-
1
-
-
84937683260
-
-
[Last accessed 15 March 2015]
-
World Cancer Research Fund International. Worldwide data. 2015. Available from: www.wcrf.org/int/cancer-facts-figures/wordwide-data [Last accessed 15 March 2015]
-
(2015)
-
-
World Cancer Research Fund International1
-
2
-
-
0013039863
-
-
[Last accessed 15 March 2015]
-
Top ten cancers in 2012. Hong Kong Cancer Registry 2012. Available from: www3.ha.org.hk/cancereg/statistics.html [Last accessed 15 March 2015]
-
(2012)
Hong Kong Cancer Registry
-
-
-
3
-
-
84884199802
-
Quantifying the burden of disease due to premature mortality in Hong Kong using standard expected years of life lost
-
Plass D, Chau PY, Thach TQ, et al. Quantifying the burden of disease due to premature mortality in Hong Kong using standard expected years of life lost. BMC Public Health 2013;13:863
-
(2013)
BMC Public Health
, vol.13
, pp. 863
-
-
Plass, D.1
Chau, P.Y.2
Thach, T.Q.3
-
4
-
-
84896728477
-
Smoky coal, tobacco smoking, and lung cancer risk in Xuanwei, China
-
Kim C, Chapman RS, Hu W, et al. Smoky coal, tobacco smoking, and lung cancer risk in Xuanwei, China. Lung Cancer 2014;84: 31-5
-
(2014)
Lung Cancer
, vol.84
, pp. 31-35
-
-
Kim, C.1
Chapman, R.S.2
Hu, W.3
-
5
-
-
33646390663
-
Dose-response relationship between cooking fumes exposures and lung cancer among Chinese nonsmoking women
-
Yu IT, Chiu YL, Au JS, et al. Dose-response relationship between cooking fumes exposures and lung cancer among Chinese nonsmoking women. Cancer Res 2006;66:4961-7
-
(2006)
Cancer Res
, vol.66
, pp. 4961-4967
-
-
Yu, I.T.1
Chiu, Y.L.2
Au, J.S.3
-
6
-
-
84874045136
-
Residential radon and lung cancer risk: An updated meta-analysis of case-control studies
-
Zhang ZL, Sun J, Dong JY, et al. Residential radon and lung cancer risk: an updated meta-analysis of case-control studies. Asian Pac J Cancer Prev 2012;13: 2459-65
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 2459-2465
-
-
Zhang, Z.L.1
Sun, J.2
Dong, J.Y.3
-
8
-
-
70449512553
-
Measles virus: Evidence for association with lung cancer
-
Sion-Vardy N, Lasarov I, Delgado B, et al. Measles virus: evidence for association with lung cancer. Exp Lung Res 2009;35:701-12
-
(2009)
Exp Lung Res
, vol.35
, pp. 701-712
-
-
Sion-Vardy, N.1
Lasarov, I.2
Delgado, B.3
-
9
-
-
84873151479
-
Family history of lung cancer in never smokers with non-small-cell lung cancer and its association with tumors harboring EGFR mutations
-
Gaughan EM, Cryer SK, Yeap BY, et al. Family history of lung cancer in never smokers with non-small-cell lung cancer and its association with tumors harboring EGFR mutations. Lung Cancer 2013;79:193-7
-
(2013)
Lung Cancer
, vol.79
, pp. 193-197
-
-
Gaughan, E.M.1
Cryer, S.K.2
Yeap, B.Y.3
-
10
-
-
84879274070
-
Maintenance therapy in advanced non-small cell lung cancer: A prime-time for change?
-
Chan OS, Yeung RM and Lee AW. Maintenance therapy in advanced non-small cell lung cancer: a prime-time for change? Chin Med J (Engl) 2013;126:2390-8
-
(2013)
Chin Med J (Engl)
, vol.126
, pp. 2390-2398
-
-
Chan, O.S.1
Yeung, R.M.2
Lee, A.W.3
-
11
-
-
79958043675
-
-
National Cancer Institute. Bethesda, MD Last accessed 15 March
-
Howlader N, Noone AM, Krapcho M, et al. SEER Cancer Statistics Review, 1975-2010. National Cancer Institute. Bethesda, MD. Available from: http://seer. cancer.gov/csr/1975-2010/[Last accessed 15 March 2014]
-
(2014)
SEER Cancer Statistics Review, 1975-2010
-
-
Howlader, N.1
Noone, A.M.2
Krapcho, M.3
-
12
-
-
84882943447
-
Prospects for population screening and diagnosis of lung cancer
-
Field JK, Oudkerk M, Pedersen JH, et al. Prospects for population screening and diagnosis of lung cancer. Lancet 2013;382: 732-41
-
(2013)
Lancet
, vol.382
, pp. 732-741
-
-
Field, J.K.1
Oudkerk, M.2
Pedersen, J.H.3
-
13
-
-
70349376330
-
Molecular predictive and prognostic markers in non-small-cell lung cancer
-
Coate LE, John T, Tsao MS, et al. Molecular predictive and prognostic markers in non-small-cell lung cancer. Lancet Oncol 2009;10:1001-10
-
(2009)
Lancet Oncol
, vol.10
, pp. 1001-1010
-
-
Coate, L.E.1
John, T.2
Tsao, M.S.3
-
14
-
-
84882977045
-
Genetics and biomarkers in personalisation of lung cancer treatment
-
Rosell R, Bivona TG, Karachaliou N. Genetics and biomarkers in personalisation of lung cancer treatment. Lancet 2013;382: 720-31
-
(2013)
Lancet
, vol.382
, pp. 720-731
-
-
Rosell, R.1
Bivona, T.G.2
Karachaliou, N.3
-
16
-
-
79551563284
-
International association for the study of lung cancer/American thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
-
Travis WD, Brambilla E, Noguchi M, et al. International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 2011;6: 244-85
-
(2011)
J Thorac Oncol
, vol.6
, pp. 244-285
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
-
17
-
-
25644461068
-
International lung cancer trends by histologic type: Male:female differences diminishing and adenocarcinoma rates rising
-
Devesa SS, Bray F, Vizcaino AP, et al. International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. Int J Cancer 2005;117:294-9
-
(2005)
Int J Cancer
, vol.117
, pp. 294-299
-
-
Devesa, S.S.1
Bray, F.2
Vizcaino, A.P.3
-
18
-
-
33846187218
-
Update on epidermal growth factor receptor mutations in non-small cell lung cancer
-
Riely GJ, Politi KA, Miller VA, et al. Update on epidermal growth factor receptor mutations in non-small cell lung cancer. Clin Cancer Res 2006;12:7232-41
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7232-7241
-
-
Riely, G.J.1
Politi, K.A.2
Miller, V.A.3
-
21
-
-
84874606355
-
EGFR mutation testing in lung cancer: A review of available methods and their use for analysis of tumour tissue and cytology samples
-
Ellison G, Zhu G, Moulis A, et al. EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples. J Clin Pathol 2013;66:79-89
-
(2013)
J Clin Pathol
, vol.66
, pp. 79-89
-
-
Ellison, G.1
Zhu, G.2
Moulis, A.3
-
22
-
-
84879635389
-
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: Guideline from the college of American pathologists, international association for the study of lung cancer, and association for molecular pathology
-
Lindeman NI, Cagle PT, Beasley MB, et al. Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the college of American pathologists, international association for the study of lung cancer, and association for molecular pathology. Arch Pathol Lab Med 2013;137: 828-60
-
(2013)
Arch Pathol Lab Med
, vol.137
, pp. 828-860
-
-
Lindeman, N.I.1
Cagle, P.T.2
Beasley, M.B.3
-
23
-
-
