Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5

Biochemistry

Volumn 54, Issue 30, 2015, Pages 4672-4682

  Chandrashekaran, Indu R ^a   Mohanty, Biswaranjan ^a   Linossi, Edmond M ^b,c   Dagley, Laura F ^b,c   Leung, Eleanor W W ^a   Murphy, James M ^b,c   Babon, Jeffrey J ^b,c   Nicholson, Sandra E ^b,c   Norton, Raymond S ^a  

^a MONASH UNIVERSITY   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ANALYSIS; CHEMICAL SHIFT; DNA SEQUENCES; ENZYME ACTIVITY; PHOSPHORYLATION;

EXTENDED STRUCTURES; FUNCTIONAL CHARACTERIZATION; NUCLEAR MAGNETIC RESONANCE CHEMICAL SHIFTS; PHOSPHORYLATION SITES; PROTEIN INTERACTION; RELAXATION MEASUREMENTS; SITE DIRECTED MUTAGENESIS; SOLUTION CONFORMATIONS;

NUCLEAR MAGNETIC RESONANCE;

INTRINSICALLY DISORDERED PROTEIN; JANUS KINASE; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 5; UNCLASSIFIED DRUG; SOCS5 PROTEIN, MOUSE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; DISSOCIATION CONSTANT; HUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; SURFACE PLASMON RESONANCE; AMINO ACID SUBSTITUTION; ANIMAL; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; MOUSE; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SUBSTITUTION; ANIMALS; MICE; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PHOSPHORYLATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84938578538     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00619     Document Type: Article

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