
, pp. 1601-1606
-
-
Ye, K.1
Ke, Y.2
Keshava, N.3
Shanks, J.4
Kapp, J.A.5
Tekmal, R.R.6
Petros, J.7
Joshi, H.C.8
-
31
-
-
0037131307
-
Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine
-
Zhou J, Gupta K, Yao J, Ye K, Panda D, Giannakakou P, Joshi HC. Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. J Biol Chem 2002;277(42):39777-39785.
-
(2002)
J Biol Chem
, vol.277
, Issue.42
, pp. 39777-39785
-
-
Zhou, J.1
Gupta, K.2
Yao, J.3
Ye, K.4
Panda, D.5
Giannakakou, P.6
Joshi, H.C.7
-
33
-
-
84930415849
-
Noscapine increases the sensitivity of drug-resistant ovarian cancer cell line SKOV3/DDP to cisplatin by regulating cell cycle and activating apoptotic pathways
-
Shen W, Liang B, Yin J, Li X, Cheng J. Noscapine increases the sensitivity of drug-resistant ovarian cancer cell line SKOV3/DDP to cisplatin by regulating cell cycle and activating apoptotic pathways. Cell Biochem Biophys 2014.
-
(2014)
Cell Biochem Biophys
-
-
Shen, W.1
Liang, B.2
Yin, J.3
Li, X.4
Cheng, J.5
-
35
-
-
79953201844
-
Noscapine sensitizes chemoresistant ovarian cancer cells to cisplatin through inhibition of HIF-1alpha
-
Su W, Huang L, Ao Q, Zhang Q, Tian X, Fang Y, Lu Y. Noscapine sensitizes chemoresistant ovarian cancer cells to cisplatin through inhibition of HIF-1alpha. Cancer Lett 2011;305(1):94-99.
-
(2011)
Cancer Lett
, vol.305
, Issue.1
, pp. 94-99
-
-
Su, W.1
Huang, L.2
Ao, Q.3
Zhang, Q.4
Tian, X.5
Fang, Y.6
Lu, Y.7
-
36
-
-
4143090412
-
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth
-
Landen JW, Hau V, Wang M, Davis T, Ciliax B, Wainer BH, VanMeir EG, Glass JD, Joshi HC, Archer DR. Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth. Clin Cancer Res 2004;10(15):5187-5201.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.15
, pp. 5187-5201
-
-
Landen, J.W.1
Hau, V.2
Wang, M.3
Davis, T.4
Ciliax, B.5
Wainer, B.H.6
Van Meir, E.G.7
Glass, J.D.8
Joshi, H.C.9
Archer, D.R.10
-
37
-
-
84876701208
-
Poly (ethylene)-glycol conjugated solid lipid nanoparticles of noscapine improve biological half-life, brain delivery and efficacy in glioblastoma cells
-
Madan J, Pandey RS, Jain V, Katare OP, Chandra R, Katyal A. Poly (ethylene)-glycol conjugated solid lipid nanoparticles of noscapine improve biological half-life, brain delivery and efficacy in glioblastoma cells. Nanomedicine 2013;9(4):492-503.
-
(2013)
Nanomedicine
, vol.9
, Issue.4
, pp. 492-503
-
-
Madan, J.1
Pandey, R.S.2
Jain, V.3
Katare, O.P.4
Chandra, R.5
Katyal, A.6
-
38
-
-
33747197540
-
Synthesis and in vitro cytotoxicity of haloderivatives of noscapine
-
Verma AK, Bansal S, Singh J, Tiwari RK, Kasi Sankar V, Tandon V, Chandra R. Synthesis and in vitro cytotoxicity of haloderivatives of noscapine. Bioorg Med Chem 2006;14(19):6733-6736.
-
(2006)
Bioorg Med Chem
, vol.14
, Issue.19
, pp. 6733-6736
-
-
Verma, A.K.1
Bansal, S.2
Singh, J.3
Tiwari, R.K.4
Kasi Sankar, V.5
Tandon, V.6
Chandra, R.7
-
39
-
-
33646039750
-
Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro
-
Altinoz MA, Bilir A, Del Maestro RF, Tuna S, Ozcan E, Gedikoglu G. Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro. Surg Neurol 2006;65:478-485.
-
(2006)
Surg Neurol
, vol.65
, pp. 478-485
-
-
Altinoz, M.B.A.1
Del Maestro, R.F.2
Tuna, S.3
Ozcan, E.4
Gedikoglu, G.5
-
40
-
-
84881441534
-
Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth
-
Qi Q, Liu X, Li S, Joshi HC, Ye K. Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth. Acta Pharmacol Sin 2013;34(7):930-938.
-
(2013)
Acta Pharmacol Sin
, vol.34
, Issue.7
, pp. 930-938
-
-
Qi, Q.1
Liu, X.2
Li, S.3
Joshi, H.C.4
Ye, K.5
-
41
-
-
80054006821
-
Noscapine inhibits tumor growth in TMZ-resistant gliomas
-
Jhaveri N, Cho H, Torres S, Wang W, Schonthal AH, Petasis NA, Louie SG, Hofman FM, Chen TC. Noscapine inhibits tumor growth in TMZ-resistant gliomas. Cancer Lett 2011;312(2):245-252.
