-
1
-
-
0032539565
-
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells
-
Ye K, Ke Y, Keshava N, Shanks J, Kapp JA, Tekmal RR, et al. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells. Proc Natl Acad Sci U S A 1998; 95: 1601-6.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1601-1606
-
-
Ye, K.1
Ke, Y.2
Keshava, N.3
Shanks, J.4
Kapp, J.P.5
Tekmal, R.R.6
-
2
-
-
0037099621
-
Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma
-
Landen JW, Lang R, McMahon SJ, Rusan NM, Yvon AM, Adams AW, et al. Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma. Cancer Res 2002; 62: 4109-14.
-
(2002)
Cancer Res
, vol.62
, pp. 4109-4114
-
-
Landen, J.W.1
Lang, R.2
McMahon, S.J.3
Rusan, N.M.4
Yvon, A.M.5
Adams, A.W.6
-
3
-
-
0037053409
-
Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint
-
Zhou J, Panda D, Landen JW, Wilson L, Joshi HC. Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint. J Biol Chem 2002; 277: 17200-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 17200-17208
-
-
Zhou, J.1
Panda, D.2
Landen, J.W.3
Wilson, L.4
Joshi, H.C.5
-
4
-
-
0037131307
-
Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine
-
Zhou J, Gupta K, Yao J, Ye K, Panda D, Giannakakou P, et al. Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. J Biol Chem 2002; 277: 39777-85.
-
(2002)
J Biol Chem
, vol.277
, pp. 39777-39785
-
-
Zhou, J.1
Gupta, K.2
Yao, J.3
Ye, K.4
Panda, D.5
Giannakakou, P.6
-
5
-
-
0037106616
-
Attachment and tension in the spindle assembly checkpoint
-
Zhou J, Yao J, Joshi HC. Attachment and tension in the spindle assembly checkpoint. J Cell Sci 2002; 115: 3547-55.
-
(2002)
J Cell Sci
, vol.115
, pp. 3547-3555
-
-
Zhou, J.1
Yao, J.2
Joshi, H.C.3
-
6
-
-
4143090412
-
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth
-
Landen JW, Hau V, Wang M, Davis T, Ciliax B, Wainer BH, et al. Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth. Clin Cancer Res 2004; 10: 5187-201.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5187-5201
-
-
Landen, J.W.1
Hau, V.2
Wang, M.3
Davis, T.4
Ciliax, B.5
Wainer, B.H.6
-
7
-
-
0033928547
-
Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses
-
Ke Y, Ye K, Grossniklaus HE, Archer DR, Joshi HC, Kapp JA. Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses. Cancer Immunol Immunother 2000; 49: 217-25.
-
(2000)
Cancer Immunol Immunother
, vol.49
, pp. 217-225
-
-
Ke, Y.1
Ye, K.2
Grossniklaus, H.E.3
Archer, D.R.4
Joshi, H.C.5
Kapp, J.A.6
-
8
-
-
0018574846
-
Comparison of the antitussive effects of codeine phosphate 20 mg, dextromethorphan 30 mg and noscapine 30 mg using citric acid-induced cough in normal subjects
-
Empey DW, Laitinen LA, Young GA, Bye CE, Hughes DT. Comparison of the antitussive effects of codeine phosphate 20 mg, dextromethorphan 30 mg and noscapine 30 mg using citric acid-induced cough in normal subjects. Eur J Clin Pharmacol 1979; 16: 393-7.
-
(1979)
Eur J Clin Pharmacol
, vol.16
, pp. 393-397
-
-
Empey, D.W.1
Laitinen, L.A.2
Young, G.A.3
Bye, C.E.4
Hughes, D.T.5
-
9
-
-
0025010475
-
Pharmacokinetics of oral noscapine
-
Karlsson MO, Dahlstrom B, Eckernas SA, Johansson M, Alm AT. Pharmacokinetics of oral noscapine. Eur J Clin Pharmacol 1990; 39: 275-9.
-
(1990)
Eur J Clin Pharmacol
, vol.39
, pp. 275-279
-
-
Karlsson, M.O.1
Dahlstrom, B.2
Eckernas, S.A.3
Johansson, M.4
Alm, A.T.5
-
10
-
-
0023131037
-
Microtubule dynamics in vivo: A test of mechanisms of turnover
-
Sammak PJ, Gorbsky GJ, Borisy GG. Microtubule dynamics in vivo: a test of mechanisms of turnover. J Cell Biol 1987; 104: 395-405.
-
(1987)
J Cell Biol
, vol.104
, pp. 395-405
-
-
Sammak, P.J.1
Gorbsky, G.J.2
Borisy, G.G.3
-
12
-
-
68849087436
-
Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance
-
Perez EA. Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance. Mol Cancer Ther 2009; 8: 2086-95.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2086-2095
-
-
Perez, E.A.1
-
13
-
-
0029973041
-
Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance
-
Ranganathan S, Dexter DW, Benetatos CA, Chapman AE, Tew KD, Hudes GR. Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance. Cancer Res 1996; 56: 2584-9.
