-
1
-
-
79960141471
-
The immunology of stroke: From mechanisms to translation
-
Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nat Med. 2011;17:796-808. doi: 10.1038/nm.2399.
-
(2011)
Nat Med
, vol.17
, pp. 796-808
-
-
Iadecola, C.1
Anrather, J.2
-
2
-
-
68349160698
-
Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
-
Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I, et al. Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med. 2009;15:946-950. doi: 10.1038/nm.1999.
-
(2009)
Nat Med
, vol.15
, pp. 946-950
-
-
Shichita, T.1
Sugiyama, Y.2
Ooboshi, H.3
Sugimori, H.4
Nakagawa, R.5
Takada, I.6
-
3
-
-
84868602402
-
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke
-
Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, et al. Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood. 2012;120:3793-3802. doi: 10.1182/blood-2012-02-412726.
-
(2012)
Blood
, vol.120
, pp. 3793-3802
-
-
Gelderblom, M.1
Weymar, A.2
Bernreuther, C.3
Velden, J.4
Arunachalam, P.5
Steinbach, K.6
-
4
-
-
79952175153
-
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke
-
Liesz A, Zhou W, Mracsko E, Karcher S, Bauer H, Schwarting S, et al. Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke. Brain. 2011;134:704-720.
-
(2011)
Brain
, vol.134
, pp. 704-720
-
-
Liesz, A.1
Zhou, W.2
Mracsko, E.3
Karcher, S.4
Bauer, H.5
Schwarting, S.6
-
6
-
-
84880794823
-
Regulatory T cells in ischemic stroke: Helpful or hazardous?
-
Schäbitz WR. Regulatory T cells in ischemic stroke: helpful or hazardous? Stroke. 2013;44:e84. doi: 10.1161/STROKEAHA.113.002228.
-
(2013)
Stroke
, vol.44
, pp. e84
-
-
Schäbitz, W.R.1
-
7
-
-
84889069185
-
The paradox role of regulatory T cells in ischemic stroke
-
Xu X, Li M, Jiang Y. The paradox role of regulatory T cells in ischemic stroke. Sci World J. 2013;2013:174373. doi: 10.1155/2013/174373.
-
(2013)
Sci World J
, vol.2013
, pp. 174373
-
-
Xu, X.1
Li, M.2
Jiang, Y.3
-
8
-
-
84883166846
-
Regulatory T cell in stroke: A new paradigm for immune regulation
-
Chen S, Wu H, Klebe D, Hong Y, Zhang J, Tang J. Regulatory T cell in stroke: a new paradigm for immune regulation. Clin Dev Immunol. 2013;2013:689827. doi: 10.1155/2013/689827.
-
(2013)
Clin Dev Immunol
, vol.2013
, pp. 689827
-
-
Chen, S.1
Wu, H.2
Klebe, D.3
Hong, Y.4
Zhang, J.5
Tang, J.6
-
9
-
-
0034716925
-
Regulatory T cells: Key controllers of immunologic selftolerance
-
Sakaguchi S. Regulatory T cells: key controllers of immunologic selftolerance. Cell. 2000;101:455-458.
-
(2000)
Cell
, vol.101
, pp. 455-458
-
-
Sakaguchi, S.1
-
10
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155:1151-1164.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
11
-
-
13144261691
-
FOXP3 acts as a rheostat of the immune response
-
Ochs HD, Ziegler SF, Torgerson TR. FOXP3 acts as a rheostat of the immune response. Immunol Rev. 2005;203:156-164. doi: 10.1111/j.0105-2896.2005.00231.x.
-
(2005)
Immunol Rev
, vol.203
, pp. 156-164
-
-
Ochs, H.D.1
Ziegler, S.F.2
Torgerson, T.R.3
-
12
-
-
31644440643
-
Regulatory cells and human cancer
-
Baecher-Allan C, Anderson DE. Regulatory cells and human cancer. Semin Cancer Biol. 2006;16:98-105. doi: 10.1016/j.semcancer.2005.11.003.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 98-105
-
-
Baecher-Allan, C.1
Anderson, D.E.2
-
13
-
-
27644433355
-
Role of regulatory T cells in human diseases
-
quiz 960
-
Chatila TA. Role of regulatory T cells in human diseases. J Allergy Clin Immunol. 2005;116:949-959, quiz 960. doi: 10.1016/j.jaci.2005.08.047.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 949-959
-
-
Chatila, T.A.1
-
14
-
-
33748602643
-
Induction of transplantation tolerance via regulatory T cells
-
Battaglia M, Roncarolo MG. Induction of transplantation tolerance via regulatory T cells. Inflamm Allergy Drug Targets. 2006;5:157-165.
