Nuclear receptor Nr4a2 promotes alternative polarization of macrophages and confers protection in sepsis

Journal of Biological Chemistry

Volumn 290, Issue 30, 2015, Pages 18304-18314

  Mahajan, Sahil ^a   Saini, Ankita ^a   Chandra, Vemika ^a   Nanduri, Ravikanth ^a   Kalra, Rashi ^a   Bhagyaraj, Ella ^a   Khatri, Neeraj ^a   Gupta, Pawan ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; POLARIZATION;

METABOLIC PROCESS; NUCLEAR RECEPTORS; TOLL-LIKE RECEPTORS;

MACROPHAGES;

ARGINASE 1; INTERLEUKIN 10; MAMMALIAN TARGET OF RAPAMYCIN; MERCAPTOPURINE; NUCLEAR RECEPTOR RELATED FACTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; LIGAND; LIPOPOLYSACCHARIDE; NR4A2 PROTEIN, MOUSE; PROTEIN BINDING; TOLL LIKE RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL POLARITY; CONTROLLED STUDY; DENDRITIC CELL; GENE EXPRESSION; GENE INDUCTION; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROMOTER REGION; SEPSIS; SEPTIC SHOCK; SURVIVAL RATE; TRANSCRIPTION INITIATION; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFLAMMATION; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALIA;

ANIMALS; CELL POLARITY; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 2; PHOSPHATIDYLINOSITOL 3-KINASES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; SEPSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84937851519     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.638064     Document Type: Article

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