Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles

Journal of Orthopaedic Research

Volumn 27, Issue 4, 2009, Pages 435-441

  Segawa, Yuko ^a   Muneta, Takeshi ^a   Makino, Hatsune ^b   Nimura, Akimoto ^a   Mochizuki, Tomoyuki ^a   Ju, Young Jin ^a   Ezura, Yoichi ^a   Umezawa, Akihiro ^b   Sekiya, Ichiro ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Gene profile; Intraarticular tissue MSCs; Mesenchymal stem cells; Proline arginine rich end leucine rich repeat protein (PRELP); Synovial stem cells

Indexed keywords

ARGININE; LEUCINE; PROLINE; GLYCOPROTEIN; PRELP PROTEIN, HUMAN; SCLEROPROTEIN;

ADIPOSE TISSUE; ADOLESCENT; ADULT; AGED; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BONE MARROW; CARTILAGE CELL; CHONDROGENESIS; COLONY FORMING CELL; CONTROLLED STUDY; DONOR; FEMALE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KNEE MENISCUS; MALE; MESENCHYMAL STEM CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNOVIUM; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM;

AGED; ANTERIOR CRUCIATE LIGAMENT; CELL DIFFERENTIATION; CHONDROCYTES; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION PROFILING; GLYCOPROTEINS; HUMANS; MENISCI, TIBIAL; MESENCHYMAL STEM CELLS; SYNOVIAL MEMBRANE;

EID: 63349099190     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20786     Document Type: Article

References (21)

1. Horwitz E. M. Le Blanc K. Dominici M. et al. 2005. Clarification of the nomenclature for MSC: the international society for cellular therapy position statement. Cytotherapy 7:393-395. (Pubitemid 41671625)
2. De Bari C. Dell'ccio F. 2007. Mesenchymal stem cells in rheumatology: a regenerative approach to joint repair. Clin Sci (Lond) 113:339-348. (Pubitemid 47572274)
3. Sakaguchi Y. Sekiya I. Yagishita K. et al. 2004. Suspended cells from trabecular bone by collagenase digestion become virtually identical to mesenchymal stem cells obtained from marrow aspirates. Blood 104:2728-2735. (Pubitemid 39434954)
4. Mochizuki T. Muneta T. Sakaguchi Y. et al. 2006. Higher chondrogenic potential of fibrous synovium- and adipose synovium-derived cells compared with subcutaneous fat-derived cells-Distinguishing properties of mesenchymal stem cells in humans. Arthritis Rheum 54:843-853.
5. Nimura A. Muneta T. Koga H. et al. 2008. Increased proliferation of human synovial mesenchymal stem cells with autologous human serum: comparisons with bone marrow mesenchymal stem cells and with fet al. bovine serum. Arthritis Rheum 58:501-510.
6. Sakaguchi Y. Sekiya I. Yagishita K. et al. 2005. Comparison of human stem cells derived from various mesenchymal tissues-Superiority of synovium as a cell source. Arthritis Rheum 52:2521-2529. (Pubitemid 41117441)
7. Archer C. Dowthwaite G. Francis-West P. 2003. Development of synovial joints. Birth Defects Res C Embryo Today 69:144-155. (Pubitemid 37238406)
8. Ratajczak W. 2000. Early development of the cruciate ligaments in staged human embryos. Folia Morphol (Warsz) 59:285-290.
9. Sekiya I. Vuoristo J. Larson B. et al. 2002. In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc Natl Acad Sci USA 99:4397-4402. (Pubitemid 34285996)
10. Sekiya I. Larson B. L. Vuoristo J. T. et al. 2004. Adipogenic differentiation of human adult stem cells from bone marrow stroma (MSCs). J Bone Miner Res 19:256-264. (Pubitemid 38116739)
11. Miyagawa Y. Okita H. Nakaijima H. et al. 2008. Inducible expression of chimeric EWS/ETS proteins confers ewing's Family tumor-like phenotypes to human mesenchymal progenitor cells. Mol Cell Biol 28:2125-2137.
12. Sekiya I. Colter D. C. Prockop D. J. 2001. BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells. Biochem Biophys Res Commun 284:411-418. (Pubitemid 32917992)
13. Yoshimura H. Muneta T. Nimura A. et al. 2007. Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle. Cell Tissue Res 327:449-462. (Pubitemid 46232315)
14. Sekiya I. Larson B. L. Smith J. R. et al. 2002. Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality. Stem Cells 20:530-541. (Pubitemid 35463066)
15. Colter D. C. Sekiya I. Prockop D. J. 2001. Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci USA 98:7841-7845. (Pubitemid 32642648)
16. Dominici M. Le Blanc K. Mueller I. et al. 2006. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8:315-317. (Pubitemid 44269669)
17. Pittenger M. F. Mackay A. M. Beck S. C. et al. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147. (Pubitemid 29282067)
18. Bengtsson E. Neame P. Heinegård D. et al. 1995. The primary structure of a basic leucine-rich repeat protein, PRELP, found in connective tissues. J Biol Chem 270:25639-25644.
19. Ezura Y. Chakravarti S. Oldberg A. et al. 2000. Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons. J Cell Biol 151:779-788.
20. Ameye L. Young M. F. 2002. Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology 12:107R-116R.
21. Grover J. Chen X. Korenberg J. et al. 1996. The gene organization, chromosome location, and expression of a 55-kDa matrix protein (PRELP) of human articular cartilage. Genomics 38:109-117. (Pubitemid 26424588)