84894611641
-
Guideline recommendations for testing of ALK gene rearrangement in lung cancer: A proposal of the Korean Cardiopulmonary Pathology Study Group
-
Kim H, Shim HS, Kim L, et al. Guideline recommendations for testing of ALK gene rearrangement in lung cancer: a proposal of the Korean Cardiopulmonary Pathology Study Group. Korean J Pathol 2014;48:1-9
-
(2014)
Korean J Pathol
, vol.48
, pp. 1-9
-
-
Kim, H.1
Shim, H.S.2
Kim, L.3
-
24
-
-
84862893803
-
EGFR array: Uses in the detection of plasma EGFR mutations in non-small cell lung cancer patients
-
Yam I, Lam DC, Chan K, et al. EGFR array: uses in the detection of plasma EGFR mutations in non-small cell lung cancer patients. J Thorac Oncol 2012;7:1131-40
-
(2012)
J Thorac Oncol
, vol.7
, pp. 1131-1140
-
-
Yam, I.1
Lam, D.C.2
Chan, K.3
-
25
-
-
74949117339
-
Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer
-
Dahabreh IJ, Linardou H, Siannis F, et al. Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res 2010;16: 291-303
-
(2010)
Clin Cancer Res
, vol.16
, pp. 291-303
-
-
Dahabreh, I.J.1
Linardou, H.2
Siannis, F.3
-
27
-
-
84857087591
-
Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: Lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations
-
Rekhtman N, Paik PK, Arcila ME, et al. Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations. Clin Cancer Res 2012;18:1167-76
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1167-1176
-
-
Rekhtman, N.1
Paik, P.K.2
Arcila, M.E.3
-
28
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350: 2129-39
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
29
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-57
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
30
-
-
84902014209
-
Effectiveness and cost-effectiveness of erlotinib versus gefitinib in first-line treatment of epidermal growth factor receptor-activating mutation-positive non-small-cell lung cancer patients in Hong Kong
-
Lee VW, Schwander B, Lee VH. Effectiveness and cost-effectiveness of erlotinib versus gefitinib in first-line treatment of epidermal growth factor receptor-activating mutation-positive non-small-cell lung cancer patients in Hong Kong. Hong Kong Med J 2014;20:178-86
-
(2014)
Hong Kong Med J
, vol.20
, pp. 178-186
-
-
Lee, V.W.1
Schwander, B.2
Lee, V.H.3
-
31
-
-
80052437758
-
New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer
-
Oxnard GR, Arcila ME, Chmielecki J, et al. New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer. Clin Cancer Res 2011;17:5530-7
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5530-5537
-
-
Oxnard, G.R.1
Arcila, M.E.2
Chmielecki, J.3
-
32
-
-
63449103435
-
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients
-
Yung TK, Chan KC, Mok TS, et al. Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients. Clin Cancer Res 2009;15:2076-84
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2076-2084
-
-
Yung, T.K.1
Chan, K.C.2
Mok, T.S.3
-
33
-
-
80053620308
-
A novel method for detection of mutation in epidermal growth factor receptor
-
Zhao J, Zhao J, Huang J, et al. A novel method for detection of mutation in epidermal growth factor receptor. Lung Cancer 2011;74:226-32
-
(2011)
Lung Cancer
, vol.74
, pp. 226-232
-
-
Zhao, J.1
Zhao, J.2
Huang, J.3
-
34
-
-
84937723142
-
-
Last accessed 15 March
-
QIAGEN. Product Page: Therascreen EGFR Pyro Kit. Available from: www.qiagen.com/Products/Catalog/Assay-Technologies/Complete-Assay-Kits/Personalized-Healthcare/therascreen-EGFRPyro-Kit#orderinginformation [Last accessed 15 March 2014]
-
(2014)
Product Page: Therascreen EGFR Pyro Kit
-
-
-
35
-
-
84937707297
-
-
Last accessed 15 March
-
Roche molecular diagnostic. Product: Cobas EGFR mutation Test. Available from: http://molecular.roche.com/assays/Pages/cobasEGFRMutationTest.aspx [Last accessed 15 March 2014]
-
(2014)
Product: Cobas EGFR Mutation Test
-
-
-
36
-
-
84883446951
-
Evaluation of 2 real-time PCR assays for in vitro diagnostic use in the rapid and multiplex detection of EGFR gene mutations in NSCLC
-
Wong AT, To RM, Wong CL, et al. Evaluation of 2 real-time PCR assays for in vitro diagnostic use in the rapid and multiplex detection of EGFR gene mutations in NSCLC. Diagn Mol Pathol 2013;22:138-43
-
(2013)
Diagn Mol Pathol
, vol.22
, pp. 138-143
-
-
Wong, A.T.1
To, R.M.2
Wong, C.L.3
-
37
-
-
84883378283
-
Association of exon 19 and 21 EGFR mutation patterns with treatment outcome after first-line tyrosine kinase inhibitor in metastatic non-small-cell lung cancer
-
Lee VH, Tin VP, Choy TS, et al. Association of exon 19 and 21 EGFR mutation patterns with treatment outcome after first-line tyrosine kinase inhibitor in metastatic non-small-cell lung cancer. J Thorac Oncol 2013;8:1148-55
-
(2013)
J Thorac Oncol
, vol.8
, pp. 1148-1155
-
-
Lee, V.H.1
Tin, V.P.2
Choy, T.S.3
-
38
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 2009;27:4247-53
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
39
-
-
79251490374
-
New driver mutations in non-small-cell lung cancer
-
Pao W, Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 2011;12:175-80
-
(2011)
Lancet Oncol
, vol.12
, pp. 175-180
-
-
Pao, W.1
Girard, N.2
-
40
-
-
84881256393
-
ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: An analysis of 1,683 patients with non-small cell lung cancer
-
Gainor JF, Varghese AM, Ou SH, et al. ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer. Clin Cancer Res 2013;19: 4273-81
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4273-4281
-
-
Gainor, J.F.1
Varghese, A.M.2
Ou, S.H.3
-
41
-
-
84898936879
-
U.S. Food and drug administration approval: Crizotinib for treatment of advanced or metastatic non-small cell lung cancer that is anaplastic lymphoma kinase positive
-
Malik SM, Maher VE, Bijwaard KE, et al. U.S. Food and Drug Administration Approval: Crizotinib for Treatment of Advanced or Metastatic Non-small Cell Lung Cancer that Is Anaplastic Lymphoma Kinase Positive. Clin Cancer Res 2014;20: 2029-34
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2029-2034
-
-
Malik, S.M.1
Maher, V.E.2
Bijwaard, K.E.3
-
42
-
-
84856999699
-
Mechanisms of acquired crizotinib resistance in ALK rearranged lung cancers
-
Katayama R, Shaw AT, Khan TM, et al. Mechanisms of acquired crizotinib resistance in ALK rearranged lung cancers. Sci Transl Med 2012;4(120):120ra17
-
(2012)
Sci Transl Med
, vol.4
, Issue.120
, pp. 120ra17
-
-
Katayama, R.1
Shaw, A.T.2
Khan, T.M.3
-
43
-
-
84856990335
-
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer
-
Doebele RC, Pilling AB, Aisner DL, et al. Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer. Clin Cancer Res 2012;18:1472-82
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1472-1482
-
-
Doebele, R.C.1
Pilling, A.B.2
Aisner, D.L.3
-
44
-
-
84874586164
-
Targeted resequencing reveals ALK fusions in non-small cell lung carcinomas detected by FISH, immunohistochemistry, and real-time RT-PCR: A comparison of four methods
-
Tuononen K, Sarhadi VK, Wirtanen A, et al. Targeted resequencing reveals ALK fusions in non-small cell lung carcinomas detected by FISH, immunohistochemistry, and real-time RT-PCR: a comparison of four methods. Biomed Res Int 2013;2013:757490
-
(2013)
Biomed Res Int
, vol.2013
, pp. 757490
-
-
Tuononen, K.1
Sarhadi, V.K.2
Wirtanen, A.3
-
45
-
-
84880917013
-
Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant
-
To KF, Tong JH, Yeung KS, et al. Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant. J Thorac Oncol 2013;8:883-91
-
(2013)
J Thorac Oncol
, vol.8
, pp. 883-891
-
-
To, K.F.1
Tong, J.H.2
Yeung, K.S.3
-
46
-
-
77649308276
-
High MET gene copy number leads to shorter survival in patients with non-small cell lung cancer
-
Go H, Jeon YK, Park HJ, et al. High MET gene copy number leads to shorter survival in patients with non-small cell lung cancer. J Thorac Oncol 2010;3:305-13
-
(2010)
J Thorac Oncol
, vol.3
, pp. 305-313
-
-
Go, H.1
Jeon, Y.K.2
Park, H.J.3
-
47
-
-
63849163410
-
Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
-
Cappuzzo F, Marchetti A, Skokan M, et al. Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients. J Clin Oncol 2009;27:1667-74
-
(2009)
J Clin Oncol
, vol.27
, pp. 1667-1674
-
-
Cappuzzo, F.1
Marchetti, A.2
Skokan, M.3
-
48
-
-
80051974548
-
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
-
Sequist LV, von Pawel J, Garmey EG, et al. Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. J Clin Oncol 2011;29:3307-15
-
(2011)
J Clin Oncol
, vol.29
, pp. 3307-3315
-
-
Sequist, L.V.1
Von Pawel, J.2
Garmey, E.G.3
-
49
-
-
84890108571
-
Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer
-
Spigel DR, Ervin TJ, Ramlau RA, et al. Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol 2013;31:4105-14
-
(2013)
J Clin Oncol
, vol.31
, pp. 4105-4114
-
-
Spigel, D.R.1
Ervin, T.J.2
Ramlau, R.A.3
-
50
-
-
84881245421
-
Molecular pathways: ROS1 fusion in cancer
-
Davies KD, Doebele RC. Molecular pathways: ROS1 fusion in cancer. Clin Cancer Res 2013;15:4040-5
-
(2013)
Clin Cancer Res
, vol.15
, pp. 4040-4045
-
-
Davies, K.D.1
Doebele, R.C.2
-
51
-
-
84928690791
-
The Dual ALK/EGFR Inhibitor AP26113 also potently inhibits activated and gatekeeper mutant forms of ROS1
-
Anjum R, Zhang S, Squillace R, et al. The Dual ALK/EGFR Inhibitor AP26113 also potently inhibits activated and gatekeeper mutant forms of ROS1. Eur J Cancer 2012;48:50
-
(2012)
Eur J Cancer
, vol.48
, pp. 50
-
-
Anjum, R.1
Zhang, S.2
Squillace, R.3
-
52
-
-
84865092224
-
Clinical activity of crizotinib in advanced non-small cell lung cancer (NSCLC) harboring ROS1 gene rearrangement
-
Shaw AT, Camidge DR, Engelman JA, et al. Clinical activity of crizotinib in advanced non-small cell lung cancer (NSCLC) harboring ROS1 gene rearrangement. J Clin Oncol 2012; 30(Suppl):abstract 7508
-
(2012)
J Clin Oncol
, vol.30
-
-
Shaw, A.T.1
Camidge, D.R.2
Engelman, J.A.3
-
53
-
-
84905117717
-
Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors
-
Park BS, Al-Sanea MM, Abdelazem AZ, et al. Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors. Bioorg Med Chem 2014;22:3871-8
-
(2014)
Bioorg Med Chem
, vol.22
, pp. 3871-3878
-
-
Park, B.S.1
Al-Sanea, M.M.2
Abdelazem, A.Z.3
-
55
-
-
84892875156
-
On the relevance of a testing algorithm for the detection of ROS1-rearranged lung adenocarcinomas
-
Mescam-Mancini L, Lantuejoul S, Sibilot DM, et al. On the relevance of a testing algorithm for the detection of ROS1-rearranged lung adenocarcinomas. Lung Cancer 2014;83:168-73
-
(2014)
Lung Cancer
, vol.83
, pp. 168-173
-
-
Mescam-Mancini, L.1
Lantuejoul, S.2
Sibilot, D.M.3
-
56
-
-
34249810645
-
KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Massarelli E, Varella-Garcia M, Tang X, et al. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 2007;13:2890-6
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2890-2896
-
-
Massarelli, E.1
Varella-Garcia, M.2
Tang, X.3
-
57
-
-
84880922207
-
EGFR and KRAS mutational profiling in fresh non-small cell lung cancer (NSCLC) cells
-
Stella GM, Scabini R, Inghilleri S, et al. EGFR and KRAS mutational profiling in fresh non-small cell lung cancer (NSCLC) cells. J Cancer Res Clin Oncol 2013;139: 1327-35
-
(2013)
J Cancer Res Clin Oncol
, vol.139
, pp. 1327-1335
-
-
Stella, G.M.1
Scabini, R.2
Inghilleri, S.3
-
58
-
-
84871720411
-
Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: A randomised, multicentre, placebo-controlled, phase 2 study
-
Jänne PA, Shaw AT, Pereira JR, et al. Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study. Lancet Oncol 2013;14(1):38-47
-
(2013)
Lancet Oncol
, vol.14
, Issue.1
, pp. 38-47
-
-
Jänne, P.A.1
Shaw, A.T.2
Pereira, J.R.3
-
59
-
-
84937696070
-
-
Last accessed 15 March
-
QIAGEN. Product Page: Therascreen KRAS Pyro Kit. Available from: www.qiagen.com/products/catalog/assaytechnologies/complete-assay-kits/personalized-healthcare/therascreen-kraspyro-kit [Last accessed 15 March 2014]
-
(2014)
Product Page: Therascreen KRAS Pyro Kit
-
-
-
60
-
-
84937708678
-
-
Last accessed 15 March
-
Roche molecular diagnostic. Product: TheraScreen KRAS mutation Kit. Available from: www.oem-info.com/roche/handbooks/data/DU001g-KRAS-TheraScreen-ENGLISH. pdf [Last accessed 15 March 2014]
-
(2014)
Product: TheraScreen KRAS Mutation Kit
-
-
-
61
-
-
84937688528
-
-
Last accessed 15 March
-
Oasia Diagnostics. Genomics Products. Available from: http://4saliva.com/genomics/k-ras/[Last accessed 15 March 2014]
-
(2014)
Genomics Products
-
-
Oasia Diagnostics1
-
63
-
-
84919969088
-
BRAF vs RAS oncogenes: Are mutations of the same pathway equal? Differential signalling and therapeutic implications
-
Oikonomou E, Koustas E, Goulielmaki M, et al. BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications. Oncotarget 2014;5:11752-77
-
(2014)
Oncotarget
, vol.5
, pp. 11752-11777
-
-
Oikonomou, E.1
Koustas, E.2
Goulielmaki, M.3
-
64
-
-
84924054240
-
Targeting HER2 in the treatment of non-small cell lung cancer
-
Mar N, Vredenburgh JJ, Wasser JS. Targeting HER2 in the treatment of non-small cell lung cancer. Lung Cancer 2015;87:220-5
