Orphan nuclear receptor NR4A2 expressed in T cells from multiple sclerosis mediates production of inflammatory cytokines

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 24, 2008, Pages 8381-8386

  Doi, Yoshimitsu ^a   Oki, Shinji ^a   Ozawa, Tomoko ^a   Hohjoh, Hirohiko ^a   Miyake, Sachiko ^a   Yamamura, Takashi ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

EAE; IL 17; Interferon ; siRNA; Th17

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CELL NUCLEUS RECEPTOR; CYTOKINE; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 17; ORPHAN NUCLEAR RECEPTOR NR4A2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA MICROARRAY; FEMALE; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR UPREGULATION; T LYMPHOCYTE; TH1 CELL; TH17 CELL;

ANIMALS; BRAIN; CYTOKINES; DNA-BINDING PROTEINS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE SILENCING; INTERFERON TYPE II; INTERLEUKIN-17; MICE; MULTIPLE SCLEROSIS; RETROVIRIDAE; RNA, SMALL INTERFERING; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC; UP-REGULATION;

ANIMALIA; MUS;

EID: 46149104979     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803454105     Document Type: Article

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