-
(2011)
Cancer Lett
, vol.312
, Issue.2
, pp. 245-252
-
-
Jhaveri, N.1
Cho, H.2
Torres, S.3
Wang, W.4
Schonthal, A.H.5
Petasis, N.A.6
Louie, S.G.7
Hofman, F.M.8
Chen, T.C.9
-
42
-
-
79958021833
-
Decreased therapeutic effects of noscapine combined with imatinib mesylate on human glioblastoma in vitro and the effect of midkine
-
Erguven M, Bilir A, Yazihan N, Ermis E, Sabanci A, Aktas E, Aras Y, Alpman V. Decreased therapeutic effects of noscapine combined with imatinib mesylate on human glioblastoma in vitro and the effect of midkine. Cancer Cell Int 2011;11(1):18.
-
(2011)
Cancer Cell Int
, vol.11
, Issue.1
, pp. 18
-
-
Erguven, M.1
Bilir, A.2
Yazihan, N.3
Ermis, E.4
Sabanci, A.5
Aktas, E.6
Aras, Y.7
Alpman, V.8
-
43
-
-
47149101512
-
Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors
-
Newcomb EW, Lukyanov Y, Alonso-Basanta M, Esencay M, Smirnova I, Schnee T, Shao Y, Devitt ML, Zagzag D, McBride W, Formenti SC. Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors. Int J Radiat Oncol Biol Phys 2008;71(5):1477-1484.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, Issue.5
, pp. 1477-1484
-
-
Newcomb, E.W.1
Lukyanov, Y.2
Alonso-Basanta, M.3
Esencay, M.4
Smirnova, I.5
Schnee, T.6
Shao, Y.7
Devitt, M.L.8
Zagzag, D.9
McBride, W.10
Formenti, S.C.11
-
44
-
-
53149119507
-
Antitumor activity of noscapine in human non-small cell lung cancer xenograft model
-
Jackson T, Chougule MB, Ichite N, Patlolla RR, Singh M. Antitumor activity of noscapine in human non-small cell lung cancer xenograft model. Cancer Chemother Pharmacol 2008;63(1):117-126.
-
(2008)
Cancer Chemother Pharmacol
, vol.63
, Issue.1
, pp. 117-126
-
-
Jackson, T.1
Chougule, M.B.2
Ichite, N.3
Patlolla, R.R.4
Singh, M.5
-
45
-
-
84864380566
-
Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53
-
Li S, He J, Li S, Cao G, Tang S, Tong Q, Joshi HC. Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53. PLoS One 2012;7(7):e40076.
-
(2012)
PLoS One
, vol.7
, Issue.7
, pp. e40076
-
-
Li, S.1
He, J.2
Li, S.3
Cao, G.4
Tang, S.5
Tong, Q.6
Joshi, H.C.7
-
46
-
-
79851512201
-
Anticancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer
-
Chougule M, Patel AR, Sachdeva P, Jackson T, Singh M. Anticancer activity of noscapine, an opioid alkaloid in combination with cisplatin in human non-small cell lung cancer. Lung Cancer 2011;71(3):271-282.
-
(2011)
Lung Cancer
, vol.71
, Issue.3
, pp. 271-282
-
-
Chougule, M.1
Patel, A.R.2
Sachdeva, P.3
Jackson, T.4
Singh, M.5
-
47
-
-
81055125711
-
Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer
-
Chougule MB, Patel A, Sachdeva P, Jackson T, Singh M. Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer. PLoS One 2011;6(11):e27394.
-
(2011)
PLoS One
, vol.6
, Issue.11
, pp. e27394
-
-
Chougule, M.B.1
Patel, A.2
Sachdeva, P.3
Jackson, T.4
Singh, M.5
-
48
-
-
84875076771
-
Sterically stabilized gelatin microassemblies of noscapine enhance cytotoxicity, apoptosis and drug delivery in lung cancer cells
-
Madan J, Pandey RS, Jain UK, Katare OP, Aneja R, Katyal A. Sterically stabilized gelatin microassemblies of noscapine enhance cytotoxicity, apoptosis and drug delivery in lung cancer cells. Colloids Surf B Biointerfaces 2013;107:235-244.
-
(2013)
Colloids Surf B Biointerfaces
, vol.107
, pp. 235-244
-
-
Madan, J.1
Pandey, R.S.2
Jain, U.K.3
Katare, O.P.4
Aneja, R.5
Katyal, A.6
-
49
-
-
79953792744
-
Noscapine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo
-
Liu M, Luo XJ, Liao F, Lei XF, Dong WG. Noscapine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo. Cancer Chemother Pharmacol 2011;67(3):605-612.
-
(2011)
Cancer Chemother Pharmacol
, vol.67
, Issue.3
, pp. 605-612
-
-
Liu, M.1
Luo, X.J.2
Liao, F.3
Lei, X.F.4
Dong, W.G.5
-
50
-
-
34248577475
-
p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells
-
Aneja R, Ghaleb AM, Zhou J, Yang VW, Joshi HC. p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells. Cancer Res 2007;67(8):3862-3870.
-
(2007)
Cancer Res
, vol.67
, Issue.8
, pp. 3862-3870
-
-
Aneja, R.1
Ghaleb, A.M.2
Zhou, J.3
Yang, V.W.4
Joshi, H.C.5
-
51
-
-
84860700118
-
Noscapine induces mitochondria-mediated apoptosis in human colon cancer cells in vivo and in vitro
-
Yang ZR, Liu M, Peng XL, Lei XF, Zhang JX, Dong WG. Noscapine induces mitochondria-mediated apoptosis in human colon cancer cells in vivo and in vitro. Biochem Biophys Res Commun 2012;421(3):627-633.