-
(2006)
Inflamm Allergy Drug Targets
, vol.5
, pp. 157-165
-
-
Battaglia, M.1
Roncarolo, M.G.2
-
15
-
-
33644982044
-
Regulation of immune responses by T cells
-
Jiang H, Chess L. Regulation of immune responses by T cells. N Engl J Med. 2006;354:1166-1176. doi: 10.1056/NEJMra055446.
-
(2006)
N Engl J Med
, vol.354
, pp. 1166-1176
-
-
Jiang, H.1
Chess, L.2
-
16
-
-
33746365086
-
The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells
-
Shevach EM, DiPaolo RA, Andersson J, Zhao DM, Stephens GL, Thornton AM. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev. 2006;212:60-73. doi: 10.1111/j.0105-2896.2006.00415.x.
-
(2006)
Immunol Rev
, vol.212
, pp. 60-73
-
-
Shevach, E.M.1
Dipaolo, R.A.2
Andersson, J.3
Zhao, D.M.4
Stephens, G.L.5
Thornton, A.M.6
-
17
-
-
0028597088
-
Local immune responses in the rat cerebral cortex after middle cerebral artery occlusion
-
Schroeter M, Jander S, Witte OW, Stoll G. Local immune responses in the rat cerebral cortex after middle cerebral artery occlusion. J Neuroimmunol. 1994;55:195-203.
-
(1994)
J Neuroimmunol
, vol.55
, pp. 195-203
-
-
Schroeter, M.1
Jander, S.2
Witte, O.W.3
Stoll, G.4
-
18
-
-
65549130913
-
Temporal and spatial dynamics of cerebral immune cell accumulation in stroke
-
Gelderblom M, Leypoldt F, Steinbach K, Behrens D, Choe CU, Siler DA, et al. Temporal and spatial dynamics of cerebral immune cell accumulation in stroke. Stroke. 2009;40:1849-1857. doi: 10.1161/STROKEAHA.108.534503.
-
(2009)
Stroke
, vol.40
, pp. 1849-1857
-
-
Gelderblom, M.1
Leypoldt, F.2
Steinbach, K.3
Behrens, D.4
Choe, C.U.5
Siler, D.A.6
-
19
-
-
59649123881
-
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
-
Liesz A, Suri-Payer E, Veltkamp C, Doerr H, Sommer C, Rivest S, et al. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat Med. 2009;15:192-199.
-
(2009)
Nat Med
, vol.15
, pp. 192-199
-
-
Liesz, A.1
Suri-Payer, E.2
Veltkamp, C.3
Doerr, H.4
Sommer, C.5
Rivest, S.6
-
20
-
-
84870893039
-
Postischemic brain infiltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models
-
Zhou W, Liesz A, Bauer H, Sommer C, Lahrmann B, Valous N, et al. Postischemic brain infiltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models. Brain Pathol. 2013;23:34-44. doi: 10.1111/j.1750-3639.2012.00614.x.
-
(2013)
Brain Pathol
, vol.23
, pp. 34-44
-
-
Zhou, W.1
Liesz, A.2
Bauer, H.3
Sommer, C.4
Lahrmann, B.5
Valous, N.6
-
21
-
-
84871928577
-
Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO
-
Stubbe T, Ebner F, Richter D, Engel O, Randolf Engel O, Klehmet J, et al. Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO. J Cereb Blood Flow Metab. 2013;33:37-47. doi: 10.1038/jcbfm.2012.128.
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 37-47
-
-
Stubbe, T.1
Ebner, F.2
Richter, D.3
Engel, O.4
Randolf Engel, O.5
Klehmet, J.6
-
22
-
-
84886702007
-
Boosting regulatory T cells limits neuroinflammation in permanent cortical stroke
-
Liesz A, Zhou W, Na SY, Hämmerling GJ, Garbi N, Karcher S, et al. Boosting regulatory T cells limits neuroinflammation in permanent cortical stroke. J Neurosci. 2013;33:17350-17362. doi: 10.1523/JNEUROSCI.4901-12.2013.
-
(2013)
J Neurosci
, vol.33
, pp. 17350-17362
-
-
Liesz, A.1
Zhou, W.2
Na, S.Y.3
Hämmerling, G.J.4
Garbi, N.5
Karcher, S.6
-
23
-
-
84873019070
-
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
-
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, et al. Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood. 2013;121:679-691. doi: 10.1182/blood-2012-04-426734.