-
(2015)
Lung Cancer
, vol.87
, pp. 220-225
-
-
Mar, N.1
Vredenburgh, J.J.2
Wasser, J.S.3
-
65
-
-
84880661427
-
Lung cancer that harbors an HER2 mutation: Epidemiologic characteristics and therapeutic perspectives
-
Mazières J, Peters S, Lepage B, et al. Lung cancer that harbors an HER2 mutation: epidemiologic characteristics and therapeutic perspectives. J Clin Oncol 2013;31: 1997-2003
-
(2013)
J Clin Oncol
, vol.31
, pp. 1997-2003
-
-
Mazières, J.1
Peters, S.2
Lepage, B.3
-
66
-
-
84880664490
-
Novel targets in non-small cell lung cancer: ROS1 and RET fusions
-
Gainor JF, Shaw AT. Novel targets in non-small cell lung cancer: ROS1 and RET fusions. Oncologist 2013;18:865-75
-
(2013)
Oncologist
, vol.18
, pp. 865-875
-
-
Gainor, J.F.1
Shaw, A.T.2
-
67
-
-
84870748688
-
RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer
-
Wang R, Hu H, Pan Y, et al. RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer. J Clin Oncol 2012;30:4352-9
-
(2012)
J Clin Oncol
, vol.30
, pp. 4352-4359
-
-
Wang, R.1
Hu, H.2
Pan, Y.3
-
68
-
-
84878858856
-
Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas
-
Drilon A, Wang L, Hasanovic A, et al. Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas. Cancer Discov 2013;3:630-5
-
(2013)
Cancer Discov
, vol.3
, pp. 630-635
-
-
Drilon, A.1
Wang, L.2
Hasanovic, A.3
-
69
-
-
79955667838
-
Targeting mutant fibroblast growth factor receptors in cancer
-
Greulich H, Pollock PM. Targeting mutant fibroblast growth factor receptors in cancer. Trends Mol Med 2011;17:283-92
-
(2011)
Trends Mol Med
, vol.17
, pp. 283-292
-
-
Greulich, H.1
Pollock, P.M.2
-
70
-
-
84856295103
-
Increased FGFR1 copy number in lung squamous cell carcinomas
-
Sasaki H, Shitara M, Yokota K, et al. Increased FGFR1 copy number in lung squamous cell carcinomas. Mol Med Rep 2012;5:725-8
-
(2012)
Mol Med Rep
, vol.5
, pp. 725-728
-
-
Sasaki, H.1
Shitara, M.2
Yokota, K.3
-
71
-
-
84864277372
-
FGFR1 expression and gene copy numbers in human lung cancer
-
Kohler LH, MIReskandari M, Knösel T, et al. FGFR1 expression and gene copy numbers in human lung cancer. Virchows Arch 2012;461:49-57
-
(2012)
Virchows Arch
, vol.461
, pp. 49-57
-
-
Kohler, L.H.1
MIReskandari, M.2
Knösel, T.3
-
72
-
-
79958112619
-
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer
-
Dutt A, Ramos AH, Hammerman PS, et al. Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. PLoS One 2011;6:e20351
-
(2011)
PLoS One
, vol.6
, pp. e20351
-
-
Dutt, A.1
Ramos, A.H.2
Hammerman, P.S.3
-
73
-
-
84874888512
-
Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer
-
Kim HR, Kim DJ, Kang DR, et al. Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer. J Clin Oncol 2013;31:731-7
-
(2013)
J Clin Oncol
, vol.31
, pp. 731-737
-
-
Kim, H.R.1
Kim, D.J.2
Kang, D.R.3
-
74
-
-
84925285873
-
FGFR1 amplification is associated with poor prognosis and smoking in non-small-cell lung cancer
-
Seo AN, Jin Y, Lee HJ, et al. FGFR1 amplification is associated with poor prognosis and smoking in non-small-cell lung cancer. Virchows Arch 2014;465:547-58
-
(2014)
Virchows Arch
, vol.465
, pp. 547-558
-
-
Seo, A.N.1
Jin, Y.2
Lee, H.J.3
-
75
-
-
84902548159
-
Prognostic role of FGFR1 amplification in early-stage non-small cell lung cancer
-
Cihoric N, Savic S, Schneider S, et al. Prognostic role of FGFR1 amplification in early-stage non-small cell lung cancer. Br J Cancer 2014;110:2914-22
-
(2014)
Br J Cancer
, vol.110
, pp. 2914-2922
-
-
Cihoric, N.1
Savic, S.2
Schneider, S.3
-
76
-
-
84876240753
-
Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1
-
Ren M, Hong M, Liu G, et al. Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1. Oncol Rep 2013;29: 2181-90
-
(2013)
Oncol Rep
, vol.29
, pp. 2181-2190
-
-
Ren, M.1
Hong, M.2
Liu, G.3
-
77
-
-
84900340780
-
Discoidin domain receptors in disease
-
Borza CM, Pozzi A. Discoidin domain receptors in disease. Matrix Biol 2014;34: 185-92
-
(2014)
Matrix Biol
, vol.34
, pp. 185-192
-
-
Borza, C.M.1
Pozzi, A.2
-
78
-
-
84866709500
-
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
-
Hammerman PS, Sos ML, Ramos AH, et al. Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer. Cancer Discov 2011;1:78-89
-
(2011)
Cancer Discov
, vol.1
, pp. 78-89
-
-
Hammerman, P.S.1
Sos, M.L.2
Ramos, A.H.3
-
79
-
-
84901616155
-
Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients
-
Miao L, Wang Y, Zhu S, et al. Identification of novel driver mutations of the discoidin domain receptor 2 (DDR2) gene in squamous cell lung cancer of Chinese patients. BMC Cancer 2014;14:369
-
(2014)
BMC Cancer
, vol.14
, pp. 369
-
-
Miao, L.1
Wang, Y.2
Zhu, S.3
-
80
-
-
84890297953
-
Phosphatase and tensin homologue deleted on chromosome
-
Abdulkareem IH, Blair M. Phosphatase and tensin homologue deleted on chromosome. Niger Med J 2013;54:79-86
-
(2013)
Niger Med J
, vol.54
, pp. 79-86
-
-
Abdulkareem, I.H.1
Blair, M.2
-
81
-
-
78449283888
-
Loss of PTEN expression by blocking nuclear translocation of EGR1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-activating mutations
-
Yamamoto C, Basaki Y, Kawahara A, et al. Loss of PTEN expression by blocking nuclear translocation of EGR1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-activating mutations. Cancer Res 2010;70:8715-25
-
(2010)
Cancer Res
, vol.70
, pp. 8715-8725
-
-
Yamamoto, C.1
Basaki, Y.2
Kawahara, A.3
-
82
-
-
84875518717
-
Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency
-
Takeda H, Takigawa N, Ohashi K, et al. Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency. Exp Cell Res 2013;319:417-23
-
(2013)
Exp Cell Res
, vol.319
, pp. 417-423
-
-
Takeda, H.1
Takigawa, N.2
Ohashi, K.3
-
83
-
-
79952108510
-
Oncogenic mutations of PIK3CA in human cancers
-
Samuels Y, Waldman T. Oncogenic mutations of PIK3CA in human cancers. Curr Top Microbiol Immunol 2010;347: 21-41
-
(2010)
Curr Top Microbiol Immunol
, vol.347
, pp. 21-41
-
-
Samuels, Y.1
Waldman, T.2
-
84
-
-
84887942578
-
Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics
-
Akinleye A, Avvaru P, Furqan M, et al. Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics. J Hematol Oncol 2013;6:88
-
(2013)
J Hematol Oncol
, vol.6
, pp. 88
-
-
Akinleye, A.1
Avvaru, P.2
Furqan, M.3
-
85
-
-
84885816283
-
Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer
-
Niederst MJ, Engelman JA. Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer. Sci Signal 2013;6:re6
-
(2013)
Sci Signal
, vol.6
, pp. re6
-
-
Niederst, M.J.1
