Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

Nature

Volumn 519, Issue 7541, 2015, Pages 106-109

  Bah, Alaji ^a,b   Vernon, Robert M ^a,b   Siddiqui, Zeba ^a   Krzeminski, Mickaël ^a,b   Muhandiram, Ranjith ^b   Zhao, Charlie ^a   Sonenberg, Nahum ^c   Kay, Lewis E ^a,b,d   Forman Kay, Julie D ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4B; INITIATION FACTOR 4E; INTRINSICALLY DISORDERED PROTEIN; EIF4EBP2 PROTEIN, HUMAN; INITIATION FACTOR; PROTEIN BINDING;

ARTICLE; BETA SHEET; BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TRANSLATION INITIATION; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; SIGNAL TRANSDUCTION;

BINDING SITES; EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTORS; HUMANS; INTRINSICALLY DISORDERED PROTEINS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SIGNAL TRANSDUCTION;

EID: 84925538272     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13999     Document Type: Article

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