메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages 13-24

Therapeutic application of mesenchymal stem cells in bone and joint diseases

Author keywords

Mesenchymal stem cells (MSCs); Osteoarthritis (OA); Osteogenesis imperfecta (OI); Osteonecrosis of the femoral head (ONFH); Osteoporosis; Rheumatoid arthritis (RA)

Indexed keywords

ANIMALS; BONE DISEASES; DISEASE MODELS, ANIMAL; HUMANS; JOINT DISEASES; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS;

EID: 84895171384     PISSN: 15918890     EISSN: 15919528     Source Type: Journal    
DOI: 10.1007/s10238-012-0218-1     Document Type: Review
Times cited : (77)

References (132)
  • 1
    • 84989485234 scopus 로고
    • The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells
    • Friedenstin AJ, Chailakhjan RK, Lalykina KS (1970) The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinetics 3:393-403
    • (1970) Cell Tissue Kinetics , vol.3 , pp. 393-403
    • Friedenstin, A.J.1    Chailakhjan, R.K.2    Lalykina, K.S.3
  • 2
    • 33745503987 scopus 로고    scopus 로고
    • Mesenchymal stem cells reside in virtually all post-natal organs and tissues
    • da Silva ML, Chagatelles PC, Nardi NB (2006) Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 119:2204-2213
    • (2006) J Cell Sci , vol.119 , pp. 2204-2213
    • Da Silva, M.L.1    Chagatelles, P.C.2    Nardi, N.B.3
  • 3
    • 0035889146 scopus 로고    scopus 로고
    • Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow
    • 1:CAS:528:DC%2BD3MXnslCqsr0%3D 11588036
    • Campagnoli C, Roberts IA, Kumar S, Bennett PR, Bellantuono I, Fisk NM (2001) Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood 98:2396-2402
    • (2001) Blood , vol.98 , pp. 2396-2402
    • Campagnoli, C.1    Roberts, I.A.2    Kumar, S.3    Bennett, P.R.4    Bellantuono, I.5    Fisk, N.M.6
  • 4
    • 77955653051 scopus 로고    scopus 로고
    • Application of human umbilical cord blood-derived mesenchymal stem cells in disease models
    • 3097922 21607114
    • Kim JY, Jeon HB, Yang YS, Oh W, Chang JW (2010) Application of human umbilical cord blood-derived mesenchymal stem cells in disease models. World J Stem Cells 2:34-38
    • (2010) World J Stem Cells , vol.2 , pp. 34-38
    • Kim, J.Y.1    Jeon, H.B.2    Yang, Y.S.3    Oh, W.4    Chang, J.W.5
  • 5
    • 14544305075 scopus 로고    scopus 로고
    • The human adipose tissue is a source of multipotent stem cells
    • 1:CAS:528:DC%2BD2MXhslCntb4%3D 15733747
    • Rodriguez AM, Elabd C, Amri EZ, Aihaud G, Dani C (2005) The human adipose tissue is a source of multipotent stem cells. Biochimie 87:125-128
    • (2005) Biochimie , vol.87 , pp. 125-128
    • Rodriguez, A.M.1    Elabd, C.2    Amri, E.Z.3    Aihaud, G.4    Dani, C.5
  • 6
    • 57649200642 scopus 로고    scopus 로고
    • Human fetal membranes: A source of stem cells for tissue regeneration and repair?
    • 1:CAS:528:DC%2BD1cXhsFamtbjO 18995896
    • Ilancheran S, Moodley Y, Manuelpillai U (2009) Human fetal membranes: a source of stem cells for tissue regeneration and repair? Placenta 30:2-10
    • (2009) Placenta , vol.30 , pp. 2-10
    • Ilancheran, S.1    Moodley, Y.2    Manuelpillai, U.3
  • 7
    • 47249146422 scopus 로고    scopus 로고
    • Immunological properties of umbilical cord blood-derived mesenchymal stromal cells
    • 1:CAS:528:DC%2BD1cXoslentb0%3D 18495100
    • Oh W, Kim DS, Yang YS, Lee JK (2008) Immunological properties of umbilical cord blood-derived mesenchymal stromal cells. Cell Immunol 251:116-123
    • (2008) Cell Immunol , vol.251 , pp. 116-123
    • Oh, W.1    Kim, D.S.2    Yang, Y.S.3    Lee, J.K.4
  • 8
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • 11986244
    • Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, Grisanti S, Gianni AM (2002) Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99:3838-3843
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 10
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induced T-cell unresponsiveness
    • 1:CAS:528:DC%2BD2MXitVOnt7c%3D 15514012
    • Beyth S, Borovsky Z, Mevorach D, Liebergall M, Gazit Z, Aslan H, Galun E, Rachmilewitz J (2005) Human mesenchymal stem cells alter antigen-presenting cell maturation and induced T-cell unresponsiveness. Blood 105:2214-2219
    • (2005) Blood , vol.105 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3    Liebergall, M.4    Gazit, Z.5    Aslan, H.6    Galun, E.7    Rachmilewitz, J.8
  • 11
    • 84866286844 scopus 로고    scopus 로고
    • Application for proteomic techniques in studying osteoarthritis: A review
    • 3228966 22144964
    • Gharbi M, Deberg M, Henrotin Y (2011) Application for proteomic techniques in studying osteoarthritis: a review. Front Physiol 2:90
    • (2011) Front Physiol , vol.2 , pp. 90
    • Gharbi, M.1    Deberg, M.2    Henrotin, Y.3
  • 12
    • 81055127626 scopus 로고    scopus 로고
    • Homing and reparative effect of intra-articular injection of autologous mesenchymal stem cells in osteoarthritic animal model
    • 1:CAS:528:DC%2BC38XhtFaku7c%3D
    • Mokbel AN, El Tookhy OS, Shamaa AA, Rashed LA, Sabry D, El Sayed AM (2011) Homing and reparative effect of intra-articular injection of autologous mesenchymal stem cells in osteoarthritic animal model. BMC Musculoskelet Discord 12:259
    • (2011) BMC Musculoskelet Discord , vol.12 , pp. 259
    • Mokbel, A.N.1    El Tookhy, O.S.2    Shamaa, A.A.3    Rashed, L.A.4    Sabry, D.5    El Sayed, A.M.6
  • 13
    • 4344604554 scopus 로고    scopus 로고
    • Aging theories of primary osteoarthritis: From epidemiology to molecular biology
    • 1:CAS:528:DC%2BD2cXntVyrs70%3D 15312300
    • Aigner T, Rose J, Martin J, Buckwalter J (2004) Aging theories of primary osteoarthritis: from epidemiology to molecular biology. Rejuvenation Res 7:134-145
    • (2004) Rejuvenation Res , vol.7 , pp. 134-145
    • Aigner, T.1    Rose, J.2    Martin, J.3    Buckwalter, J.4
  • 14
    • 84866279815 scopus 로고    scopus 로고
    • Applications of proteomics to osteoarthritis, a musculoskeletal disease characterized by aging
    • 3246359 22207853
    • Mobasheri A (2011) Applications of proteomics to osteoarthritis, a musculoskeletal disease characterized by aging. Front Physiol 2:108
    • (2011) Front Physiol , vol.2 , pp. 108
    • Mobasheri, A.1
  • 15
    • 47149103922 scopus 로고    scopus 로고
    • Technology Insight: Adult mesenchymal stem cells for osteoarthritis therapy: Delivery modes for Mesenchymal stem cells
    • 18477997
    • Nöth U, Steinert AF, Tuan RS (2008) Technology Insight: adult mesenchymal stem cells for osteoarthritis therapy: delivery modes for Mesenchymal stem cells. Nat Clin Pract Rheumatol 4:371-380
    • (2008) Nat Clin Pract Rheumatol , vol.4 , pp. 371-380
    • Nöth, U.1    Steinert, A.F.2    Tuan, R.S.3
  • 16
    • 33746886283 scopus 로고    scopus 로고
    • Animal models of osteoarthritis: Lessons learned while seeking the 'Holy Grail'
    • 16896297
