Experimental evidence shows salubrinal, an eIF2α dephosphorylation inhibitor, reduces xenotoxicant-induced cellular damage

International Journal of Molecular Sciences

Volumn 16, Issue 7, 2015, Pages 16275-16287

  Matsuoka, Masato ^a   Komoike, Yuta ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; ATF4; Cytoprotection; Drugs; EIF2 ; Environmental pollutants; ER stress; Salubrinal; Xenotoxicants

Indexed keywords

2, 3, 7, 8 TETRACHLORODIBENZO PARA DIOXIN; 7, 8 DIHYDROXYBENZO [A] PYRENE 9, 10 OXIDE; ACTIVATING TRANSCRIPTION FACTOR 4; ARSENIC; CADMIUM; CIGARETTE SMOKE; CISPLATIN; CYCLOSPORIN; CYTOPROTECTIVE AGENT; INITIATION FACTOR 2ALPHA; PARAQUAT; ROTENONE; SALUBRINAL; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; XENOBIOTIC AGENT; CINNAMIC ACID DERIVATIVE; INITIATION FACTOR 2; THIOUREA;

APOPTOSIS; ARSENIC POISONING; CELL CYCLE ARREST; CELL DAMAGE; CELL PROTECTION; DRUG INDUCED DISEASE; ENDOPLASMIC RETICULUM STRESS; INTOXICATION; KIDNEY TUBULE EPITHELIUM; NEUROTOXICITY; PARAQUAT POISONING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; REVIEW; TRANSLATION INITIATION; VASCULAR ENDOTHELIUM; ANALOGS AND DERIVATIVES; ANIMAL; CELL DEATH; DRUG EFFECTS; HUMAN; METABOLISM; PHOSPHORYLATION;

EUKARYOTA;

ANIMALS; CELL DEATH; CINNAMATES; CYTOPROTECTION; EUKARYOTIC INITIATION FACTOR-2; HUMANS; PHOSPHORYLATION; THIOUREA; XENOBIOTICS;

EID: 84937501052     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160716275     Document Type: Review

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