-
1
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, et al. (2004) EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 304: 1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
-
2
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non - small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, et al. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non - small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
-
3
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, Doherty J, Politi K, et al. (2004) EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 101: 13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
-
4
-
-
33947498978
-
Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
-
Sequist LV, Bell DW, Lynch TJ, Haber DA, (2007) Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 25: 587-595.
-
(2007)
J Clin Oncol
, vol.25
, pp. 587-595
-
-
Sequist, L.V.1
Bell, D.W.2
Lynch, T.J.3
Haber, D.A.4
-
5
-
-
33947434048
-
Which biomarker predicts benefit from EGFR-TKI treatment for patients with lung cancer?
-
Uramoto H, Mitsudomi T, (2007) Which biomarker predicts benefit from EGFR-TKI treatment for patients with lung cancer? Br J Cancer 96: 857-863.
-
(2007)
Br J Cancer
, vol.96
, pp. 857-863
-
-
Uramoto, H.1
Mitsudomi, T.2
-
6
-
-
84866940771
-
Personalized targeted therapy for lung cancer
-
Wu K, House L, Liu W, Cho WC, (2012) Personalized targeted therapy for lung cancer. Int J Mol Sci 13(9): 11471-11496.
-
(2012)
Int J Mol Sci
, vol.13
, Issue.9
, pp. 11471-11496
-
-
Wu, K.1
House, L.2
Liu, W.3
Cho, W.C.4
-
7
-
-
84873402328
-
Epidermal growth factor receptor mutations in female patients with postoperative recurrent non-small-cell lung cancer
-
Na II, Kim HR, Lee JK, Park SH, Kim CH, et al. (2012) Epidermal growth factor receptor mutations in female patients with postoperative recurrent non-small-cell lung cancer. J Cancer Res Ther 8(3): 373-378.
-
(2012)
J Cancer Res Ther
, vol.8
, Issue.3
, pp. 373-378
-
-
Na, I.I.1
Kim, H.R.2
Lee, J.K.3
Park, S.H.4
Kim, C.H.5
-
8
-
-
44249125258
-
Challenges of detecting EGFR T790M in gefitinib/erlotinib-resistant tumors
-
Jänne PA, (2008) Challenges of detecting EGFR T790M in gefitinib/erlotinib-resistant tumors. Lung Cancer 60: s3-9.
-
(2008)
Lung Cancer
, vol.60
-
-
Jänne, P.A.1
-
9
-
-
78349265779
-
Reciprocal and Complementary Role of MET Amplification and EGFR T790M Mutation in Acquired Resistance to Kinase Inhibitors in Lung Cancer
-
Suda K, Murakami I, Katayama T, Tomizawa K, Osada H, et al. (2010) Reciprocal and Complementary Role of MET Amplification and EGFR T790M Mutation in Acquired Resistance to Kinase Inhibitors in Lung Cancer. Clin Cancer Res 16: 5489-5498.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5489-5498
-
-
Suda, K.1
Murakami, I.2
Katayama, T.3
Tomizawa, K.4
Osada, H.5
-
10
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, et al. (2005) Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2: e73.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
-
11
-
-
46749156706
-
Engelman. Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins
-
Guix M, Faber AC, Wang SE, Olivares MG, Song Y, et al. (2008) Engelman. Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins. J Clin Invest118(7): 2609-2619.
-
(2008)
J Clin Invest
, vol.118
, Issue.7
, pp. 2609-2619
-
-
Guix, M.1
Faber, A.C.2
Wang, S.E.3
Olivares, M.G.4
Song, Y.5
-
12
-
-
84858608410
-
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
-
Magee JA, Piskounova E, Morrison SJ, (2012) Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty. Cancer Cell 21: 283-296.
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
13
-
-
84859113048
-
Genetic heterogeneity and cancer drug resistance
-
Turner NC, Reis-Filho JS, (2012) Genetic heterogeneity and cancer drug resistance. Lancet Oncol 13: e178-85.