-
(2012)
Biochem Biophys Res Commun
, vol.421
, Issue.3
, pp. 627-633
-
-
Yang, Z.R.1
Liu, M.2
Peng, X.L.3
Lei, X.F.4
Zhang, J.X.5
Dong, W.G.6
-
52
-
-
58149154969
-
Noscapine inhibits human prostate cancer progression and metastasis in a mouse model
-
Barken I, Geller J, Rogosnitzky M. Noscapine inhibits human prostate cancer progression and metastasis in a mouse model. Anticancer Res 2008;28(6a):3701-3704.
-
(2008)
Anticancer Res
, vol.28
, Issue.6A
, pp. 3701-3704
-
-
Barken, I.1
Geller, J.2
Rogosnitzky, M.3
-
53
-
-
78751581881
-
Synergistic antimicrotubule therapy for prostate cancer
-
Pannu V, Karna P, Sajja HK, Shukla D, Aneja R. Synergistic antimicrotubule therapy for prostate cancer. Biochem Pharmacol 2011;81(4):478-487.
-
(2011)
Biochem Pharmacol
, vol.81
, Issue.4
, pp. 478-487
-
-
Pannu, V.1
Karna, P.2
Sajja, H.K.3
Shukla, D.4
Aneja, R.5
-
54
-
-
79952637468
-
Antitumor activity of noscapine in combination with doxorubicin in triple negative breast cancer
-
Chougule MB, Patel AR, Jackson T, Singh M. Antitumor activity of noscapine in combination with doxorubicin in triple negative breast cancer. PLoS One 2011;6(3):e17733.
-
(2011)
PLoS One
, vol.6
, Issue.3
, pp. e17733
-
-
Chougule, M.B.1
Patel, A.R.2
Jackson, T.3
Singh, M.4
-
55
-
-
84901608239
-
Enhanced noscapine delivery using estrogen-receptor-targeted nanoparticles for breast cancer therapy
-
Madan J, Gundala SR, Kasetti Y, Bharatam PV, Aneja R, Katyal A, Jain UK. Enhanced noscapine delivery using estrogen-receptor-targeted nanoparticles for breast cancer therapy. Anticancer Drugs 2014;25(6):704-716.
-
(2014)
Anticancer Drugs
, vol.25
, Issue.6
, pp. 704-716
-
-
Madan, J.1
Gundala, S.R.2
Kasetti, Y.3
Bharatam, P.V.4
Aneja, R.5
Katyal, A.6
Jain, U.K.7
-
56
-
-
0013586083
-
Inhibitory effects of noscapine on dopamine biosynthesis in PC12 cells
-
Shin JS, Lee SS, Lee MK. Inhibitory effects of noscapine on dopamine biosynthesis in PC12 cells. Arch Pharm Res 1997;20(5):510-512.
-
(1997)
Arch Pharm Res
, vol.20
, Issue.5
, pp. 510-512
-
-
Shin, J.S.1
Lee, S.S.2
Lee, M.K.3
-
57
-
-
77953449917
-
Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats
-
Priyadarshani A, Chuttani K, Mittal G, Bhatnagar A. Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats. J Ovarian Res 2010;3:10.
-
(2010)
J Ovarian Res
, vol.3
, pp. 10
-
-
Priyadarshani, A.1
Chuttani, K.2
Mittal, G.3
Bhatnagar, A.4
-
58
-
-
84876184565
-
Do viruses require the cytoskeleton?
-
Matthews JD, Morgan R, Sleigher C, Frey TK. Do viruses require the cytoskeleton? Virol J 2013;10(121):121-125.
-
(2013)
Virol J
, vol.10
, Issue.121
, pp. 121-125
-
-
Matthews, J.D.1
Morgan, R.2
Sleigher, C.3
Frey, T.K.4
-
59
-
-
0019991766
-
Pharmacokinetic properties of noscapine
-
Dahlstrom B, Mellstrand T, Lofdahl CG, Johansson M. Pharmacokinetic properties of noscapine. Eur J Clin Pharmacol 1982;22(6):535-539.
-
(1982)
Eur J Clin Pharmacol
, vol.22
, Issue.6
, pp. 535-539
-
-
Dahlstrom, B.1
Mellstrand, T.2
Lofdahl, C.G.3
Johansson, M.4
-
60
-
-
0025010475
-
Pharmacokinetics of oral noscapine
-
Karlsson MO, Dahlstrom B, Eckernas SA, Johansson M, Alm AT. Pharmacokinetics of oral noscapine. Eur J Clin Pharmacol 1990;39(3):275-279.