Engelman, J.A.2
-
86
-
-
84922349096
-
The phosphoinositide 3-kinase pathway and therapy resistance in cancer
-
Brown KK, Toker A. The phosphoinositide 3-kinase pathway and therapy resistance in cancer. F1000Prime Rep 2015;7:13
-
(2015)
F1000Prime Rep
, vol.7
, pp. 13
-
-
Brown, K.K.1
Toker, A.2
-
87
-
-
84893249799
-
PI3K and cancer: Lessons, challenges and opportunities
-
Fruman DA, Rommel C. PI3K and cancer: lessons, challenges and opportunities. Nat Rev Drug Discov 2014;13:140-56
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 140-156
-
-
Fruman, D.A.1
Rommel, C.2
-
88
-
-
84879677951
-
A novel imidazopyridine PI3K inhibitor with anticancer activity in non-small cell lung cancer cells
-
Lee H, Kim SJ, Jung KH. A novel imidazopyridine PI3K inhibitor with anticancer activity in non-small cell lung cancer cells. Oncol Rep 2013;30:863-9
-
(2013)
Oncol Rep
, vol.30
, pp. 863-869
-
-
Lee, H.1
Kim, S.J.2
Jung, K.H.3
-
89
-
-
84874081147
-
Endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer: The first experience in Hong Kong
-
Wong MK, Ho JC, Loong F, et al. Endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer: the first experience in Hong Kong. Hong Kong Med J 2013;19:20-6
-
(2013)
Hong Kong Med J
, vol.19
, pp. 20-26
-
-
Wong, M.K.1
Ho, J.C.2
Loong, F.3
-
90
-
-
84901920157
-
EBUS-TBNA provides highest RNA yield for multiple biomarker testing from routinely obtained small biopsies in non-small cell lung cancer patients-A comparative study of three different minimal invasive sampling methods
-
Schmid-Bindert G, Wang Y, Jiang H, et al. EBUS-TBNA provides highest RNA yield for multiple biomarker testing from routinely obtained small biopsies in non-small cell lung cancer patients-a comparative study of three different minimal invasive sampling methods. PLoS One 2013;8:e77948
-
(2013)
PLoS One
, vol.8
, pp. e77948
-
-
Schmid-Bindert, G.1
Wang, Y.2
Jiang, H.3
-
91
-
-
84872020299
-
Cancer genome scanning in plasma: Detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
-
Chan KC, Jiang P, Zheng YW, et al. Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing. Clin Chem 2013;59:211-24
-
(2013)
Clin Chem
, vol.59
, pp. 211-224
-
-
Chan, K.C.1
Jiang, P.2
Zheng, Y.W.3
-
92
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
93
-
-
84860238222
-
Applications of MicroRNAs in the Diagnosis and prognosis of Lung Cancer
-
Shen J, Jiang F. Applications of MicroRNAs in the Diagnosis and prognosis of Lung Cancer. Expert Opin Med Diagn 2012;6: 197-207
-
(2012)
Expert Opin Med Diagn
, vol.6
, pp. 197-207
-
-
Shen, J.1
Jiang, F.2
-
94
-
-
84863429647
-
MicroRNAs and lung cancers: From pathogenesis to clinical implications
-
Qi J, Mu D. MicroRNAs and lung cancers: from pathogenesis to clinical implications. Front Med 2012;6:134-55
-
(2012)
Front Med
, vol.6
, pp. 134-155
-
-
Qi, J.1
Mu, D.2
-
95
-
-
84937683174
-
-
Last accessed 15 March
-
MIRBase. Available from: www.MIRbase.org [Last accessed 15 March 2014]
-
(2014)
-
-
-
96
-
-
84885029680
-
MicroRNAs as molecular targets for cancer therapy: On the modulation of microRNA expression
-
Costa PM, Pedroso de Lima MC. MicroRNAs as molecular targets for cancer therapy: on the modulation of microRNA expression. Pharmaceuticals (Basel) 2013;6:1195-220
-
(2013)
Pharmaceuticals (Basel)
, vol.6
, pp. 1195-1220
-
-
Costa, P.M.1
Pedroso De Lima, M.C.2
-
97
-
-
84883140244
-
Molecular sputum analysis for the diagnosis of lung cancer
-
Hubers AJ, Prinsen CF, Sozzi G, et al. Molecular sputum analysis for the diagnosis of lung cancer. Br J Cancer 2013;109:530-7
-
(2013)
Br J Cancer
, vol.109
, pp. 530-537
-
-
Hubers, A.J.1
Prinsen, C.F.2
Sozzi, G.3
-
98
-
-
1842585925
-
Quantification of plasma beta-catenin mRNA in colorectal cancer and adenoma patients
-
Wong SC, Lo SF, Cheung MT, et al. Quantification of plasma beta-catenin mRNA in colorectal cancer and adenoma patients. Clin Cancer Res 2004;10:1613-17
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1613-1617
-
-
Wong, S.C.1
Lo, S.F.2
Cheung, M.T.3
-
99
-
-
84901700596
-
MRNA and MIRNA analyses in cytologically positive endobronchial ultrasound-guided transbronchial needle aspiration: Implications for molecular staging in lung cancer patients
-
Plönes T, Elze M, Kayser G, et al. mRNA and MIRNA analyses in cytologically positive endobronchial ultrasound-guided transbronchial needle aspiration: Implications for molecular staging in lung cancer patients. Cancer Cytopathol 2014;122:292-8
-
(2014)
Cancer Cytopathol
, vol.122
, pp. 292-298
-
-
Plönes, T.1
Elze, M.2
Kayser, G.3
-
100
-
-
84859464569
-
Blood cell origin of circulating microRNAs: A cautionary note for cancer biomarker studies
-
Pritchard CC, Kroh E, Wood B, et al. Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev Res (Phila) 2012;5: 492-7
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 492-497
-
-
Pritchard, C.C.1
Kroh, E.2
Wood, B.3
-
101
-
-
84863415612
-
Serum microRNA biomarkers for detection of non-small cell lung cancer
-
Hennessey PT, Sanford T, Choudhary A, et al. Serum microRNA biomarkers for detection of non-small cell lung cancer. PLoS One 2012;7:e32307
-
(2012)
PLoS One
, vol.7
, pp. e32307
-
-
Hennessey, P.T.1
Sanford, T.2
Choudhary, A.3
-
102
-
-
84860261087
-
High expression of serum MIR-21 and tumor MIR-200c associated with poor prognosis in patients with lung cancer
-
Liu XG, Zhu WY, Huang YY, et al. High expression of serum MIR-21 and tumor MIR-200c associated with poor prognosis in patients with lung cancer. Med Oncol 2012;29:618-26
-
(2012)
Med Oncol
, vol.29
, pp. 618-626
-
-
Liu, X.G.1
Zhu, W.Y.2
Huang, Y.Y.3
-
103
-
-
79960957682
-
A serum circulating MIRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer
-
Bianchi L, Nicassio F, Marzi M, et al. A serum circulating MIRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer. EMBO Mol Med 2011;3:495-503
-
(2011)
EMBO Mol Med
, vol.3
, pp. 495-503
-
-
Bianchi, L.1
Nicassio, F.2
Marzi, M.3
-
104
-
-
84862205836
-
Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation
-
Whale AS, Huggett JF, Cowen S, et al. Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation. Nucleic Acids Res 2012;40:e82
-
(2012)
Nucleic Acids Res
, vol.40
, pp. e82
-
-
Whale, A.S.1
Huggett, J.F.2
Cowen, S.3
-
105
-
-
84887629698
-
Quantification of plasma MIRNAs by digital PCR for cancer diagnosis
-
Ma J, Li N, Guarnera M, et al. Quantification of plasma MIRNAs by digital PCR for cancer diagnosis. Biomark Insights 2013;8:127-36
-
(2013)
