Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells

Bone

Volumn 50, Issue 1, 2012, Pages 325-330

  Zhao, Dewei ^a,b   Cui, Daping ^a,b   Wang, Benjie ^b   Tian, Fengde ^b   Guo, Lin ^b   Yang, Lei ^b   Liu, Baoyi ^b   Yu, Xiaobing ^b  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b DALIAN UNIVERSITY   (China)

Author keywords

Autologous implantation; Core decompression; Early stage; Mesenchymal stem cells; Osteonecrosis of the femoral head

Indexed keywords

CEFAZOLIN;

ADULT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE GRAFT; BONE NECROSIS; CONTROLLED STUDY; DECOMPRESSION; DISEASE COURSE; FEMALE; FEMUR HEAD NECROSIS; HARRIS HIP SCORE; HUMAN; MAJOR CLINICAL STUDY; MALE; MESENCHYMAL STEM CELL; MOVEMENT THERAPY; OUTCOME ASSESSMENT; POSTOPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL; REHABILITATION; RISK FACTOR; SURGICAL APPROACH; SURGICAL TECHNIQUE; TOTAL HIP PROSTHESIS; WEIGHT BEARING;

BONE MARROW TRANSPLANTATION; FEMUR HEAD NECROSIS; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; OSTEONECROSIS; SURVIVAL RATE; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 82655170631     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.11.002     Document Type: Article

References (26)

1. Herndon J.H., Aufranc O.E. Avascular necrosis of the femoral head in the adult. A review of its incidence in a variety of conditions. Clin Orthop Relat Res 1972, 86:43-62.
2. Glimcher M.J., Kenzora J.E. The biology of osteonecrosis of the human femoral head and its clinical implications. III. Discussion of the etiology and genesis of the pathological sequelae; comments on treatment. Clin Orthop Relat Res 1979, 140:273-312.
3. Aldridge J.M., Urbaniak J.R. Avascular necrosis of the femoral head: etiology, pathophysiology, classification, and current treatment guidelines. Am J Orthop (Belle Mead NJ) 2004, 33:327-332.
4. Babhulkar S. Osteonecrosis of femoral head: treatment by core decompression and vascular pedicle grafting. Indian J Orthop 2009, 43:27-35.
5. Jones K.B., Seshadri T., Krantz R., Keating A., Ferguson P.C. Cell-based therapies for osteonecrosis of the femoral head. Biol Blood Marrow Transplant 2008, 14:1081-1087.
6. Marker D.R., Seyler T.M., Ulrich S.D., Srivastava S., Mont M.A. Do modern techniques improve core decompression outcomes for hip osteonecrosis?. Clin Orthop Relat Res 2008, 466:1093-1103.
7. Gangji V., Hauzeur J.P. Treating osteonecrosis with autologous bone marrow cells. Skeletal Radiol 2010, 39:209-211.
8. Mont M.A., Carbone J.J., Fairbank A.C. Core decompression versus nonoperative management for osteonecrosis of the hip. Clin Orthop Relat Res 1996, 324:169-178.
9. Mont M.A., Jones L.C., Hungerford D.S. Nontraumatic osteonecrosis of the femoral head: ten years later. J Bone Joint Surg Am 2006, 88:1117-1132.
10. Nam K.W., Kim Y.L., Yoo J.J., Koo K.H., Yoon K.S., Kim H.J. Fate of untreated asymptomatic osteonecrosis of the femoral head. J Bone Joint Surg Am 2008, 90:477-484.
11. Hernigou P., Beaujean F. Treatment of osteonecrosis with autologous bone marrow grafting. Clin Orthop Relat Res 2002, 14-23.
12. Gangji V., Hauzeur J.P., Matos C., De Maertelaer V., Toungouz M., Lambermont M. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study. J Bone Joint Surg Am 2004, 86-A:1153-1160.
13. Hernigou P., Poignard A., Zilber S., Rouard H. Cell therapy of hip osteonecrosis with autologous bone marrow grafting. Indian J Orthop 2009, 43:40-45.
14. ARCO Committee on terminology and classification. ARCO News 1992, 4:41-46.
15. Harris W.H. Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. J Bone Joint Surg Am 1969, 51:737-755.
16. Hernigou P., Lambotte J.C. Volumetric analysis of osteonecrosis of the femur. Anatomical correlation using MRI. J Bone Joint Surg Br 2001, 83:672-675.
17. Steinberg M.E., Hayken G.D., Steinberg D.R. A quantitative system for staging avascular necrosis. J Bone Joint Surg Br 1995, 77:34-41.
18. Steinberg D.R., Steinberg M.E., Garino J.P., Dalinka M., Udupa J.K. Determining lesion size in osteonecrosis of the femoral head. J Bone Joint Surg Am 2006, 88(Suppl. 3):27-34.
19. Hernigou P., Beaujean F., Lambotte J.C. Decrease in the mesenchymal stem-cell pool in the proximal femur in corticosteroid-induced osteonecrosis. J Bone Joint Surg Br 1999, 81:349-355.
20. Connolly J., Guse R., Lippiello L., Dehne R. Development of an osteogenic bone-marrow preparation. J Bone Joint Surg Am 1989, 71:684-691.
21. Wang B.L., Sun W., Shi Z.C., Zhang N.F., Yue D.B., Guo W.S., Xu S.Q., Lou J.N., Li Z.R. Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells. Arch Orthop Trauma Surg 2010, 130:859-865.
22. Street J., Winter D., Wang J.H., Wakai A., McGuinness A., Redmond H.P. Is human fracture hematoma inherently angiogenic?. Clin Orthop Relat Res 2000, 378:224-237.
23. Huang Z., Ren P.G., Ma T., Smith R.L., Goodman S.B. Modulating osteogenesis of mesenchymal stem cells by modifying growth factor availability. Cytokine 2010, 513:305-310.
24. Feng Y., Yang S.H., Xiao B.J., Xu W.H., Ye S.N., Xia T., Zheng D., Liu X.Z., Liao Y.F. Decreased in the number and function of circulation endothelial progenitor cells in patients with avascular necrosis of the femoral head. Bone 2010, 46:32-40.
25. Reyes M., Dudek A., Jahagirdar B., Koodie L., Marker P.H., Verfaillie C.M. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 2002, 109:337-346.
26. Jiang Y., Jahagirdar B.N., Reinhardt R.L., Schwartz R.E., Keene C.D., Ortiz-Gonzalez X.R., Reyes M., Lenvik T., Lund T., Blackstad M., Du J., Aldrich S., Lisberg A., Low W.C., Largaespada D.A., Verfaillie C.M. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002, 418:41-49.