메뉴 건너뛰기




Volumn 17, Issue 7, 2015, Pages 832-849

Mesenchymal stromal cells and rheumatic diseases: New tools from pathogenesis to regenerative therapies

Author keywords

Mesenchymal stromal cells; Pathogenesis; Regenerative therapy; Rheumatic disease

Indexed keywords

AGGRECANASE; CHONDROITIN SULFATE; CYCLOPHOSPHAMIDE; DEXAMETHASONE; GLUCOSAMINE; MATRIX METALLOPROTEINASE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEGA 3 FATTY ACID; PROSTAGLANDIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 84938072379     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2014.12.006     Document Type: Review
Times cited : (24)

References (148)
  • 1
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315-317.
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3    Slaper-Cortenbach, I.4    Marini, F.5    Krause, D.6
  • 2
    • 70349580508 scopus 로고    scopus 로고
    • Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases
    • Djouad F., BouffiC., Ghannam S., Noël D., Jorgensen C. Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat Rev Rheumatol 2009, 5:392-399.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 392-399
    • Djouad, F.1    Bouffi, C.2    Ghannam, S.3    Noël, D.4    Jorgensen, C.5
  • 4
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew A., Sturgeon C., Siatskas M., Ferrer K., McIntosh K., Patil S., et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002, 30:42-48.
    • (2002) Exp Hematol , vol.30 , pp. 42-48
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3    Ferrer, K.4    McIntosh, K.5    Patil, S.6
  • 5
    • 79955105244 scopus 로고    scopus 로고
    • Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases
    • Ben-Ami E., Berrih-Aknin S., Miller A. Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases. Autoimmun Rev 2011, 10:410-415.
    • (2011) Autoimmun Rev , vol.10 , pp. 410-415
    • Ben-Ami, E.1    Berrih-Aknin, S.2    Miller, A.3
  • 6
    • 84877806000 scopus 로고    scopus 로고
    • Stem cells in autoimmune diseases: Implications for pathogenesis and future trends in therapy
    • Cipriani P., Carubbi F., Liakouli V., Marrelli A., Perricone C., Perricone R., et al. Stem cells in autoimmune diseases: Implications for pathogenesis and future trends in therapy. Autoimmun Rev 2013, 12:709-716.
    • (2013) Autoimmun Rev , vol.12 , pp. 709-716
    • Cipriani, P.1    Carubbi, F.2    Liakouli, V.3    Marrelli, A.4    Perricone, C.5    Perricone, R.6
  • 7
    • 33847386693 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro
    • Bocelli-Tyndall C., Bracci L., Spagnoli G., Braccini A., Bouchenaki M., Ceredig R., et al. Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro. Rheumatology (Oxford) 2007, 46:403-408.
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 403-408
    • Bocelli-Tyndall, C.1    Bracci, L.2    Spagnoli, G.3    Braccini, A.4    Bouchenaki, M.5    Ceredig, R.6
  • 8
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M., Glennie S., Dyson J., Scott D., Laylor R., Simpson E., et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003, 101:3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6
  • 9
    • 67649889096 scopus 로고    scopus 로고
    • Heterogeneity of multipotent mesenchymal stromal cells: from stromal cells to stem cells and vice versa
    • Dominici M., Paolucci P., Conte P., Horwitz E.M. Heterogeneity of multipotent mesenchymal stromal cells: from stromal cells to stem cells and vice versa. Transplantation 2009, 87(9 Suppl):S36-42.
    • (2009) Transplantation , vol.87 , Issue.9 , pp. S36-S42
    • Dominici, M.1    Paolucci, P.2    Conte, P.3    Horwitz, E.M.4
  • 10
    • 33749646189 scopus 로고    scopus 로고
    • Adult stem cells in the treatment of autoimmune diseases
    • van Laar J.M., Tyndall A. Adult stem cells in the treatment of autoimmune diseases. Rheumatology (Oxford) 2006, 45:1187-1193.
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1187-1193
    • van Laar, J.M.1    Tyndall, A.2
  • 11
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M., Carlo-Stella C., Magni M., Milanesi M., Longoni P.D., Matteucci P., et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002, 99:3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6
  • 12
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • Zappia E., Casazza S., Pedemonte E., Benvenuto F., Bonanni I., Gerdoni E., et al. Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. Blood 2005, 106:1755-1761.
    • (2005) Blood , vol.106 , pp. 1755-1761
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3    Benvenuto, F.4    Bonanni, I.5    Gerdoni, E.6
  • 13
    • 70349881103 scopus 로고    scopus 로고
    • Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner
    • Rafei M., Campeau P.M., Aguilar-Mahecha A., Buchanan M., Williams P., Birman E., et al. Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner. J Immunol 2009, 182:5994-6002.
    • (2009) J Immunol , vol.182 , pp. 5994-6002
    • Rafei, M.1    Campeau, P.M.2    Aguilar-Mahecha, A.3    Buchanan, M.4    Williams, P.5    Birman, E.6
  • 14
    • 70350212973 scopus 로고    scopus 로고
    • Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitis
    • Constantin G., Marconi S., Rossi B., Angiari S., Calderan L., Anghileri E., et al. Adipose-derived mesenchymal stem cells ameliorate chronic experimental autoimmune encephalomyelitis. Stem Cells 2009, 27:2624-2635.
    • (2009) Stem Cells , vol.27 , pp. 2624-2635
    • Constantin, G.1    Marconi, S.2    Rossi, B.3    Angiari, S.4    Calderan, L.5    Anghileri, E.6
  • 17
    • 79960137010 scopus 로고    scopus 로고
    • Clinical comorbidities, treatment patterns, and direct medical costs of patients with osteoarthritis in usual care: a retrospective claims database analysis
    • Gore M., Tai K.S., Sadosky A., Leslie D., Stacey B.R. Clinical comorbidities, treatment patterns, and direct medical costs of patients with osteoarthritis in usual care: a retrospective claims database analysis. J Med Econ 2011, 14:497-507.
    • (2011) J Med Econ , vol.14 , pp. 497-507
    • Gore, M.1    Tai, K.S.2    Sadosky, A.3    Leslie, D.4    Stacey, B.R.5
  • 18
    • 19344376377 scopus 로고    scopus 로고
    • Assessing the burden of disease in the United States using disability-adjusted life years
    • McKenna M.T., Michaud C.M., Murray C.J., Marks J.S. Assessing the burden of disease in the United States using disability-adjusted life years. Am J Prev Med 2005, 28:415-423.
    • (2005) Am J Prev Med , vol.28 , pp. 415-423
    • McKenna, M.T.1    Michaud, C.M.2    Murray, C.J.3    Marks, J.S.4
  • 19
    • 84855993582 scopus 로고    scopus 로고
    • Biomechanical factors in osteoarthritis
    • Guilak F. Biomechanical factors in osteoarthritis. Best Pract Res Clin Rheumatol 2011, 25:815-823.
    • (2011) Best Pract Res Clin Rheumatol , vol.25 , pp. 815-823
    • Guilak, F.1
  • 20
    • 77950659332 scopus 로고    scopus 로고
    • Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis
    • Goldring M.B., Goldring S.R. Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis. Ann N Y Acad Sci 2010, 1192:230-237.
    • (2010) Ann N Y Acad Sci , vol.1192 , pp. 230-237
    • Goldring, M.B.1    Goldring, S.R.2
  • 21
    • 84893782280 scopus 로고    scopus 로고
    • Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis
    • Stone A.V., Loeser R.F., Vanderman K.S., Long D.L., Clark S.C., Ferguson C.M. Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis. Osteoarthritis Cartilage 2014, 22:264-274.
    • (2014) Osteoarthritis Cartilage , vol.22 , pp. 264-274
    • Stone, A.V.1    Loeser, R.F.2    Vanderman, K.S.3    Long, D.L.4    Clark, S.C.5    Ferguson, C.M.6
  • 23
    • 18244384041 scopus 로고    scopus 로고
    • Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis - results of a 1 year longitudinal arthroscopic study in 422 patients
    • Ayral X., Pickering E.H., Woodworth T.G., Mackillop N., Dougados M. Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis - results of a 1 year longitudinal arthroscopic study in 422 patients. Osteoarthritis Cartilage 2005, 13:361-367.
