STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells

FASEB Journal

Volumn 29, Issue 3, 2015, Pages 759-771

  Schmetterer, Klaus G ^a,b,c   Neunkirchner, Alina ^a,b   Wojta Stremayr, Daniela ^a,b   Leitner, Judith ^a   Steinberger, Peter ^a   Pickl, Winfried F ^a,b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b INSTITUTE FOR MICROELECTRONICS   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Regulatory T cells; Tr1 cells

Indexed keywords

CD2 ANTIGEN; CD3 ANTIBODY; CD45RA ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 7 RECEPTOR; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; CYTOTOXIN; DNA; GRANZYME;

ARTICLE; CD4+ T LYMPHOCYTE; CELL CONTACT; CELL DEATH; COCULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; EMBRYO; ENZYME RELEASE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE REACTION; MOLECULAR CLONING; PHENOTYPE; PRIMARY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; UPREGULATION; APOPTOSIS; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; CYTOTOXINS; DNA; FLOW CYTOMETRY; GRANZYMES; HEK293 CELLS; HUMANS; LYMPHOCYTE ACTIVATION; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY;

EID: 84937439689     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-257584     Document Type: Article

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