-
(2012)
Lancet Oncol
, vol.13
-
-
Turner, N.C.1
Reis-Filho, J.S.2
-
14
-
-
0022600767
-
Mechanisms of tumor progression
-
Nowell P, (1986) Mechanisms of tumor progression. Cancer Res 46: 2203-2207.
-
(1986)
Cancer Res
, vol.46
, pp. 2203-2207
-
-
Nowell, P.1
-
15
-
-
84863393080
-
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, et al. (2012) Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. N Engl J Med 366(10): 883-892.
-
(2012)
N Engl J Med
, vol.366
, Issue.10
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
-
16
-
-
83455176258
-
Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma
-
Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, et al. (2011) Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma. Cancer Cell 20: 810-817.
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
-
17
-
-
84865442609
-
Influence of Chemotherapy on EGFR Mutation Status Among Patients With Non-Small-Cell Lung Cancer
-
Bai H, Wang ZhJ, Chen KN, Zhao J, Lee J, et al. (2012) Influence of Chemotherapy on EGFR Mutation Status Among Patients With Non-Small-Cell Lung Cancer. J Clin Oncol 30: 3077-3083.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3077-3083
-
-
Bai, H.1
Wang, Z.H.J.2
Chen, K.N.3
Zhao, J.4
Lee, J.5
-
18
-
-
80051612067
-
Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma
-
Yatabe Y, Matsuo K, Mitsudomi T, (2011) Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma. J Clin Oncol 29(22): 2972-2977.
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 2972-2977
-
-
Yatabe, Y.1
Matsuo, K.2
Mitsudomi, T.3
-
19
-
-
66849091226
-
Epidermal Growth Factor Receptor Mutations in Plasma DNA Samples Predict Tumor Response in Chinese Patients With Stages IIIB to IV Non-Small-Cell Lung Cancer
-
Bai H, Mao L, Wang HS, Zhao J, Yang L, et al. (2009) Epidermal Growth Factor Receptor Mutations in Plasma DNA Samples Predict Tumor Response in Chinese Patients With Stages IIIB to IV Non-Small-Cell Lung Cancer. J Clin Oncol 27(16): 2653-2659.
-
(2009)
J Clin Oncol
, vol.27
, Issue.16
, pp. 2653-2659
-
-
Bai, H.1
Mao, L.2
Wang, H.S.3
Zhao, J.4
Yang, L.5
-
20
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
Cappuzzo F, Hirsch FR, Rossi E, Bartolini S, Ceresoli GL, et al. (2005) Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 97: 643-655.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
Bartolini, S.4
Ceresoli, G.L.5
-
21
-
-
0035691670
-
The new World Health organization classification of lung tumours
-
Brambilla E, Travis WD, Colby TV, Corrin B, Shimosato Y, (2001) The new World Health organization classification of lung tumours. Eur Respir J 18: 1059-1068.
-
(2001)
Eur Respir J
, vol.18
, pp. 1059-1068
-
-
Brambilla, E.1
Travis, W.D.2
Colby, T.V.3
Corrin, B.4
Shimosato, Y.5
-
23
-
-
84874606355
-
EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples
-
[Epub ahead of print]
-
Ellison G, Zhu G, Moulis A, Dearden S, Speake G, et al. (2012) EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples. J Clin Pathol Nov 21. [Epub ahead of print].
-
(2012)
J Clin Pathol Nov 21
-
-
Ellison, G.1
Zhu, G.2
Moulis, A.3
Dearden, S.4
Speake, G.5
-
24
-
-
33845572242
-
Evaluation of Denaturing High-Performance Liquid Chromatography as a Rapid Detection Method for Identification of Epidermal Growth Factor Receptor mutations in Non-small-Cell Lung Cancer
-
Cohen V, Agulnik JS, Jarry J, Batist G, Small D, et al. (2006) Evaluation of Denaturing High-Performance Liquid Chromatography as a Rapid Detection Method for Identification of Epidermal Growth Factor Receptor mutations in Non-small-Cell Lung Cancer. Cancer 107: 2858-2865.