    • (2005) Osteoarthritis Cartilage , vol.13 , pp. 361-367
    • Ayral, X.1    Pickering, E.H.2    Woodworth, T.G.3    Mackillop, N.4    Dougados, M.5
  • 25
    • 84885319351 scopus 로고    scopus 로고
    • Mesenchymal stem cells in joint disease and repair
    • Barry F., Murphy M. Mesenchymal stem cells in joint disease and repair. Nat Rev Rheumatol 2013, 9:584-594.
    • (2013) Nat Rev Rheumatol , vol.9 , pp. 584-594
    • Barry, F.1    Murphy, M.2
  • 27
    • 0034881402 scopus 로고    scopus 로고
    • Multipotent mesenchymal stem cells from adult human synovial membrane
    • De Bari C., Dell'Accio F., Tylzanowski P., Luyten F.P. Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 2001, 44:1928-1942.
    • (2001) Arthritis Rheum , vol.44 , pp. 1928-1942
    • De Bari, C.1    Dell'Accio, F.2    Tylzanowski, P.3    Luyten, F.P.4
  • 28
    • 45349097371 scopus 로고    scopus 로고
    • Synovial fluid mesenchymal stem cells in health and early osteoarthritis: detection and functional evaluation at the single-cell level
    • Jones E.A., Crawford A., English A., Henshaw K., Mundy J., Corscadden D., et al. Synovial fluid mesenchymal stem cells in health and early osteoarthritis: detection and functional evaluation at the single-cell level. Arthritis Rheum 2008, 58:1731-1740.
    • (2008) Arthritis Rheum , vol.58 , pp. 1731-1740
    • Jones, E.A.1    Crawford, A.2    English, A.3    Henshaw, K.4    Mundy, J.5    Corscadden, D.6
  • 29
    • 84857624671 scopus 로고    scopus 로고
    • Fat pad-derived mesenchymal stem cells as a potential source for cell-based adipose tissue repair strategies
    • Khan W.S., Adesida A.B., Tew S.R., Longo U.G., Hardingham T.E. Fat pad-derived mesenchymal stem cells as a potential source for cell-based adipose tissue repair strategies. Cell Prolif 2012, 45:111-120.
    • (2012) Cell Prolif , vol.45 , pp. 111-120
    • Khan, W.S.1    Adesida, A.B.2    Tew, S.R.3    Longo, U.G.4    Hardingham, T.E.5
  • 31
    • 57949107562 scopus 로고    scopus 로고
    • Isolation and characterization of mesenchymal stromal cells from human anterior cruciate ligament
    • Huang T.F., Chen Y.T., Yang T.H., Chen L.L., Chiou S.H., Tsai T.H., et al. Isolation and characterization of mesenchymal stromal cells from human anterior cruciate ligament. Cytotherapy 2008, 10:806-814.
    • (2008) Cytotherapy , vol.10 , pp. 806-814
    • Huang, T.F.1    Chen, Y.T.2    Yang, T.H.3    Chen, L.L.4    Chiou, S.H.5    Tsai, T.H.6
  • 32
    • 63349099190 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles
    • Segawa Y., Muneta T., Makino H., Nimura A., Mochizuki T., Ju Y.J., et al. Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles. J Orthop Res 2009, 27:435-441.
    • (2009) J Orthop Res , vol.27 , pp. 435-441
    • Segawa, Y.1    Muneta, T.2    Makino, H.3    Nimura, A.4    Mochizuki, T.5    Ju, Y.J.6
  • 33
    • 0036125407 scopus 로고    scopus 로고
    • Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis
    • Murphy J.M., Dixon K., Beck S., Fabian D., Feldman A., Barry F. Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum 2002, 46:704-713.
    • (2002) Arthritis Rheum , vol.46 , pp. 704-713
    • Murphy, J.M.1    Dixon, K.2    Beck, S.3    Fabian, D.4    Feldman, A.5    Barry, F.6
  • 34
    • 36549054396 scopus 로고    scopus 로고
    • Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology
    • Scharstuhl A., Schewe B., Benz K., Gaissmaier C., Bühring H.J., Stoop R. Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology. Stem Cells 2007, 25:3244-3251.
    • (2007) Stem Cells , vol.25 , pp. 3244-3251
    • Scharstuhl, A.1    Schewe, B.2    Benz, K.3    Gaissmaier, C.4    Bühring, H.J.5    Stoop, R.6
  • 35
    • 33646365065 scopus 로고    scopus 로고
    • Chondrogenic differentiation of mesenchymal stem cells isolated from patients in late adulthood: the optimal conditions of growth factors
    • Im G.I., Jung N.H., Tae S.K. Chondrogenic differentiation of mesenchymal stem cells isolated from patients in late adulthood: the optimal conditions of growth factors. Tissue Eng 2006, 12:527-536.
    • (2006) Tissue Eng , vol.12 , pp. 527-536
    • Im, G.I.1    Jung, N.H.2    Tae, S.K.3
  • 36
    • 79959515249 scopus 로고    scopus 로고
    • Inhibition of cellular senescence by developmentally regulated FGF receptors in mesenchymal stem cells
    • Coutu D.L., François M., Galipeau J. Inhibition of cellular senescence by developmentally regulated FGF receptors in mesenchymal stem cells. Blood 2011, 117:6801-6812.
    • (2011) Blood , vol.117 , pp. 6801-6812
    • Coutu, D.L.1    François, M.2    Galipeau, J.3
  • 37
    • 0035154270 scopus 로고    scopus 로고
    • Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age
    • De Bari C., Dell'Accio F., Luyten F.P. Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age. Arthritis Rheum 2001, 44:85-95.
    • (2001) Arthritis Rheum , vol.44 , pp. 85-95
    • De Bari, C.1    Dell'Accio, F.2    Luyten, F.P.3
  • 38
    • 77954239605 scopus 로고    scopus 로고
    • Large-scale extraction and characterization of CD271+ multipotential stromal cells from trabecular bone in health and osteoarthritis: implications for bone regeneration strategies based on uncultured or minimally cultured multipotential stromal cells
    • Jones E., English A., Churchman S.M., Kouroupis D., Boxall S.A., Kinsey S., et al. Large-scale extraction and characterization of CD271+ multipotential stromal cells from trabecular bone in health and osteoarthritis: implications for bone regeneration strategies based on uncultured or minimally cultured multipotential stromal cells. Arthritis Rheum 2010, 62:1944-1954.
    • (2010) Arthritis Rheum , vol.62 , pp. 1944-1954
    • Jones, E.1    English, A.2    Churchman, S.M.3    Kouroupis, D.4    Boxall, S.A.5    Kinsey, S.6
  • 39
    • 33747097813 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells in adult human articular cartilage
    • Hiraoka K., Grogan S., Olee T., Lotz M. Mesenchymal progenitor cells in adult human articular cartilage. Biorheology 2006, 43:447-454.
    • (2006) Biorheology , vol.43 , pp. 447-454
    • Hiraoka, K.1    Grogan, S.2    Olee, T.3    Lotz, M.4
  • 40
    • 62949120743 scopus 로고    scopus 로고
    • Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis
    • Koelling S., Kruegel J., Irmer M., Path J.R., Sadowski B., Miro X., et al. Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis. Cell Stem Cell 2009, 4:324-335.
    • (2009) Cell Stem Cell , vol.4 , pp. 324-335
    • Koelling, S.1    Kruegel, J.2    Irmer, M.3    Path, J.R.4    Sadowski, B.5    Miro, X.6
  • 41
    • 15844384854 scopus 로고    scopus 로고
    • ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
    • Stanton H., Rogerson F.M., East C.J., Golub S.B., Lawlor K.E., Meeker C.T., et al. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature 2005, 434:648-652.
    • (2005) Nature , vol.434 , pp. 648-652
    • Stanton, H.1    Rogerson, F.M.2    East, C.J.3    Golub, S.B.4    Lawlor, K.E.5    Meeker, C.T.6
  • 42
    • 15844413814 scopus 로고    scopus 로고
    • Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
    • Glasson S.S., Askew R., Sheppard B., Carito B., Blanchet T., Ma H.L., et al. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005, 434:644-648.
    • (2005) Nature , vol.434 , pp. 644-648
    • Glasson, S.S.1    Askew, R.2    Sheppard, B.3    Carito, B.4    Blanchet, T.5    Ma, H.L.6
  • 43
    • 84857034827 scopus 로고    scopus 로고
    • Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5
    • Wang V.M., Bell R.M., Thakore R., Eyre D.R., Galante J.O., Li J., et al. Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5. J Orthop Res 2012, 30:620-626.