Biomark Insights
, vol.8
, pp. 127-136
-
-
Ma, J.1
Li, N.2
Guarnera, M.3
-
106
-
-
58149399844
-
Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer
-
Daskalos A, Nikolaidis G, Xinarianos G, et al. Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer 2009;124:81-7
-
(2009)
Int J Cancer
, vol.124
, pp. 81-87
-
-
Daskalos, A.1
Nikolaidis, G.2
Xinarianos, G.3
-
107
-
-
33847373449
-
The role of DNA methylation in the development and progression of lung adenocarcinoma
-
Kerr KM, Galler JS, Hagen JA, et al. The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers 2007;23:5-30
-
(2007)
Dis Markers
, vol.23
, pp. 5-30
-
-
Kerr, K.M.1
Galler, J.S.2
Hagen, J.A.3
-
109
-
-
84857159930
-
Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates
-
Dietrich D, Kneip C, Raji O, et al. Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates. Int J Oncol 2012;40:825-32
-
(2012)
Int J Oncol
, vol.40
, pp. 825-832
-
-
Dietrich, D.1
Kneip, C.2
Raji, O.3
-
110
-
-
80052967970
-
SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma
-
Kneip C, Schmidt B, Seegebarth A, et al. SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma. J Thorac Oncol 2011;6:1632-8
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1632-1638
-
-
Kneip, C.1
Schmidt, B.2
Seegebarth, A.3
-
111
-
-
84888119068
-
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
-
Chan KC, Jiang P, Chan CW, et al. Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing. Proc Natl Acad Sci USA 2013;110:18761-8
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 18761-18768
-
-
Chan, K.C.1
Jiang, P.2
Chan, C.W.3
-
112
-
-
84894025759
-
Clinical significance of heterogeneity in response to retreatment with epidermal growth factor receptor tyrosine kinase inhibitors in patients with lung cancer acquiring secondary resistance to the drug
-
Lee Y, Kim HY, Lee SH, et al. Clinical significance of heterogeneity in response to retreatment with epidermal growth factor receptor tyrosine kinase inhibitors in patients with lung cancer acquiring secondary resistance to the drug. Clin Lung Cancer 2014;15:145-51
-
(2014)
Clin Lung Cancer
, vol.15
, pp. 145-151
-
-
Lee, Y.1
Kim, H.Y.2
Lee, S.H.3
-
113
-
-
84873887494
-
Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer
-
Bai H, Wang Z, Wang Y, et al. Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer. PLoS One 2013;8:e54170
-
(2013)
PLoS One
, vol.8
, pp. e54170
-
-
Bai, H.1
Wang, Z.2
Wang, Y.3
-
114
-
-
57349141411
-
EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance
-
Jiang SX, Yamashita K, Yamamoto M, et al. EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance. Int J Cancer 2008;123: 2480-6
-
(2008)
Int J Cancer
, vol.123
, pp. 2480-2486
-
-
Jiang, S.X.1
Yamashita, K.2
Yamamoto, M.3
-
115
-
-
84887556493
-
Lung cancer biomarkers present status and future developments
-
Cagle PT, Allen TC, Olsen RJ. Lung cancer biomarkers present status and future developments. Arch Pathol Lab Med 2013;137:1191-8
-
(2013)
Arch Pathol Lab Med
, vol.137
, pp. 1191-1198
-
-
Cagle, P.T.1
Allen, T.C.2
Olsen, R.J.3
-
116
-
-
84887529187
-
Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma
-
Cai G, Wong R, Chhieng D, et al. Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma. Cancer Cytopathol 2013;121:500-7
-
(2013)
Cancer Cytopathol
, vol.121
, pp. 500-507
-
-
Cai, G.1
Wong, R.2
Chhieng, D.3
-
118
-
-
79955820904
-
Benchmarking of mutation diagnostics in clinical lung cancer specimens
-
Querings S, Altmüller J, Ansen S, et al. Benchmarking of mutation diagnostics in clinical lung cancer specimens. PLoS One 2011;6:e19601
-
(2011)
PLoS One
, vol.6
, pp. e19601
-
-
Querings, S.1
Altmüller, J.2
Ansen, S.3
-
119
-
-
84890936831
-
Biopsy and mutation detection strategies in non-small cell lung cancer
-
Jung CY. Biopsy and mutation detection strategies in non-small cell lung cancer. Tuberc Respir Dis 2013;75:181-7
-
(2013)
Tuberc Respir Dis
, vol.75
, pp. 181-187
-
-
Jung, C.Y.1
-
120
-
-
77649091118
-
A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
-
Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res 2010;16:1561-71
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1561-1571
-
-
Mino-Kenudson, M.1
Chirieac, L.R.2
Law, K.3
-
121
-
-
84874023763
-
Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas
-
Sholl LM, Weremowicz S, Gray SW, et al. Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas. J Thorac Oncol 2013;8: 322-8
-
(2013)
J Thorac Oncol
, vol.8
, pp. 322-328
-
-
Sholl, L.M.1
Weremowicz, S.2
Gray, S.W.3
-
122
-
-
84937700941
-
Comparison of methods in the detection of ALK and ROS1 rearrangements in lung cancer
-
Rogers TM, Russell PA, Wright G, et al. Comparison of methods in the detection of ALK and ROS1 rearrangements in lung cancer. J Thorac Oncol 2015;10:611-18
-
(2015)
J Thorac Oncol
, vol.10
, pp. 611-618
-
-
Rogers, T.M.1
Russell, P.A.2
Wright, G.3
-
123
-
-
84925745314
-
Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria
-
Von Laffert M, Warth A, Penzel R, et al. Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria. J Thorac Oncol 2014;9:1685-92
-
(2014)
J Thorac Oncol
, vol.9
, pp. 1685-1692
-
-
Von Laffert, M.1
Warth, A.2
Penzel, R.3
-
124
-
-
84937679845
-
ALK FISH rearranged and amplified tumor with negative immunohistochemistry: A rare and challenging case concerning ALK status screening in lung cancer
-
[Epub ahead of print]
-
Uguen A, Talagas M, Andrieu-Key S, et al. ALK FISH rearranged and amplified tumor with negative immunohistochemistry: a rare and challenging case concerning ALK status screening in lung cancer. Ann Oncol 2015. [Epub ahead of print]
-
(2015)
Ann Oncol
-
-
Uguen, A.1
Talagas, M.2
Andrieu-Key, S.3
-
125
-
-
84922540993
-
Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK 'borderline'-positive rearrangements or a high copy number: A potential major issue for anti-ALK therapeutic strategies
-
Llie Ml, Bence C, Hofman V, et al. Discrepancies between FISH and immunohistochemistry for assessment of the ALK status are associated with ALK 'borderline'-positive rearrangements or a high copy number: a potential major issue for anti-ALK therapeutic strategies. Ann Oncol 2015;26:238-44
-
(2015)
Ann Oncol
, vol.26
, pp. 238-244
-
-
Llie, M.L.1
Bence, C.2
Hofman, V.3
-
126
-
-
84898058460
-
Epidermal growth factor receptor mutation-specific immunohistochemical antibodies in lung adenocarcinoma
-
Allo G, Bandarchi B, Yanagawa N, et al. Epidermal growth factor receptor mutation-specific immunohistochemical antibodies in lung adenocarcinoma. Histopathology 2014;64:826-39