-
(1996)
Cancer Res
, vol.56
, pp. 2584-2589
-
-
Ranganathan, S.1
Dexter, D.W.2
Benetatos, C.A.3
Chapman, A.E.4
Tew, K.D.5
Hudes, G.R.6
-
14
-
-
0030758777
-
Paclitaxel-resistant human ovarian cancer cells have mutant betatubulins that exhibit impaired paclitaxel-driven polymerization
-
Giannakakou P, Sackett DL, Kang YK, Zhan Z, Buters JT, Fojo T, et al. Paclitaxel-resistant human ovarian cancer cells have mutant betatubulins that exhibit impaired paclitaxel-driven polymerization. J Biol Chem 1997; 272: 17118-25.
-
(1997)
J Biol Chem
, vol.272
, pp. 17118-17125
-
-
Giannakakou, P.1
Sackett, D.L.2
Kang, Y.K.3
Zhan, Z.4
Buters, J.T.5
Fojo, T.6
-
15
-
-
0033063875
-
Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations
-
Monzo M, Rosell R, Sanchez JJ, Lee JS, O'Brate A, Gonzalez-Larriba JL, et al. Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations. J Clin Oncol 1999; 17: 1786-93.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1786-1793
-
-
Monzo, M.1
Rosell, R.2
Sanchez, J.J.3
Lee, J.S.4
O'Brate, A.5
Gonzalez-Larriba, J.L.6
-
16
-
-
33745168689
-
Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma
-
Aneja R, Vangapandu SN, Lopus M, Chandra R, Panda D, Joshi HC. Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma. Mol Pharmacol 2006; 69: 1801-9.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 1801-1809
-
-
Aneja, R.1
Vangapandu, S.N.2
Lopus, M.3
Chandra, R.4
Panda, D.5
Joshi, H.C.6
-
17
-
-
0036795448
-
Local chemotherapy with cisplatin-depot for glioblastoma multiforme
-
Sheleg SV, Korotkevich EA, Zhavrid EA, Muravskaya GV, Smeyanovich AF, Shanko YG, et al. Local chemotherapy with cisplatin-depot for glioblastoma multiforme. J Neurooncol 2002; 60: 53-9.
-
(2002)
J Neurooncol
, vol.60
, pp. 53-59
-
-
Sheleg, S.V.1
Korotkevich, E.A.2
Zhavrid, E.A.3
Muravskaya, G.V.4
Smeyanovich, A.F.5
Shanko, Y.G.6
-
18
-
-
0036152786
-
P53 dependent apoptosis in glioma cell lines in response to hydrogen peroxide induced oxidative stress
-
Datta K, Babbar P, Srivastava T, Sinha S, Chattopadhyay P. p53 dependent apoptosis in glioma cell lines in response to hydrogen peroxide induced oxidative stress. Int J Biochem Cell Biol 2002; 34: 148-57.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 148-157
-
-
Datta, K.1
Babbar, P.2
Srivastava, T.3
Sinha, S.4
Chattopadhyay, P.5
-
19
-
-
0028153260
-
Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: A rational approach to clinical protocol design
-
Chou TC, Motzer RJ, Tong Y, Bosl GJ. Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J Natl Cancer Inst 1994; 86: 1517-24.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1517-1524
-
-
Chou, T.C.1
Motzer, R.J.2
Tong, Y.3
Bosl, G.J.4
-
20
-
-
33646829811
-
Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: A novel function for an old drug
-
Newcomb EW, Lukyanov Y, Schnee T, Ali MA, Lan L, Zagzag D. Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: a novel function for an old drug. Int J Oncol 2006; 28: 1121-30.
-
(2006)
Int J Oncol
, vol.28
, pp. 1121-1130
-
-
Newcomb, E.W.1
Lukyanov, Y.2
Schnee, T.3
Ali, M.A.4
Lan, L.5
Zagzag, D.6
-
22
-
-
33748794547
-
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
-
Chou TC. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 2006; 58: 621-81.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 621-681
-
-
Chou, T.C.1
-
23
-
-
53749106421
-
Noscapine induces apoptosis in human glioma cells by an apoptosisinducing factor-dependent pathway
-
Newcomb EW, Lukyanov Y, Smirnova I, Schnee T, Zagzag D. Noscapine induces apoptosis in human glioma cells by an apoptosisinducing factor-dependent pathway. Anticancer Drugs 2008; 19: 553-63.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 553-563
-
-
Newcomb, E.W.1
Lukyanov, Y.2
Smirnova, I.3
Schnee, T.4
Zagzag, D.5
-
24
-
-
18544372157
-
Elevated JNK activation contributes to the pathogenesis of human brain tumors
-
Antonyak MA, Kenyon LC, Godwin AK, James DC, Emlet DR, Okamoto I, et al. Elevated JNK activation contributes to the pathogenesis of human brain tumors. Oncogene 2002; 21: 5038-46.