    • (2012) J Orthop Res , vol.30 , pp. 620-626
    • Wang, V.M.1    Bell, R.M.2    Thakore, R.3    Eyre, D.R.4    Galante, J.O.5    Li, J.6
  • 44
    • 79960390318 scopus 로고    scopus 로고
    • Adamts5 deletion blocks murine dermal repair through CD44-mediated aggrecan accumulation and modulation of transforming growth factor β1 (TGFβ1) signaling
    • Velasco J., Li J., DiPietro L., Stepp M.A., Sandy J.D., Plaas A. Adamts5 deletion blocks murine dermal repair through CD44-mediated aggrecan accumulation and modulation of transforming growth factor β1 (TGFβ1) signaling. J Biol Chem 2011, 286:26016-26027.
    • (2011) J Biol Chem , vol.286 , pp. 26016-26027
    • Velasco, J.1    Li, J.2    DiPietro, L.3    Stepp, M.A.4    Sandy, J.D.5    Plaas, A.6
  • 45
    • 33746886283 scopus 로고    scopus 로고
    • Animal models of osteoarthritis: lessons learned while seeking the "Holy Grail"
    • Ameye L.G., Young M.F. Animal models of osteoarthritis: lessons learned while seeking the "Holy Grail". Curr Opin Rheumatol 2006, 18:537-547.
    • (2006) Curr Opin Rheumatol , vol.18 , pp. 537-547
    • Ameye, L.G.1    Young, M.F.2
  • 46
    • 47149103922 scopus 로고    scopus 로고
    • Technology insight: adult mesenchymal stem cells for osteoarthritis therapy
    • Nöth U., Steinert A.F., Tuan R.S. Technology insight: adult mesenchymal stem cells for osteoarthritis therapy. Nat Clin Pract Rheumatol 2008, 4:371-380.
    • (2008) Nat Clin Pract Rheumatol , vol.4 , pp. 371-380
    • Nöth, U.1    Steinert, A.F.2    Tuan, R.S.3
  • 48
    • 84895171384 scopus 로고    scopus 로고
    • Therapeutic application of mesenchymal stem cells in bone and joint diseases
    • Liu Y., Wu J., Zhu Y., Han J. Therapeutic application of mesenchymal stem cells in bone and joint diseases. Clin Exp Med 2014, 14:13-24.
    • (2014) Clin Exp Med , vol.14 , pp. 13-24
    • Liu, Y.1    Wu, J.2    Zhu, Y.3    Han, J.4
  • 49
    • 77955565285 scopus 로고    scopus 로고
    • Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study
    • Lee C.H., Cook J.L., Mendelson A., Moioli E.K., Yao H., Mao J.J. Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet 2010, 376:440-448.
    • (2010) Lancet , vol.376 , pp. 440-448
    • Lee, C.H.1    Cook, J.L.2    Mendelson, A.3    Moioli, E.K.4    Yao, H.5    Mao, J.J.6
  • 51
    • 24144451066 scopus 로고    scopus 로고
    • Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis
    • Wang Y., Belflower R.M., Dong Y.F., Schwarz E.M., O'Keefe R.J., Drissi H. Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis. J Bone Miner Res 2005, 20:1624-1636.
    • (2005) J Bone Miner Res , vol.20 , pp. 1624-1636
    • Wang, Y.1    Belflower, R.M.2    Dong, Y.F.3    Schwarz, E.M.4    O'Keefe, R.J.5    Drissi, H.6
  • 52
    • 53249121835 scopus 로고    scopus 로고
    • Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival
    • Wotton S., Terry A., Kilbey A., Jenkins A., Herzyk P., Cameron E., et al. Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival. Oncogene 2008, 27:5856-5866.
    • (2008) Oncogene , vol.27 , pp. 5856-5866
    • Wotton, S.1    Terry, A.2    Kilbey, A.3    Jenkins, A.4    Herzyk, P.5    Cameron, E.6
  • 53
    • 39749132308 scopus 로고    scopus 로고
    • Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronicosteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial
    • Black L.L., Gaynor J., Gahring D., Adams C., Aron D., Harman S., et al. Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronicosteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial. Vet Ther 2007, 8:272-284.
    • (2007) Vet Ther , vol.8 , pp. 272-284
    • Black, L.L.1    Gaynor, J.2    Gahring, D.3    Adams, C.4    Aron, D.5    Harman, S.6
  • 54
    • 53949116759 scopus 로고    scopus 로고
    • Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs
    • Black L.L., Gaynor J., Adams C., Dhupa S., Sams A.E., Taylor R., et al. Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs. Vet Ther 2008, 9:192-200.
    • (2008) Vet Ther , vol.9 , pp. 192-200
    • Black, L.L.1    Gaynor, J.2    Adams, C.3    Dhupa, S.4    Sams, A.E.5    Taylor, R.6
  • 55
    • 78751667112 scopus 로고    scopus 로고
    • Therapeutic potentials of mesenchymal stem cells derived from human umbilical cord
    • Fan C.G., Zhang Q.J., Zhou J.R. Therapeutic potentials of mesenchymal stem cells derived from human umbilical cord. Stem Cell Rev 2011, 7:195-207.
    • (2011) Stem Cell Rev , vol.7 , pp. 195-207
    • Fan, C.G.1    Zhang, Q.J.2    Zhou, J.R.3
  • 56
    • 68749116404 scopus 로고    scopus 로고
    • A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering
    • Wang L., Tran I., Seshareddy K., Weiss M.L., Detamore M.S. A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering. Tissue Eng Part A 2009, 15:2259-2266.
    • (2009) Tissue Eng Part A , vol.15 , pp. 2259-2266
    • Wang, L.1    Tran, I.2    Seshareddy, K.3    Weiss, M.L.4    Detamore, M.S.5
  • 57
    • 84857653324 scopus 로고    scopus 로고
    • Human umbilical cord Wharton's jelly stem cells undergo enhanced chondrogenic differentiation when grown on nanofibrous scaffolds and in a sequential two-stage culture medium environment
    • Fong C.Y., Subramanian A., Gauthaman K., Venugopal J., Biswas A., Ramakrishna S., et al. Human umbilical cord Wharton's jelly stem cells undergo enhanced chondrogenic differentiation when grown on nanofibrous scaffolds and in a sequential two-stage culture medium environment. Stem Cell Rev 2012, 8:195-209.
    • (2012) Stem Cell Rev , vol.8 , pp. 195-209
    • Fong, C.Y.1    Subramanian, A.2    Gauthaman, K.3    Venugopal, J.4    Biswas, A.5    Ramakrishna, S.6
  • 58
    • 0036184589 scopus 로고    scopus 로고
    • Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees
    • Wakitani S., Imoto K., Yamamoto T., Saito M., Murata N., Yoneda M. Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritis Cartilage 2002, 10:199-206.
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 199-206
    • Wakitani, S.1    Imoto, K.2    Yamamoto, T.3    Saito, M.4    Murata, N.5    Yoneda, M.6
  • 59
    • 79959959344 scopus 로고    scopus 로고
    • Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series
    • Pak J. Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series. J Med Case Rep 2011, 5:296.
    • (2011) J Med Case Rep , vol.5 , pp. 296
    • Pak, J.1
  • 60
    • 84855172814 scopus 로고    scopus 로고
    • The pathogenesis of rheumatoid arthritis
    • McInnes I.B., Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med 2011, 365:2205-2219.
    • (2011) N Engl J Med , vol.365 , pp. 2205-2219
    • McInnes, I.B.1    Schett, G.2
  • 61
    • 64349116001 scopus 로고    scopus 로고
    • Chondrogenic potential of mesenchymal stem cells from patients with rheumatoid arthritis and osteoarthritis: measurements in a microculture system
    • Dudics V., Kunstár A., Kovács J., Lakatos T., Géher P., Gömör B., et al. Chondrogenic potential of mesenchymal stem cells from patients with rheumatoid arthritis and osteoarthritis: measurements in a microculture system. Cells Tissues Organs 2009, 189:307-316.
    • (2009) Cells Tissues Organs , vol.189 , pp. 307-316
    • Dudics, V.1    Kunstár, A.2    Kovács, J.3    Lakatos, T.4    Géher, P.5    Gömör, B.6
  • 62
    • 75749128260 scopus 로고    scopus 로고
    • Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level
    • Jones E., Churchman S.M., English A., Buch M.H., Horner E.A., Burgoyne C.H., et al. Mesenchymal stem cells in rheumatoid synovium: enumeration and functional assessment in relation to synovial inflammation level. Ann Rheum Dis 2010, 69:450-457.