-
(2013)
Blood
, vol.121
, pp. 679-691
-
-
Kleinschnitz, C.1
Kraft, P.2
Dreykluft, A.3
Hagedorn, I.4
Göbel, K.5
Schuhmann, M.K.6
-
24
-
-
84902203576
-
MTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia
-
Xie L, Sun F, Wang J, Mao X, Xie L, Yang SH, et al. mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia. J Immunol. 2014;192:6009-6019. doi: 10.4049/jimmunol.1303492.
-
(2014)
J Immunol
, vol.192
, pp. 6009-6019
-
-
Xie, L.1
Sun, F.2
Wang, J.3
Mao, X.4
Xie, L.5
Yang, S.H.6
-
25
-
-
79955083477
-
CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke
-
Ren X, Akiyoshi K, Vandenbark AA, Hurn PD, Offner H. CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke. Metab Brain Dis. 2011;26:87-90. doi: 10.1007/s11011-010-9226-6.
-
(2011)
Metab Brain Dis
, vol.26
, pp. 87-90
-
-
Ren, X.1
Akiyoshi, K.2
Vandenbark, A.A.3
Hurn, P.D.4
Offner, H.5
-
26
-
-
84891547893
-
Adoptive regulatory T-cell therapy protects against cerebral ischemia
-
Li P, Gan Y, Sun BL, Zhang F, Lu B, Gao Y, et al. Adoptive regulatory T-cell therapy protects against cerebral ischemia. Ann Neurol. 2013;74:458-471. doi: 10.1002/ana.23815.
-
(2013)
Ann Neurol
, vol.74
, pp. 458-471
-
-
Li, P.1
Gan, Y.2
Sun, B.L.3
Zhang, F.4
Lu, B.5
Gao, Y.6
-
27
-
-
84880764800
-
Con: Regulatory T cells are protective in ischemic stroke
-
Kleinschnitz C, Wiendl H. Con: regulatory T cells are protective in ischemic stroke. Stroke. 2013;44:e87-e88. doi: 10.1161/STROKEAHA.113.001268.
-
(2013)
Stroke
, vol.44
, pp. e87-e88
-
-
Kleinschnitz, C.1
Wiendl, H.2
-
28
-
-
84880795092
-
Pro: Regulatory T cells are protective in ischemic stroke
-
Hu X, Li P, Chen J. Pro: regulatory T cells are protective in ischemic stroke. Stroke. 2013;44:e85-e86. doi: 10.1161/STROKEAHA.113.001267.
-
(2013)
Stroke
, vol.44
, pp. e85-e86
-
-
Hu, X.1
Li, P.2
Chen, J.3
-
29
-
-
59349112750
-
Harms and benefits of lymphocyte subpopulations in patients with acute stroke
-
Urra X, Cervera A, Villamor N, Planas AM, Chamorro A. Harms and benefits of lymphocyte subpopulations in patients with acute stroke. Neuroscience. 2009;158:1174-1183. doi: 10.1016/j.neuroscience.2008.06.014.
-
(2009)
Neuroscience
, vol.158
, pp. 1174-1183
-
-
Urra, X.1
Cervera, A.2
Villamor, N.3
Planas, A.M.4
Chamorro, A.5
-
30
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol. 2007;8:191-197. doi: 10.1038/ni1428.
-
(2007)
Nat Immunol
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
31
-
-
77949900562
-
Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice
-
Suffner J, Hochweller K, Kühnle MC, Li X, Kroczek RA, Garbi N, et al. Dendritic cells support homeostatic expansion of Foxp3+ regulatory T cells in Foxp3.LuciDTR mice. J Immunol. 2010;184:1810-1820. doi: 10.4049/jimmunol.0902420.
-
(2010)
J Immunol
, vol.184
, pp. 1810-1820
-
-
Suffner, J.1
Hochweller, K.2
Kühnle, M.C.3
Li, X.4
Kroczek, R.A.5
Garbi, N.6
-
32
-
-
33846423147
-
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
-
Lahl K, Loddenkemper C, Drouin C, Freyer J, Arnason J, Eberl G, et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J Exp Med. 2007;204:57-63. doi: 10.1084/jem.20061852.