-
(2006)
Cancer
, vol.107
, pp. 2858-2865
-
-
Cohen, V.1
Agulnik, J.S.2
Jarry, J.3
Batist, G.4
Small, D.5
-
25
-
-
33845989517
-
Detection of Epidermal Growth Factor Receptor Variations by Partially Denaturing HPLC
-
Chin TM, Anuar D, Soo R, Salto-Tellez M, Li WQ, et al. (2007) Detection of Epidermal Growth Factor Receptor Variations by Partially Denaturing HPLC. Clin Chemistry53(1): 62-70.
-
(2007)
Clin Chemistry
, vol.53
, Issue.1
, pp. 62-70
-
-
Chin, T.M.1
Anuar, D.2
Soo, R.3
Salto-Tellez, M.4
Li, W.Q.5
-
26
-
-
33846218549
-
Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas
-
Pühringer-Oppermann FA, Stein HJ, Sarbia M, (2007) Lack of EGFR gene mutations in exons 19 and 21 in esophageal (Barrett's) adenocarcinomas. Dis Esophagus 20: 9-11.
-
(2007)
Dis Esophagus
, vol.20
, pp. 9-11
-
-
Pühringer-Oppermann, F.A.1
Stein, H.J.2
Sarbia, M.3
-
27
-
-
0036792092
-
Metapopulation dynamics and spatial heterogeneity in cancer
-
Gonzalez-Garcia I, Sole RV, Costa J, (2002) Metapopulation dynamics and spatial heterogeneity in cancer. Proc Natl Acad Sci USA 99: 13085-13089.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13085-13089
-
-
Gonzalez-Garcia, I.1
Sole, R.V.2
Costa, J.3
-
28
-
-
0343619372
-
Genetic heterogeneity in ductal carcinoma of the breast
-
Lichy JH, Dalbègue F, Zavar M, Washington C, Tsai MM, et al. (2000) Genetic heterogeneity in ductal carcinoma of the breast. Lab Invest 80: 291-301.
-
(2000)
Lab Invest
, vol.80
, pp. 291-301
-
-
Lichy, J.H.1
Dalbègue, F.2
Zavar, M.3
Washington, C.4
Tsai, M.M.5
-
29
-
-
0034122741
-
Molecular evolution and intratumor heterogeneity by topographic compartments in muscle-invasive transitional cell carcinoma of the urinary bladder
-
Diaz-Cano SJ, Blanes A, Rubio J, Matilla A, Wolfe HJ, (2000) Molecular evolution and intratumor heterogeneity by topographic compartments in muscle-invasive transitional cell carcinoma of the urinary bladder. Lab Invest 80: 279-289.
-
(2000)
Lab Invest
, vol.80
, pp. 279-289
-
-
Diaz-Cano, S.J.1
Blanes, A.2
Rubio, J.3
Matilla, A.4
Wolfe, H.J.5
-
30
-
-
0032481322
-
Evidence of independent origin of multiple tumors from patients with prostate cancer
-
Cheng L, Song SY, Pretlow TG, Abdul-Karim FW, Kung HJ, et al. (1998) Evidence of independent origin of multiple tumors from patients with prostate cancer. J Natl Cancer Inst 90: 233-237.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 233-237
-
-
Cheng, L.1
Song, S.Y.2
Pretlow, T.G.3
Abdul-Karim, F.W.4
Kung, H.J.5
-
31
-
-
43649099401
-
Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib
-
Taniguchi K, Okami J, Kodama K, Higashiyama M, Kato K, (2008) Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib. Cancer Sci 99(5): 929-935.
-
(2008)
Cancer Sci
, vol.99
, Issue.5
, pp. 929-935
-
-
Taniguchi, K.1
Okami, J.2
Kodama, K.3
Higashiyama, M.4
Kato, K.5
|