    • Ameye LG, Young MF (2006) Animal models of osteoarthritis: lessons learned while seeking the 'Holy Grail'. Curr Opin Rheumatol 18:537-547
    • (2006) Curr Opin Rheumatol , vol.18 , pp. 537-547
    • Ameye, L.G.1    Young, M.F.2
  • 17
    • 33845940576 scopus 로고    scopus 로고
    • Osteochondral defect repair with autologous bone marrow-derived mesenchymal stem cells in an injectable, in situ, cross-linked synthetic extracellular matrix
    • 1:CAS:528:DC%2BD2sXhtVChtbY%3D 17518677
    • Liu Y, Shu XZ, Prestwich GD (2006) Osteochondral defect repair with autologous bone marrow-derived mesenchymal stem cells in an injectable, in situ, cross-linked synthetic extracellular matrix. Tissue Eng 12:3405-3416
    • (2006) Tissue Eng , vol.12 , pp. 3405-3416
    • Liu, Y.1    Shu, X.Z.2    Prestwich, G.D.3
  • 18
    • 19944429371 scopus 로고    scopus 로고
    • Repair of large articular cartilage defects with implants of autologous mesenchymal stem cells seeded into beta-tricalcium phosphate in a sheep model
    • 1:CAS:528:DC%2BD2MXhtVOru78%3D 15684690
    • Guo X, Wang X, Zhang Y, Xia R, Hu M, Duan C (2004) Repair of large articular cartilage defects with implants of autologous mesenchymal stem cells seeded into beta-tricalcium phosphate in a sheep model. Tissue Eng 10:1818-1829
    • (2004) Tissue Eng , vol.10 , pp. 1818-1829
    • Guo, X.1    Wang, X.2    Zhang, Y.3    Xia, R.4    Hu, M.5    Duan, C.6
  • 19
    • 3042757550 scopus 로고    scopus 로고
    • Treatment of chondral lesions in advanced osteochondritis dissecans: A comparative study of the efficacy of chondrocytes, mesenchymal stem cells, periosteal graft, and mosaicplasty (osteochondral autograft) in animal models
    • 15205626
    • Hui JHP, Chen F, Thambyah A, Lee EH (2004) Treatment of chondral lesions in advanced osteochondritis dissecans: a comparative study of the efficacy of chondrocytes, mesenchymal stem cells, periosteal graft, and mosaicplasty (osteochondral autograft) in animal models. J Pediatr Orthop 24:427-433
    • (2004) J Pediatr Orthop , vol.24 , pp. 427-433
    • Hui, J.H.P.1    Chen, F.2    Thambyah, A.3    Lee, E.H.4
  • 20
    • 33846630795 scopus 로고    scopus 로고
    • Repair of full-thickness cartilage defects with cells of different origin in a rabbit model
    • 17276226
    • Yan H, Yu C (2007) Repair of full-thickness cartilage defects with cells of different origin in a rabbit model. Arthroscopy 23:178-187
    • (2007) Arthroscopy , vol.23 , pp. 178-187
    • Yan, H.1    Yu, C.2
  • 21
    • 33747655031 scopus 로고    scopus 로고
    • Transplantation of autologous rabbit BM-derived mesenchymal stromal cells embedded in hyaluronic acid gel sponge into osteochondral defects of the knee
    • 1:CAS:528:DC%2BD28Xht1WjtL7P 16923610
    • Kayakabe M, Tsutsumi S, Watanabe H, Kato Y, Takagishi K (2006) Transplantation of autologous rabbit BM-derived mesenchymal stromal cells embedded in hyaluronic acid gel sponge into osteochondral defects of the knee. Cytotherapy 8:343-353
    • (2006) Cytotherapy , vol.8 , pp. 343-353
    • Kayakabe, M.1    Tsutsumi, S.2    Watanabe, H.3    Kato, Y.4    Takagishi, K.5
  • 22
    • 33846367391 scopus 로고    scopus 로고
    • Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone marrow stromal cells
    • 1:STN:280:DC%2BD2s%2FltF2ksQ%3D%3D 17002893
    • Kuroda R, Ishida K, Matsumoto T, Akisue T, Fujioka H, Mizuno K (2007) Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone marrow stromal cells. Osteoarthritis Cartilage 15:226-231
    • (2007) Osteoarthritis Cartilage , vol.15 , pp. 226-231
    • Kuroda, R.1    Ishida, K.2    Matsumoto, T.3    Akisue, T.4    Fujioka, H.5    Mizuno, K.6
  • 23
    • 36248974720 scopus 로고    scopus 로고
    • Injectable mesenchymal stem cell therapy for large cartilage defects-a porcine model
    • 17656639
    • Lee KBL, Hui JHP, Song IC, Ardany L, Lee EH (2007) Injectable mesenchymal stem cell therapy for large cartilage defects-a porcine model. Stem Cells 25:2964-2971
    • (2007) Stem Cells , vol.25 , pp. 2964-2971
    • Lee, K.B.L.1    Hui, J.H.P.2    Song, I.C.3    Ardany, L.4    Lee, E.H.5
  • 25
    • 81055127626 scopus 로고    scopus 로고
    • Homing and reparative effect of intra-articular injection of autologous mesenchymal stem cells in osteoarthritic animal model
    • 1:CAS:528:DC%2BC38XhtFaku7c%3D 3232438 22085445
    • Mokbel AN, El Tookhy OS, Shamaa AA, Rashed LA, Sabry D, El Sayed AM (2011) Homing and reparative effect of intra-articular injection of autologous mesenchymal stem cells in osteoarthritic animal model. BMC Musculoskelet Disord 12:259
    • (2011) BMC Musculoskelet Disord , vol.12 , pp. 259
    • Mokbel, A.N.1    El Tookhy, O.S.2    Shamaa, A.A.3    Rashed, L.A.4    Sabry, D.5    El Sayed, A.M.6
  • 26
    • 84856569681 scopus 로고    scopus 로고
    • Direct transplantation of mesenchymal stem cells into the knee joints of Hartley Strain guinea pig with spontaneous osteoarthritis
    • 1:CAS:528:DC%2BC38XnvFWktLw%3D 3392826 22314040
    • Sato M, Uchida K, Nakajima H, Miyazaki T, Guerrero AR, Watanabe S, Roberts S, Baba H (2012) Direct transplantation of mesenchymal stem cells into the knee joints of Hartley Strain guinea pig with spontaneous osteoarthritis. Arthritis Res Ther 14:R31
    • (2012) Arthritis Res Ther , vol.14 , pp. 31
    • Sato, M.1    Uchida, K.2    Nakajima, H.3    Miyazaki, T.4    Guerrero, A.R.5    Watanabe, S.6    Roberts, S.7    Baba, H.8
  • 27
    • 65649151921 scopus 로고    scopus 로고
    • Intra-articular injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization of distant organs in rat massive meniscal defect
    • 1:CAS:528:DC%2BD1MXmt1Wnsbs%3D 19350690
    • Horie M, Sekiya I, Muneta T, Ichinose S, Matsumoto K, Saito H, Murakami T, Kobayashi E (2009) Intra-articular injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization of distant organs in rat massive meniscal defect. Stem Cells 27:878-887
    • (2009) Stem Cells , vol.27 , pp. 878-887
    • Horie, M.1    Sekiya, I.2    Muneta, T.3    Ichinose, S.4    Matsumoto, K.5    Saito, H.6    Murakami, T.7    Kobayashi, E.8
  • 28
    • 65549095406 scopus 로고    scopus 로고
    • Synovium-derived mesenchymal stem cells: A new cell source for musculoskeletal regeneration
    • 1:CAS:528:DC%2BD1MXivVKisrw%3D 19196118
    • Fan J, Varshney RR, Ren L, Cai D, Wang DA (2009) Synovium-derived mesenchymal stem cells: a new cell source for musculoskeletal regeneration. Tissue Eng Part B Rev 15:75-86
    • (2009) Tissue Eng Part B Rev , vol.15 , pp. 75-86
    • Fan, J.1    Varshney, R.R.2    Ren, L.3    Cai, D.4    Wang, D.A.5
  • 30
    • 84859435828 scopus 로고    scopus 로고
    • Comparative investigation of the differentiation capability of bone-marrow-and adipose-derived mesenchymal stem cells by qualitative and quantitative analysis
    • 22287041
    • Vishnubalaji R, Al-Nbaheen M, Kadalmani B, Aldahmash A, Ramesh T (2012) Comparative investigation of the differentiation capability of bone-marrow-and adipose-derived mesenchymal stem cells by qualitative and quantitative analysis. Cell Tissue Res 347:419-427
