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Volumn 81, Issue 3, 2013, Pages 347-353

Frequency of EGFR and KRAS mutations in patients with non small cell lung cancer by racial background: Do disparities exist?

Author keywords

EGFR; KRAS; NSCLC; Racial disparity

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN;

EID: 84881664448     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2013.05.011     Document Type: Article
Times cited : (84)

References (31)
  • 2
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
    • Zhou C., Wu Y.-L., Chen G., Feng J., Liu X.-Q., Wang C., et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011, 12(8):735-742. 10.1016/S1470-2045(11)70184-X.
    • (2011) Lancet Oncol , vol.12 , Issue.8 , pp. 735-742
    • Zhou, C.1    Wu, Y.-L.2    Chen, G.3    Feng, J.4    Liu, X.-Q.5    Wang, C.6
  • 3
    • 79960702788 scopus 로고    scopus 로고
    • Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS)
    • Fukuoka M., Wu Y.-L., Thongprasert S., Sunpaweravong P., Leong S.-S., Sriuranpong V., et al. Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS). J Clin Oncol: Offi J Am Soc Clin Oncol 2011, 29(21):2866-2874. 10.1200/JCO.2010.33.4235.
    • (2011) J Clin Oncol: Offi J Am Soc Clin Oncol , vol.29 , Issue.21 , pp. 2866-2874
    • Fukuoka, M.1    Wu, Y.-L.2    Thongprasert, S.3    Sunpaweravong, P.4    Leong, S.-S.5    Sriuranpong, V.6
  • 4
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350(21):2129-2139. 10.1056/NEJMoa040938.
    • (2004) N Engl J Med , vol.350 , Issue.21 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3    Gurubhagavatula, S.4    Okimoto, R.A.5    Brannigan, B.W.6
  • 5
    • 72449160988 scopus 로고    scopus 로고
    • A randomized phase III study of gefitinib versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung
    • doi:6B768E63-9B38-45C6-BEA3-C3BCB9556889
    • Lee J.S., Park K., Kim S.W. A randomized phase III study of gefitinib versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung. World Conference on Lung Cancer 2009, doi:6B768E63-9B38-45C6-BEA3-C3BCB9556889.
    • (2009) World Conference on Lung Cancer
    • Lee, J.S.1    Park, K.2    Kim, S.W.3
  • 6
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Maemondo M., Inoue A., Kobayashi K., Sugawara S., Oizumi S., Isobe H., et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010, 362(25):2380-2388. 10.1056/NEJMoa0909530.
    • (2010) N Engl J Med , vol.362 , Issue.25 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3    Sugawara, S.4    Oizumi, S.5    Isobe, H.6
  • 7
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
    • Mitsudomi T., Morita S., Yatabe Y., Negoro S., Okamoto I., Tsurutani J., et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010, 11(2):121-128. 10.1016/S1470-2045(09)70364-X.
    • (2010) Lancet Oncol , vol.11 , Issue.2 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3    Negoro, S.4    Okamoto, I.5    Tsurutani, J.6
  • 8
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • Rosell R., Carcereny E., Gervais R., Vergnenegre A., Massuti B., Felip E., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012, 13(3):239-246. 10.1016/S1470-2045(11)70393-X.
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3    Vergnenegre, A.4    Massuti, B.5    Felip, E.6
  • 9
    • 79957510807 scopus 로고    scopus 로고
    • Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas
    • D'Angelo S.P., Pietanza M.C., Johnson M.L., Riely G.J., Miller V.A., Sima C.S., et al. Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas. J Clin Oncol: Offi J Am Soc Clin Oncol 2011, 29(15):2066-2070. 10.1200/JCO.2010.32.6181.
    • (2011) J Clin Oncol: Offi J Am Soc Clin Oncol , vol.29 , Issue.15 , pp. 2066-2070
    • D'Angelo, S.P.1    Pietanza, M.C.2    Johnson, M.L.3    Riely, G.J.4    Miller, V.A.5    Sima, C.S.6
  • 10
    • 33646576196 scopus 로고    scopus 로고
    • Ethnic differences in response to epidermal growth factor receptor tyrosine kinase inhibitors
    • Calvo E., Baselga J. Ethnic differences in response to epidermal growth factor receptor tyrosine kinase inhibitors. J Clin Oncol: Offi J Am Soc Clin Oncol 2006, 24(14):2158-2163. 10.1200/JCO.2006.06.5961.
