Potent anti-inflammatory activity of novel microtubule-modulating brominated noscapine analogs

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Zughaier, Susu ^a   Karna, Prasanthi ^b   Stephens, David ^a   Aneja, Ritu ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; COLCHICINE; CYTOKINE; NOSCAPINE; TOLL LIKE RECEPTOR; ANTIINFLAMMATORY AGENT; ANTITUSSIVE AGENT; DRUG DERIVATIVE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; TUBULIN MODULATOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOPHAGY; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; SEPSIS; ANIMAL; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; HALOGENATION; METABOLISM; ULTRASTRUCTURE; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTITUSSIVE AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE; CHEMOKINE CXCL10; DOSE-RESPONSE RELATIONSHIP, DRUG; HALOGENATION; HUMANS; INTERLEUKIN-8; MACROPHAGES; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; NITRIC OXIDE; NOSCAPINE; REACTIVE OXYGEN SPECIES; TOLL-LIKE RECEPTOR 4; TUBULIN MODULATORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77949433802     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009165     Document Type: Article

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