    • (2010) Ann Rheum Dis , vol.69 , pp. 450-457
    • Jones, E.1    Churchman, S.M.2    English, A.3    Buch, M.H.4    Horner, E.A.5    Burgoyne, C.H.6
  • 63
    • 0036172594 scopus 로고    scopus 로고
    • Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritis
    • Marinova-Mutafchieva L., Williams R.O., Funa K., Maini R.N., Zvaifler N.J. Inflammation is preceded by tumor necrosis factor-dependent infiltration of mesenchymal cells in experimental arthritis. Arthritis Rheum 2002, 46:507-513.
    • (2002) Arthritis Rheum , vol.46 , pp. 507-513
    • Marinova-Mutafchieva, L.1    Williams, R.O.2    Funa, K.3    Maini, R.N.4    Zvaifler, N.J.5
  • 64
    • 33751238522 scopus 로고    scopus 로고
    • An essential role of NF-kappaB in the "tumor-like" phenotype of arthritic synoviocytes
    • Li X., Makarov S.S. An essential role of NF-kappaB in the "tumor-like" phenotype of arthritic synoviocytes. Proc Natl Acad Sci USA 2006, 103:17432-17437.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17432-17437
    • Li, X.1    Makarov, S.S.2
  • 65
    • 18644370435 scopus 로고    scopus 로고
    • Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis
    • Djouad F., Fritz V., Apparailly F., Louis-Plence P., Bony C., Sany J., et al. Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum 2005, 52:1595-1603.
    • (2005) Arthritis Rheum , vol.52 , pp. 1595-1603
    • Djouad, F.1    Fritz, V.2    Apparailly, F.3    Louis-Plence, P.4    Bony, C.5    Sany, J.6
  • 66
    • 34247231682 scopus 로고    scopus 로고
    • Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis
    • Augello A., Tasso R., Negrini S.M., Cancedda R., Pennesi G. Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum 2007, 56:1175-1186.
    • (2007) Arthritis Rheum , vol.56 , pp. 1175-1186
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3    Cancedda, R.4    Pennesi, G.5
  • 67
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • González M.A., Gonzalez-Rey E., Rico L., Büscher D., Delgado M. Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum 2009, 60:1006-1019.
    • (2009) Arthritis Rheum , vol.60 , pp. 1006-1019
    • González, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Büscher, D.4    Delgado, M.5
  • 68
    • 33750559121 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease
    • Yañez R., Lamana M.L., García-Castro J., Colmenero I., Ramírez M., Bueren J.A. Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells 2006, 24:2582-2591.
    • (2006) Stem Cells , vol.24 , pp. 2582-2591
    • Yañez, R.1    Lamana, M.L.2    García-Castro, J.3    Colmenero, I.4    Ramírez, M.5    Bueren, J.A.6
  • 69
    • 74549151228 scopus 로고    scopus 로고
    • Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6
    • Chen B., Hu J., Liao L., Sun Z., Han Q., Song Z., et al. Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6. Clin Exp Immunol 2010, 159:292-302.
    • (2010) Clin Exp Immunol , vol.159 , pp. 292-302
    • Chen, B.1    Hu, J.2    Liao, L.3    Sun, Z.4    Han, Q.5    Song, Z.6
  • 70
    • 77649298684 scopus 로고    scopus 로고
    • Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
    • Schurgers E., Kelchtermans H., Mitera T., Geboes L., Matthys P. Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. Arthritis Res Ther 2010, 12:R31.
    • (2010) Arthritis Res Ther , vol.12 , pp. R31
    • Schurgers, E.1    Kelchtermans, H.2    Mitera, T.3    Geboes, L.4    Matthys, P.5
  • 71
    • 73449133395 scopus 로고    scopus 로고
    • Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis
    • Gonzalez-Rey E., Gonzalez M.A., Varela N., O'Valle F., Hernandez-Cortes P., Rico L., et al. Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis. Ann Rheum Dis 2010, 69:241-248.
    • (2010) Ann Rheum Dis , vol.69 , pp. 241-248
    • Gonzalez-Rey, E.1    Gonzalez, M.A.2    Varela, N.3    O'Valle, F.4    Hernandez-Cortes, P.5    Rico, L.6
  • 72
    • 79958060173 scopus 로고    scopus 로고
    • Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis
    • Park M.J., Park H.S., Cho M.L., Oh H.J., Cho Y.G., Min S.Y., et al. Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis. Arthritis Rheum 2011, 63:1668-1680.
    • (2011) Arthritis Rheum , vol.63 , pp. 1668-1680
    • Park, M.J.1    Park, H.S.2    Cho, M.L.3    Oh, H.J.4    Cho, Y.G.5    Min, S.Y.6
  • 73
    • 78149495146 scopus 로고    scopus 로고
    • Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis
    • Liu Y., Mu R., Wang S., Long L., Liu X., Li R., et al. Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis. Arthritis Res Ther 2010, 12:R210.
    • (2010) Arthritis Res Ther , vol.12 , pp. R210
    • Liu, Y.1    Mu, R.2    Wang, S.3    Long, L.4    Liu, X.5    Li, R.6
  • 74
    • 84903761959 scopus 로고    scopus 로고
    • Mesenchymal stem cells, autoimmunity and rheumatoid arthritis
    • El-Jawhari J.J., El-Sherbiny Y.M., Jones E.A., McGonagle D. Mesenchymal stem cells, autoimmunity and rheumatoid arthritis. QJM 2014, 107:505-514.
    • (2014) QJM , vol.107 , pp. 505-514
    • El-Jawhari, J.J.1    El-Sherbiny, Y.M.2    Jones, E.A.3    McGonagle, D.4
  • 75
    • 24144491372 scopus 로고    scopus 로고
    • The relationship between initial clinical manifestation and long-term prognosis of patients with systemic lupus erythematosus
    • Tokano Y., Morimoto S., Amano H., Kawanishi T., Yano T., Tomyo M., et al. The relationship between initial clinical manifestation and long-term prognosis of patients with systemic lupus erythematosus. Mod Rheumatol 2005, 15:275-282.
    • (2005) Mod Rheumatol , vol.15 , pp. 275-282
    • Tokano, Y.1    Morimoto, S.2    Amano, H.3    Kawanishi, T.4    Yano, T.5    Tomyo, M.6
  • 76
    • 0032953105 scopus 로고    scopus 로고
    • Morbidity and mortality in systemic lupus erythematosus during a 5-year period. A multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus
    • Cervera R., Khamashta M.A., Font J., Sebastiani G.D., Gil A., Lavilla P., et al. Morbidity and mortality in systemic lupus erythematosus during a 5-year period. A multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus. Medicine (Baltimore) 1999, 78:167-175.
    • (1999) Medicine (Baltimore) , vol.78 , pp. 167-175
    • Cervera, R.1    Khamashta, M.A.2    Font, J.3    Sebastiani, G.D.4    Gil, A.5    Lavilla, P.6
  • 79
    • 84879336866 scopus 로고    scopus 로고
    • Hematopoietic and mesenchymal stem cell transplantation for severe and refractory systemic lupus erythematosus
    • Sui W., Hou X., Che W., Chen J., Ou M., Xue W., et al. Hematopoietic and mesenchymal stem cell transplantation for severe and refractory systemic lupus erythematosus. Clin Immunol 2013, 148:186-197.
    • (2013) Clin Immunol , vol.148 , pp. 186-197
    • Sui, W.1    Hou, X.2    Che, W.3    Chen, J.4    Ou, M.5    Xue, W.6
  • 80
    • 33847374613 scopus 로고    scopus 로고
    • Abnormality of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus
    • Sun L.Y., Zhang H.Y., Feng X.B., Hou Y.Y., Lu L.W., Fan L.M. Abnormality of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Lupus 2007, 16:121-128.
