-
1
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer 2004;4:361-370. (Pubitemid 38579482)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
2
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, et al. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
-
3
-
-
0030070876
-
Epidermal growth factor receptor and c-erbB-2 oncoprotein expression in female genital tract carcinosarcomas (malignant mixed mullerian tumors) Clinicopathologic study of 82 cases
-
Costa MJ, Walls J. Epidermal growth factor receptor and c-erbB-2 oncoprotein expression in female genital tract carcinosarcomas (malignant mixed mullerian tumors). Clinicopathologic study of 82 cases. Cancer 1996;77:533-542.
-
(1996)
Cancer
, vol.77
, pp. 533-542
-
-
Costa, M.J.1
Walls, J.2
-
4
-
-
0030026822
-
The expression of epidermal growth factor receptor, HER-2/Neu, p53, and Ki-67 antigen in uterine malignant mixed mesodermal tumors and adenosarcoma
-
DOI 10.1006/gyno.1996.0015
-
Swisher EM, Gown AM, Skelly M, et al. The expression of epidermal growth factor receptor, HER-2/Neu, p53, and Ki-67 antigen in uterine malignant mixed mesodermal tumors and adenosarcoma. Gynecol Oncol 1996;60:81-88. (Pubitemid 26028461)
-
(1996)
Gynecologic Oncology
, vol.60
, Issue.1
, pp. 81-88
-
-
Swisher, E.M.1
Gown, A.M.2
Skelly, M.3
Ek, M.4
Tamimi, H.K.5
Cain, J.M.6
Greer, B.E.7
Muntz, H.G.8
Goff, B.A.9
-
6
-
-
19244366949
-
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
-
Baselga J, Pfister D, Cooper MR, et al. Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 2000;18:904-914. (Pubitemid 30106623)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.4
, pp. 904-914
-
-
Baselga, J.1
Pfister, D.2
Cooper, M.R.3
Cohen, R.4
Burtness, B.5
Bos, M.6
D'Andrea, G.7
Seidman, A.8
Norton, L.9
Gunnett, K.10
Falcey, J.11
Anderson, V.12
Waksal, H.13
Mendelsohn, J.14
-
7
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
DOI 10.1200/JCO.2004.10.182
-
Saltz LB, Meropol NJ, Loehrer PJ Sr., et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004;22:1201-1208. (Pubitemid 41079832)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.7
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer Sr., P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
8
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- refractory metastatic colorectal cancer
-
DOI 10.1056/NEJMoa033025
-
Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004;351:337-345. (Pubitemid 38944402)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
9
-
-
4344646459
-
Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
-
DOI 10.1200/JCO.2004.11.057
-
Perez-Soler R, Chachoua A, Hammond LA, et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004;22:3238-3247. (Pubitemid 41103678)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.16
, pp. 3238-3247
-
-
Perez-Soler, R.1
Chachoua, A.2
Hammond, L.A.3
Rowinsky, E.K.4
Huberman, M.5
Karp, D.6
Rigas, J.7
Clark, G.M.8
Santabarbara, P.9
Bonomi, P.10
-
10
-
-
0142055937
-
Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients with Non-Small Cell Lung Cancer: A Randomized Trial
-
DOI 10.1001/jama.290.16.2149
-
Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003;290:2149-2158. (Pubitemid 37432975)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch Jr., T.J.4
Prager, D.5
Belani, C.P.6
Schiller, J.H.7
Kelly, K.8
Spiridonidis, H.9
Sandler, A.10
Albain, K.S.11
Cella, D.12
Wolf, M.K.13
Averbuch, S.D.14
Ochs, J.J.15
Kay, A.C.16
-
11
-
-
12144287534
-
United States Food and Drug Administration Drug Approval Summary: Gefitinib (ZD1839; Iressa) Tablets
-
DOI 10.1158/1078-0432.CCR-03-0564
-
Cohen MH, Williams GA, Sridhara R, et al. United States Food and Drug Administration Drug Approval summary: Gefitinib (ZD1839; Iressa) tablets. Clin Cancer Res 2004;10:1212-1218. (Pubitemid 38365209)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.4
, pp. 1212-1218
-
-
Cohen, M.H.1
Williams, G.A.2
Sridhara, R.3
Chen, G.4
McGuinn Jr., W.D.5
Morse, D.6
Abraham, S.7
Rahman, A.8
Liang, C.9
Lostritto, R.10
Baird, A.11
Pazdur, R.12
-
12
-
-
24644458654
-
FDA drug approval summary: Erlotinib (Tarceva®) tablets
-
DOI 10.1634/theoncologist.10-7-461
-
Cohen MH, Johnson JR, Chen YF, et al. FDA drug approval summary: erlotinib (Tarceva) tablets. Oncologist 2005;10:461-466. (Pubitemid 41266326)
-
(2005)
Oncologist
, vol.10
, Issue.7
, pp. 461-466
-
-
Cohen, M.H.1
Johnson, J.R.2
Chen, Y.-F.3
Sridhara, R.4
Pazdur, R.5
-
13
-
-
2342471392
-
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350: 2129-2139. (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
14
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-1500. (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
15
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
DOI 10.1073/pnas.0405220101