-
(2007)
J Exp Med
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
-
33
-
-
44449167217
-
Induction of immunologic tolerance to myelin basic protein prevents central nervous system autoimmunity and improves outcome after stroke
-
Gee JM, Kalil A, Thullbery M, Becker KJ. Induction of immunologic tolerance to myelin basic protein prevents central nervous system autoimmunity and improves outcome after stroke. Stroke. 2008;39:1575-1582. doi: 10.1161/STROKEAHA.107.501486.
-
(2008)
Stroke
, vol.39
, pp. 1575-1582
-
-
Gee, J.M.1
Kalil, A.2
Thullbery, M.3
Becker, K.J.4
-
34
-
-
61349199500
-
Mucosal tolerance to E-selectin promotes the survival of newly generated neuroblasts via regulatory T-cell induction after stroke in spontaneously hypertensive rats
-
Ishibashi S, Maric D, Mou Y, Ohtani R, Ruetzler C, Hallenbeck JM. Mucosal tolerance to E-selectin promotes the survival of newly generated neuroblasts via regulatory T-cell induction after stroke in spontaneously hypertensive rats. J Cereb Blood Flow Metab. 2009;29:606-620. doi: 10.1038/jcbfm.2008.153.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 606-620
-
-
Ishibashi, S.1
Maric, D.2
Mou, Y.3
Ohtani, R.4
Ruetzler, C.5
Hallenbeck, J.M.6
-
35
-
-
84912521059
-
Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia
-
Brea D, Agulla J, Rodríguez-Yáñez M, Barral D, Ramos-Cabrer P, Campos F, et al. Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia. J Cell Mol Med. 2014;18:1571-1579. doi: 10.1111/jcmm.12304.
-
(2014)
J Cell Mol Med
, vol.18
, pp. 1571-1579
-
-
Brea, D.1
Agulla, J.2
Rodríguez-Yáñez, M.3
Barral, D.4
Ramos-Cabrer, P.5
Campos, F.6
-
36
-
-
0345598137
-
Mucosal tolerance to E-selectin provides cell-mediated protection against ischemic brain injury
-
Chen Y, Ruetzler C, Pandipati S, Spatz M, McCarron RM, Becker K, et al. Mucosal tolerance to E-selectin provides cell-mediated protection against ischemic brain injury. Proc Natl Acad Sci U S A. 2003;100:15107-15112. doi: 10.1073/pnas.2436538100.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15107-15112
-
-
Chen, Y.1
Ruetzler, C.2
Pandipati, S.3
Spatz, M.4
McCarron, R.M.5
Becker, K.6
-
37
-
-
84899146822
-
Essential role of program death 1-ligand 1 in regulatory T-cell-afforded protection against blood-brain barrier damage after stroke
-
Li P, Mao L, Liu X, Gan Y, Zheng J, Thomson AW, et al. Essential role of program death 1-ligand 1 in regulatory T-cell-afforded protection against blood-brain barrier damage after stroke. Stroke. 2014;45:857-864. doi: 10.1161/STROKEAHA.113.004100.
-
(2014)
Stroke
, vol.45
, pp. 857-864
-
-
Li, P.1
Mao, L.2
Liu, X.3
Gan, Y.4
Zheng, J.5
Thomson, A.W.6
-
38
-
-
84889258454
-
Adoptive regulatory T-cell therapy preserves systemic immune homeostasis after cerebral ischemia
-
Li P, Mao L, Zhou G, Leak RK, Sun BL, Chen J, et al. Adoptive regulatory T-cell therapy preserves systemic immune homeostasis after cerebral ischemia. Stroke. 2013;44:3509-3515. doi: 10.1161/STROKEAHA.113.002637.
-
(2013)
Stroke
, vol.44
, pp. 3509-3515
-
-
Li, P.1
Mao, L.2
Zhou, G.3
Leak, R.K.4
Sun, B.L.5
Chen, J.6
-
39
-
-
84920167551
-
Amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice
-
Na SY, Mracsko E, Liesz A, Hünig T, Veltkamp R. Amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice. Stroke. 2015;46:212-220. doi: 10.1161/STROKEAHA.114.007756.
-
(2015)
Stroke
, vol.46
, pp. 212-220
-
-
Na, S.Y.1
Mracsko, E.2
Liesz, A.3
Hünig, T.4
Veltkamp, R.5
-
40
-
-
84920675365
-
CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke
-
Schuhmann MK, Kraft P, Stoll G, Lorenz K, Meuth SG, Wiendl H, et al. CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke. J Cereb Blood Flow Metab. 2015;35:6-10. doi: 10.1038/jcbfm.2014.175.