    • (2007) Lupus , vol.16 , pp. 121-128
    • Sun, L.Y.1    Zhang, H.Y.2    Feng, X.B.3    Hou, Y.Y.4    Lu, L.W.5    Fan, L.M.6
  • 81
    • 84866095966 scopus 로고    scopus 로고
    • Gene expression profile reveals abnormalities of multiple signaling pathways in mesenchymal stem cell derived from patients with systemic lupus erythematosus
    • Tang Y., Ma X., Zhang H., Gu Z., Hou Y., Gilkeson G.S., et al. Gene expression profile reveals abnormalities of multiple signaling pathways in mesenchymal stem cell derived from patients with systemic lupus erythematosus. Clin Dev Immunol 2012, 2012:826182.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 826182
    • Tang, Y.1    Ma, X.2    Zhang, H.3    Gu, Z.4    Hou, Y.5    Gilkeson, G.S.6
  • 82
    • 84865620125 scopus 로고    scopus 로고
    • Upregulation of p16INK4A promotes cellular senescence of bone marrow-derived mesenchymal stem cells from systemic lupus erythematosus patients
    • Gu Z., Cao X., Jiang J., Li L., Da Z., Liu H., et al. Upregulation of p16INK4A promotes cellular senescence of bone marrow-derived mesenchymal stem cells from systemic lupus erythematosus patients. Cell Signal 2012, 24:2307-2314.
    • (2012) Cell Signal , vol.24 , pp. 2307-2314
    • Gu, Z.1    Cao, X.2    Jiang, J.3    Li, L.4    Da, Z.5    Liu, H.6
  • 83
    • 77952921223 scopus 로고    scopus 로고
    • Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus
    • Nie Y., Lau C., Lie A., Chan G., Mok M. Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus. Lupus 2010, 19:850-859.
    • (2010) Lupus , vol.19 , pp. 850-859
    • Nie, Y.1    Lau, C.2    Lie, A.3    Chan, G.4    Mok, M.5
  • 84
    • 0034772643 scopus 로고    scopus 로고
    • Increased apoptosis of bone marrow CD34(+) cells and impaired function of bone marrow stromal cells in patients with systemic lupus erythematosus
    • Papadaki H.A., Boumpas D.T., Gibson F.M., Jayne D.R., Axford J.S., Gordon-Smith E.C., et al. Increased apoptosis of bone marrow CD34(+) cells and impaired function of bone marrow stromal cells in patients with systemic lupus erythematosus. Br J Haematol 2001, 115:167-174.
    • (2001) Br J Haematol , vol.115 , pp. 167-174
    • Papadaki, H.A.1    Boumpas, D.T.2    Gibson, F.M.3    Jayne, D.R.4    Axford, J.S.5    Gordon-Smith, E.C.6
  • 85
    • 67649580309 scopus 로고    scopus 로고
    • Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells
    • Heo J.Y., Jing K., Song K.S., Seo K.S., Park J.H., Kim J.S., et al. Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells. Stem Cells 2009, 27:1455-1462.
    • (2009) Stem Cells , vol.27 , pp. 1455-1462
    • Heo, J.Y.1    Jing, K.2    Song, K.S.3    Seo, K.S.4    Park, J.H.5    Kim, J.S.6
  • 86
    • 33747595991 scopus 로고    scopus 로고
    • Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stromal cells in vitro
    • Ebert R., Ulmer M., Zeck S., Meissner-Weigl J., Schneider D., Stopper H., et al. Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stromal cells in vitro. Stem Cells 2006, 24:1226-1235.
    • (2006) Stem Cells , vol.24 , pp. 1226-1235
    • Ebert, R.1    Ulmer, M.2    Zeck, S.3    Meissner-Weigl, J.4    Schneider, D.5    Stopper, H.6
  • 87
    • 66549091971 scopus 로고    scopus 로고
    • Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals
    • Maeda K., Malykhin A., Teague-Weber B.N., Sun X.H., Farris A.D., Coggeshall K.M. Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. Blood 2009, 113:4534-4540.
    • (2009) Blood , vol.113 , pp. 4534-4540
    • Maeda, K.1    Malykhin, A.2    Teague-Weber, B.N.3    Sun, X.H.4    Farris, A.D.5    Coggeshall, K.M.6
  • 89
    • 34547201175 scopus 로고    scopus 로고
    • A novel function of interleukin-10 promoting self-renewal of hematopoietic stem cells
    • Kang Y.J., Yang S.J., Park G., Cho B., Min C.K., Kim T.Y., et al. A novel function of interleukin-10 promoting self-renewal of hematopoietic stem cells. Stem Cells 2007, 25:1814-1822.
    • (2007) Stem Cells , vol.25 , pp. 1814-1822
    • Kang, Y.J.1    Yang, S.J.2    Park, G.3    Cho, B.4    Min, C.K.5    Kim, T.Y.6
  • 90
    • 79961138056 scopus 로고    scopus 로고
    • Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors
    • Pronk C.J., Veiby O.P., Bryder D., Jacobsen S.E. Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors. J Exp Med 2011, 208:1563-1570.
    • (2011) J Exp Med , vol.208 , pp. 1563-1570
    • Pronk, C.J.1    Veiby, O.P.2    Bryder, D.3    Jacobsen, S.E.4
  • 91
    • 62449102751 scopus 로고    scopus 로고
    • Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice
    • Zhou K., Zhang H., Jin O., Feng X., Yao G., Hou Y., et al. Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice. Cell Mol Immunol 2008, 5:417-424.
    • (2008) Cell Mol Immunol , vol.5 , pp. 417-424
    • Zhou, K.1    Zhang, H.2    Jin, O.3    Feng, X.4    Yao, G.5    Hou, Y.6
  • 92
    • 67649604299 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans
    • Sun L., Akiyama K., Zhang H., Yamaza T., Hou Y., Zhao S., et al. Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans. Stem Cells 2009, 27:1421-1432.
    • (2009) Stem Cells , vol.27 , pp. 1421-1432
    • Sun, L.1    Akiyama, K.2    Zhang, H.3    Yamaza, T.4    Hou, Y.5    Zhao, S.6
  • 93
    • 84855267258 scopus 로고    scopus 로고
    • Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation
    • Choi E.W., Shin I.S., Park S.Y., Park J.H., Kim J.S., Yoon E.J., et al. Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation. Arthritis Rheum 2012, 64:243-253.
    • (2012) Arthritis Rheum , vol.64 , pp. 243-253
    • Choi, E.W.1    Shin, I.S.2    Park, S.Y.3    Park, J.H.4    Kim, J.S.5    Yoon, E.J.6
  • 94
    • 84867905846 scopus 로고    scopus 로고
    • Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice
    • Gu F., Molano I., Ruiz P., Sun L., Gilkeson G.S. Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice. Clin Immunol 2012, 145:142-152.
    • (2012) Clin Immunol , vol.145 , pp. 142-152
    • Gu, F.1    Molano, I.2    Ruiz, P.3    Sun, L.4    Gilkeson, G.S.5
  • 95
    • 84879160785 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years experience
    • Wang D., Zhang H., Liang J., Li X., Feng X., Wang H., et al. Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years experience. Cell Transplant 2013, 22:2267-2277.
    • (2013) Cell Transplant , vol.22 , pp. 2267-2277
    • Wang, D.1    Zhang, H.2    Liang, J.3    Li, X.4    Feng, X.5    Wang, H.6
  • 96
    • 77749279645 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell treatment increased T regulatory cells with no effect on disease activity in two systemic lupus erythematosus patients
    • Carrion F., Nova E., Ruiz C., Diaz F., Inostroza C., Rojo D., et al. Autologous mesenchymal stem cell treatment increased T regulatory cells with no effect on disease activity in two systemic lupus erythematosus patients. Lupus 2010, 19:317-322.
    • (2010) Lupus , vol.19 , pp. 317-322
    • Carrion, F.1    Nova, E.2    Ruiz, C.3    Diaz, F.4    Inostroza, C.5    Rojo, D.6
  • 97
    • 84881361471 scopus 로고    scopus 로고
    • Review: evidence that systemic sclerosis is a vascular disease
    • Matucci-Cerinic M., Kahaleh B., Wigley F.M. Review: evidence that systemic sclerosis is a vascular disease. Arthritis Rheum 2013, 65:1953-1962.
    • (2013) Arthritis Rheum , vol.65 , pp. 1953-1962
    • Matucci-Cerinic, M.1    Kahaleh, B.2    Wigley, F.M.3
  • 98
    • 41849133613 scopus 로고    scopus 로고
    • Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosis
    • Larghero J., Farge D., Braccini A., Lecourt S., Scherberich A., Foïs E., et al. Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosis. Ann Rheum Dis 2008, 67:443-449.
