Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis

Osteoarthritis and Cartilage

Volumn 22, Issue 2, 2014, Pages 264-274

  Stone, A V ^a   Loeser, R F ^a   Vanderman, K S ^a   Long, D L ^a   Clark, S C ^a   Ferguson, C M ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokine; Matrix metalloproteinase; Meniscus; MMP; Osteoarthritis

Indexed keywords

CHEMOKINE; COLLAGENASE 3; COMPLEMENTARY DNA; CYTOKINE; GELATINASE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; NEUTROPHIL COLLAGENASE; RNA; STROMELYSIN; STROMELYSIN 2; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CATABOLISM; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME SYNTHESIS; GENE EXPRESSION; GENE PRODUCT; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; KNEE MENISCUS; KNEE OSTEOARTHRITIS; OSTEOARTHRITIS; PATHOGENESIS; PRIMARY CELL CULTURE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TOTAL KNEE REPLACEMENT;

CYTOKINE; MATRIX METALLOPROTEINASE; MENISCUS; MMP; OSTEOARTHRITIS;

ADULT; AGED; AGED, 80 AND OVER; CELLS, CULTURED; CHEMOKINES; CULTURE MEDIA, CONDITIONED; CYTOKINES; DITERPENES; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; MATRIX METALLOPROTEINASES; MENISCI, TIBIAL; MIDDLE AGED; NF-KAPPA B; OSTEOARTHRITIS, KNEE; PROTEIN ARRAY ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84893782280     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2013.11.002     Document Type: Article

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