-
(1990)
Eur J Clin Pharmacol
, vol.39
, Issue.3
, pp. 275-279
-
-
Karlsson, M.O.1
Dahlstrom, B.2
Eckernas, S.A.3
Johansson, M.4
Alm, A.T.5
-
61
-
-
34548574659
-
Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent
-
Aneja R, Dhiman N, Idnani J, Awasthi A, Arora SK, Chandra R, Joshi HC. Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent. Cancer Chemother Pharmacol 2007;60(6):831-839.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, Issue.6
, pp. 831-839
-
-
Aneja, R.1
Dhiman, N.2
Idnani, J.3
Awasthi, A.4
Arora, S.K.5
Chandra, R.6
Joshi, H.C.7
-
62
-
-
75549086206
-
Inclusion complexes of noscapine in beta-cyclodextrin offer better solubility and improved pharmacokinetics
-
Madan J, Dhiman N, Parmar VK, Sardana S, Bharatam PV, Aneja R, Chandra R, Katyal A. Inclusion complexes of noscapine in beta-cyclodextrin offer better solubility and improved pharmacokinetics. Cancer Chemother Pharmacol 2010;65(3):537-548.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, Issue.3
, pp. 537-548
-
-
Madan, J.1
Dhiman, N.2
Parmar, V.K.3
Sardana, S.4
Bharatam, P.V.5
Aneja, R.6
Chandra, R.7
Katyal, A.8
-
63
-
-
84902298182
-
Epithelial transport of noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: Implications for intestinal absorption
-
Chougule MB, Patel AR, Patlolla R, Jackson T, Singh M. Epithelial transport of noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: Implications for intestinal absorption. J Drug Target 2014;22(6):498-508.
-
(2014)
J Drug Target
, vol.22
, Issue.6
, pp. 498-508
-
-
Chougule, M.B.1
Patel, A.R.2
Patlolla, R.3
Jackson, T.4
Singh, M.5
-
64
-
-
84867824844
-
Metabolic map and bioactivation of the anti-tumour drug noscapine
-
Fang ZZ, Krausz KW, Li F, Cheng J, Tanaka N, Gonzalez FJ. Metabolic map and bioactivation of the anti-tumour drug noscapine. Brit J Pharmacol 2012;167(6):1271-1286.
-
(2012)
Brit J Pharmacol
, vol.167
, Issue.6
, pp. 1271-1286
-
-
Fang, Z.Z.1
Krausz, K.W.2
Li, F.3
Cheng, J.4
Tanaka, N.5
Gonzalez, F.J.6
-
65
-
-
0035861653
-
Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis
-
Ye K, Zhou J, Landen JW, Bradbury EM, Joshi HC. Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis. J Biol Chem 2001;276(50):46697-46700.
-
(2001)
J Biol Chem
, vol.276
, Issue.50
, pp. 46697-46700
-
-
Ye, K.1
Zhou, J.2
Landen, J.W.3
Bradbury, E.M.4
Joshi, H.C.5
-
66
-
-
77951049854
-
Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway
-
Sung B, Ahn KS, Aggarwal BB. Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway. Cancer Res 2010;70(8):3259-3268.
-
(2010)
Cancer Res
, vol.70
, Issue.8
, pp. 3259-3268
-
-
Sung, B.1
Ahn, K.S.2
Aggarwal, B.B.3
-
67
-
-
84896284555
-
Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A
-
Kach J, Sandbo N, La J, Denner D, Reed EB, Akimova O, Koltsova S, Orlov SN, Dulin NO. Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A. J Biol Chem 2014;289(11):7505-7513.
-
(2014)
J Biol Chem
, vol.289
, Issue.11
, pp. 7505-7513
-
-
Kach, J.1
Sandbo, N.2
La, J.3
Denner, D.4
Reed, E.B.5
Akimova, O.6
Koltsova, S.7
Orlov, S.N.8
Dulin, N.O.9
-
68
-
-
0008567014
-
Toxicity after large doses of noscapine
-
Lasagna L, Owens AH, Jr., Shnider BI, Gold GL. Toxicity after large doses of noscapine. Cancer Chemother Rep 1961;15:33-34.
-
(1961)
Cancer Chemother Rep
, vol.15
, pp. 33-34
-
-
Lasagna, L.1
Owens, A.H.2
Shnider, B.I.3
Gold, G.L.4
-
69
-
-
38849140372
-
Noscapine may increase the effect of warfarin
-
Ohlsson S, Holm L, Myrberg O, Sundström A, Yue Q-Y. Noscapine may increase the effect of warfarin. Brit J Clin Pharmacol 2008;65(2):277-278.
-
(2008)
Brit J Clin Pharmacol
, vol.65
, Issue.2
, pp. 277-278
-
-
Ohlsson, S.1
Holm, L.2
Myrberg, O.3
Sundström, A.4
Yue, Q.-Y.5
-
70
-
-
75149152466
-
Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction
-
Fang Z-Z, Zhang Y-Y, Ge G-B, Huo H, Liang S-C, Yang L. Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction. Brit J Clin Pharmacol 2010;69(2):193-199.
-
(2010)
Brit J Clin Pharmacol
, vol.69
, Issue.2
, pp. 193-199
-
-
Fang, Z.-Z.1
Zhang, Y.-Y.2
Ge, G.-B.3
Huo, H.4
Liang, S.-C.5
Yang, L.6
-
71
-
-
84888619257
-
Characterization of inhibition kinetics of (S)-warfarin hydroxylation by noscapine: implications in warfarin therapy
-
Zhang N, Seguin RP, Kunze KL, Zhang YY, Jeong H. Characterization of inhibition kinetics of (S)-warfarin hydroxylation by noscapine: implications in warfarin therapy. Drug Metab Dispos 2013;41(12):2114-2123.