-
(2015)
J Cereb Blood Flow Metab
, vol.35
, pp. 6-10
-
-
Schuhmann, M.K.1
Kraft, P.2
Stoll, G.3
Lorenz, K.4
Meuth, S.G.5
Wiendl, H.6
-
41
-
-
65549136983
-
Mechanisms of foxp3+ T regulatory cell-mediated suppression
-
Shevach EM. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity. 2009;30:636-645. doi: 10.1016/j.immuni.2009.04.010.
-
(2009)
Immunity
, vol.30
, pp. 636-645
-
-
Shevach, E.M.1
-
43
-
-
0033930743
-
Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage
-
Grilli M, Barbieri I, Basudev H, Brusa R, Casati C, Lozza G, et al. Interleukin-10 modulates neuronal threshold of vulnerability to ischaemic damage. Eur J Neurosci. 2000;12:2265-2272.
-
(2000)
Eur J Neurosci
, vol.12
, pp. 2265-2272
-
-
Grilli, M.1
Barbieri, I.2
Basudev, H.3
Brusa, R.4
Casati, C.5
Lozza, G.6
-
44
-
-
84890206292
-
IL-10-producing B-cells limit CNS inflammation and infarct volume in experimental stroke
-
Bodhankar S, Chen Y, Vandenbark AA, Murphy SJ, Offner H. IL-10-producing B-cells limit CNS inflammation and infarct volume in experimental stroke. Metab Brain Dis. 2013;28:375-386. doi: 10.1007/s11011-013-9413-3.
-
(2013)
Metab Brain Dis
, vol.28
, pp. 375-386
-
-
Bodhankar, S.1
Chen, Y.2
Vandenbark, A.A.3
Murphy, S.J.4
Offner, H.5
-
45
-
-
84904640995
-
Intracerebral interleukin-10 injection modulates post-ischemic neuroinflammation: An experimental microarray study
-
Liesz A, Bauer A, Hoheisel JD, Veltkamp R. Intracerebral interleukin-10 injection modulates post-ischemic neuroinflammation: an experimental microarray study. Neurosci Lett. 2014;579:18-23. doi: 10.1016/j. neulet.2014.07.003.
-
(2014)
Neurosci Lett
, vol.579
, pp. 18-23
-
-
Liesz, A.1
Bauer, A.2
Hoheisel, J.D.3
Veltkamp, R.4
-
46
-
-
85047692430
-
IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
-
O'Garra A, Vieira PL, Vieira P, Goldfeld AE. IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest. 2004;114:1372-1378. doi: 10.1172/JCI23215.
-
(2004)
J Clin Invest
, vol.114
, pp. 1372-1378
-
-
O'garra, A.1
Vieira, P.L.2
Vieira, P.3
Goldfeld, A.E.4
-
47
-
-
0346366987
-
Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells
-
Frenkel D, Huang Z, Maron R, Koldzic DN, Hancock WW, Moskowitz MA, et al. Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells. J Immunol. 2003;171:6549-6555.
-
(2003)
J Immunol
, vol.171
, pp. 6549-6555
-
-
Frenkel, D.1
Huang, Z.2
Maron, R.3
Koldzic, D.N.4
Hancock, W.W.5
Moskowitz, M.A.6
-
48
-
-
20444371569
-
Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke
-
Frenkel D, Huang Z, Maron R, Koldzic DN, Moskowitz MA, Weiner HL. Neuroprotection by IL-10-producing MOG CD4+ T cells following ischemic stroke. J Neurol Sci. 2005;233:125-132. doi: 10.1016/j. jns.2005.03.022.
-
(2005)
J Neurol Sci
, vol.233
, pp. 125-132
-
-
Frenkel, D.1
Huang, Z.2
Maron, R.3
Koldzic, D.N.4
Moskowitz, M.A.5
Weiner, H.L.6
-
49
-
-
0035728362
-
Interleukin-10 in the brain
-
Strle K, Zhou JH, Shen WH, Broussard SR, Johnson RW, Freund GG, et al. Interleukin-10 in the brain. Crit Rev Immunol. 2001;21:427-449.
-
(2001)
Crit Rev Immunol
, vol.21
, pp. 427-449
-
-
Strle, K.1
Zhou, J.H.2
Shen, W.H.3
Broussard, S.R.4
Johnson, R.W.5
Freund, G.G.6
-
50
-
-
84883493901
-
PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1
-
Bodhankar S, Chen Y, Vandenbark AA, Murphy SJ, Offner H. PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1. J Neuroinflammation. 2013;10:111. doi: 10.1186/1742-2094-10-111.
