Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells

European Journal of Immunology

Volumn 41, Issue 6, 2011, Pages 1652-1662

  Magnani, Chiara F ^a   Alberigo, Giada ^a   Bacchetta, Rosa ^a   Serafini, Giorgia ^a,b   Andreani, Marco ^b   Roncarolo, Maria Grazia ^a,c   Gregori, Silvia ^a  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

Cytotoxicity; Granzyme B; Immune regulation; Type 1 regulatory T cells

Indexed keywords

CD2 ANTIGEN; GRANZYME B; HLA ANTIGEN CLASS 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PERFORIN;

ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; BONE MARROW CELL; BYSTANDER EFFECT; CD4+ T LYMPHOCYTE; CELL INTERACTION; CELL KILLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRANULATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; LYMPHOCYTE CLONE; LYMPHOCYTE DIFFERENTIATION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REGULATORY T LYMPHOCYTE 1;

ANTIGEN-PRESENTING CELLS; ANTIGENS, CD; BETA-THALASSEMIA; BYSTANDER EFFECT; CELL ADHESION; CELL COMMUNICATION; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; GRANZYMES; HLA ANTIGENS; HUMANS; INTERLEUKIN-10; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MYELOID CELLS; PERFORIN; RECEPTORS, KIR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 79957576097     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041120     Document Type: Article

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