    • (2012) Cell Tissue Res , vol.347 , pp. 419-427
    • Vishnubalaji, R.1    Al-Nbaheen, M.2    Kadalmani, B.3    Aldahmash, A.4    Ramesh, T.5
  • 31
    • 4644318975 scopus 로고    scopus 로고
    • Adipose-derived adult stem cells for cartilage tissue engineering
    • 1:CAS:528:DC%2BD2cXlvF2hsr4%3D 15299271
    • Guilak F, Awad HA, Fermor B, Leddy HA, Gimble JM (2004) Adipose-derived adult stem cells for cartilage tissue engineering. Biorheology 41:389-399
    • (2004) Biorheology , vol.41 , pp. 389-399
    • Guilak, F.1    Awad, H.A.2    Fermor, B.3    Leddy, H.A.4    Gimble, J.M.5
  • 32
    • 39749132308 scopus 로고    scopus 로고
    • Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: A randomized, double-blinded, multicenter, controlled trial
    • 18183546
    • Black LL, Gaynor J, Gahring D, Adams C, Aron D, Harman S, Gingerich DA, Harman R (2007) Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial. Veterinary Therapeutics 8:272-284
    • (2007) Veterinary Therapeutics , vol.8 , pp. 272-284
    • Black, L.L.1    Gaynor, J.2    Gahring, D.3    Adams, C.4    Aron, D.5    Harman, S.6    Gingerich, D.A.7    Harman, R.8
  • 33
    • 53949116759 scopus 로고    scopus 로고
    • Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs
    • 19003780
    • Black LL, Gaynor J, Adams C, Dhupa S, Sams AE, Taylor R, Harman S, Gingerich DA, Harman R (2008) Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs. Vet Ther 9:192-200
    • (2008) Vet Ther , vol.9 , pp. 192-200
    • Black, L.L.1    Gaynor, J.2    Adams, C.3    Dhupa, S.4    Sams, A.E.5    Taylor, R.6    Harman, S.7    Gingerich, D.A.8    Harman, R.9
  • 34
    • 70350500201 scopus 로고    scopus 로고
    • Umbilical cord Wharton's Jelly: A new potential cell source of mesenchymal stomal cells for bone tissue engineering
    • 1:CAS:528:DC%2BD1MXhtVKjs7fJ 19231937
    • Hou T, Xu J, Wu X, Xie Z, Luo F, Zhang Z, Zeng L (2009) Umbilical cord Wharton's Jelly: a new potential cell source of mesenchymal stomal cells for bone tissue engineering. Tissue Eng Part A 15:2325-2334
    • (2009) Tissue Eng Part A , vol.15 , pp. 2325-2334
    • Hou, T.1    Xu, J.2    Wu, X.3    Xie, Z.4    Luo, F.5    Zhang, Z.6    Zeng, L.7
  • 35
    • 78751667112 scopus 로고    scopus 로고
    • Therapeutic potentials of mesenchymal stem cells derived from human umbilical cord
    • 20676943
    • Fan CG, Zhang QJ, Zhou JR (2011) Therapeutic potentials of mesenchymal stem cells derived from human umbilical cord. Stem Cell Rev 7:195-207
    • (2011) Stem Cell Rev , vol.7 , pp. 195-207
    • Fan, C.G.1    Zhang, Q.J.2    Zhou, J.R.3
  • 36
    • 68749116404 scopus 로고    scopus 로고
    • A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering
    • 1:CAS:528:DC%2BD1MXhtVWnurzK 19260778
    • Wang L, Tran I, Seshareddy K, Weiss ML, Detamore MS (2009) A comparison of human bone marrow-derived mesenchymal stem cells and human umbilical cord-derived mesenchymal stromal cells for cartilage tissue engineering. Tissue Eng Part A 15:2259-2266
    • (2009) Tissue Eng Part A , vol.15 , pp. 2259-2266
    • Wang, L.1    Tran, I.2    Seshareddy, K.3    Weiss, M.L.4    Detamore, M.S.5
  • 37
    • 84857653324 scopus 로고    scopus 로고
    • Human umbilical cord Whaton's Jelly stem cells undergo enhanced chondrogenic differentiation when grown on nanofibrous scaffolds and in a sequential two-stage culture medium environment
    • 1:CAS:528:DC%2BC38XjtVCrtbc%3D 21671058
    • Fong CY, Subramanian A, Gauthaman K, Venugopal J, Biswas A, Ramakrishna S, Bongso A (2012) Human umbilical cord Whaton's Jelly stem cells undergo enhanced chondrogenic differentiation when grown on nanofibrous scaffolds and in a sequential two-stage culture medium environment. Stem Cell Rev 8:195-209
    • (2012) Stem Cell Rev , vol.8 , pp. 195-209
    • Fong, C.Y.1    Subramanian, A.2    Gauthaman, K.3    Venugopal, J.4    Biswas, A.5    Ramakrishna, S.6    Bongso, A.7
  • 38
    • 80052501430 scopus 로고    scopus 로고
    • Effect of dehydroepiandrosterone on aggrecanase expression in articular cartilage in a rabbit model of osteoarthritis
    • 1:CAS:528:DC%2BC3MXlsVGitr8%3D 21104136
    • Huang K, Zhang C, Zhang XW, Bao JP, Wu LD (2011) Effect of dehydroepiandrosterone on aggrecanase expression in articular cartilage in a rabbit model of osteoarthritis. Mol Biol Rep 38:3569-3572
    • (2011) Mol Biol Rep , vol.38 , pp. 3569-3572
    • Huang, K.1    Zhang, C.2    Zhang, X.W.3    Bao, J.P.4    Wu, L.D.5
  • 39
    • 0036184589 scopus 로고    scopus 로고
    • Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knee
    • 1:STN:280:DC%2BD387jsFegug%3D%3D 11869080
    • Wakitani S, Imoto K, Yamamoto T, Saito M, Murata N, Yoneda M (2002) Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knee. Osteoarthritis Cartilage 10:199-206
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 199-206
    • Wakitani, S.1    Imoto, K.2    Yamamoto, T.3    Saito, M.4    Murata, N.5    Yoneda, M.6
  • 40
    • 13944271410 scopus 로고    scopus 로고
    • Tissue engineered ceramic artificial joint-ex vivo osteogenic differentiation of patient mesenchymal cells on total ankle joints for treatment of osteoarthritis
    • 1:CAS:528:DC%2BD2MXhs1Gnsr8%3D 15722135
    • Ohgushi H, Kotobuki N, Funaoka H, Machida H, Hirose M, Tanaka Y, Takakura Y (2005) Tissue engineered ceramic artificial joint-ex vivo osteogenic differentiation of patient mesenchymal cells on total ankle joints for treatment of osteoarthritis. Biomaterials 26:4654-4661
    • (2005) Biomaterials , vol.26 , pp. 4654-4661
    • Ohgushi, H.1    Kotobuki, N.2    Funaoka, H.3    Machida, H.4    Hirose, M.5    Tanaka, Y.6    Takakura, Y.7
  • 41
    • 79959959344 scopus 로고    scopus 로고
    • Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: A case series
    • 3154169 21736710
    • Pak J (2011) Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series. J Med Case Rep 5:296
    • (2011) J Med Case Rep , vol.5 , pp. 296
    • Pak, J.1
  • 42
    • 46949103497 scopus 로고    scopus 로고
    • Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells
    • 18523506
    • Centeno CJ, Busse D, Kisiday J, Keohan C, Freeman M, Karli D (2008) Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells. Pain Physician 11:343-353
    • (2008) Pain Physician , vol.11 , pp. 343-353
    • Centeno, C.J.1    Busse, D.2    Kisiday, J.3    Keohan, C.4    Freeman, M.5    Karli, D.6
  • 43
    • 79955137985 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients
    • 21518322
    • Davatchi F, Abdollahi BS, Mohyeddin M, Shahram F, Nikbin B (2011) Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients. Int J Rheum Dis 14:211-215
    • (2011) Int J Rheum Dis , vol.14 , pp. 211-215
    • Davatchi, F.1    Abdollahi, B.S.2    Mohyeddin, M.3    Shahram, F.4    Nikbin, B.5
  • 44
    • 29244438790 scopus 로고    scopus 로고
    • Where do T cells stand in rheumatoid arthritis?