-
(2013)
J Neuroinflammation
, vol.10
, pp. 111
-
-
Bodhankar, S.1
Chen, Y.2
Vandenbark, A.A.3
Murphy, S.J.4
Offner, H.5
-
51
-
-
79958265647
-
Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke
-
Ren X, Akiyoshi K, Dziennis S, Vandenbark AA, Herson PS, Hurn PD, et al. Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke. J Neurosci. 2011;31:8556-8563. doi: 10.1523/JNEUROSCI.1623-11.2011.
-
(2011)
J Neurosci
, vol.31
, pp. 8556-8563
-
-
Ren, X.1
Akiyoshi, K.2
Dziennis, S.3
Vandenbark, A.A.4
Herson, P.S.5
Hurn, P.D.6
-
52
-
-
33646454450
-
Role of T lymphocytes and interferon-gamma in ischemic stroke
-
Yilmaz G, Arumugam TV, Stokes KY, Granger DN. Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation. 2006;113:2105-2112. doi: 10.1161/CIRCULATIONAHA.105.593046.
-
(2006)
Circulation
, vol.113
, pp. 2105-2112
-
-
Yilmaz, G.1
Arumugam, T.V.2
Stokes, K.Y.3
Granger, D.N.4
-
53
-
-
77952557777
-
Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation
-
Kleinschnitz C, Schwab N, Kraft P, Hagedorn I, Dreykluft A, Schwarz T, et al. Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation. Blood. 2010;115:3835-3842. doi: 10.1182/blood-2009-10-249078.
-
(2010)
Blood
, vol.115
, pp. 3835-3842
-
-
Kleinschnitz, C.1
Schwab, N.2
Kraft, P.3
Hagedorn, I.4
Dreykluft, A.5
Schwarz, T.6
-
54
-
-
84865707531
-
A novel hypothesis: Regulatory B lymphocytes shape outcome from experimental stroke
-
Offner H, Hurn PD. A novel hypothesis: regulatory B lymphocytes shape outcome from experimental stroke. Transl Stroke Res. 2012;3:324-330. doi: 10.1007/s12975-012-0187-4.
-
(2012)
Transl Stroke Res
, vol.3
, pp. 324-330
-
-
Offner, H.1
Hurn, P.D.2
-
55
-
-
84895877893
-
Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice
-
Bodhankar S, Chen Y, Vandenbark AA, Murphy SJ, Offner H. Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice. Metab Brain Dis. 2014;29:59-73. doi: 10.1007/s11011-013-9474-3.
-
(2014)
Metab Brain Dis
, vol.29
, pp. 59-73
-
-
Bodhankar, S.1
Chen, Y.2
Vandenbark, A.A.3
Murphy, S.J.4
Offner, H.5
-
56
-
-
84871453759
-
Intrastriatal B-cell administration limits infarct size after stroke in B-cell deficient mice
-
Chen Y, Bodhankar S, Murphy SJ, Vandenbark AA, Alkayed NJ, Offner H. Intrastriatal B-cell administration limits infarct size after stroke in B-cell deficient mice. Metab Brain Dis. 2012;27:487-493. doi: 10.1007/s11011-012-9317-7.
-
(2012)
Metab Brain Dis
, vol.27
, pp. 487-493
-
-
Chen, Y.1
Bodhankar, S.2
Murphy, S.J.3
Vandenbark, A.A.4
Alkayed, N.J.5
Offner, H.6
-
57
-
-
84942943769
-
Regulatory CD8+CD122+ T-cells predominate in CNS after treatment of experimental stroke in male mice with IL-10-secreting b-cells
-
published online ahead of print December 25 Accessed February 26, 2015
-
Bodhankar S, Chen Y, Lapato A, Vandenbark AA, Murphy SJ, Saugstad JA, et al. Regulatory CD8+CD122+ T-cells predominate in CNS after treatment of experimental stroke in male mice with IL-10-secreting b-cells [published online ahead of print December 25, 2014]. Metab Brain Dis. http://link.springer.com/article/10.1007/s11011-014-9639-8. Accessed February 26, 2015.
-
(2014)
Metab Brain Dis
-
-
Bodhankar, S.1
Chen, Y.2
Lapato, A.3
Vandenbark, A.A.4
Murphy, S.J.5
Saugstad, J.A.6
-
58
-
-
33646382597
-
Experimental stroke induces massive, rapid activation of the peripheral immune system
-
Offner H, Subramanian S, Parker SM, Afentoulis ME, Vandenbark AA, Hurn PD. Experimental stroke induces massive, rapid activation of the peripheral immune system. J Cereb Blood Flow Metab. 2006;26:654-665. doi: 10.1038/sj.jcbfm.9600217.