    • (2008) Ann Rheum Dis , vol.67 , pp. 443-449
    • Larghero, J.1    Farge, D.2    Braccini, A.3    Lecourt, S.4    Scherberich, A.5    Foïs, E.6
  • 99
    • 34447520313 scopus 로고    scopus 로고
    • Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis
    • Cipriani P., Guiducci S., Miniati I., Cinelli M., Urbani S., Marrelli A., et al. Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis. Arthritis Rheum 2007, 56:1994-2004.
    • (2007) Arthritis Rheum , vol.56 , pp. 1994-2004
    • Cipriani, P.1    Guiducci, S.2    Miniati, I.3    Cinelli, M.4    Urbani, S.5    Marrelli, A.6
  • 101
    • 84879240261 scopus 로고    scopus 로고
    • Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine
    • Cipriani P., Marrelli A., Benedetto P.D., Liakouli V., Carubbi F., Ruscitti P., et al. Scleroderma Mesenchymal Stem Cells display a different phenotype from healthy controls; implications for regenerative medicine. Angiogenesis 2013, 16:595-607.
    • (2013) Angiogenesis , vol.16 , pp. 595-607
    • Cipriani, P.1    Marrelli, A.2    Benedetto, P.D.3    Liakouli, V.4    Carubbi, F.5    Ruscitti, P.6
  • 102
    • 80053560934 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells from early diffuse systemic sclerosis exhibit a paracrine machinery and stimulate angiogenesis in vitro
    • Guiducci S., Manetti M., Romano E., Mazzanti B., Ceccarelli C., Dal Pozzo S., et al. Bone marrow-derived mesenchymal stem cells from early diffuse systemic sclerosis exhibit a paracrine machinery and stimulate angiogenesis in vitro. Ann Rheum Dis 2011, 70:2011-2021.
    • (2011) Ann Rheum Dis , vol.70 , pp. 2011-2021
    • Guiducci, S.1    Manetti, M.2    Romano, E.3    Mazzanti, B.4    Ceccarelli, C.5    Dal Pozzo, S.6
  • 103
    • 84880032316 scopus 로고    scopus 로고
    • Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy
    • Cipriani P., Di Benedetto P., Liakouli V., Del Papa B., Di Padova M., Di Ianni M., et al. Mesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy. Clin Exp Immunol 2013, 173:195-206.
    • (2013) Clin Exp Immunol , vol.173 , pp. 195-206
    • Cipriani, P.1    Di Benedetto, P.2    Liakouli, V.3    Del Papa, B.4    Di Padova, M.5    Di Ianni, M.6
  • 104
    • 43749115968 scopus 로고    scopus 로고
    • Marked improvement of severe progressive systemic sclerosis after transplantation of mesenchymal stem cells from an allogeneic haploidentical-related donor mediated by ligation of CD137L
    • Christopeit M., Schendel M., Föll J., Müller L.P., Keysser G., Behre G. Marked improvement of severe progressive systemic sclerosis after transplantation of mesenchymal stem cells from an allogeneic haploidentical-related donor mediated by ligation of CD137L. Leukemia 2008, 22:1062-1064.
    • (2008) Leukemia , vol.22 , pp. 1062-1064
    • Christopeit, M.1    Schendel, M.2    Föll, J.3    Müller, L.P.4    Keysser, G.5    Behre, G.6
  • 105
    • 78751686638 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cells foster revascularization of ischemic limbs in systemic sclerosis: a case report
    • Guiducci S., Porta F., Saccardi R., Guidi S., Ibba-Manneschi L., Manetti M., et al. Autologous mesenchymal stem cells foster revascularization of ischemic limbs in systemic sclerosis: a case report. Ann Intern Med 2010, 153:650-654.
    • (2010) Ann Intern Med , vol.153 , pp. 650-654
    • Guiducci, S.1    Porta, F.2    Saccardi, R.3    Guidi, S.4    Ibba-Manneschi, L.5    Manetti, M.6
  • 106
    • 79961119978 scopus 로고    scopus 로고
    • Treatment of severe progressive systemic sclerosis with transplantation of mesenchymal stromal cells from allogeneic related donors: report of five cases
    • Keyszer G., Christopeit M., Fick S., Schendel M., Taute B.M., Behre G., et al. Treatment of severe progressive systemic sclerosis with transplantation of mesenchymal stromal cells from allogeneic related donors: report of five cases. Arthritis Rheum 2011, 63:2540-2542.
    • (2011) Arthritis Rheum , vol.63 , pp. 2540-2542
    • Keyszer, G.1    Christopeit, M.2    Fick, S.3    Schendel, M.4    Taute, B.M.5    Behre, G.6
  • 107
    • 84876353108 scopus 로고    scopus 로고
    • Human adipose-derived stromal cells for cell-based therapies in the treatment of systemic sclerosis
    • Scuderi N., Ceccarelli S., Onesti M.G., Fioramonti P., Guidi C., Romano F., et al. Human adipose-derived stromal cells for cell-based therapies in the treatment of systemic sclerosis. Cell Transplant 2013, 22:779-795.
    • (2013) Cell Transplant , vol.22 , pp. 779-795
    • Scuderi, N.1    Ceccarelli, S.2    Onesti, M.G.3    Fioramonti, P.4    Guidi, C.5    Romano, F.6
  • 108
    • 84875009952 scopus 로고    scopus 로고
    • Update on stem cell transplantation for systemic sclerosis: recent trial results
    • Naraghi K., van Laar J.M. Update on stem cell transplantation for systemic sclerosis: recent trial results. Curr Rheumatol Rep 2013, 15:326.
    • (2013) Curr Rheumatol Rep , vol.15 , pp. 326
    • Naraghi, K.1    van Laar, J.M.2
  • 109
    • 0025777221 scopus 로고
    • Osteogenesis imperfecta: translation of mutation to phenotype
    • Byers P.H., Wallis G.A., Willing M.C. Osteogenesis imperfecta: translation of mutation to phenotype. J Med Genet 1991, 28:433-442.
    • (1991) J Med Genet , vol.28 , pp. 433-442
    • Byers, P.H.1    Wallis, G.A.2    Willing, M.C.3
  • 110
    • 1842487509 scopus 로고    scopus 로고
    • High proportion of mutant osteoblasts is compatible with normal skeletal function in mosaic carriers of osteogenesis imperfecta
    • Cabral W.A., Marini J.C. High proportion of mutant osteoblasts is compatible with normal skeletal function in mosaic carriers of osteogenesis imperfecta. Am J Hum Genet 2004, 74:752-760.
    • (2004) Am J Hum Genet , vol.74 , pp. 752-760
    • Cabral, W.A.1    Marini, J.C.2
  • 111
    • 0032477883 scopus 로고    scopus 로고
    • Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
    • Pereira R.F., O'Hara M.D., Laptev A.V., Halford K.W., Pollard M.D., Class R., et al. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proc Natl Acad Sci USA 1998, 95:1142-1147.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1142-1147
    • Pereira, R.F.1    O'Hara, M.D.2    Laptev, A.V.3    Halford, K.W.4    Pollard, M.D.5    Class, R.6
  • 112
    • 38949106568 scopus 로고    scopus 로고
    • Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice
    • Guillot P.V., Abass O., Bassett J.H., Shefelbine S.J., Bou-Gharios G., Chan J., et al. Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice. Blood 2008, 111:1717-1725.
    • (2008) Blood , vol.111 , pp. 1717-1725
    • Guillot, P.V.1    Abass, O.2    Bassett, J.H.3    Shefelbine, S.J.4    Bou-Gharios, G.5    Chan, J.6
  • 113
    • 0002624625 scopus 로고
    • Osteogenesis imperfecta, rehabilitation medicine, fundamental research and mesenchymal stem cells
    • Caplan A.I. Osteogenesis imperfecta, rehabilitation medicine, fundamental research and mesenchymal stem cells. Connect Tissue Res 1995, 31:S9-14.
    • (1995) Connect Tissue Res , vol.31 , pp. S9-14
    • Caplan, A.I.1
  • 114
    • 0032976690 scopus 로고    scopus 로고
    • Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
    • Horwitz E.M., Prockop D.J., Fitzpatrick L.A., Koo W.W., Gordon P.L., Neel M., et al. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 1999, 5:309-313.