    • 16087382
    • Fournier C (2005) Where do T cells stand in rheumatoid arthritis? Joint Bone Spine 72:527-532
    • (2005) Joint Bone Spine , vol.72 , pp. 527-532
    • Fournier, C.1
  • 45
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • 1:CAS:528:DC%2BD3sXjs1ynu7c%3D 12748655
    • Firestein GS (2003) Evolving concepts of rheumatoid arthritis. Nature 423:356-361
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 46
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • 1:CAS:528:DC%2BD1MXltFenu7Y%3D 19333946
    • Gonzalez MA, Gonzalez-Rey E, Rico L, Buscher D, Delgado M (2009) Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum 60:1006-1019
    • (2009) Arthritis Rheum , vol.60 , pp. 1006-1019
    • Gonzalez, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Buscher, D.4    Delgado, M.5
  • 47
    • 0030970556 scopus 로고    scopus 로고
    • The role of T cells in the immunopathogenesis of rheumatoid arthritis: New perspectives
    • 1:STN:280:DyaK2s3ksVaqsA%3D%3D 9125240
    • Fox DA (1997) The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives. Arthritis Rheum 40:598-609
    • (1997) Arthritis Rheum , vol.40 , pp. 598-609
    • Fox, D.A.1
  • 48
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
    • 1:CAS:528:DC%2BD1cXitlygtb8%3D 18371435
    • Ren G, Zhang L, Zhao X, Xu G, Zhang Y, Roberts AI, Zhao RC, Shi Y (2008) Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2:141-150
    • (2008) Cell Stem Cell , vol.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3    Xu, G.4    Zhang, Y.5    Roberts, A.I.6    Zhao, R.C.7    Shi, Y.8
  • 49
    • 80052338976 scopus 로고    scopus 로고
    • Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases
    • MacDonal GI, Augello A, De Bari C (2011) Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases. Arthritis Rheum 63(9):2547-2557
    • (2011) Arthritis Rheum , vol.63 , Issue.9 , pp. 2547-2557
    • Macdonal, G.I.1    Augello, A.2    De Bari, C.3
  • 50
    • 18644370435 scopus 로고    scopus 로고
    • Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis
    • 1:CAS:528:DC%2BD2MXkvFCis78%3D 15880818
    • Djouad F, Fritz V, Apparailly F, Louis-Plence P, Bony C, Sany J, Jorgensen C, Noel D (2005) Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum 52:1595-1603
    • (2005) Arthritis Rheum , vol.52 , pp. 1595-1603
    • Djouad, F.1    Fritz, V.2    Apparailly, F.3    Louis-Plence, P.4    Bony, C.5    Sany, J.6    Jorgensen, C.7    Noel, D.8
  • 51
    • 77649298684 scopus 로고    scopus 로고
    • Discrepancy between the in vitro and in vivo effect of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
    • Schurgers E, Kelchtermans H, Mitera T, Geboes L, Matthys P (2010) Discrepancy between the in vitro and in vivo effect of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. Arthritis Res Therapy 12:R31
    • (2010) Arthritis Res Therapy , vol.12 , pp. 31
    • Schurgers, E.1    Kelchtermans, H.2    Mitera, T.3    Geboes, L.4    Matthys, P.5
  • 52
    • 74549151228 scopus 로고    scopus 로고
    • Flk-1 + mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6
    • 1:CAS:528:DC%2BC3cXisVaksrk%3D 2819495 20002448
    • Chen B, Hu J, Liao L (2010) Flk-1 + mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6. Clin Exp Immunol 159:292-302
    • (2010) Clin Exp Immunol , vol.159 , pp. 292-302
    • Chen, B.1    Hu, J.2    Liao, L.3
  • 53
    • 34247231682 scopus 로고    scopus 로고
    • Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis
    • 1:CAS:528:DC%2BD2sXltFKgs74%3D 17393437
    • Augello A, Tasso R, Negrini SM, Cancedda R, Pennesi G (2007) Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum 56:1175-1186
    • (2007) Arthritis Rheum , vol.56 , pp. 1175-1186
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3    Cancedda, R.4    Pennesi, G.5
  • 54
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • 1:CAS:528:DC%2BD1MXltFenu7Y%3D 19333946
    • GonZalez MA, Gonzalez-Rey E, Rico L, Buscher D, Delgado M (2009) Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum 60:1006-1019
    • (2009) Arthritis Rheum , vol.60 , pp. 1006-1019
    • Gonzalez, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Buscher, D.4    Delgado, M.5
  • 55
    • 73449133395 scopus 로고    scopus 로고
    • Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis
    • 1:CAS:528:DC%2BC3cXhtFOlsLs%3D 19124525
    • Gonzalez-Rey E, Gonzalez MA, Varela N, O'Valle F, Hernandez-Cortes P, Rico L, Buscher D, Delgado M (2010) Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis. Ann Rheum Dis 69:241-248
    • (2010) Ann Rheum Dis , vol.69 , pp. 241-248
    • Gonzalez-Rey, E.1    Gonzalez, M.A.2    Varela, N.3    O'Valle, F.4    Hernandez-Cortes, P.5    Rico, L.6    Buscher, D.7    Delgado, M.8
  • 58
    • 47249155734 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice
    • 1:CAS:528:DC%2BD1cXhtVOnu7zM 2492894 18713142
    • Choi JJ, Yoo SA, Park SJ, Kang YJ, Kim WU, Oh IH, Cho CS (2008) Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice. Clin Exp Immunol 153:269-276
    • (2008) Clin Exp Immunol , vol.153 , pp. 269-276
    • Choi, J.J.1    Yoo, S.A.2    Park, S.J.3    Kang, Y.J.4    Kim, W.U.5    Oh, I.H.6    Cho, C.S.7
  • 59
    • 79958060173 scopus 로고    scopus 로고
    • Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis
    • 1:CAS:528:DC%2BC3MXmslOkurw%3D 21384335
    • Park MJ, Park HS, Cho ML, Oh HJ, Cho YG, Min SY, Chung BH, Lee JW, Kim HY, Cho SG (2011) Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis. Arthritis Rheum 63:1668-1680
    • (2011) Arthritis Rheum , vol.63 , pp. 1668-1680
    • Park, M.J.1    Park, H.S.2    Cho, M.L.3    Oh, H.J.4    Cho, Y.G.5    Min, S.Y.6    Chung, B.H.7    Lee, J.W.8    Kim, H.Y.9    Cho, S.G.10
  • 60
    • 80054716864 scopus 로고    scopus 로고
    • Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells
    • 3222617 22017805
    • Ra JC, Kang SK, Shin IS, Park HG, Joo SA, Kim JG, Kang BC, Lee YS, Nakama K, Piao M, Sohl B, Kurtz A (2011) Stem cell treatment for patients with autoimmune disease by systemic infusion of culture-expanded autologous adipose tissue derived mesenchymal stem cells. J Transl Med 9:181
    • (2011) J Transl Med , vol.9 , pp. 181
    • Ra, J.C.1    Kang, S.K.2    Shin, I.S.3    Park, H.G.4    Joo, S.A.5    Kim, J.G.6    Kang, B.C.7    Lee, Y.S.8    Nakama, K.9    Piao, M.10    Sohl, B.11    Kurtz, A.12
  • 62
    • 80052729448 scopus 로고    scopus 로고
    • Antiosteoporotic activity of dioscorea alata L.cv. Phyto through driving mesenchymal stem cells differentiation for bone formation
    • 3132482 21760825
    • Peng KY, Horing LY, Sung HC, Huang HC, Wu RT (2011) Antiosteoporotic activity of dioscorea alata L.cv. Phyto through driving mesenchymal stem cells differentiation for bone formation. Evid Based Complement Alternat Med 2011:712892
    • (2011) Evid Based Complement Alternat Med , vol.2011 , pp. 712892
    • Peng, K.Y.1    Horing, L.Y.2    Sung, H.C.3    Huang, H.C.4    Wu, R.T.5
  • 63
    • 31044432767 scopus 로고    scopus 로고
    • Pathogenies of osteoporosis: Concepts, conflicts, and prospects
    • 1:CAS:528:DC%2BD2MXhtlSqtLzJ 1297264 16322775
    • Raisz LA (2005) Pathogenies of osteoporosis: concepts, conflicts, and prospects. J Clin Invest 115:3318-3325
    • (2005) J Clin Invest , vol.115 , pp. 3318-3325
    • Raisz, L.A.1
  • 64
    • 33746736852 scopus 로고    scopus 로고
    • Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model
    • 1:CAS:528:DC%2BD28XnslOis70%3D 16889506