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004;101:13306-13311. (Pubitemid 39209661)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.36
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
Singh, B.7
Heelan, R.8
Rusch, V.9
Fulton, L.10
Mardis, E.11
Kupfer, D.12
Wilson, R.13
Kris, M.14
Varmus, H.15
-
16
-
-
79957510807
-
Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas
-
D'Angelo SP, Pietanza MC, Johnson ML, et al. Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas. J Clin Oncol 2011;29: 2066-2070.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2066-2070
-
-
D'Angelo, S.P.1
Pietanza, M.C.2
Johnson, M.L.3
-
17
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
DOI 10.1093/jnci/dji055
-
Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005;97:339-346. (Pubitemid 40425952)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.5
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
Nomura, M.4
Suzuki, M.5
Wistuba, I.I.6
Fong, K.M.7
Lee, H.8
Toyooka, S.9
Shimizu, N.10
Fujisawa, T.11
Feng, Z.12
Roth, J.A.13
Herz, J.14
Minna, J.D.15
Gazdar, A.F.16
-
18
-
-
20044364933
-
EGFR mutations in non-small-cell lung cancer: Analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
-
DOI 10.1200/JCO.2005.08.043
-
Marchetti A, Martella C, Felicioni L, et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 2005;23:857-865. (Pubitemid 46224186)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 857-865
-
-
Marchetti, A.1
Martella, C.2
Felicioni, L.3
Barassi, F.4
Salvatore, S.5
Chella, A.6
Camplese, P.P.7
Iarussi, T.8
Mucilli, F.9
Mezzetti, A.10
Cuccurullo, F.11
Sacco, R.12
Buttitta, F.13
-
19
-
-
20244388126
-
Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence
-
DOI 10.1200/JCO.2005.00.992
-
Mitsudomi T, Kosaka T, Endoh H, et al. Mutations of the epidermal growth factor receptor gene predict prolonged survival after gefitinib treatment in patients with non-small-cell lung cancer with postoperative recurrence. J Clin Oncol 2005;23:2513-2520. (Pubitemid 47050841)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.11
, pp. 2513-2520
-
-
Mitsudomi, T.1
Kosaka, T.2
Endoh, H.3
Horio, Y.4
Hida, T.5
Mori, S.6
Hatooka, S.7
Shinoda, M.8
Takahashi, T.9
Yatabe, Y.10
-
20
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
-
DOI 10.1158/0008-5472.CAN-04-2818
-
Kosaka T, Yatabe Y, Endoh H, et al. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 2004;64:8919-8923. (Pubitemid 39665498)
-
(2004)
Cancer Research
, vol.64
, Issue.24
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Kuwano, H.4
Takahashi, T.5
Mitsudomi, T.6
-
21
-
-
33947498978
-
Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
-
DOI 10.1200/JCO.2006.07.3585
-
Sequist LV, Bell DW, Lynch TJ, et al. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 2007;25:587-595. (Pubitemid 350002967)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.5
, pp. 587-595
-
-
Sequist, L.V.1
Bell, D.W.2
Lynch, T.J.3
Haber, D.A.4
-
22
-
-
79957492069
-
American Society of Clinical Oncology provisional clinical opinion: Epidermal growth factor receptor (EGFR) Mutation testing for patients with advanced nonsmall-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy
-
Keedy VL, Temin S, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: epidermal growth factor receptor (EGFR) Mutation testing for patients with advanced nonsmall-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy. J Clin Oncol 2011;29:2121-2127.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2121-2127
-
-
Keedy, V.L.1
Temin, S.2
Somerfield, M.R.3
-
23
-
-
42549089715
-
Lung adenocarcinoma: Guiding EGFR-targeted therapy and beyond
-
DOI 10.1038/modpathol.3801018, PII 3801018
-
Ladanyi M, Pao W. Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond. Mod Pathol 2008;21:S16-S22. (Pubitemid 351592769)
-
(2008)
Modern Pathology
, vol.21
, Issue.SUPPL. 2
-
-
Ladanyi, M.1
Pao, W.2
-
24
-
-
23844544647
-
Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinoma
-
Pan Q, Pao W, Ladanyi M. Rapid polymerase chain reaction-based detection of epidermal growth factor receptor gene mutations in lung adenocarcinomas. J Mol Diagn 2005;7:396-403. (Pubitemid 41149655)
-
(2005)
Journal of Molecular Diagnostics
, vol.7
, Issue.3
, pp. 396-403
-
-
Pan, Q.1
Pao, W.2
Ladanyi, M.3
-
25
-
-
65649128973
-
Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer
-
Yu J, Kane S, Wu J, et al. Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer. Clin Cancer Res 2009;15:3023-3028.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3023-3028
-
-
Yu, J.1
Kane, S.2
Wu, J.3
-
26
-
-
77649140830
-
Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR
-
Brevet M, Arcila M, Ladanyi M. Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR. J Mol Diagn 2010;12: 169-176.