-
(2002)
Oncogene
, vol.21
, pp. 5038-5046
-
-
Antonyak, M.A.1
Kenyon, L.C.2
Godwin, A.K.3
James, D.C.4
Emlet, D.R.5
Okamoto, I.6
-
25
-
-
84887212386
-
Possible novel therapy for malignant gliomas with secretable trimeric TRAIL
-
Jeong M, Kwon YS, Park SH, Kim CY, Jeun SS, Song KW, et al. Possible novel therapy for malignant gliomas with secretable trimeric TRAIL. PloS One 2009; 4: e4545.
-
(2009)
PloS One
, vol.4
-
-
Jeong, M.1
Kwon, Y.S.2
Park, S.H.3
Kim, C.Y.4
Jeun, S.S.5
Song, K.W.6
-
26
-
-
0141730399
-
Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide
-
Kanzawa T, Germano IM, Kondo Y, Ito H, Kyo S, Kondo S. Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide. Br J Cancer 2003; 89: 922-9.
-
(2003)
Br J Cancer
, vol.89
, pp. 922-929
-
-
Kanzawa, T.1
Germano, I.M.2
Kondo, Y.3
Ito, H.4
Kyo, S.5
Kondo, S.6
-
27
-
-
0032728210
-
Phase i dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies
-
Brada M, Judson I, Beale P, Moore S, Reidenberg P, Statkevich P, et al. Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies. Br J Cancer 1999; 81: 1022-30.
-
(1999)
Br J Cancer
, vol.81
, pp. 1022-1030
-
-
Brada, M.1
Judson, I.2
Beale, P.3
Moore, S.4
Reidenberg, P.5
Statkevich, P.6
-
28
-
-
0023793075
-
Potentiation of the antitumor activity of cisplatin in mice by 3-Aminobenzamide and nicotinamide
-
Chen G, Pan QC. Potentiation of the antitumor activity of cisplatin in mice by 3-Aminobenzamide and nicotinamide. Cancer Chemother Pharmacol 1988; 22: 303-7.
-
(1988)
Cancer Chemother Pharmacol
, vol.22
, pp. 303-307
-
-
Chen, G.1
Pan, Q.C.2
-
29
-
-
33645120003
-
New treatments for malignant gliomas: Careful evaluation and cautious optimism required
-
Gilbert MR. New treatments for malignant gliomas: careful evaluation and cautious optimism required. Ann Intern Med 2006; 144: 371-3.
-
(2006)
Ann Intern Med
, vol.144
, pp. 371-373
-
-
Gilbert, M.R.1
-
30
-
-
35448967382
-
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
-
Pyrko P, Schonthal AH, Hofman FM, Chen TC, Lee AS. The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res 2007; 67: 9809-16.
-
(2007)
Cancer Res
, vol.67
, pp. 9809-9816
-
-
Pyrko, P.1
Schonthal, A.H.2
Hofman, F.M.3
Chen, T.C.4
Lee, A.S.5
-
31
-
-
25444516747
-
Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme
-
Barrie M, Couprie C, Dufour H, Figarella-Branger D, Muracciole X, Hoang-Xuan K, et al. Temozolomide in combination with BCNU before and after radiotherapy in patients with inoperable newly diagnosed glioblastoma multiforme. Ann Oncol 2005; 16: 1177-84.
-
(2005)
Ann Oncol
, vol.16
, pp. 1177-1184
-
-
Barrie, M.1
Couprie, C.2
Dufour, H.3
Figarella-Branger, D.4
Muracciole, X.5
Hoang-Xuan, K.6
-
32
-
-
33646039750
-
Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro
-
Altinoz MA, Bilir A, Del Maestro RF, Tuna S, Ozcan E, Gedikoglu G. Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro. Surg Neurol 2006; 65: 478-84.
-
(2006)
Surg Neurol
, vol.65
, pp. 478-484
-
-
Altinoz, M.A.1
Bilir, A.2
Del Maestro, R.F.3
Tuna, S.4
Ozcan, E.5
Gedikoglu, G.6
-
33
-
-
80054006821
-
Noscapine inhibits tumor growth in TMZ-resistant gliomas
-
Jhaveri N, Cho H, Torres S, Wang W, Schonthal AH, Petasis NA, et al. Noscapine inhibits tumor growth in TMZ-resistant gliomas. Cancer Lett 2011; 312: 245-52.
-
(2011)
Cancer Lett
, vol.312
, pp. 245-252
-
-
Jhaveri, N.1
Cho, H.2
Torres, S.3
Wang, W.4
Schonthal, A.H.5
Petasis, N.A.6
-
34
-
-
77952564020
-
A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells
-
Aneja R, Miyagi T, Karna P, Ezell T, Shukla D, Vij Gupta M, et al. A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells. Eur J Cancer 2010; 46: 1668-78.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1668-1678
-
-
Aneja, R.1
Miyagi, T.2
Karna, P.3
Ezell, T.4
Shukla, D.5
Vij Gupta, M.6
|