    • Wang Z, Goh J, De Das S, Ge Z, Ouyang H, Chong JS, Low SL, Lee EH (2006) Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model. Tissue Eng 12:1753-1761
    • (2006) Tissue Eng , vol.12 , pp. 1753-1761
    • Wang, Z.1    Goh, J.2    De Das, S.3    Ge, Z.4    Ouyang, H.5    Chong, J.S.6    Low, S.L.7    Lee, E.H.8
  • 65
    • 0036705312 scopus 로고    scopus 로고
    • Cell-mediated gene therapy for bone formation and regeneration
    • 1:CAS:528:DC%2BD3sXhsVCqu7w%3D 12222877
    • Turgeman G, Aslan H, Gazit Z, Gazit D (2002) Cell-mediated gene therapy for bone formation and regeneration. Curr Opin Mol Ther 4:390-394
    • (2002) Curr Opin Mol Ther , vol.4 , pp. 390-394
    • Turgeman, G.1    Aslan, H.2    Gazit, Z.3    Gazit, D.4
  • 66
    • 0027973996 scopus 로고
    • Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy
    • 1:CAS:528:DyaK2MXitFyhu70%3D 7876320
    • Bruder SP, Fink DJ, Caplan AI (1994) Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy. J Cell Biochem 56:283-294
    • (1994) J Cell Biochem , vol.56 , pp. 283-294
    • Bruder, S.P.1    Fink, D.J.2    Caplan, A.I.3
  • 67
    • 0031953736 scopus 로고    scopus 로고
    • Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: Implications for osteopenic disorders
    • 1:STN:280:DyaK1c7osVanuw%3D%3D 9525337
    • Nuttall ME, Patton AJ, Olivera DJ, Nadeau DP, Gowen M (1998) Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders. J Bone Miner Res 13:371-382
    • (1998) J Bone Miner Res , vol.13 , pp. 371-382
    • Nuttall, M.E.1    Patton, A.J.2    Olivera, D.J.3    Nadeau, D.P.4    Gowen, M.5
  • 69
    • 38349181025 scopus 로고    scopus 로고
    • Estrogen modulates estrogen receptor alpha and beta expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice
    • 11455579
    • Zhou S, Zilberman Y, Wassermann K, Bain SD, Sadovsky Y, Gazit D (2001) Estrogen modulates estrogen receptor alpha and beta expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice. J Cell Biochem Suppl 36(Suppl):144-155
    • (2001) J Cell Biochem Suppl , vol.36 , Issue.SUPPL. , pp. 144-155
    • Zhou, S.1    Zilberman, Y.2    Wassermann, K.3    Bain, S.D.4    Sadovsky, Y.5    Gazit, D.6
  • 70
    • 78049427750 scopus 로고    scopus 로고
    • Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats
    • 20373890
    • Ocarino Nde M, Boeloni JN, Jorgetti V, Gomes DA, Goes AM, Serakides R (2010) Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats. Connect Tissue Res 51:426-433
    • (2010) Connect Tissue Res , vol.51 , pp. 426-433
    • Ocarino Nde, M.1    Boeloni, J.N.2    Jorgetti, V.3    Gomes, D.A.4    Goes, A.M.5    Serakides, R.6
  • 72
    • 84155164502 scopus 로고    scopus 로고
    • Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys
    • 1:CAS:528:DC%2BC3MXhsVymtb3I 21308366
    • Jerome C, Missbach M, Gamse R (2011) Balicatib, a cathepsin K inhibitor, stimulates periosteal bone formation in monkeys. Osteoporos Int 22:3001-3011
    • (2011) Osteoporos Int , vol.22 , pp. 3001-3011
    • Jerome, C.1    Missbach, M.2    Gamse, R.3
  • 73
    • 70350462296 scopus 로고    scopus 로고
    • A study on repairing mandibular defect by means of tissue-engineering and human bone morphogenetic protein-2 gene transfection in osteoporotic rats
    • 17067463
    • Tang YC, Tang W, Tian WD, Chen XZ, Li SW (2006) A study on repairing mandibular defect by means of tissue-engineering and human bone morphogenetic protein-2 gene transfection in osteoporotic rats. Zhonghua Kou Qiang Yi Xue Za Zhi 41:430-431
    • (2006) Zhonghua Kou Qiang Yi Xue Za Zhi , vol.41 , pp. 430-431
    • Tang, Y.C.1    Tang, W.2    Tian, W.D.3    Chen, X.Z.4    Li, S.W.5
  • 75
    • 0034988303 scopus 로고    scopus 로고
    • Bone marrow stromal stem cells: Nature, biology, and potential applications
    • 1:STN:280:DC%2BD3MzlvVamsw%3D%3D 11359943
    • Bianco P, Riminucci M, Gronthos S, Robey PG (2001) Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells 19:180-192
    • (2001) Stem Cells , vol.19 , pp. 180-192
    • Bianco, P.1    Riminucci, M.2    Gronthos, S.3    Robey, P.G.4
  • 76
    • 77956022298 scopus 로고    scopus 로고
    • Is there a role for bone morphogenetic proteins in osteoporotic fractures?
    • 20082786
    • Kanakaris NK, Petsatodis G, Tagil M, Giannoudis PV (2009) Is there a role for bone morphogenetic proteins in osteoporotic fractures? Injury 40(Suppl 3):S21-S26
    • (2009) Injury , vol.40 , Issue.SUPPL. 3
    • Kanakaris, N.K.1    Petsatodis, G.2    Tagil, M.3    Giannoudis, P.V.4
  • 78
    • 33646946177 scopus 로고    scopus 로고
    • Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep
    • 1:CAS:528:DC%2BD28XkslKis7s%3D 16716108
    • Egermann M, Baltzer AW, Adamaszek S, Evans C, Robbins P, Schneider E, Lill CA (2006) Direct adenoviral transfer of bone morphogenetic protein-2 cDNA enhances fracture healing in osteoporotic sheep. Hum Gene Ther 17:507-517
    • (2006) Hum Gene Ther , vol.17 , pp. 507-517
    • Egermann, M.1    Baltzer, A.W.2    Adamaszek, S.3    Evans, C.4    Robbins, P.5    Schneider, E.6    Lill, C.A.7
  • 79
    • 11144221286 scopus 로고    scopus 로고
    • Osteogenic differentiation of recombinant adeno-associated virus 2-transduced murine mesenchymal stem cells and development of an immunocompetent mouse model for ex vivo osteoporosis gene therapy
    • 1:CAS:528:DC%2BD2MXktVWgsw%3D%3D 15684696
    • Kumar S, Mahendra G, Nagy TR, Ponnazhagan S (2004) Osteogenic differentiation of recombinant adeno-associated virus 2-transduced murine mesenchymal stem cells and development of an immunocompetent mouse model for ex vivo osteoporosis gene therapy. Hum Gene Ther 15:1197-1206
    • (2004) Hum Gene Ther , vol.15 , pp. 1197-1206
    • Kumar, S.1    Mahendra, G.2    Nagy, T.R.3    Ponnazhagan, S.4
  • 81
    • 33847268721 scopus 로고    scopus 로고
    • Callus formation enhanced by BMP-7 ex vivo gene therapy during distraction osteogenesis in rats
    • 1:CAS:528:DC%2BD2sXjtFCmurY%3D 17089407
    • Hu J, Qi MC, Zou SJ, Li JH, Luo E (2007) Callus formation enhanced by BMP-7 ex vivo gene therapy during distraction osteogenesis in rats. J Orthop Res 25:241-251
    • (2007) J Orthop Res , vol.25 , pp. 241-251
    • Hu, J.1    Qi, M.C.2    Zou, S.J.3    Li, J.H.4    Luo, E.5
  • 82
    • 0036871171 scopus 로고    scopus 로고
    • Ex vivo bone morphogenetic protein-9 gene therapy using human mesenchymal stem cells induces spinal fusion in rodents
    • Dumon RJ, Dyoub H, Li JZ, Dumont AS, Kallmes DF, Hankins GR, Helm GA (2002) Ex vivo bone morphogenetic protein-9 gene therapy using human mesenchymal stem cells induces spinal fusion in rodents. Neurosurgery 51:1239-1245
    • (2002) Neurosurgery , vol.51 , pp. 1239-1245
    • Dumon, R.J.1    Dyoub, H.2    Li, J.Z.3    Dumont, A.S.4    Kallmes, D.F.5    Hankins, G.R.6    Helm, G.A.7
  • 83
    • 33749076721 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer of receptor activator of nuclear factor-kappaB-Fc prevents bone loss in ovariectomized mice
    • 1:CAS:528:DC%2BD28XhtFKlsbjL 16556708
    • Kim D, Cho SW, Her SJ, Yang JY, Kim SW, Kim SY, Shin CS (2006) Retrovirus-mediated gene transfer of receptor activator of nuclear factor-kappaB-Fc prevents bone loss in ovariectomized mice. Stem Cells 24:1798-1805
    • (2006) Stem Cells , vol.24 , pp. 1798-1805
    • Kim, D.1    Cho, S.W.2    Her, S.J.3    Yang, J.Y.4    Kim, S.W.5    Kim, S.Y.6    Shin, C.S.7
  • 84
    • 70449123822 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice
    • 1:CAS:528:DC%2BD1MXosFWiu7Y%3D 19603006