-
(2014)
Histopathology
, vol.64
, pp. 826-839
-
-
Allo, G.1
Bandarchi, B.2
Yanagawa, N.3
-
127
-
-
84883863776
-
Immunohistochemical staining with EGFR mutation-specific antibodies: High specificity as a diagnostic marker for lung adenocarcinoma
-
Wen YH, Brogi E, Hasanovic A, et al. Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma. Mod Pathol 2013;26: 1197-203
-
(2013)
Mod Pathol
, vol.26
, pp. 1197-1203
-
-
Wen, Y.H.1
Brogi, E.2
Hasanovic, A.3
-
128
-
-
84904384871
-
ROS1 expression and translocations in non-small-cell lung cancer: Clinicopathological analysis of 1478 cases
-
Warth A, Muley T, Dienemann H, et al. ROS1 expression and translocations in non-small-cell lung cancer: clinicopathological analysis of 1478 cases. Histopathology 2014;65:187-94
-
(2014)
Histopathology
, vol.65
, pp. 187-194
-
-
Warth, A.1
Muley, T.2
Dienemann, H.3
-
129
-
-
84899989532
-
Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers
-
Yoshida A, Tsuta K, Wakai S, et al. Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers. Mod Pathol 2014;27: 711-20
-
(2014)
Mod Pathol
, vol.27
, pp. 711-720
-
-
Yoshida, A.1
Tsuta, K.2
Wakai, S.3
-
130
-
-
84874835176
-
Ascertaining an appropriate diagnostic algorithm using EGFR mutation-specific antibodies to detect EGFR status in non-small-cell lung cancer
-
Jiang G, Fan C, Zhang X, et al. Ascertaining an appropriate diagnostic algorithm using EGFR mutation-specific antibodies to detect EGFR status in non-small-cell lung cancer. PLoS One 2013;8:e59183
-
(2013)
PLoS One
, vol.8
, pp. e59183
-
-
Jiang, G.1
Fan, C.2
Zhang, X.3
-
131
-
-
55549089660
-
Accurate whole human genome sequencing using reversible terminator chemistry
-
Bentley DR, Balasubramanian S, Swerdlow HP, et al. Accurate whole human genome sequencing using reversible terminator chemistry. Nature 2008;456:53-9
-
(2008)
Nature
, vol.456
, pp. 53-59
-
-
Bentley, D.R.1
Balasubramanian, S.2
Swerdlow, H.P.3
-
132
-
-
84874575400
-
From targets to targeted therapies and molecular profiling in non-small cell lung carcinoma
-
Thomas A, Rajan A, Lopez-Chavez A, et al. From targets to targeted therapies and molecular profiling in non-small cell lung carcinoma. Ann Oncol 2013;24:577-85
-
(2013)
Ann Oncol
, vol.24
, pp. 577-585
-
-
Thomas, A.1
Rajan, A.2
Lopez-Chavez, A.3
-
133
-
-
84898763401
-
Present and future molecular testing of lung carcinoma
-
Dacic S, Nikiforova MN. Present and future molecular testing of lung carcinoma. Adv Anat Pathol 2014;21:94-9
-
(2014)
Adv Anat Pathol
, vol.21
, pp. 94-99
-
-
Dacic, S.1
Nikiforova, M.N.2
-
134
-
-
70449106047
-
Enabling technologies of genomic-scale sequence enrichment for targeted high-throughput sequencing
-
Summerer D. Enabling technologies of genomic-scale sequence enrichment for targeted high-throughput sequencing. Genomics 2009;94:363-8
-
(2009)
Genomics
, vol.94
, pp. 363-368
-
-
Summerer, D.1
-
135
-
-
84890295992
-
The evolving genomic classification of lung cancer
-
Shames DS, Wistuba II. The evolving genomic classification of lung cancer. J Pathol 2014;232:121-33
-
(2014)
J Pathol
, vol.232
, pp. 121-133
-
-
Shames, D.S.1
Wistuba, I.I.2
-
137
-
-
84866410479
-
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
-
Imielinski M, Berger AH, Hammerman PS, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012;150:1107-20
-
(2012)
Cell
, vol.150
, pp. 1107-1120
-
-
Imielinski, M.1
Berger, A.H.2
Hammerman, P.S.3
-
138
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012;489:519-25
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
Cancer Genome Atlas Research Network1
-
139
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature 2014;511:543-50
-
(2014)
Nature
, vol.511
, pp. 543-550
-
-
Cancer Genome Atlas Research Network1
-
140
-
-
0019945899
-
Demonstration of the stem cell nature of clonogenic tumor cells from lung cancer patients
-
Carney DN, Gazdar AF, Bunn PA Jr, et al. Demonstration of the stem cell nature of clonogenic tumor cells from lung cancer patients. Stem Cells 1982;1:149-64
-
(1982)
Stem Cells
, vol.1
, pp. 149-164
-
-
Carney, D.N.1
Gazdar, A.F.2
Bunn, P.A.3
-
141
-
-
84861737097
-
Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy
-
Shien K, Toyooka S, Ichimura K, et al. Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy. Lung Cancer 2012;77: 162-7
-
(2012)
Lung Cancer
, vol.77
, pp. 162-167
-
-
Shien, K.1
Toyooka, S.2
Ichimura, K.3
-
142
-
-
84879341208
-
Cancer stem cells in lung cancer: Evidence and controversies
-
Alamgeer M, Peacock CD, Matsui W, et al. Cancer stem cells in lung cancer: evidence and controversies. Respirology 2013;18: 757-64
-
(2013)
Respirology
, vol.18
, pp. 757-764
-
-
Alamgeer, M.1
Peacock, C.D.2
Matsui, W.3
-
143
-
-
84867385274
-
Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer
-
Gottschling S, Schnabel PA, Herth FJ, et al. Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer. Cancer Genomics Proteomics 2012;9:275-86
-
(2012)
Cancer Genomics Proteomics
, vol.9
, pp. 275-286
-
-
Gottschling, S.1
Schnabel, P.A.2
Herth, F.J.3
-
144
-
-
84897047034
-
Cancer stem cell-related marker expression in lung adenocarcinoma and relevance of histologic subtypes based on IASLC/ATS/ERS classification
-
Shimada Y, Saji H, Nomura M, et al. Cancer stem cell-related marker expression in lung adenocarcinoma and relevance of histologic subtypes based on IASLC/ATS/ERS classification. Onco Targets Ther 2013;6:1597-604
-
(2013)
Onco Targets Ther
, vol.6
, pp. 1597-1604
-
-
Shimada, Y.1
Saji, H.2
Nomura, M.3
-
145
-
-
84937695885
-
Molecular epidemiology of lung cancer and geographic variations with special reference to EGFR mutations
-
Tetsuya M. Molecular epidemiology of lung cancer and geographic variations with special reference to EGFR mutations. Transl Lung Cancer Res 2014;3:205-11
-
(2014)
Transl Lung Cancer Res
, vol.3
, pp. 205-211
-
-
Tetsuya, M.1
-
146
-
-
24344459713
-
Epidermal growth factor receptor activating mutations in Spanish gefitinib-treated non-small-cell lung cancer patients
-
Cortes-Funes H, Gomez C, Rosell R, et al. Epidermal growth factor receptor activating mutations in Spanish gefitinib-treated non-small-cell lung cancer patients. Ann Oncol 2005;16:1081-6
-
(2005)
Ann Oncol
, vol.16
, pp. 1081-1086
-
-
Cortes-Funes, H.1
Gomez, C.2
Rosell, R.3
-
147
-
-
84881664448
-
Frequency of EGFR and KRAS mutations in patients with non-small cell lung cancer by racial background: Do disparities exist?