-
(2013)
Drug Metab Dispos
, vol.41
, Issue.12
, pp. 2114-2123
-
-
Zhang, N.1
Seguin, R.P.2
Kunze, K.L.3
Zhang, Y.Y.4
Jeong, H.5
-
72
-
-
84901022581
-
Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and death
-
Ogden A, Cheng A, Rida PC, Pannu V, Osan R, Clewley R, Aneja R. Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and death. Cell Death Dis 2014;5:e1204.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1204
-
-
Ogden, A.1
Cheng, A.2
Rida, P.C.3
Pannu, V.4
Osan, R.5
Clewley, R.6
Aneja, R.7
-
73
-
-
84908539510
-
Taking aim at a dynamic target: Noscapinoids as microtubule-targeted cancer therapeutics
-
Lopus M, Naik PK. Taking aim at a dynamic target: Noscapinoids as microtubule-targeted cancer therapeutics. Pharmacol Rep 2015;67(1):56-62.
-
(2015)
Pharmacol Rep
, vol.67
, Issue.1
, pp. 56-62
-
-
Lopus, M.1
Naik, P.K.2
-
74
-
-
80052610402
-
Determination of noscapine's localization and interaction with the tubulin-alpha/beta heterodimer
-
Alisaraie L, Tuszynski JA. Determination of noscapine's localization and interaction with the tubulin-alpha/beta heterodimer. Chem Biol Drug Des 2011;78(4):535-546.
-
(2011)
Chem Biol Drug Des
, vol.78
, Issue.4
, pp. 535-546
-
-
Alisaraie, L.1
Tuszynski, J.A.2
-
75
-
-
77953311754
-
Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent
-
Karna P, Zughaier S, Pannu V, Simmons R, Narayan S, Aneja R. Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent. J Biol Chem 2010;285(24):18737-18748.
-
(2010)
J Biol Chem
, vol.285
, Issue.24
, pp. 18737-18748
-
-
Karna, P.1
Zughaier, S.2
Pannu, V.3
Simmons, R.4
Narayan, S.5
Aneja, R.6
-
76
-
-
84864874569
-
Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: A novel chemotherapeutic approach
-
Pannu V, Rida PC, Ogden A, Clewley R, Cheng A, Karna P, Lopus M, Mishra RC, Zhou J, Aneja R. Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: A novel chemotherapeutic approach. Cell Death Dis 2012;3:e346.
-
(2012)
Cell Death Dis
, vol.3
, pp. e346
-
-
Pannu, V.1
Rida, P.C.2
Ogden, A.3
Clewley, R.4
Cheng, A.5
Karna, P.6
Lopus, M.7
Mishra, R.C.8
Zhou, J.9
Aneja, R.10
-
77
-
-
84914174024
-
Cyclodextrin complexes of reduced bromonoscapine in guar gum microspheres enhance colonic drug delivery
-
Madan J, Gundala SR, Baruah B, Nagaraju M, Yates C, Turner T, Rangari V, Hamelberg D, Reid MD, Aneja R. Cyclodextrin complexes of reduced bromonoscapine in guar gum microspheres enhance colonic drug delivery. Mol Pharm 2014;11(12):4339-4349.
-
(2014)
Mol Pharm
, vol.11
, Issue.12
, pp. 4339-4349
-
-
Madan, J.1
Gundala, S.R.2
Baruah, B.3
Nagaraju, M.4
Yates, C.5
Turner, T.6
Rangari, V.7
Hamelberg, D.8
Reid, M.D.9
Aneja, R.10
-
78
-
-
79955832918
-
Molecular modeling and competition binding study of Br-noscapine and colchicine provides insight into noscapinoid-tubulin binding site
-
Naik PK, Santoshi S, Rai A, Joshi HC. Molecular modeling and competition binding study of Br-noscapine and colchicine provides insight into noscapinoid-tubulin binding site. J Mol Graph Model 2011;29(7):947-955.
-
(2011)
J Mol Graph Model
, vol.29
, Issue.7
, pp. 947-955
-
-
Naik, P.K.1
Santoshi, S.2
Rai, A.3
Joshi, H.C.4
-
79
-
-
77949433802
-
Potent anti-inflammatory activity of novel microtubule-modulating brominated noscapine analogs
-
Zughaier S, Karna P, Stephens D, Aneja R. Potent anti-inflammatory activity of novel microtubule-modulating brominated noscapine analogs. PLoS One 2010;5(2):e9165.
-
(2010)
PLoS One
, vol.5
, Issue.2
, pp. e9165
-
-
Zughaier, S.1
Karna, P.2
Stephens, D.3
Aneja, R.4
-
80
-
-
84897024163
-
The synthesis and biological evaluation of multifunctionalised derivatives of noscapine as cytotoxic agents
-
Debono AJ, Mistry SJ, Xie J, Muthiah D, Phillips J, Ventura S, Callaghan R, Pouton CW, Capuano B, Scammells PJ. The synthesis and biological evaluation of multifunctionalised derivatives of noscapine as cytotoxic agents. ChemMedChem 2014;9(2):399-410.
-
(2014)
ChemMedChem
, vol.9
, Issue.2
, pp. 399-410
-
-
Debono, A.J.1
Mistry, S.J.2
Xie, J.3
Muthiah, D.4
Phillips, J.5
Ventura, S.6
Callaghan, R.7
Pouton, C.W.8
Capuano, B.9
Scammells, P.J.10
-
81
-
-
0037379660
-
Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation
-
Zhou J, Gupta K, Aggarwal S, Aneja R, Chandra R, Panda D, Joshi HC. Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation. Mol Pharmacol 2003;63(4):799-807.
