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Volumn 8, Issue 7, 2013, Pages 883-891

Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant

Author keywords

Anaplastic lymphoma kinase; Echinoderm microtubule associated protein like 4 anaplastic lymphoma kinase; Fluorescence in situ hybridization; Fusion transcript; Immunohistochemistry; Lung adenocarcinoma

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ECHINODERM MICROTUBULE ASSOCIATED PROTEIN LIKE 4; MICROTUBULE ASSOCIATED PROTEIN; UNCLASSIFIED DRUG;

EID: 84880917013     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3182904e22     Document Type: Article
Times cited : (67)

References (38)
  • 1
    • 0028198206 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994;263:1281-1284.
    • (1994) Science , vol.263 , pp. 1281-1284
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 2
    • 0028275645 scopus 로고
    • Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3
    • Shiota M, Fujimoto J, Semba T, Satoh H, Yamamoto T, Mori S. Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene 1994;9:1567-1574.
    • (1994) Oncogene , vol.9 , pp. 1567-1574
    • Shiota, M.1    Fujimoto, J.2    Semba, T.3    Satoh, H.4    Yamamoto, T.5    Mori, S.6
  • 3
    • 54049120220 scopus 로고    scopus 로고
    • Activating mutations in ALK provide a therapeutic target in neuroblastoma
    • George RE, Sanda T, Hanna M, et al. Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature 2008;455:975-978.
    • (2008) Nature , vol.455 , pp. 975-978
    • George, R.E.1    Sanda, T.2    Hanna, M.3
  • 4
    • 54049094708 scopus 로고    scopus 로고
    • Identification of ALK as a major familial neuroblastoma predisposition gene
    • Mossé YP, Laudenslager M, Longo L, et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature 2008;455:930-935.
    • (2008) Nature , vol.455 , pp. 930-935
    • Mossé, Y.P.1    Laudenslager, M.2    Longo, L.3
  • 5
    • 12144258439 scopus 로고    scopus 로고
    • The emerging normal and disease- related roles of anaplastic lymphoma kinase
    • Pulford K, Lamant L, Espinos E, et al. The emerging normal and disease- related roles of anaplastic lymphoma kinase. Cell Mol Life Sci 2004;61:2939-2953.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2939-2953
    • Pulford, K.1    Lamant, L.2    Espinos, E.3
  • 6
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007;448:561-566.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 7
    • 57349113565 scopus 로고    scopus 로고
    • Multiplex reverse transcription- PCR screening for EML4-ALK fusion transcripts
    • Takeuchi K, Choi YL, Soda M, et al. Multiplex reverse transcription- PCR screening for EML4-ALK fusion transcripts. Clin Cancer Res 2008;14:6618-6624.
    • (2008) Clin Cancer Res , vol.14 , pp. 6618-6624
    • Takeuchi, K.1    Choi, Y.L.2    Soda, M.3
  • 8
    • 48549098388 scopus 로고    scopus 로고
    • Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
    • Choi YL, Takeuchi K, Soda M, et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res 2008;68:4971-4976.
    • (2008) Cancer Res , vol.68 , pp. 4971-4976
    • Choi, Y.L.1    Takeuchi, K.2    Soda, M.3
  • 9
    • 37549060017 scopus 로고    scopus 로고
    • EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
    • Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 2008;3:13-17.
    • (2008) J Thorac Oncol , vol.3 , pp. 13-17
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 10
    • 40149109522 scopus 로고    scopus 로고
    • EML4-ALK fusion lung cancer: A rare acquired event
    • Perner S, Wagner PL, Demichelis F, et al. EML4-ALK fusion lung cancer: a rare acquired event. Neoplasia 2008;10:298-302.
    • (2008) Neoplasia , vol.10 , pp. 298-302
    • Perner, S.1    Wagner, P.L.2    Demichelis, F.3
  • 11
    • 47649105190 scopus 로고    scopus 로고
    • EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas
    • Shinmura K, Kageyama S, Tao H, et al. EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas. Lung Cancer 2008;61:163-169.
    • (2008) Lung Cancer , vol.61 , pp. 163-169
    • Shinmura, K.1    Kageyama, S.2    Tao, H.3
  • 12
    • 59649127007 scopus 로고    scopus 로고
    • EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues
    • Martelli MP, Sozzi G, Hernandez L, et al. EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues. Am J Pathol 2009;174:661-670.
    • (2009) Am J Pathol , vol.174 , pp. 661-670
    • Martelli, M.P.1    Sozzi, G.2    Hernandez, L.3
  • 13
