Protective efficacy of carnosic acid against hydrogen peroxide induced oxidative injury in HepG2 cells through the SIRT1 pathway

Canadian Journal of Physiology and Pharmacology

Volumn 93, Issue 8, 2015, Pages 625-631

  Hu, Yan ^a   Zhang, Ning ^a   Fan, Qing ^a   Lin, Musen ^a   Zhang, Ce ^a   Fan, Guangjun ^a   Zhai, Xiaohan ^a   Zhang, Feng ^a   Chen, Zhao ^a   Yao, Jihong ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Carnosic acid; HepG2 cells; Hydrogen peroxide; Reactive oxygen species; SIRT1

Indexed keywords

CARNOSIC ACID; CASPASE 3; GLUTATHIONE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; SELISISTAT; SIRTUIN 1; SMALL INTERFERING RNA; ABIETANE DERIVATIVE; ANTIOXIDANT; OXIDIZING AGENT; SIRT1 PROTEIN, HUMAN;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL; LIVER INJURY; LIVER PROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION; CELL PROTECTION; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; RNA INTERFERENCE;

ANTIOXIDANTS; APOPTOSIS; CYTOPROTECTION; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; OXIDATIVE STRESS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SIRTUIN 1; TRANSFECTION;

EID: 84938560810     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2014-0513     Document Type: Article

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