Degradation of IκBα in activated RAW264.7 cells is blocked by the phosphatidylinositol 3-kinase inhibitor LY294002

Cell Biology and Toxicology

Volumn 18, Issue 2, 2002, Pages 121-130

  Park, S J ^a   Lee, S C ^a   Hong, S H ^a   Kim, Hyung Min ^a  

^a Wonkwang University   (South Korea)

Author keywords

2 (4 morpholinyl) 8 phenylchromone; Lipopolysaccharide; Phorbol 12 myristate 13 acetate; Phosphatidylinositol 3 kinase; RAW264.7 cells

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GAMMA INTERFERON; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; I KAPPA B; MORPHOLINE DERIVATIVE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PRIMER DNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; IMMUNOREGULATION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HYDROLYSIS; METABOLISM; NUCLEOTIDE SEQUENCE;

ANIMALIA; MURINAE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CHROMONES; DNA PRIMERS; DNA-BINDING PROTEINS; HYDROLYSIS; I-KAPPA B PROTEINS; INTERFERON TYPE II; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MORPHOLINES; NITRIC OXIDE; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036013435     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015384201785     Document Type: Article

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