    • 65249095599 scopus 로고    scopus 로고
    • The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS
    • University of Hong Kong Lung Cancer Study Group
    • Wong DW, Leung EL, So KK, et al.; University of Hong Kong Lung Cancer Study Group. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer 2009;115:1723-1733.
    • (2009) Cancer , vol.115 , pp. 1723-1733
    • Wong, D.W.1    Leung, E.L.2    So, K.K.3
  • 14
    • 0344850198 scopus 로고    scopus 로고
    • TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations
    • Hernández L, Pinyol M, Hernández S, et al. TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations. Blood 1999;94:3265-3268.
    • (1999) Blood , vol.94 , pp. 3265-3268
    • Hernández, L.1    Pinyol, M.2    Hernández, S.3
  • 15
    • 63949086127 scopus 로고    scopus 로고
    • KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
    • Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res 2009;15:3143-3149.
    • (2009) Clin Cancer Res , vol.15 , pp. 3143-3149
    • Takeuchi, K.1    Choi, Y.L.2    Togashi, Y.3
  • 16
    • 84856695102 scopus 로고    scopus 로고
    • KLC1-ALK: A novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only
    • Togashi Y, Soda M, Sakata S, et al. KLC1-ALK a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only. Plos One 2012;7.
    • (2012) Plos One , vol.7
    • Togashi, Y.1    Soda, M.2    Sakata, S.3
  • 17
    • 58149382583 scopus 로고    scopus 로고
    • A mouse model for EML4-ALKpositive lung cancer
    • Soda M, Takada S, Takeuchi K, et al. A mouse model for EML4-ALKpositive lung cancer. Proc Natl Acad Sci USA 2008;105:19893-19897.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19893-19897
    • Soda, M.1    Takada, S.2    Takeuchi, K.3
  • 18
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010;363:1693-1703.
    • (2010) N Engl J Med , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 19
    • 69349083935 scopus 로고    scopus 로고
    • Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
    • Rodig SJ, Mino-Kenudson M, Dacic S, et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res 2009;15:5216-5223.
    • (2009) Clin Cancer Res , vol.15 , pp. 5216-5223
    • Rodig, S.J.1    Mino-Kenudson, M.2    Dacic, S.3
  • 20
    • 77649091118 scopus 로고    scopus 로고
    • A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
    • Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res 2010;16:1561-1571.
    • (2010) Clin Cancer Res , vol.16 , pp. 1561-1571
    • Mino-Kenudson, M.1    Chirieac, L.R.2    Law, K.3
  • 21
    • 79951769488 scopus 로고    scopus 로고
    • Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: Correlation with fluorescence in situ hybridization
    • Paik JH, Choe G, Kim H, et al. Screening of anaplastic lymphoma kinase rearrangement by immunohistochemistry in non-small cell lung cancer: correlation with fluorescence in situ hybridization. J Thorac Oncol 2011;6:466-472.
    • (2011) J Thorac Oncol , vol.6 , pp. 466-472
    • Paik, J.H.1    Choe, G.2    Kim, H.3
  • 22
    • 79951774364 scopus 로고    scopus 로고
    • Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH
    • Yi ES, Boland JM, Maleszewski JJ, et al. Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH. J Thorac Oncol 2011;6:459-465.
    • (2011) J Thorac Oncol , vol.6 , pp. 459-465
    • Yi, E.S.1    Boland, J.M.2    Maleszewski, J.J.3
  • 23
    • 79954627704 scopus 로고    scopus 로고
    • Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis
    • Kang W, Tong JH, Chan AW, et al. Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis. Clin Cancer Res 2011;17:2130-2139.
    • (2011) Clin Cancer Res , vol.17 , pp. 2130-2139
    • Kang, W.1    Tong, J.H.2    Chan, A.W.3
  • 24
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000;132:365-386.
    • (2000) Methods Mol Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 25
    • 77952989040 scopus 로고    scopus 로고
    • Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma
    • Tong JH, Ng DC, Chau SL, et al. Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma. BMC Cancer 2010;10:253.
    • (2010) BMC Cancer , vol.10 , pp. 253
    • Tong, J.H.1    Ng, D.C.2    Chau, S.L.3
  • 26
    • 15544382365 scopus 로고    scopus 로고
    • Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: A technical review with interpretive guidelines
    • Hicks DG, Tubbs RR. Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: a technical review with interpretive guidelines. Hum Pathol 2005;36:250-261.