    • Cho SW, Sun HJ, Yang JY, Jung JY, An JH, Cho HY, Choi HJ, Kim SW, Kim SY, Kim D, Shin CS (2009) Transplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice. Mol Ther 17:1979-1987
    • (2009) Mol Ther , vol.17 , pp. 1979-1987
    • Cho, S.W.1    Sun, H.J.2    Yang, J.Y.3    Jung, J.Y.4    An, J.H.5    Cho, H.Y.6    Choi, H.J.7    Kim, S.W.8    Kim, S.Y.9    Kim, D.10    Shin, C.S.11
  • 85
    • 65949116788 scopus 로고    scopus 로고
    • Restoration of bone mass and strength in glucocorticoid-treated mice by systemic transplantation of CXCR4 and cbfa-1 co-expressing mesenchymal stem cells
    • 1:CAS:528:DC%2BD1MXlvVWhtbo%3D 19113920
    • Lien CY, Chih-Yuan Ho K, Lee OK, Blunn GW, Su Y (2009) Restoration of bone mass and strength in glucocorticoid-treated mice by systemic transplantation of CXCR4 and cbfa-1 co-expressing mesenchymal stem cells. J Bone Miner Res 24:837-848
    • (2009) J Bone Miner Res , vol.24 , pp. 837-848
    • Lien, C.Y.1    Chih-Yuan Ho, K.2    Lee, O.K.3    Blunn, G.W.4    Su, Y.5
  • 86
    • 84863136375 scopus 로고    scopus 로고
    • Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures
    • 1:CAS:528:DC%2BC38XltV2rsrg%3D 21545685
    • Chen HT, Lee MJ, Chen CH et al (2012) Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures. J Cell Mol Med 16:582-593
    • (2012) J Cell Mol Med , vol.16 , pp. 582-593
    • Chen, H.T.1    Lee, M.J.2    Chen, C.H.3
  • 87
    • 27544495595 scopus 로고    scopus 로고
    • Treatment for osteonecrosis of the femoral head: Comparison of extracorporeal shock waves with core decompression and bone-grafting
    • 16264111
    • Wang CJ, Wang FS, Huang CC, Yang KD, Weng LH, Huang HY (2005) Treatment for osteonecrosis of the femoral head: comparison of extracorporeal shock waves with core decompression and bone-grafting. J Bone Joint Surg Am 87:2380-2387
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 2380-2387
    • Wang, C.J.1    Wang, F.S.2    Huang, C.C.3    Yang, K.D.4    Weng, L.H.5    Huang, H.Y.6
  • 88
    • 77957682853 scopus 로고    scopus 로고
    • Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: Preliminary results
    • 20877951
    • Feitosa ML, Fadel L, Beltrao-Braga PC et al (2010) Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: preliminary results. Acta Cir Bras 25:416-422
    • (2010) Acta Cir Bras , vol.25 , pp. 416-422
    • Feitosa, M.L.1    Fadel, L.2    Beltrao-Braga, P.C.3
  • 89
    • 0025968937 scopus 로고
    • MRI appearance of femoral head osteonecrosis following core decompression and bone grafting
    • 1:STN:280:DyaK3M3ht12rtg%3D%3D 2020856
    • Chan TW, Dalinka MK, Steinberg ME, Kressel HY (1991) MRI appearance of femoral head osteonecrosis following core decompression and bone grafting. Skeletal Radiol 20:103-107
    • (1991) Skeletal Radiol , vol.20 , pp. 103-107
    • Chan, T.W.1    Dalinka, M.K.2    Steinberg, M.E.3    Kressel, H.Y.4
  • 90
    • 0030133560 scopus 로고    scopus 로고
    • Avascular osteonecrosis of the femoral head treated with a vascularized iliac bone graft: Preliminary results and follow-up with radiography and MR imaging
    • 1:STN:280:DyaK2s%2Flt12qtQ%3D%3D 8897626
    • Wassenaar RP, Verburg H, Taconis WK, van der Eijken JW (1996) Avascular osteonecrosis of the femoral head treated with a vascularized iliac bone graft: preliminary results and follow-up with radiography and MR imaging. Radiographics 16:585-594
    • (1996) Radiographics , vol.16 , pp. 585-594
    • Wassenaar, R.P.1    Verburg, H.2    Taconis, W.K.3    Van Der Eijken, J.W.4
  • 91
    • 0036908768 scopus 로고    scopus 로고
    • Treatment of osteonecrosis with autologous bone marrow grafting
    • 12461352
    • Hernigou P, Beaujean F (2002) Treatment of osteonecrosis with autologous bone marrow grafting. Clin Orthop 405:14-23
    • (2002) Clin Orthop , vol.405 , pp. 14-23
    • Hernigou, P.1    Beaujean, F.2
  • 93
    • 2642542690 scopus 로고    scopus 로고
    • Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study
    • 15173287
    • Gangji V, Hauzeur JP, Matos C, De Maertelaer V, Toungouz M, Lambermont M (2004) Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study. J Bone Joint Surg Am 86-A:1153-1160
    • (2004) J Bone Joint Surg Am , vol.86 , pp. 1153-1160
    • Gangji, V.1    Hauzeur, J.P.2    Matos, C.3    De Maertelaer, V.4    Toungouz, M.5    Lambermont, M.6
  • 94
    • 77955466134 scopus 로고    scopus 로고
    • Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells
    • 19621230
    • Wang BL, Sun W, Shi ZC et al (2010) Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells. Arch Orthop Trauma Surg 130:859-865
    • (2010) Arch Orthop Trauma Surg , vol.130 , pp. 859-865
    • Wang, B.L.1    Sun, W.2    Shi, Z.C.3
  • 95
    • 60049101503 scopus 로고    scopus 로고
    • Cell therapy of hip osteonecrosis with autologous bone marrow grafting
    • 2739495 19753178
    • Hernigou P, Poignard A, Zilber S, Rouard H (2009) Cell therapy of hip osteonecrosis with autologous bone marrow grafting. Indian J Orthop 43:40-45
    • (2009) Indian J Orthop , vol.43 , pp. 40-45
    • Hernigou, P.1    Poignard, A.2    Zilber, S.3    Rouard, H.4
  • 96
    • 80054838532 scopus 로고    scopus 로고
    • Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: Five year follow-up of a prospective controlled study
    • 21821156
    • GangJi V, De Maertelaer V, Hauzeur JP (2011) Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: five year follow-up of a prospective controlled study. Bone 49:1005-1009
    • (2011) Bone , vol.49 , pp. 1005-1009
    • Gangji, V.1    De Maertelaer, V.2    Hauzeur, J.P.3
  • 97
    • 0031917182 scopus 로고    scopus 로고
    • Growth factors released from bone marrow are promising tools in orthopedic surgery
    • 1:STN:280:DyaK1c3gtV2gtQ%3D%3D 9540115
    • Hernigou P (1998) Growth factors released from bone marrow are promising tools in orthopedic surgery. Rev Rhum Engl Ed 65:79-84
    • (1998) Rev Rhum Engl Ed , vol.65 , pp. 79-84
    • Hernigou, P.1
  • 98
    • 0036667101 scopus 로고    scopus 로고
    • Regenerative medicine through mesenchymal stem cells for bone and cartilage repair
    • 12186258
    • Noel D, Djouad F, Jorgense C (2002) Regenerative medicine through mesenchymal stem cells for bone and cartilage repair. Curr Opin Investig Drugs 3:1000-1004
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 1000-1004
    • Noel, D.1    Djouad, F.2    Jorgense, C.3
  • 99
    • 74049118902 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy for nonmusculoskeletal diseases: Emerging applications
    • 19523328
    • Kuo TK, Ho JH, Lee OK (2009) Mesenchymal stem cell therapy for nonmusculoskeletal diseases: emerging applications. Cell Transplant 18:1013-1028
    • (2009) Cell Transplant , vol.18 , pp. 1013-1028
    • Kuo, T.K.1    Ho, J.H.2    Lee, O.K.3
  • 100
    • 33750685030 scopus 로고    scopus 로고
    • Use of genetically engineered bone-marrow stem cells to treat femoral defects: An experimental study
    • 17079384
    • Cui Q, Xiao Z, Li X, Saleh KJ, Balian G (2006) Use of genetically engineered bone-marrow stem cells to treat femoral defects: an experimental study. J Bone Joint Surg Am 88(Suppl 3):167-172
    • (2006) J Bone Joint Surg Am , vol.88 , Issue.SUPPL. 3 , pp. 167-172
    • Cui, Q.1    Xiao, Z.2    Li, X.3    Saleh, K.J.4    Balian, G.5
  • 101
    • 41849090064 scopus 로고    scopus 로고
    • Regenerative effects of transplanting autologous mesenchymal stem cells on corticosteroid-induced osteonecrosis in rabbits