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 654-665
-
-
Offner, H.1
Subramanian, S.2
Parker, S.M.3
Afentoulis, M.E.4
Vandenbark, A.A.5
Hurn, P.D.6
-
59
-
-
27944503933
-
Central nervous system injury-induced immune deficiency syndrome
-
Meisel C, Schwab JM, Prass K, Meisel A, Dirnagl U. Central nervous system injury-induced immune deficiency syndrome. Nat Rev Neurosci. 2005;6:775-786. doi: 10.1038/nrn1765.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 775-786
-
-
Meisel, C.1
Schwab, J.M.2
Prass, K.3
Meisel, A.4
Dirnagl, U.5
-
60
-
-
33646874015
-
Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages
-
Offner H, Subramanian S, Parker SM, Wang C, Afentoulis ME, Lewis A, et al. Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages. J Immunol. 2006;176:6523-6531.
-
(2006)
J Immunol
, vol.176
, pp. 6523-6531
-
-
Offner, H.1
Subramanian, S.2
Parker, S.M.3
Wang, C.4
Afentoulis, M.E.5
Lewis, A.6
-
61
-
-
68749099666
-
The spectrum of systemic immune alterations after murine focal ischemia: Immunodepression versus immunomodulation
-
Liesz A, Hagmann S, Zschoche C, Adamek J, Zhou W, Sun L, et al. The spectrum of systemic immune alterations after murine focal ischemia: immunodepression versus immunomodulation. Stroke. 2009;40:2849-2858. doi: 10.1161/STROKEAHA.109.549618.
-
(2009)
Stroke
, vol.40
, pp. 2849-2858
-
-
Liesz, A.1
Hagmann, S.2
Zschoche, C.3
Adamek, J.4
Zhou, W.5
Sun, L.6
-
62
-
-
84891010156
-
Amelioration of experimental arthritis by stroke-induced immunosuppression is independent of Treg cell function
-
Irmler IM, Gajda M, Kamradt T. Amelioration of experimental arthritis by stroke-induced immunosuppression is independent of Treg cell function. Ann Rheum Dis. 2014;73:2183-2191. doi: 10.1136/annrheumdis-2013-204148.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 2183-2191
-
-
Irmler, I.M.1
Gajda, M.2
Kamradt, T.3
-
63
-
-
84920943309
-
DAMP signaling is a key pathway inducing immune modulation after brain injury
-
Liesz A, Dalpke A, Mracsko E, Antoine DJ, Roth S, Zhou W, et al. DAMP signaling is a key pathway inducing immune modulation after brain injury. J Neurosci. 2015;35:583-598. doi: 10.1523/JNEUROSCI.2439-14.2015.
-
(2015)
J Neurosci
, vol.35
, pp. 583-598
-
-
Liesz, A.1
Dalpke, A.2
Mracsko, E.3
Antoine, D.J.4
Roth, S.5
Zhou, W.6
-
64
-
-
84919452225
-
Cerebral ischemia increases bone marrow CD4+CD25+FoxP3+ regulatory T cells in mice via signals from sympathetic nervous system
-
Wang J, Yu L, Jiang C, Fu X, Liu X, Wang M, et al. Cerebral ischemia increases bone marrow CD4+CD25+FoxP3+ regulatory T cells in mice via signals from sympathetic nervous system. Brain Behav Immun. 2015;43:172-183. doi: 10.1016/j.bbi.2014.07.022.
-
(2015)
Brain Behav Immun
, vol.43
, pp. 172-183
-
-
Wang, J.1
Yu, L.2
Jiang, C.3
Fu, X.4
Liu, X.5
Wang, M.6
-
65
-
-
84924427977
-
Ischemic stroke activates hematopoietic bone marrow stem cells
-
Courties G, Herisson F, Sager H, Heidt T, Ye Y, Ying W, et al. Ischemic stroke activates hematopoietic bone marrow stem cells. Circ Res. 2015;116:407-417.
-
(2015)
Circ Res
, vol.116
, pp. 407-417
-
-
Courties, G.1
Herisson, F.2
Sager, H.3
Heidt, T.4
Ye, Y.5
Ying, W.6
-
66
-
-
84856209332
-
Reduced efficacy of circulating costimulatory cells after focal cerebral ischemia
-
Hug A, Liesz A, Muerle B, Zhou W, Ehrenheim J, Lorenz A, et al. Reduced efficacy of circulating costimulatory cells after focal cerebral ischemia. Stroke. 2011;42:3580-3586. doi: 10.1161/STROKEAHA.111.620948.