    • (2006) J Clin Oncol: Offi J Am Soc Clin Oncol , vol.24 , Issue.14 , pp. 2158-2163
    • Calvo, E.1    Baselga, J.2
  • 11
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W., Miller V., Zakowski M., Doherty J., Politi K., Sarkaria I., et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004, 101(36):13306-13311. 10.1073/pnas.0405220101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.36 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3    Doherty, J.4    Politi, K.5    Sarkaria, I.6
  • 12
    • 20044364933 scopus 로고    scopus 로고
    • EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
    • Marchetti A., Martella C., Felicioni L., Barassi F., Salvatore S., Chella A., et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol: Offi J Am Soc Clin Oncol 2005, 23(4):857-865. 10.1200/JCO.2005.08.043.
    • (2005) J Clin Oncol: Offi J Am Soc Clin Oncol , vol.23 , Issue.4 , pp. 857-865
    • Marchetti, A.1    Martella, C.2    Felicioni, L.3    Barassi, F.4    Salvatore, S.5    Chella, A.6
  • 13
    • 84856568240 scopus 로고    scopus 로고
    • Racial and regional disparities in lung cancer incidence
    • Underwood J.M., Townsend J.S., Tai E., Davis S.P., Stewart S.L., White A., et al. Racial and regional disparities in lung cancer incidence. Cancer 2012, 118(7):1910-1918. 10.1002/cncr.26479.
    • (2012) Cancer , vol.118 , Issue.7 , pp. 1910-1918
    • Underwood, J.M.1    Townsend, J.S.2    Tai, E.3    Davis, S.P.4    Stewart, S.L.5    White, A.6
  • 14
    • 34249333415 scopus 로고    scopus 로고
    • Racial disparities in lung cancer
    • Berger M., Lund M.J., Brawley O.W. Racial disparities in lung cancer. Curr Probl Cancer 2007, 31(3):202-210. 10.1016/j.currproblcancer.2007.02.002.
    • (2007) Curr Probl Cancer , vol.31 , Issue.3 , pp. 202-210
    • Berger, M.1    Lund, M.J.2    Brawley, O.W.3
  • 15
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: development and validation
    • doi:EBD7B5DE-6D4F-49BD-836D-C55E8103B0D8
    • Charlson M.E., Pompei P., Ales K.L., MacKenzie C.R. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987, 40(5):373-383. doi:EBD7B5DE-6D4F-49BD-836D-C55E8103B0D8.
    • (1987) J Chronic Dis , vol.40 , Issue.5 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.L.3    MacKenzie, C.R.4
  • 17
    • 20144387591 scopus 로고    scopus 로고
    • Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer
    • Yang S.H., Mechanic L.E., Yang P., Landi M.T., Bowman E.D., Wampfler J., et al. Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer. Clin Cancer Res: Offi J Am Assoc Cancer Res 2005, 11(6):2106-2110. 10.1158/1078-0432.CCR-04-1853.
    • (2005) Clin Cancer Res: Offi J Am Assoc Cancer Res , vol.11 , Issue.6 , pp. 2106-2110
    • Yang, S.H.1    Mechanic, L.E.2    Yang, P.3    Landi, M.T.4    Bowman, E.D.5    Wampfler, J.6
  • 18
    • 73949154122 scopus 로고    scopus 로고
    • Genetic abnormalities of the EGFR pathway in African American patients with non-small-cell lung cancer
    • Leidner R.S., Fu P., Clifford B., Hamdan A., Jin C., Eisenberg R., et al. Genetic abnormalities of the EGFR pathway in African American patients with non-small-cell lung cancer. J Clin Oncol: Offi J Am Soc Clin Oncol 2009, 27(33):5620-5626. 10.1200/JCO.2009.23.1431.
    • (2009) J Clin Oncol: Offi J Am Soc Clin Oncol , vol.27 , Issue.33 , pp. 5620-5626
    • Leidner, R.S.1    Fu, P.2    Clifford, B.3    Hamdan, A.4    Jin, C.5    Eisenberg, R.6
  • 19
    • 32944481596 scopus 로고    scopus 로고
    • Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
    • Riely G.J., Pao W., Pham D., Li A.R., Rizvi N., Venkatraman E.S., et al. Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib. Clin Cancer Res: Offi J Am Assoc Cancer Res 2006, 12(3 Pt 1):839-844. 10.1158/1078-0432.CCR-05-1846.
    • (2006) Clin Cancer Res: Offi J Am Assoc Cancer Res , vol.12 , Issue.3 PART 1 , pp. 839-844
    • Riely, G.J.1    Pao, W.2    Pham, D.3    Li, A.R.4    Rizvi, N.5    Venkatraman, E.S.6
  • 21
    • 78651087933 scopus 로고    scopus 로고
    • Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans
    • PubMed PMID: 21107288; PubMed Central PMCID: PMC3337520
    • Reinersman J.M., Johnson M.L., Riely G.J., Chitale D.A., Nicastri A.D., Soff G.A., et al. Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans. J Thorac Oncol 2011, 6(1):28-31. PubMed PMID: 21107288; PubMed Central PMCID: PMC3337520. 10.1097/JTO.0b013e3181fb4fe2.
    • (2011) J Thorac Oncol , vol.6 , Issue.1 , pp. 28-31
    • Reinersman, J.M.1    Johnson, M.L.2    Riely, G.J.3    Chitale, D.A.4    Nicastri, A.D.5    Soff, G.A.6
  • 22
    • 33846444010 scopus 로고    scopus 로고
    • Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing
    • doi:7112082D-247A-474B-A8D4-86C0B9E6C204
    • Sequist L.V., Joshi V.A., Jänne P.A., Muzikansky A., Fidias P., Meyerson M., et al. Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. Oncologist 2007, 12(1):90-98. doi:7112082D-247A-474B-A8D4-86C0B9E6C204.
    • (2007) Oncologist , vol.12 , Issue.1 , pp. 90-98
    • Sequist, L.V.1    Joshi, V.A.2    Jänne, P.A.3    Muzikansky, A.4    Fidias, P.5    Meyerson, M.6
  • 23
    • 19944433797 scopus 로고    scopus 로고
    • The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers
    • doi:F6D01F68-5DAC-4BD9-BA36-8C0530A5159B
    • Tokumo M., Toyooka S., Kiura K., Shigematsu H., Tomii K., Aoe M., et al. The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers. Clin Cancer Res: Offi J Am Assoc Cancer Res 2005, 11(3):1167-1173. doi:F6D01F68-5DAC-4BD9-BA36-8C0530A5159B.
    • (2005) Clin Cancer Res: Offi J Am Assoc Cancer Res , vol.11 , Issue.3 , pp. 1167-1173
    • Tokumo, M.1    Toyooka, S.2    Kiura, K.3    Shigematsu, H.4    Tomii, K.5    Aoe, M.6
  • 24
    • 79954574430 scopus 로고    scopus 로고
    • Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry
    • Harada T., Lopez-Chavez A., Xi L., Raffeld M., Wang Y., Giaccone G. Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry. Oncogene 2011, 30(15):1744-1752. 10.1038/onc.2010.545.
    • (2011) Oncogene , vol.30 , Issue.15 , pp. 1744-1752
    • Harada, T.1    Lopez-Chavez, A.2    Xi, L.3    Raffeld, M.4    Wang, Y.5    Giaccone, G.6
  • 26
    • 0033485503 scopus 로고    scopus 로고
    • Implications and prognostic value of K-ras mutation for early-stage lung cancer in women
    • doi:D6404CFC-0A9F-4954-A516-9D0DED69CAE8
    • Nelson H.H., Christiani D.C., Mark E.J., Wiencke J.K., Wain J.C., Kelsey K.T. Implications and prognostic value of K-ras mutation for early-stage lung cancer in women. J Natl Cancer Inst 1999, 91(23):2032-2038. doi:D6404CFC-0A9F-4954-A516-9D0DED69CAE8.
    • (1999) J Natl Cancer Inst , vol.91 , Issue.23 , pp. 2032-2038
    • Nelson, H.H.1    Christiani, D.C.2    Mark, E.J.3    Wiencke, J.K.4    Wain, J.C.5    Kelsey, K.T.6
  • 27
    • 84863980235 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients
    • doi:F04AA1B0-F128-493A-A47B-F45F7553371A
    • Bacchi C.E., Ciol H., Queiroga E.M., Benine L.C., Silva L.H., Ojopi E.B. Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients. Clinics (São Paulo, Brazil) 2012, 67(5):419-424. doi:F04AA1B0-F128-493A-A47B-F45F7553371A.
    • (2012) Clinics (São Paulo, Brazil) , vol.67 , Issue.5 , pp. 419-424
    • Bacchi, C.E.1    Ciol, H.2    Queiroga, E.M.3    Benine, L.C.4    Silva, L.H.5    Ojopi, E.B.6
  • 30
    • 80051612067 scopus 로고    scopus 로고
    • Heterogeneous distribution of EGFR mutations is extremely rare in lung adenocarcinoma
    • Yatabe Y., Matsuo K., Mitsudomi T. Heterogeneous distribution of EGFR mutations is extremely rare in lung adenocarcinoma. J Clin Oncol: Offi J Am Soc Clin Oncol 2011, 29(22):2972-2977. 10.1200/JCO.2010.33.3906.
    • (2011) J Clin Oncol: Offi J Am Soc Clin Oncol , vol.29 , Issue.22 , pp. 2972-2977
    • Yatabe, Y.1    Matsuo, K.2    Mitsudomi, T.3
  • 31
    • 33847323129 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in lung cancer
    • Sharma S.V., Bell D.W., Settleman J., Haber D.A. Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 2007, 7(3):169-181. 10.1038/nrc208.
    • (2007) Nat Rev Cancer , vol.7 , Issue.3 , pp. 169-181
    • Sharma, S.V.1    Bell, D.W.2    Settleman, J.3    Haber, D.A.4


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