    • Matsuya H, Kushida T, Asada T, Umeda M, Wada T, Iida H (2008) Regenerative effects of transplanting autologous mesenchymal stem cells on corticosteroid-induced osteonecrosis in rabbits. Mod Rhheumatol 18:132-139
    • (2008) Mod Rhheumatol , vol.18 , pp. 132-139
    • Matsuya, H.1    Kushida, T.2    Asada, T.3    Umeda, M.4    Wada, T.5    Iida, H.6
  • 102
    • 79751509462 scopus 로고    scopus 로고
    • Intravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head
    • 3020395 21234272
    • Li ZH, Liao W, Cui XL et al (2011) Intravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head. Int J Med Sci 8:74-83
    • (2011) Int J Med Sci , vol.8 , pp. 74-83
    • Li, Z.H.1    Liao, W.2    Cui, X.L.3
  • 103
    • 63349107849 scopus 로고    scopus 로고
    • Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head
    • 18925660
    • Yan Z, Hang D, Guo C, Chen Z (2009) Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head. J Orthop Res 27:442-446
    • (2009) J Orthop Res , vol.27 , pp. 442-446
    • Yan, Z.1    Hang, D.2    Guo, C.3    Chen, Z.4
  • 104
    • 78651080413 scopus 로고    scopus 로고
    • Micro-CT-based bone ceramic scaffolding and its performance after seeding with mesenchymal stem cells for repair of load-bearing bone defect in canine femoral head
    • 21210512
    • Peng J, Wen C, Wang A et al (2011) Micro-CT-based bone ceramic scaffolding and its performance after seeding with mesenchymal stem cells for repair of load-bearing bone defect in canine femoral head. J Biomed Mater Res B Appl Biomater 96:316-325
    • (2011) J Biomed Mater Res B Appl Biomater , vol.96 , pp. 316-325
    • Peng, J.1    Wen, C.2    Wang, A.3
  • 105
    • 77957682853 scopus 로고    scopus 로고
    • Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: Preliminary results
    • 20877951
    • Feitosa ML, Fadel L, Beltrao-Braga PC et al (2010) Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: preliminary results. Acta Cir Bras 25:416-422
    • (2010) Acta Cir Bras , vol.25 , pp. 416-422
    • Feitosa, M.L.1    Fadel, L.2    Beltrao-Braga, P.C.3
  • 106
    • 64549157663 scopus 로고    scopus 로고
    • An experimental study on treatment of steroid-associated femoral head necrosis with simvastatin and BMSCs transplantation
    • 1:CAS:528:DC%2BD1cXmtlyjur8%3D 18396704
    • Yang J, Wang L, Xu Y, Wang J, Wang Y (2008) An experimental study on treatment of steroid-associated femoral head necrosis with simvastatin and BMSCs transplantation. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22:290-294
    • (2008) Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi , vol.22 , pp. 290-294
    • Yang, J.1    Wang, L.2    Xu, Y.3    Wang, J.4    Wang, Y.5
  • 107
    • 84861566211 scopus 로고    scopus 로고
    • Change in hepatocyte growth factor concentration promote mesenchymal stem cell-mediated osteogenic regeneration
    • 1:CAS:528:DC%2BC38Xht1SjsbzF 21831134
    • Wen Q, Zhou L, Zhou C, Zhou M, Luo W, Ma L (2012) Change in hepatocyte growth factor concentration promote mesenchymal stem cell-mediated osteogenic regeneration. J Cell Mol Med 16:1260-1273
    • (2012) J Cell Mol Med , vol.16 , pp. 1260-1273
    • Wen, Q.1    Zhou, L.2    Zhou, C.3    Zhou, M.4    Luo, W.5    Ma, L.6
  • 108
    • 84871456160 scopus 로고    scopus 로고
    • Treatment for osteonecrosis of femoral head by hVEGF-165 gene modified marrow stromal stem cells under arthroscope
    • 1:CAS:528:DC%2BC3cXhvVGitbs%3D 20137681
    • Liu BY, Zhao DW (2009) Treatment for osteonecrosis of femoral head by hVEGF-165 gene modified marrow stromal stem cells under arthroscope. Zhonghua Yi Xue Za Zhi 89:2629-2633
    • (2009) Zhonghua Yi Xue Za Zhi , vol.89 , pp. 2629-2633
    • Liu, B.Y.1    Zhao, D.W.2
  • 109
    • 77954487489 scopus 로고    scopus 로고
    • Angiopoiesis and bone regeneration via co-expression of the hVEGF and hBMP genes from an adeno-associated viral vector in vitro and in vivo
    • 1:CAS:528:DC%2BC3cXotlSnuro%3D 20581855
    • Zhang C, Wang KZ, Qiang H et al (2010) Angiopoiesis and bone regeneration via co-expression of the hVEGF and hBMP genes from an adeno-associated viral vector in vitro and in vivo. Acta Pharmacol Sin 31:821-830
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 821-830
    • Zhang, C.1    Wang, K.Z.2    Qiang, H.3
  • 110
    • 77957000866 scopus 로고    scopus 로고
    • Effects of recombinant adeno-associated viral vectors on angiopoiesis and osteogenesis in cultured rabbit bone marrow stem cells via co-expressing hVEGF and hBMP genes: A preliminary study in vitro
    • 1:CAS:528:DC%2BC3cXht1Whsb7O 20817238
    • Shi ZB, Wang KZ (2010) Effects of recombinant adeno-associated viral vectors on angiopoiesis and osteogenesis in cultured rabbit bone marrow stem cells via co-expressing hVEGF and hBMP genes: a preliminary study in vitro. Tissue Cell 42:314-321
    • (2010) Tissue Cell , vol.42 , pp. 314-321
    • Shi, Z.B.1    Wang, K.Z.2
  • 111
    • 79960827064 scopus 로고    scopus 로고
    • Study on effect of recombinant adeno-associated virus co-expressing human vascular endothelial growth factor 165 and human bone morphogenetic protein 7 genes on bone regeneration and angiopoiesis in vivo
    • 1:CAS:528:DC%2BC3MXmvVGiu7o%3D 21261092
    • Zhang C, Ma Q, Qiang H, Li M, Dang X, Wang K (2010) Study on effect of recombinant adeno-associated virus co-expressing human vascular endothelial growth factor 165 and human bone morphogenetic protein 7 genes on bone regeneration and angiopoiesis in vivo. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24:1449-1454
    • (2010) Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi , vol.24 , pp. 1449-1454
    • Zhang, C.1    Ma, Q.2    Qiang, H.3    Li, M.4    Dang, X.5    Wang, K.6
  • 112
    • 33846881606 scopus 로고    scopus 로고
    • Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats
    • 1:STN:280:DC%2BD2svlvFKrtA%3D%3D 17259431
    • Tang TT, Lu B, Yue B et al (2007) Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats. J Bone Joint Surg Br 89:127-129
    • (2007) J Bone Joint Surg Br , vol.89 , pp. 127-129
    • Tang, T.T.1    Lu, B.2    Yue, B.3
  • 113
    • 45849142558 scopus 로고    scopus 로고
    • Treatment of osteonecrosis of femoral head with BMSCs-seeded bio-derived bone materials combined with rhBMP-2 in rabbits
    • 1:CAS:528:DC%2BD1cXosFWiur0%3D 18507947
    • Xiao ZM, Jiang H, Zhan XL, Wu ZG, Zhang XL (2008) Treatment of osteonecrosis of femoral head with BMSCs-seeded bio-derived bone materials combined with rhBMP-2 in rabbits. Chin J Traumatol 11:165-170
    • (2008) Chin J Traumatol , vol.11 , pp. 165-170
    • Xiao, Z.M.1    Jiang, H.2    Zhan, X.L.3    Wu, Z.G.4    Zhang, X.L.5
  • 114
    • 79952118034 scopus 로고    scopus 로고
    • Treatment of early avascular necrosis of femoral head by core decompression combined with autologous bone marrow mesenchymal stem cells transplantation
    • 20632513
    • Chang T, Tang K, Tao X et al (2010) Treatment of early avascular necrosis of femoral head by core decompression combined with autologous bone marrow mesenchymal stem cells transplantation. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24:739-743
    • (2010) Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi , vol.24 , pp. 739-743
    • Chang, T.1    Tang, K.2    Tao, X.3
  • 115
    • 82655170631 scopus 로고    scopus 로고
    • Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells
    • 22094904
    • Zhao D, Cui D, Wang B et al (2012) Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells. Bone 50:325-330
    • (2012) Bone , vol.50 , pp. 325-330