-
(2003)
Mol Pharmacol
, vol.63
, Issue.4
, pp. 799-807
-
-
Zhou, J.1
Gupta, K.2
Aggarwal, S.3
Aneja, R.4
Chandra, R.5
Panda, D.6
Joshi, H.C.7
-
82
-
-
33745933637
-
Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death
-
Aneja R, Vangapandu SN, Lopus M, Viswesarappa VG, Dhiman N, Verma A, Chandra R, Panda D, Joshi HC. Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death. Biochem Pharmacol 2006;72(4):415-426.
-
(2006)
Biochem Pharmacol
, vol.72
, Issue.4
, pp. 415-426
-
-
Aneja, R.1
Vangapandu, S.N.2
Lopus, M.3
Viswesarappa, V.G.4
Dhiman, N.5
Verma, A.6
Chandra, R.7
Panda, D.8
Joshi, H.C.9
-
83
-
-
77952564020
-
A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells
-
Aneja R, Miyagi T, Karna P, Ezell T, Shukla D, Vij Gupta M, Yates C, Chinni SR, Zhau H, Chung LW, Joshi HC. A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells. Eur J Cancer 2010;46(9):1668-1678.
-
(2010)
Eur J Cancer
, vol.46
, Issue.9
, pp. 1668-1678
-
-
Aneja, R.1
Miyagi, T.2
Karna, P.3
Ezell, T.4
Shukla, D.5
Vij Gupta, M.6
Yates, C.7
Chinni, S.R.8
Zhau, H.9
Chung, L.W.10
Joshi, H.C.11
-
84
-
-
84860717951
-
Molecular cycloencapsulation augments solubility and improves therapeutic index of brominated noscapine in prostate cancer cells
-
Madan J, Baruah B, Nagaraju M, Abdalla MO, Yates C, Turner T, Rangari V, Hamelberg D, Aneja R. Molecular cycloencapsulation augments solubility and improves therapeutic index of brominated noscapine in prostate cancer cells. Mol Pharm 2012;9(5):1470-1480.
-
(2012)
Mol Pharm
, vol.9
, Issue.5
, pp. 1470-1480
-
-
Madan, J.1
Baruah, B.2
Nagaraju, M.3
Abdalla, M.O.4
Yates, C.5
Turner, T.6
Rangari, V.7
Hamelberg, D.8
Aneja, R.9
-
85
-
-
84921515442
-
Inhalable nanostructured lipid particles of 9-bromo-noscapine, a tubulin-binding cytotoxic agent: Invitro and in vivo studies
-
Jyoti K, Kaur K, Pandey RS, Jain UK, Chandra R, Madan J. Inhalable nanostructured lipid particles of 9-bromo-noscapine, a tubulin-binding cytotoxic agent: Invitro and in vivo studies. J Colloid Interface Sci 2015;445C:219-230.
-
(2015)
J Colloid Interface Sci
, vol.445C
, pp. 219-230
-
-
Jyoti, K.1
Kaur, K.2
Pandey, R.S.3
Jain, U.K.4
Chandra, R.5
Madan, J.6
-
86
-
-
84904887791
-
Novel 9'-substituted-noscapines: Synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation
-
Porcu E, Sipos A, Basso G, Hamel E, Bai R, Stempfer V, Udvardy A, Benyei AC, Schmidhammer H, Antus S, Viola G. Novel 9'-substituted-noscapines: Synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation. Eur J Med Chem 2014;84:476-490.
-
(2014)
Eur J Med Chem
, vol.84
, pp. 476-490
-
-
Porcu, E.1
Sipos, A.2
Basso, G.3
Hamel, E.4
Bai, R.5
Stempfer, V.6
Udvardy, A.7
Benyei, A.C.8
Schmidhammer, H.9
Antus, S.10
Viola, G.11
-
87
-
-
33745168689
-
Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma
-
Aneja R, Vangapandu SN, Lopus M, Chandra R, Panda D, Joshi HC. Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma. Mol Pharmacol 2006;69(6):1801-1809.
-
(2006)
Mol Pharmacol
, vol.69
, Issue.6
, pp. 1801-1809
-
-
Aneja, R.1
Vangapandu, S.N.2
Lopus, M.3
Chandra, R.4
Panda, D.5
Joshi, H.C.6
-
88
-
-
0020082647
-
Continued expression of vinca alkaloid resistance by CCRF-CEM cells after treatment with tunicamycin or pronase
-
Beck WT, Cirtain MC. Continued expression of vinca alkaloid resistance by CCRF-CEM cells after treatment with tunicamycin or pronase. Cancer Res 1982;42(1):184-189.
-
(1982)
Cancer Res
, vol.42
, Issue.1
, pp. 184-189
-
-
Beck, W.T.1
Cirtain, M.C.2
-
89
-
-
0034641864
-
Differences in mutant p53 protein stability and functional activity in teniposide-sensitive and -resistant human leukemic CEM cells
-
Morgan SE, Kim R, Wang PC, Bhat UG, Kusumoto H, Lu T, Beck WT. Differences in mutant p53 protein stability and functional activity in teniposide-sensitive and -resistant human leukemic CEM cells. Oncogene 2000;19(43):5010-5019.
