The role of endoplasmic reticulum stress-related unfolded protein response in the radiocontrast medium-induced renal tubular cell injury

Toxicological Sciences

Volumn 114, Issue 2, 2010, Pages 295-301

  Wu, Cheng T ^a   Sheu, Meei L ^b   Tsai, Keh S ^a   Weng, Te I ^a   Chiang, Chih K ^c,d   Liu, Shing H ^d  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Contrast medium; ER stress; Unfolded protein response

Indexed keywords

ACETYLCYSTEINE; CASPASE; CISPLATIN; CONTRAST MEDIUM; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; INITIATION FACTOR 2ALPHA; IOPROMIDE; MEGLUMINE DIATRIZOATE; PROCASPASE 12; PROTEIN KINASE R; SALUBRINAL; SMALL INTERFERING RNA; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTRAST INDUCED NEPHROPATHY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENETIC TRANSFECTION; KIDNEY TUBULE CELL; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN CLEAVAGE; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TIME;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; CELL LINE; CELL SURVIVAL; CINNAMATES; CONTRAST MEDIA; DIATRIZOATE MEGLUMINE; EIF-2 KINASE; ELONGATION FACTOR 2 KINASE; ENDOPLASMIC RETICULUM; GENE SILENCING; HEAT-SHOCK PROTEINS; KIDNEY TUBULES, PROXIMAL; MEMBRANE GLYCOPROTEINS; PHOSPHORYLATION; PROTEIN DENATURATION; PROTEIN FOLDING; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THIOUREA; UNFOLDED PROTEIN RESPONSE;

EUKARYOTA; RATTUS;

EID: 77951614322     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq006     Document Type: Article

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