    • (1999) Nat Med , vol.5 , pp. 309-313
    • Horwitz, E.M.1    Prockop, D.J.2    Fitzpatrick, L.A.3    Koo, W.W.4    Gordon, P.L.5    Neel, M.6
  • 115
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • Horwitz E.M., Gordon P.L., Koo W.K., Marx J.C., Neel M.D., McNall R.Y., et al. Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone. Proc Natl Acad Sci USA 2002, 99:8932-8937.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8932-8937
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3    Marx, J.C.4    Neel, M.D.5    McNall, R.Y.6
  • 116
    • 20544455396 scopus 로고    scopus 로고
    • Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta
    • Le Blanc K., Götherström C., Ringdén O., Hassan M., McMahon R., Horwitz E., et al. Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta. Transplantation 2005, 79:1607-1614.
    • (2005) Transplantation , vol.79 , pp. 1607-1614
    • Le Blanc, K.1    Götherström, C.2    Ringdén, O.3    Hassan, M.4    McMahon, R.5    Horwitz, E.6
  • 118
    • 84857487154 scopus 로고    scopus 로고
    • Current management options for osteonecrosis of the femoral head: part 1, diagnosis and nonoperative management
    • Amanatullah D.F., Strauss E.J., Di Cesare P.E. Current management options for osteonecrosis of the femoral head: part 1, diagnosis and nonoperative management. Am J Orthop (Belle Mead NJ) 2011, 40:E186-E192.
    • (2011) Am J Orthop (Belle Mead NJ) , vol.40 , pp. E186-E192
    • Amanatullah, D.F.1    Strauss, E.J.2    Di Cesare, P.E.3
  • 119
    • 84862248439 scopus 로고    scopus 로고
    • Current management options for osteonecrosis of the femoral head: part II, operative management
    • Amanatullah D.F., Strauss E.J., Di Cesare P.E. Current management options for osteonecrosis of the femoral head: part II, operative management. Am J Orthop (Belle Mead NJ) 2011, 40:E216-E225.
    • (2011) Am J Orthop (Belle Mead NJ) , vol.40 , pp. E216-E225
    • Amanatullah, D.F.1    Strauss, E.J.2    Di Cesare, P.E.3
  • 120
    • 41849090064 scopus 로고    scopus 로고
    • Regenerative effects of transplanting autologous mesenchymal stem cells on corticosteroid-induced osteonecrosis in rabbits
    • Matsuya H., Kushida T., Asada T., Umeda M., Wada T., Iida H. Regenerative effects of transplanting autologous mesenchymal stem cells on corticosteroid-induced osteonecrosis in rabbits. Mod Rheumatol 2008, 18:132-139.
    • (2008) Mod Rheumatol , vol.18 , pp. 132-139
    • Matsuya, H.1    Kushida, T.2    Asada, T.3    Umeda, M.4    Wada, T.5    Iida, H.6
  • 121
    • 63349107849 scopus 로고    scopus 로고
    • Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head
    • Yan Z., Hang D., Guo C., Chen Z. Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head. J Orthop Res 2009, 27:442-446.
    • (2009) J Orthop Res , vol.27 , pp. 442-446
    • Yan, Z.1    Hang, D.2    Guo, C.3    Chen, Z.4
  • 122
    • 78651080413 scopus 로고    scopus 로고
    • Micro-CT-based bone ceramic scaffolding and its performance after seeding with mesenchymal stem cells for repair of load-bearing bone defect in canine femoral head
    • Peng J., Wen C., Wang A., Wang Y., Xu W., Zhao B., et al. Micro-CT-based bone ceramic scaffolding and its performance after seeding with mesenchymal stem cells for repair of load-bearing bone defect in canine femoral head. J Biomed Mater Res B Appl Biomater 2011, 96:316-325.
    • (2011) J Biomed Mater Res B Appl Biomater , vol.96 , pp. 316-325
    • Peng, J.1    Wen, C.2    Wang, A.3    Wang, Y.4    Xu, W.5    Zhao, B.6
  • 123
    • 77957682853 scopus 로고    scopus 로고
    • Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: preliminary results
    • Feitosa M.L., Fadel L., Beltrão-Braga P.C., Wenceslau C.V., Kerkis I., Kerkis A., et al. Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: preliminary results. Acta Cir Bras 2010, 25:416-422.
    • (2010) Acta Cir Bras , vol.25 , pp. 416-422
    • Feitosa, M.L.1    Fadel, L.2    Beltrão-Braga, P.C.3    Wenceslau, C.V.4    Kerkis, I.5    Kerkis, A.6
  • 124
    • 0036667101 scopus 로고    scopus 로고
    • Regenerative medicine through mesenchymal stem cells for bone and cartilage repair
    • Noël D., Djouad F., Jorgense C. Regenerative medicine through mesenchymal stem cells for bone and cartilage repair. Curr Opin Investig Drugs 2002, 3:1000-1004.
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 1000-1004
    • Noël, D.1    Djouad, F.2    Jorgense, C.3
  • 125
    • 74049118902 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy for nonmusculoskeletal diseases: emerging applications
    • Kuo T.K., Ho J.H., Lee O.K. Mesenchymal stem cell therapy for nonmusculoskeletal diseases: emerging applications. Cell Transplant 2009, 18:1013-1028.
    • (2009) Cell Transplant , vol.18 , pp. 1013-1028
    • Kuo, T.K.1    Ho, J.H.2    Lee, O.K.3
  • 126
    • 84861566211 scopus 로고    scopus 로고
    • Change in hepatocyte growth factor concentration promote mesenchymal stem cell-mediated osteogenic regeneration
    • Wen Q., Zhou L., Zhou C., Zhou M., Luo W., Ma L. Change in hepatocyte growth factor concentration promote mesenchymal stem cell-mediated osteogenic regeneration. J Cell Mol Med 2012, 16:1260-1273.
    • (2012) J Cell Mol Med , vol.16 , pp. 1260-1273
    • Wen, Q.1    Zhou, L.2    Zhou, C.3    Zhou, M.4    Luo, W.5    Ma, L.6
  • 127
    • 33846881606 scopus 로고    scopus 로고
    • Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats
    • Tang T.T., Lu B., Yue B., Xie X.H., Xie Y.Z., Dai K.R., et al. Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats. J Bone Joint Surg Br 2007, 89:127-129.
    • (2007) J Bone Joint Surg Br , vol.89 , pp. 127-129
    • Tang, T.T.1    Lu, B.2    Yue, B.3    Xie, X.H.4    Xie, Y.Z.5    Dai, K.R.6
  • 128
    • 0025968937 scopus 로고
    • MRI appearance of femoral head osteonecrosis following core decompression and bone grafting
    • Chan T.W., Dalinka M.K., Steinberg M.E., Kressel H.Y. MRI appearance of femoral head osteonecrosis following core decompression and bone grafting. Skeletal Radiol 1991, 20:103-107.
    • (1991) Skeletal Radiol , vol.20 , pp. 103-107
    • Chan, T.W.1    Dalinka, M.K.2    Steinberg, M.E.3    Kressel, H.Y.4
  • 129
    • 2642542690 scopus 로고    scopus 로고
    • Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study
    • Gangji V., Hauzeur J.P., Matos C., De Maertelaer V., Toungouz M., Lambermont M. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study. J Bone Joint Surg Am 2004, 86-A:1153-1160.
    • (2004) J Bone Joint Surg Am , pp. 1153-1160
    • Gangji, V.1    Hauzeur, J.P.2    Matos, C.3    De Maertelaer, V.4    Toungouz, M.5    Lambermont, M.6
  • 130
    • 77955466134 scopus 로고    scopus 로고
    • Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells
    • Wang B.L., Sun W., Shi Z.C., Zhang N.F., Yue D.B., Guo W.S., et al. Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells. Arch Orthop Trauma Surg 2010, 130:859-865.
    • (2010) Arch Orthop Trauma Surg , vol.130 , pp. 859-865
    • Wang, B.L.1    Sun, W.2    Shi, Z.C.3    Zhang, N.F.4    Yue, D.B.5    Guo, W.S.6
  • 131
    • 80054838532 scopus 로고    scopus 로고
    • Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: Five year follow-up of a prospective controlled study
    • Gangji V., De Maertelaer V., Hauzeur J.P. Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: Five year follow-up of a prospective controlled study. Bone 2011, 49:1005-1009.
    • (2011) Bone , vol.49 , pp. 1005-1009
    • Gangji, V.1    De Maertelaer, V.2    Hauzeur, J.P.3
  • 132
    • 82655170631 scopus 로고    scopus 로고
    • Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells
    • Zhao D., Cui D., Wang B., Tian F., Guo L., Yang L., et al. Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells. Bone 2012, 50:325-330.