-
(2000)
Oncogene
, vol.19
, Issue.43
, pp. 5010-5019
-
-
Morgan, S.E.1
Kim, R.2
Wang, P.C.3
Bhat, U.G.4
Kusumoto, H.5
Lu, T.6
Beck, W.T.7
-
90
-
-
84904393934
-
Molecular insight of isotypes specific beta-tubulin interaction of tubulin heterodimer with noscapinoids
-
Santoshi S, Naik PK. Molecular insight of isotypes specific beta-tubulin interaction of tubulin heterodimer with noscapinoids. J Comput Aided Mol Des 2014;28(7):751-763.
-
(2014)
J Comput Aided Mol Des
, vol.28
, Issue.7
, pp. 751-763
-
-
Santoshi, S.1
Naik, P.K.2
-
91
-
-
84863266654
-
Tubulin binding, protein-bound conformation in solution, and antimitotic cellular profiling of noscapine and its derivatives
-
Bennani YL, Gu W, Canales A, Díaz FJ, Eustace BK, Hoover RR, Jiménez-Barbero J, Nezami A, Wang T. Tubulin binding, protein-bound conformation in solution, and antimitotic cellular profiling of noscapine and its derivatives. J Med Chem 2012;55(5):1920-1925.
-
(2012)
J Med Chem
, vol.55
, Issue.5
, pp. 1920-1925
-
-
Bennani, Y.L.1
Gu, W.2
Canales, A.3
Díaz, F.J.4
Eustace, B.K.5
Hoover, R.R.6
Jiménez-Barbero, J.7
Nezami, A.8
Wang, T.9
-
92
-
-
80051703052
-
Rational design, synthesis and biological evaluations of amino-noscapine: A high affinity tubulin-binding noscapinoid
-
Naik PK, Chatterji BP, Vangapandu SN, Aneja R, Chandra R, Kanteveri S, Joshi HC. Rational design, synthesis and biological evaluations of amino-noscapine: A high affinity tubulin-binding noscapinoid. J Comput Aided Mol Des 2011;25(5):443-454.
-
(2011)
J Comput Aided Mol Des
, vol.25
, Issue.5
, pp. 443-454
-
-
Naik, P.K.1
Chatterji, B.P.2
Vangapandu, S.N.3
Aneja, R.4
Chandra, R.5
Kanteveri, S.6
Joshi, H.C.7
-
93
-
-
84870285061
-
Synthesis and biological evaluation of N-substituted noscapine analogues
-
DeBono AJ, Xie JH, Ventura S, Pouton CW, Capuano B, Scammells PJ. Synthesis and biological evaluation of N-substituted noscapine analogues. ChemMedChem 2012;7(12):2122-2133.
-
(2012)
ChemMedChem
, vol.7
, Issue.12
, pp. 2122-2133
-
-
DeBono, A.J.1
Xie, J.H.2
Ventura, S.3
Pouton, C.W.4
Capuano, B.5
Scammells, P.J.6
-
94
-
-
79958092061
-
Second generation benzofuranone ring substituted noscapine analogs: Synthesis and biological evaluation
-
Mishra RC, Karna P, Gundala SR, Pannu V, Stanton RA, Gupta KK, Robinson MH, Lopus M, Wilson L, Henary M, Aneja R. Second generation benzofuranone ring substituted noscapine analogs: Synthesis and biological evaluation. Biochem Pharmacol 2011;82(2):110-121.
-
(2011)
Biochem Pharmacol
, vol.82
, Issue.2
, pp. 110-121
-
-
Mishra, R.C.1
Karna, P.2
Gundala, S.R.3
Pannu, V.4
Stanton, R.A.5
Gupta, K.K.6
Robinson, M.H.7
Lopus, M.8
Wilson, L.9
Henary, M.10
Aneja, R.11
-
95
-
-
84911935260
-
Synthesis and biological evaluation of novel biaryl type alpha-noscapine congeners
-
Manchukonda NK, Naik PK, Sridhar B, Kantevari S. Synthesis and biological evaluation of novel biaryl type alpha-noscapine congeners. Bioorg Med Chem Lett 2014;24(24):5752-5757.
-
(2014)
Bioorg Med Chem Lett
, vol.24
, Issue.24
, pp. 5752-5757
-
-
Manchukonda, N.K.1
Naik, P.K.2
Sridhar, B.3
Kantevari, S.4
-
96
-
-
84893568990
-
Rational design, synthesis, and biological evaluation of third generation alpha-noscapine analogues as potent tubulin binding anti-cancer agents
-
Manchukonda NK, Naik PK, Santoshi S, Lopus M, Joseph S, Sridhar B, Kantevari S. Rational design, synthesis, and biological evaluation of third generation alpha-noscapine analogues as potent tubulin binding anti-cancer agents. PLoS One 2013;8(10):e77970.
-
(2013)
PLoS One
, vol.8
, Issue.10
, pp. e77970
-
-
Manchukonda, N.K.1
Naik, P.K.2
Santoshi, S.3
Lopus, M.4
Joseph, S.5
Sridhar, B.6
Kantevari, S.7
-
97
-
-
84977771296
-
Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents
-
Santoshi S, Manchukonda NK, Suri C, Sharma M, Sridhar B, Joseph S, Lopus M, Kantevari S, Baitharu I, Naik PK. Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents. J Comput Aided Mol Des 2014.
