Mass spectrometry-based metabolite profiling in the mouse liver following exposure to ultraviolet B radiation

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Park, Hye Min ^a   Shon, Jong Cheol ^b   Lee, Mee Youn ^a   Liu, Kwang Hyeon ^b   Kim, Jeong Kee ^c   Lee, Sang Jun ^c   Lee, Choong Hwan ^a  

^a Konkuk University   (South Korea)

^b Kyungpook National University   (South Korea)

^c AmorePacific Corporation   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CARBOHYDRATE; CHOLESTEROL; CHOLIC ACID; FATTY ACID; GLUTAMINE; LYSOPHOSPHOLIPID; NUCLEOSIDE; PHOSPHOLIPID; TAURINE CONJUGATED CHOLIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GAS CHROMATOGRAPHY; HAIRLESS MOUSE; LIVER; LIVER METABOLISM; LONG TERM EXPOSURE; MASS SPECTROMETRY; METABOLITE; METABOLOMICS; MOUSE; NONHUMAN; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET B RADIATION; ANIMAL; METABOLISM; METABOLOME; PROCEDURES; RADIATION RESPONSE; SKIN; ULTRAVIOLET RADIATION;

ANIMALS; FEMALE; LIVER; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; MICE, HAIRLESS; SKIN; ULTRAVIOLET RAYS;

EID: 84907501719     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109479     Document Type: Article

References (48)