    • (2005) Hum Pathol , vol.36 , pp. 250-261
    • Hicks, D.G.1    Tubbs, R.R.2
  • 27
    • 0034658434 scopus 로고    scopus 로고
    • Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like)
    • Touriol C, Greenland C, Lamant L, et al. Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like). Blood 2000;95:3204-3207.
    • (2000) Blood , vol.95 , pp. 3204-3207
    • Touriol, C.1    Greenland, C.2    Lamant, L.3
  • 28
    • 0034653984 scopus 로고    scopus 로고
    • Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis
    • Ma Z, Cools J, Marynen P, et al. Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis. Blood 2000;95:2144-2149.
    • (2000) Blood , vol.95 , pp. 2144-2149
    • Ma, Z.1    Cools, J.2    Marynen, P.3
  • 29
    • 18444407158 scopus 로고    scopus 로고
    • Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor
    • Cools J, Wlodarska I, Somers R, et al. Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Gene Chromo Canc 2002;34:354-362.
    • (2002) Gene Chromo Canc , vol.34 , pp. 354-362
    • Cools, J.1    Wlodarska, I.2    Somers, R.3
  • 30
    • 3843071050 scopus 로고    scopus 로고
    • Heterogeneity of genomic breakpoints in MSN-ALK translocations in anaplastic large cell lymphoma
    • Tort F, Campo E, Pohlman B, Hsi E. Heterogeneity of genomic breakpoints in MSN-ALK translocations in anaplastic large cell lymphoma. Hum Pathol 2004;35:1038-1041.
    • (2004) Hum Pathol , vol.35 , pp. 1038-1041
    • Tort, F.1    Campo, E.2    Pohlman, B.3    Hsi, E.4
  • 31
    • 34047149804 scopus 로고    scopus 로고
    • TPM3-ALK expression induces changes in cytoskeleton organisation and confers higher metastatic capacities than other ALK fusion proteins
    • Armstrong F, Lamant L, Hieblot C, Delsol G, Touriol C. TPM3-ALK expression induces changes in cytoskeleton organisation and confers higher metastatic capacities than other ALK fusion proteins. Eur J Cancer 2007;43:640-646.
    • (2007) Eur J Cancer , vol.43 , pp. 640-646
    • Armstrong, F.1    Lamant, L.2    Hieblot, C.3    Delsol, G.4    Touriol, C.5
  • 32
    • 84862776857 scopus 로고    scopus 로고
    • Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
    • Lipson D, Capelletti M, Yelensky R, et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med 2012;18:382-384.
    • (2012) Nat Med , vol.18 , pp. 382-384
    • Lipson, D.1    Capelletti, M.2    Yelensky, R.3
  • 33
    • 78349237453 scopus 로고    scopus 로고
    • Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
    • Camidge DR, Kono SA, Flacco A, et al. Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment. Clin Cancer Res 2010;16:5581-5590.
    • (2010) Clin Cancer Res , vol.16 , pp. 5581-5590
    • Camidge, D.R.1    Kono, S.A.2    Flacco, A.3
  • 34
    • 84870891665 scopus 로고    scopus 로고
    • A screening method for the ALK fusion gene in nSCLC
    • Murakami Y, Mitsudomi T, Yatabe Y. A screening method for the ALK fusion gene in nSCLC. Front Oncol 2012;2:24.
    • (2012) Front Oncol , vol.2 , pp. 24
    • Murakami, Y.1    Mitsudomi, T.2    Yatabe, Y.3
  • 35
    • 84861680382 scopus 로고    scopus 로고
    • Detection of anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer and related issues in ALK inhibitor therapy: A literature review
    • Yi ES, Chung JH, Kulig K, Kerr KM. Detection of anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer and related issues in ALK inhibitor therapy: a literature review. Mol Diagn Ther 2012;16:143-150.
    • (2012) Mol Diagn Ther , vol.16 , pp. 143-150
    • Yi, E.S.1    Chung, J.H.2    Kulig, K.3    Kerr, K.M.4
  • 36
    • 63949087355 scopus 로고    scopus 로고
    • EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset
    • Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 2009;22:508-515.
    • (2009) Mod Pathol , vol.22 , pp. 508-515
    • Inamura, K.1    Takeuchi, K.2    Togashi, Y.3
  • 37
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • Koivunen JP, Mermel C, Zejnullahu K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008;14:4275-4283.
    • (2008) Clin Cancer Res , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullahu, K.3
  • 38
    • 84865699238 scopus 로고    scopus 로고
    • Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer
    • Peled N, Palmer G, Hirsch FR, et al. Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer. J Thorac Oncol 2012;7:e14-e16.
    • (2012) J Thorac Oncol , vol.7
    • Peled, N.1    Palmer, G.2    Hirsch, F.R.3


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