-
Bauml J, Mick R, Zhang Y, et al. Frequency of EGFR and KRAS mutations in patients with non-small cell lung cancer by racial background: do disparities exist? Lung Cancer 2013;81:347-53
-
(2013)
Lung Cancer
, vol.81
, pp. 347-353
-
-
Bauml, J.1
Mick, R.2
Zhang, Y.3
-
148
-
-
84862779691
-
High incidence of EGFR mutations in Korean men smokers with no intratumoral heterogeneity of lung adenocarcinomas: Correlation with histologic subtypes, EGFR/TTF-1 expressions, and clinical features
-
Sun PL, Seol H, Lee HJ, et al. High incidence of EGFR mutations in Korean men smokers with no intratumoral heterogeneity of lung adenocarcinomas: correlation with histologic subtypes, EGFR/TTF-1 expressions, and clinical features. J Thorac Oncol 2012;7:323-30
-
(2012)
J Thorac Oncol
, vol.7
, pp. 323-330
-
-
Sun, P.L.1
Seol, H.2
Lee, H.J.3
-
149
-
-
79960860845
-
Screening for EGFR mutations in lung cancer, a report from India
-
Sahoo R, Harini VV, Babu VC, et al. Screening for EGFR mutations in lung cancer, a report from India. Lung Cancer 2011;73:316-19
-
(2011)
Lung Cancer
, vol.73
, pp. 316-319
-
-
Sahoo, R.1
Harini, V.V.2
Babu, V.C.3
-
150
-
-
84938287765
-
Updated Frequency of EGFR and KRAS Mutations in NonSmall-Cell Lung Cancer in Latin America: The Latin-American Consortium for the Investigation of Lung Cancer (CLICaP)
-
Arrieta O, Cardona AF, Martn C, et al. Updated Frequency of EGFR and KRAS Mutations in NonSmall-Cell Lung Cancer in Latin America: The Latin-American Consortium for the Investigation of Lung Cancer (CLICaP). J Thorac Oncol 2015;10: 838-43
-
(2015)
J Thorac Oncol
, vol.10
, pp. 838-843
-
-
Arrieta, O.1
Cardona, A.F.2
Martn, C.3
-
151
-
-
77955092315
-
PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers
-
Jin G, Kim MJ, Jeon HS, et al. PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers. Lung Cancer 2010;69:279-83
-
(2010)
Lung Cancer
, vol.69
, pp. 279-283
-
-
Jin, G.1
Kim, M.J.2
Jeon, H.S.3
-
152
-
-
84892859492
-
KRAS mutations in non-small-cell lung cancer and colorectal cancer: Implications for EGFR-targeted therapies
-
Maus MK, Grimminger PP, Mack PC, et al. KRAS mutations in non-small-cell lung cancer and colorectal cancer: implications for EGFR-targeted therapies. Lung Cancer 2014;83:163-7
-
(2014)
Lung Cancer
, vol.83
, pp. 163-167
-
-
Maus, M.K.1
Grimminger, P.P.2
Mack, P.C.3
-
153
-
-
84871040678
-
Favorable clinical outcomes of pemetrexed treatment in anaplastic lymphoma kinase positive non-small-cell lung cancer
-
Lee HY, Ahn HK, Jeong JY, et al. Favorable clinical outcomes of pemetrexed treatment in anaplastic lymphoma kinase positive non-small-cell lung cancer. Lung Cancer 2013;79:40-5
-
(2013)
Lung Cancer
, vol.79
, pp. 40-45
-
-
Lee, H.Y.1
Ahn, H.K.2
Jeong, J.Y.3
-
154
-
-
84892512436
-
Fibroblast growth factor receptor 1 amplification in non-small cell lung cancer by quantitative real-time PCR
-
Gadgeel SM, Chen W, Cote ML, et al. Fibroblast growth factor receptor 1 amplification in non-small cell lung cancer by quantitative real-time PCR. PLoS One 2013;8:e79820
-
(2013)
PLoS One
, vol.8
, pp. e79820
-
-
Gadgeel, S.M.1
Chen, W.2
Cote, M.L.3
-
155
-
-
84881667061
-
Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell
-
Tran TN, Selinger CI, Kohonen-Corish MR, et al. Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell. Lung Cancer. Lung Cancer 2013;81:462-7
-
(2013)
Lung Cancer. Lung Cancer
, vol.81
, pp. 462-467
-
-
Tran, T.N.1
Selinger, C.I.2
Kohonen-Corish, M.R.3
-
156
-
-
84895788351
-
PIK3CA mutations frequently coexist with EGFR/kras mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup
-
Wang L, Hu H, Pan Y, et al. PIK3CA Mutations Frequently Coexist with EGFR/KRAS Mutations in Non-Small Cell Lung Cancer and Suggest Poor Prognosis in EGFR/KRAS Wildtype Subgroup. PLoS One 2014;9:e88291
-
(2014)
PLoS One
, vol.9
, pp. e88291
-
-
Wang, L.1
Hu, H.2
Pan, Y.3
-
157
-
-
80052558779
-
Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers
-
Tomizawa K, Suda K, Onozato R, et al. Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers. Lung Cancer 2011;74:139-44
-
(2011)
Lung Cancer
, vol.74
, pp. 139-144
-
-
Tomizawa, K.1
Suda, K.2
Onozato, R.3
-
158
-
-
84863338079
-
ROS1 rearrangements define a unique molecular class of lung cancer
-
Bergethon K, Shaw AT, Ou SH, et al. ROS1 rearrangements define a unique molecular class of lung cancer. J Clin Oncol 2012;30:863-70
-
(2012)
J Clin Oncol
, vol.30
, pp. 863-870
-
-
Bergethon, K.1
Shaw, A.T.2
Ou, S.H.3
-
159
-
-
77951878615
-
MEK1 and AKT2 mutations in Japanese lung cancer
-
Sasaki H, Hikosaka Y, Kawano O, et al. MEK1 and AKT2 mutations in Japanese lung cancer. J Thorac Oncol 2010;5: 597-600
-
(2010)
J Thorac Oncol
, vol.5
, pp. 597-600
-
-
Sasaki, H.1
Hikosaka, Y.2
Kawano, O.3
-
160
-
-
84879810589
-
Targeting long non-coding RNAs in cancers: Progress and prospects
-
Li CH, Chen Y. Targeting long non-coding RNAs in cancers: progress and prospects. Int J Biochem Cell Biol 2013;45:1895-910
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 1895-1910
-
-
Li, C.H.1
Chen, Y.2
|