    • Zhao, D.1    Cui, D.2    Wang, B.3
  • 116
    • 84856466024 scopus 로고    scopus 로고
    • Autologous adipose tissue-derived stem cells induce persistent bone-like tissue in osteonecrotic femoral heads
    • 22270740
    • Pak J (2012) Autologous adipose tissue-derived stem cells induce persistent bone-like tissue in osteonecrotic femoral heads. Pain Physician 15:75-85
    • (2012) Pain Physician , vol.15 , pp. 75-85
    • Pak, J.1
  • 117
    • 0025777221 scopus 로고
    • Osteogenesis imperfecta: Translation of mutation to phenotype
    • 1:STN:280:DyaK3MznsVCktA%3D%3D 1895312
    • Byers PH, Wallis GA, Willing MC (1991) Osteogenesis imperfecta: translation of mutation to phenotype. J Med Genet 28:433-442
    • (1991) J Med Genet , vol.28 , pp. 433-442
    • Byers, P.H.1    Wallis, G.A.2    Willing, M.C.3
  • 118
    • 1842487509 scopus 로고    scopus 로고
    • High proportion of mutant osteoblasts is compatible with normal skeletal function in mosaic carriers of osteogenesis imperfecta
    • 1:CAS:528:DC%2BD2cXivFCntL8%3D 1181952 15024692
    • Cabral WA, Marini JC (2004) High proportion of mutant osteoblasts is compatible with normal skeletal function in mosaic carriers of osteogenesis imperfecta. Am J Hum Genet 74:752-760
    • (2004) Am J Hum Genet , vol.74 , pp. 752-760
    • Cabral, W.A.1    Marini, J.C.2
  • 119
    • 0037106533 scopus 로고    scopus 로고
    • Validation in mesenchymal progenitor cells of a mutation-independent ex vivo approach to gene therapy for osteogenesis imperfecta
    • 1:CAS:528:DC%2BD38XmvVamur8%3D
    • Millington-Ward S, Allers C, Tuohy G et al (2002) Validation in mesenchymal progenitor cells of a mutation-independent ex vivo approach to gene therapy for osteogenesis imperfecta. Hum Mol Gent 11:2201-2206
    • (2002) Hum Mol Gent , vol.11 , pp. 2201-2206
    • Millington-Ward, S.1    Allers, C.2    Tuohy, G.3
  • 120
    • 0002624625 scopus 로고
    • Osteogenesis imperfecta, rehabilitation medicine, fundamental research and mesenchymal stem cells
    • 1:STN:280:DC%2BD2cnjs1Ggsg%3D%3D 15612374
    • Caplan AI (1995) Osteogenesis imperfecta, rehabilitation medicine, fundamental research and mesenchymal stem cells. Connect Tissue Res 31:S9-S14
    • (1995) Connect Tissue Res , vol.31
    • Caplan, A.I.1
  • 121
    • 0032477883 scopus 로고    scopus 로고
    • Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
    • 1:CAS:528:DyaK1cXosFSrsA%3D%3D
    • Pereira RF, O'Hara MD, Laptev AV et al (1998) Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Pro Natl Acad Sci USA 95:1142-1147
    • (1998) Pro Natl Acad Sci USA , vol.95 , pp. 1142-1147
    • Pereira, R.F.1    O'Hara, M.D.2    Laptev, A.V.3
  • 122
    • 38949106568 scopus 로고    scopus 로고
    • Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice
    • 1:CAS:528:DC%2BD1cXhvFeis7w%3D 17967940
    • Guillot PV, Abass O, Bassett JH et al (2008) Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice. Blood 111:1717-1725
    • (2008) Blood , vol.111 , pp. 1717-1725
    • Guillot, P.V.1    Abass, O.2    Bassett, J.H.3
  • 123
    • 0032976690 scopus 로고    scopus 로고
    • Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
    • 1:CAS:528:DyaK1MXhsVSltLk%3D 10086387
    • Horwitz EM, Prockop DJ, Fitzpatrick LA et al (1999) Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 5:309-313
    • (1999) Nat Med , vol.5 , pp. 309-313
    • Horwitz, E.M.1    Prockop, D.J.2    Fitzpatrick, L.A.3
  • 124
    • 0035283077 scopus 로고    scopus 로고
    • Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta
    • 1:CAS:528:DC%2BD3MXhs12ltrs%3D 11222364
    • Horwitz EM, Prockop DJ, Gordon PL et al (2001) Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood 97:1227-1231
    • (2001) Blood , vol.97 , pp. 1227-1231
    • Horwitz, E.M.1    Prockop, D.J.2    Gordon, P.L.3
  • 125
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • 1:CAS:528:DC%2BD38XltF2htb8%3D 12084934
    • Horwitz EM, Gordon PL, Koo WK et al (2002) Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc Natl Acad Sci USA 99:8932-8937
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8932-8937
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3
  • 126
    • 20544455396 scopus 로고    scopus 로고
    • Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patients with severe osteogenesis imperfecta
    • 15940052
    • Le Blanc K, Gotherstrom C, Ringden O et al (2005) Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patients with severe osteogenesis imperfecta. Transplantation 79:1607-1614
    • (2005) Transplantation , vol.79 , pp. 1607-1614
    • Le Blanc, K.1    Gotherstrom, C.2    Ringden, O.3
  • 127
    • 6444227272 scopus 로고    scopus 로고
    • RNAi of COL1A1 in mesenchymal progenitor cells
    • 1:CAS:528:DC%2BD2cXns1ektro%3D 15241481
    • Millington-Ward S, McMahon HP, Allen D et al (2004) RNAi of COL1A1 in mesenchymal progenitor cells. Eur J Hum Genet 12:864-866
    • (2004) Eur J Hum Genet , vol.12 , pp. 864-866
    • Millington-Ward, S.1    McMahon, H.P.2    Allen, D.3
  • 128
    • 84926117997 scopus 로고    scopus 로고
    • Allele-specific gene silencing in osteogenesis imperfecta
    • 1:CAS:528:DC%2BC3MXhsFWjs77F 21865757
    • Ljunggren O, Lindahl K, Rubin CJ, Kindmark A (2011) Allele-specific gene silencing in osteogenesis imperfecta. Endocr Dev 21:85-90
    • (2011) Endocr Dev , vol.21 , pp. 85-90
    • Ljunggren, O.1    Lindahl, K.2    Rubin, C.J.3    Kindmark, A.4
  • 129
    • 84866503535 scopus 로고    scopus 로고
    • Human mesenchymal stromal cells senesce with exogenous OCT4
    • 1:CAS:528:DC%2BC38Xhtlygu7%2FI 22746537
    • Jaganathan BG, Bonnet D (2012) Human mesenchymal stromal cells senesce with exogenous OCT4. Cytotherapy 14:1054-1063
    • (2012) Cytotherapy , vol.14 , pp. 1054-1063
    • Jaganathan, B.G.1    Bonnet, D.2
  • 130
    • 77953945827 scopus 로고    scopus 로고
    • Aging of the inceptive cellular population: The relationship between stem cells and aging
    • 1:CAS:528:DC%2BD1MXht1GkurnJ
    • Symonds CE, Galderisi U, Giordano A (2009) Aging of the inceptive cellular population: the relationship between stem cells and aging. Aging (Albany NY) 1:372-381
    • (2009) Aging (Albany NY) , vol.1 , pp. 372-381
    • Symonds, C.E.1    Galderisi, U.2    Giordano, A.3
  • 131
    • 70349423739 scopus 로고    scopus 로고
    • In vitro senescence of rat mesenchymal stem cell is accompanied by downregulation of stemness-related and DNA damage repair genes
    • 1:CAS:528:DC%2BD1MXhtFWhtb7N 19099372
    • Galderisi U, Helmbold H, Squillaro T, Alessio N, Komm N, Khadang B, Cipollaro M, Bohn W, Giordano A (2009) In vitro senescence of rat mesenchymal stem cell is accompanied by downregulation of stemness-related and DNA damage repair genes. Stem Cells Dev 18:1033-1042
    • (2009) Stem Cells Dev , vol.18 , pp. 1033-1042
    • Galderisi, U.1    Helmbold, H.2    Squillaro, T.3    Alessio, N.4    Komm, N.5    Khadang, B.6    Cipollaro, M.7    Bohn, W.8    Giordano, A.9
  • 132
    • 84895148611 scopus 로고    scopus 로고
    • Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression
    • Aug 21 [Epub ahead of print]
    • Liu TM, Ng WM, Tan HS, Vinitha D, Yang Z, Fan JB, Zou Y, Hui JH, Lee EH, Lim B (2012) Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression. Stem Cells Dev Aug 21 [Epub ahead of print]
    • (2012) Stem Cells Dev
    • Liu, T.M.1    Ng, W.M.2    Tan, H.S.3    Vinitha, D.4    Yang, Z.5    Fan, J.B.6    Zou, Y.7    Hui, J.H.8    Lee, E.H.9    Lim, B.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.