1. Piltingsrud HV, Odland LT, Fong C.W. (1976) An evaluation of fluorescent light sources for use in phototherapy of neonatal jaundice. Am Ind Hyg Assoc J 37: 437-444.
2. Bishop SC (1979) DNA repair synthesis in human skin exposed to ultraviolet radiation used in PUVA (psoralen and UV-A) therapy for psoriasis. Br J Dermatol 101: 399-405.
3. Midelfart K, Stenvold SE, Volden G. (1985) Combined UVB and UVA phototherapy of atopic eczema. Dermatologica 171: 95-98.
4. El-Zawahry B.M., Bassiouny DA, Sobhi R.M., Abdel-Aziz E, Zaki NS, et al (2012) A comparative study on efficacy of UVA1 vs. narrow-band UVB phototherapy in the treatment of vitiligo. Photodermatol Photoimmunol Photomed 28: 84-90.
5. Ravanat JL, Douki T, Cadet J. (2001) Direct and indirect effects of UV radiation on DNA and its components. J Photochem Photobiol B 63: 88-102.
6. Trautinger F (2001) Mechanisms of photodamage of the skin and its functional consequences for skin ageing. Clin Exp Dermatol 26: 573-577.
7. Svobodova A, Walterova D, Vostalova J. (2006) Ultraviolet light induced alteration to the skin. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 150: 25-38.
8. Verschooten L, Claerhout S, Van Laethem A, Agostinis P, Garmyn M. (2006) New strategies of photopro tection. Photochem Photobiol 82: 1016-1023.
9. Park HM, Shin JH, Kim J.K., Lee SJ, Hwang GS, et al. (2013) MS-based metabolite profiling reveals time-dependent skin biomarkers in UVB-irradiated mice. Metabolomics. In press Doi: 10.1007/s11306-013-0594-x.
10. Svobodová AR, Galandáková A, Sianská J, Doležal D, Ulrichová J, et al. (2011) Acute exposure to solar simulated ultraviolet radiation affects oxidative stress-related biomarkers in skin, liver and blood of hairless mice. Biol Pharm Bull 34: 471-479.
11. Vinayavekhin N, Homan EA, Saghatelian A. (2010) Exploring disease through metabolomics. ACS Chem Biol 5: 91-103.
12. (1)H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue. Magn Reson Med 45: 781-790.
13. Kim HJ, Kim JH, Noh S, Hur H.J., Sung MJ, et al. (2011) Metabolomic analysis of livers and serum from high-fat diet induced obese mice. J Proteome Res 10: 722-731.
14. Kim J, Choi JN, Choi J.H., Cha YS, Muthaiya MJ, et al. (2013) Effect of fermented soybean product (Cheonggukjang) intake on metabolic parameters in mice fed a high-fat diet. Mol Nutr Food Res 57: 1886-1891.
15. Masson P, Alves AC, Ebbels T.M., Nicholson JK, Want E.J. (2010) Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS. Anal Chem 82: 7779-7786.
16. Kind T, Liu KH, Lee do Y, DeFelice B, Meissen J.K., et al. (2013) LipidBlast in silico tandem mass spectrometry database for lipid identification. Nat Methods 10: 755-758.
17. Brosnan ME, Brosnan J.T. (2007) The Textbook of Hepatology: From Basic Science to Clinical Practice, 3rd Edition. Wiley-Blackwell, UK. 142-149.
18. Watford M (2000) Glutamine and glutamate metabolism across the liver sinusoid. J Nutr 130: 983S-987S.
19. Yang D, Brunengraber H. (2000) Glutamate, a window on liver intermediary metabolism. J Nutr 130: 991S-994S.
20. Newsholme P, Procopio J, Lima M.M., Pithon-Curi TC, Curi R. (2003) Glutamine and glutamate-their central role in cell metabolism and function. Cell Biochem Funct 21: 1-9.
21. Brosnan ME, Brosnan J.T. (2009) Hepatic glutamate metabolism: a tale of 2 hepatocytes. Am J Clin Nutr 90: 857S-861S.
22. Watford M, Chellaraj V, Ismat A., Brown P, Raman P. (2002) Hepatic glutamine metabolism. Nutrition 18: 301-303.
23. Shambaugh GE 3rd (1977) Urea biosynthesis I. The urea cycle and relationships to the citric acid cycle. Am J Clin Nutr 30: 2083-2087.
24. Sherwin RS (1980) Role of the liver in glucose homeostasis. Diabetes Care 3: 261-265.
25. Postic C, Dentin R, Girard J. (2004) Role of the liver in the control of carbohydrate and lipid homeostasis. Diabetes Metab 30: 398-408.
26. Nguyen P, Leray V, Diez M., Serisier S, Le Bloc'h J, et al. (2008) Liver lipid metabolism. J Anim Physiol Anim Nutr (Berl) 92: 272-283.
27. Bechmann LP, Hannivoort RA, Gerken G, Hotamisligil G.S., Trauner M., et al. (2012) The interaction of hepatic lipid and glucose metabolism in liver diseases. J Hepatol 56: 952-964.
28. Bradbury MW (2006) Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis. Am J Physiol Gastrointest Liver Physiol 290: G194-198.
29. Calder PC (2006) n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr 83: 1505S-1519S.
30. Calder PC (2009) Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale. Biochimie 91: 791-795.
31. Chavez-Tapia N.C., Rosso N, Tiribelli C. (2012) Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease. BMC Gastroenterol 12: 20.
32. Leamy AK, Egnatchik RA, Young J.D. (2013) Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease. Prog Lipid Res 52: 165-174.
33. Li Z, Agellon LB, Allen T.M., Umeda M., Jewell L, et al. (2006) The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metab 3: 321-331.
34. Perrin-Cocon L., Agaugué S, Coutant F, Saint-Mézard P, Guironnet-Paquet A, et al. (2006) Lysophosphatidylcholine is a natural adjuvant that initiates cellular immune responses. Vaccine 24: 1254-1263.
35. Olofsson KE, Andersson L, Nilsson J., Björkbacka H (2008) Nanomolar concentrations of lysophosphatidylcholine recruit monocytes and induce pro-inflammatory cytokine production in macrophages. Biochem Biophys Res Commun 370: 348-352.
36. Hung ND, Sok DE, Kim M.R. (2012) Prevention of 1-palmitoyl lysophospha-tidylcholine-induced inflammation by polyunsaturated acyl lysophosphatidyl-choline. Inflamm Res 61: 473-483.
37. Le TT, Ziemba A, Urasaki Y., Hayes E, Brotman S, et al (2013) Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation. J Lipid Res 54: 1044-1057.
38. Haskó G, Kuhel DG, Németh ZH, Mabley JG, Stachlewitz RF, et al. (2000) Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock. J Immunol 164: 1013-1019.
39. Liaudet L, Mabley JG, Soriano F.G., Pacher P., Marton A, et al. (2001) Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture. Am J Respir Crit Care Med 164: 1213-1220.
40. Vessey DA (1978) The biochemical basis for the conjugation of bile acids with either glycine or taurine. Biochem J 174: 621-626.
41. Häussinger D (2004) Neural control of hepatic osmolytes and parenchymal cell hydration. Anat. Rec. A Discov. Mol Cell Evol Biol 280: 893-900.
42. Refik Mas M., Comert B, Oncu K., Vural SA, Akay C, et al. (2004) The effect of taurine treatment on oxidative stress in experimental liver fibrosis. Hepatol Res 28: 207-215.
43. Das J, Roy A, Sil P.C. (2012) Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review. Food Funct 3: 1251-1264.
44. Murphy GM, Signer E. (1974) Bile acid metabolism in infants and children. Gut 15: 151-163.
45. Hardison WG, Proffitt J.H. (1977) Influence of hepatic taurine concentration on bile acid conjugation with taurine. Am J Physiol 232: E75-79.
46. Hardison WG (1978) Hepatic taurine concentration and dietary taurine as regulators of bile acid conjugation with taurine. Gastroenterology 75: 71-75.
47. Hofmann AF (1999) The continuing importance of bile acids in liver and intestinal disease. Arch Intern Med 159: 2647-2658.
48. Staels B, Fonseca V.A. (2009) Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. Diabetes Care 32: S237-245.