    • (2012) Bone , vol.50 , pp. 325-330
    • Zhao, D.1    Cui, D.2    Wang, B.3    Tian, F.4    Guo, L.5    Yang, L.6
  • 133
    • 84856466024 scopus 로고    scopus 로고
    • Autologous adipose tissue-derived stem cells induce persistent bone-like tissue in osteonecrotic femoral heads
    • Pak J. Autologous adipose tissue-derived stem cells induce persistent bone-like tissue in osteonecrotic femoral heads. Pain Physician 2012, 15:75-85.
    • (2012) Pain Physician , vol.15 , pp. 75-85
    • Pak, J.1
  • 135
    • 70350550255 scopus 로고    scopus 로고
    • Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis
    • Dalle Carbonare L., Valenti M.T., Zanatta M., Donatelli L., Lo Cascio V. Circulating mesenchymal stem cells with abnormal osteogenic differentiation in patients with osteoporosis. Arthritis Rheum 2009, 60:3356-3365.
    • (2009) Arthritis Rheum , vol.60 , pp. 3356-3365
    • Dalle Carbonare, L.1    Valenti, M.T.2    Zanatta, M.3    Donatelli, L.4    Lo Cascio, V.5
  • 136
    • 65949113378 scopus 로고    scopus 로고
    • Marrow fat and the bone microenvironment: developmental, functional and pathological implications
    • Rosen C.J., Ackert-Bicknell C., Rodriguez J.P., Pino A.M. Marrow fat and the bone microenvironment: developmental, functional and pathological implications. Crit Rev Eukaryot Gene Expr 2009, 19:109-124.
    • (2009) Crit Rev Eukaryot Gene Expr , vol.19 , pp. 109-124
    • Rosen, C.J.1    Ackert-Bicknell, C.2    Rodriguez, J.P.3    Pino, A.M.4
  • 137
    • 0035010576 scopus 로고    scopus 로고
    • Number and proliferative capacity of osteogenic stem cells are maintained during aging and patients with osteoporosis
    • Stenderup K., Justesen J., Eriksen E.F., Rattan S.I.S., Kassem M. Number and proliferative capacity of osteogenic stem cells are maintained during aging and patients with osteoporosis. J Bone Miner Res 2001, 16:1120-1129.
    • (2001) J Bone Miner Res , vol.16 , pp. 1120-1129
    • Stenderup, K.1    Justesen, J.2    Eriksen, E.F.3    Rattan, S.I.S.4    Kassem, M.5
  • 138
    • 40349103527 scopus 로고    scopus 로고
    • Increased adipogenesis of osteoporotic human-mesenchymal stem cells (MSCs) is characterized by impaired leptin action
    • Astudillo P., Rios S., Pastenes L., Pino A.M., Rodriguez J.P. Increased adipogenesis of osteoporotic human-mesenchymal stem cells (MSCs) is characterized by impaired leptin action. J Cell Biochem 2008, 103:1054-1065.
    • (2008) J Cell Biochem , vol.103 , pp. 1054-1065
    • Astudillo, P.1    Rios, S.2    Pastenes, L.3    Pino, A.M.4    Rodriguez, J.P.5
  • 139
    • 0027973996 scopus 로고
    • Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy
    • Bruder S.P., Fink D.J., Caplan A.I. Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy. J Cell Biochem 1994, 56:283-294.
    • (1994) J Cell Biochem , vol.56 , pp. 283-294
    • Bruder, S.P.1    Fink, D.J.2    Caplan, A.I.3
  • 140
    • 33746736852 scopus 로고    scopus 로고
    • EH Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model
    • Wang Z., Goh J., De Das S., Ge Z., Ouyang H., Chong J.S., et al. EH Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model. Tissue Eng 2006, 12:1753-1761.
    • (2006) Tissue Eng , vol.12 , pp. 1753-1761
    • Wang, Z.1    Goh, J.2    De Das, S.3    Ge, Z.4    Ouyang, H.5    Chong, J.S.6
  • 141
    • 78049427750 scopus 로고    scopus 로고
    • Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats
    • Ocarino Nde M., Boeloni J.N., Jorgetti V., Gomes D.A., Goes A.M., Serakides R. Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats. Connect Tissue Res 2010, 51:426-433.
    • (2010) Connect Tissue Res , vol.51 , pp. 426-433
    • Ocarino Nde, M.1    Boeloni, J.N.2    Jorgetti, V.3    Gomes, D.A.4    Goes, A.M.5    Serakides, R.6
  • 142
    • 0031953736 scopus 로고    scopus 로고
    • Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders
    • Nuttall M.E., Patton A.J., Olivera D.J., Nadeau D.P., Gowen M. Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders. J Bone Miner Res 1998, 13:371-382.
    • (1998) J Bone Miner Res , vol.13 , pp. 371-382
    • Nuttall, M.E.1    Patton, A.J.2    Olivera, D.J.3    Nadeau, D.P.4    Gowen, M.5
  • 143
    • 77956022298 scopus 로고    scopus 로고
    • Is there a role for bone morphogenetic proteins in osteoporotic fractures?
    • Kanakaris N.K., Petsatodis G., Tagil M., Giannoudis P.V. Is there a role for bone morphogenetic proteins in osteoporotic fractures?. Injury 2009, 40(Suppl 3):S21-S26.
    • (2009) Injury , vol.40 , pp. S21-S26
    • Kanakaris, N.K.1    Petsatodis, G.2    Tagil, M.3    Giannoudis, P.V.4
  • 144
    • 33749076721 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer of receptor activator of nuclear factor-kappaB-Fc prevents bone loss in ovariectomized mice
    • Kim D., Cho S.W., Her S.J., Yang J.Y., Kim S.W., Kim S.Y., et al. Retrovirus-mediated gene transfer of receptor activator of nuclear factor-kappaB-Fc prevents bone loss in ovariectomized mice. Stem Cells 2006, 24:1798-1805.
    • (2006) Stem Cells , vol.24 , pp. 1798-1805
    • Kim, D.1    Cho, S.W.2    Her, S.J.3    Yang, J.Y.4    Kim, S.W.5    Kim, S.Y.6
  • 145
    • 65949116788 scopus 로고    scopus 로고
    • Restoration of bone mass and strength in glucocorticoid-treated mice by systemic transplantation of CXCR4 and cbfa-1 coexpressing mesenchymal stem cells
    • Lien C.Y., Chih-Yuan Ho K., Lee O.K., Blunn G.W., Su Y. Restoration of bone mass and strength in glucocorticoid-treated mice by systemic transplantation of CXCR4 and cbfa-1 coexpressing mesenchymal stem cells. J Bone Miner Res 2009, 24:837-848.
    • (2009) J Bone Miner Res , vol.24 , pp. 837-848
    • Lien, C.Y.1    Chih-Yuan Ho, K.2    Lee, O.K.3    Blunn, G.W.4    Su, Y.5
  • 146
    • 84863136375 scopus 로고    scopus 로고
    • Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures
    • Chen H.T., Lee M.J., Chen C.H., Chuang S.C., Chang L.F., Ho M.L., et al. Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures. J Cell Mol Med 2012, 16:582-593.
    • (2012) J Cell Mol Med , vol.16 , pp. 582-593
    • Chen, H.T.1    Lee, M.J.2    Chen, C.H.3    Chuang, S.C.4    Chang, L.F.5    Ho, M.L.6
  • 147
    • 79959886032 scopus 로고    scopus 로고
    • Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology
    • Maumus M., Guérit D., Toupet K., Jorgensen C., Noël D. Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology. Stem Cell Res Ther 2011, 2:14.
    • (2011) Stem Cell Res Ther , vol.2 , pp. 14
    • Maumus, M.1    Guérit, D.2    Toupet, K.3    Jorgensen, C.4    Noël, D.5
  • 148
    • 84873900026 scopus 로고    scopus 로고
    • Anti-inflammatory role and immunomodulation of mesenchymal stem cells in systemic joint diseases: potential for treatment
    • MacFarlane R.J., Graham S.M., Davies P.S., Korres N., Tsouchnica H., Heliotis M., et al. Anti-inflammatory role and immunomodulation of mesenchymal stem cells in systemic joint diseases: potential for treatment. Expert Opin Ther Targets 2013, 17:243-254.
    • (2013) Expert Opin Ther Targets , vol.17 , pp. 243-254
    • MacFarlane, R.J.1    Graham, S.M.2    Davies, P.S.3    Korres, N.4    Tsouchnica, H.5    Heliotis, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.