-
(2010)
J Mol Diagn
, vol.12
, pp. 169-176
-
-
Brevet, M.1
Arcila, M.2
Ladanyi, M.3
-
27
-
-
84863781238
-
Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma
-
Hasanovic A, Ang D, Moreira AL, et al. Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma. Lung Cancer 2012;77:299-305.
-
(2012)
Lung Cancer
, vol.77
, pp. 299-305
-
-
Hasanovic, A.1
Ang, D.2
Moreira, A.L.3
-
28
-
-
33847147313
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
-
DOI 10.1200/JCO.2006.09.2775
-
Wolff AC, Hammond ME, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 2007;25:118-145. (Pubitemid 350003059)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.1
, pp. 118-145
-
-
Wolff, A.C.1
Hammond, M.E.H.2
Schwartz, J.N.3
Hagerty, K.L.4
Allred, D.C.5
Cote, R.J.6
Dowsett, M.7
Fitzgibbons, P.L.8
Hanna, W.M.9
Langer, A.10
McShane, L.M.11
Paik, S.12
Pegram, M.D.13
Perez, E.A.14
Press, M.F.15
Rhodes, A.16
Sturgeon, C.17
Taube, S.E.18
Tubbs, R.19
Vance, G.H.20
Van De Vijver, M.21
Wheeler, T.M.22
Hayes, D.F.23
more..
-
29
-
-
68349139723
-
An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors
-
Chitale D, Gong Y, Taylor BS, et al. An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. Oncogene 2009;28:2773-2783.
-
(2009)
Oncogene
, vol.28
, pp. 2773-2783
-
-
Chitale, D.1
Gong, Y.2
Taylor, B.S.3
-
30
-
-
33846266252
-
Prognostic markers in triple-negative breast cancer
-
DOI 10.1002/cncr.22381
-
Rakha EA, El-Sayed ME, Green AR, et al. Prognostic markers in triple-negative breast cancer. Cancer 2007; 109:25-32. (Pubitemid 46120191)
-
(2007)
Cancer
, vol.109
, Issue.1
, pp. 25-32
-
-
Rakha, E.A.1
El-Sayed, M.E.2
Green, A.R.3
Lee, A.H.S.4
Robertson, J.F.5
Ellis, I.O.6
-
31
-
-
38449091221
-
A comparative study of the quality of DNA obtained from fresh frozen and formalin-fixed decalcified paraffin-embedded bone marrow trephine biopsy specimens using two different methods
-
DOI 10.1136/jcp.2006.045294
-
Talaulikar D, Gray JX, Shadbolt B, et al. A comparative study of the quality of DNA obtained from fresh frozen and formalin-fixed decalcified paraffin-embedded bone marrow trephine biopsy specimens using two different methods. J Clin Pathol 2008;61:119-123. (Pubitemid 351158237)
-
(2008)
Journal of Clinical Pathology
, vol.61
, Issue.1
, pp. 119-123
-
-
Talaulikar, D.1
Gray, J.X.2
Shadbolt, B.3
McNiven, M.4
Dahlstrom, J.E.5
-
32
-
-
0033669657
-
Formic acid decalcification of bone marrow trephines degrades DNA: Alternative use of EDTA allows the amplification and sequencing of relatively long PCR products
-
Wickham CL, Sarsfield P, Joyner MV, et al. Formic acid decalcification of bone marrow trephines degrades DNA: alternative use of EDTA allows the amplification and sequencing of relatively long PCR products. Mol Pathol 2000;53:336.
-
(2000)
Mol Pathol
, vol.53
, pp. 336
-
-
Wickham, C.L.1
Sarsfield, P.2
Joyner, M.V.3
|