-
(2014)
J Comput Aided Mol Des
-
-
Santoshi, S.1
Manchukonda, N.K.2
Suri, C.3
Sharma, M.4
Sridhar, B.5
Joseph, S.6
Lopus, M.7
Kantevari, S.8
Baitharu, I.9
Naik, P.K.10
-
99
-
-
0026001010
-
Papaveretum in women of childbearing potential
-
Sneyd JR. Papaveretum in women of childbearing potential. Brit Med J 1991;303(6806):852-852.
-
(1991)
Brit Med J
, vol.303
, Issue.6806
, pp. 852-852
-
-
Sneyd, J.R.1
-
100
-
-
70449216469
-
Noscapine
-
Noscapine. J Am Med Assoc 1958;167(8):993-994.
-
(1958)
J Am Med Assoc
, vol.167
, Issue.8
, pp. 993-994
-
-
-
101
-
-
0025992067
-
Noscapine-induced polyploidy in vitro
-
Mitchell ID, Carlton JB, Chan MY, Robinson A, Sunderland J. Noscapine-induced polyploidy in vitro. Mutagenesis 1991;6(6):479-486.
-
(1991)
Mutagenesis
, vol.6
, Issue.6
, pp. 479-486
-
-
Mitchell, I.D.1
Carlton, J.B.2
Chan, M.Y.3
Robinson, A.4
Sunderland, J.5
-
102
-
-
84877949750
-
A review on noscapine, and its impact on heme metabolism
-
Singh H, Singh P, Kumari K, Chandra A, Dass SK, Chandra R. A review on noscapine, and its impact on heme metabolism. Curr Drug Metab 2013;14(3):351-360.
-
(2013)
Curr Drug Metab
, vol.14
, Issue.3
, pp. 351-360
-
-
Singh, H.1
Singh, P.2
Kumari, K.3
Chandra, A.4
Dass, S.K.5
Chandra, R.6
-
103
-
-
84908335936
-
Novel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity
-
Henary M, Narayana L, Ahad S, Gundala SR, Mukkavilli R, Sharma V, Owens EA, Yadav Y, Nagaraju M, Hamelberg D, Tandon V, Panda D, Aneja R. Novel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity. Biochem Pharmacol 2014;92(2):192-205.
-
(2014)
Biochem Pharmacol
, vol.92
, Issue.2
, pp. 192-205
-
-
Henary, M.1
Narayana, L.2
Ahad, S.3
Gundala, S.R.4
Mukkavilli, R.5
Sharma, V.6
Owens, E.A.7
Yadav, Y.8
Nagaraju, M.9
Hamelberg, D.10
Tandon, V.11
Panda, D.12
Aneja, R.13
-
104
-
-
84870434926
-
Implications of nanoscale based drug delivery systems in delivery and targeting tubulin binding agent, noscapine in cancer cells
-
Chandra R, Madan J, Singh P, Chandra A, Kumar P, Tomar V, Dass SK. Implications of nanoscale based drug delivery systems in delivery and targeting tubulin binding agent, noscapine in cancer cells. Curr Drug Metab 2012;13(10):1476-1483.
-
(2012)
Curr Drug Metab
, vol.13
, Issue.10
, pp. 1476-1483
-
-
Chandra, R.1
Madan, J.2
Singh, P.3
Chandra, A.4
Kumar, P.5
Tomar, V.6
Dass, S.K.7
-
105
-
-
79958297166
-
Long-circulating poly(ethylene glycol)-grafted gelatin nanoparticles customized for intracellular delivery of noscapine: Preparation, in-vitro characterization, structure elucidation, pharmacokinetics, and cytotoxicity analyses
-
Madan J, Dhiman N, Sardana S, Aneja R, Chandra R, Katyal A. Long-circulating poly(ethylene glycol)-grafted gelatin nanoparticles customized for intracellular delivery of noscapine: Preparation, in-vitro characterization, structure elucidation, pharmacokinetics, and cytotoxicity analyses. Anticancer Drugs 2011;22(6):543-555.
-
(2011)
Anticancer Drugs
, vol.22
, Issue.6
, pp. 543-555
-
-
Madan, J.1
Dhiman, N.2
Sardana, S.3
Aneja, R.4
Chandra, R.5
Katyal, A.6
-
106
-
-
79952116455
-
Human serum albumin nanoparticles as an efficient noscapine drug delivery system for potential use in breast cancer: Preparation and in vitro analysis
-
Sebak S, Mirzaei M, Malhotra M, Kulamarva A, Prakash S. Human serum albumin nanoparticles as an efficient noscapine drug delivery system for potential use in breast cancer: Preparation and in vitro analysis. Int J Nanomed 2010;5:525-532.
-
(2010)
Int J Nanomed
, vol.5
, pp. 525-532
-
-
Sebak, S.1
Mirzaei, M.2
Malhotra, M.3
Kulamarva, A.4
Prakash, S.5
-
107
-
-
70350475941
-
Synthesis and characterization of noscapine loaded magnetic polymeric nanoparticles
-
Abdalla MO, Aneja R, Dean D, Rangari V, Russell A, Jaynes J, Yates C, Turner T. Synthesis and characterization of noscapine loaded magnetic polymeric nanoparticles. J Magn Magn Mater 2010;322(2):190-196.
-
(2010)
J Magn Magn Mater
, vol.322
, Issue.2
, pp. 190-196
-
-
Abdalla, M.O.1
Aneja, R.2
Dean, D.3
Rangari, V.4
Russell, A.5
Jaynes, J.6
Yates, C.7
Turner, T.8
|