-
(2011)
Stroke
, vol.42
, pp. 3580-3586
-
-
Hug, A.1
Liesz, A.2
Muerle, B.3
Zhou, W.4
Ehrenheim, J.5
Lorenz, A.6
-
67
-
-
84856955229
-
Frequency and function of regulatory T cells after ischaemic stroke in humans
-
Yan J, Read SJ, Henderson RD, Hull R, O'Sullivan JD, McCombe PA, et al. Frequency and function of regulatory T cells after ischaemic stroke in humans. J Neuroimmunol. 2012;243:89-94. doi: 10.1016/j. jneuroim.2011.12.019.
-
(2012)
J Neuroimmunol
, vol.243
, pp. 89-94
-
-
Yan, J.1
Read, S.J.2
Henderson, R.D.3
Hull, R.4
O'sullivan, J.D.5
McCombe, P.A.6
-
68
-
-
84882993930
-
Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction
-
Li Q, Wang Y, Yu F, Wang YM, Zhang C, Hu C, et al. Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction. Int J Clin Exp Pathol. 2013;6:1015-1027.
-
(2013)
Int J Clin Exp Pathol
, vol.6
, pp. 1015-1027
-
-
Li, Q.1
Wang, Y.2
Yu, F.3
Wang, Y.M.4
Zhang, C.5
Hu, C.6
-
69
-
-
84864282662
-
Low levels of circulating CD4+FoxP3+ T cells are associated with an increased risk for development of myocardial infarction but not for stroke
-
Wigren M, Björkbacka H, Andersson L, Ljungcrantz I, Fredrikson GN, Persson M, et al. Low levels of circulating CD4+FoxP3+ T cells are associated with an increased risk for development of myocardial infarction but not for stroke. Arterioscler Thromb Vasc Biol. 2012;32:2000-2004. doi: 10.1161/ATVBAHA.112.251579.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2000-2004
-
-
Wigren, M.1
Björkbacka, H.2
Andersson, L.3
Ljungcrantz, I.4
Fredrikson, G.N.5
Persson, M.6
-
70
-
-
84863496244
-
The two pathophysiologies of focal brain ischemia: Implications for translational stroke research
-
Hossmann KA. The two pathophysiologies of focal brain ischemia: implications for translational stroke research. J Cereb Blood Flow Metab. 2012;32:1310-1316. doi: 10.1038/jcbfm.2011.186.
-
(2012)
J Cereb Blood Flow Metab
, vol.32
, pp. 1310-1316
-
-
Hossmann, K.A.1
-
71
-
-
84896785354
-
Lack of secondary microthrombosis after thrombin-induced stroke in mice and nonhuman primates
-
Gauberti M, Martinez de Lizarrondo S, Orset C, Vivien D. Lack of secondary microthrombosis after thrombin-induced stroke in mice and nonhuman primates. J Thromb Haemost. 2014;12:409-414. doi: 10.1111/jth.12487.
-
(2014)
J Thromb Haemost
, vol.12
, pp. 409-414
-
-
Gauberti, M.1
Martinez De Lizarrondo, S.2
Orset, C.3
Vivien, D.4
-
72
-
-
84863726869
-
The immunology of acute stroke
-
Chamorro Á, Meisel A, Planas AM, Urra X, van de Beek D, Veltkamp R. The immunology of acute stroke. Nat Rev Neurol. 2012;8:401-410. doi: 10.1038/nrneurol.2012.98.
-
(2012)
Nat Rev Neurol
, vol.8
, pp. 401-410
-
-
Chamorro Á.1
Meisel, A.2
Planas, A.M.3
Urra, X.4
Van De Beek, D.5
Veltkamp, R.6
-
73
-
-
84884373309
-
Stress mediators and immune dysfunction in patients with acute cerebrovascular diseases
-
Liesz A, Rüger H, Purrucker J, Zorn M, Dalpke A, Möhlenbruch M, et al. Stress mediators and immune dysfunction in patients with acute cerebrovascular diseases. PLoS One. 2013;8:e74839. doi: 10.1371/journal. pone.0074839.
-
(2013)
PLoS One
, vol.8
, pp. e74839
-
-
Liesz, A.1
Rüger, H.2
Purrucker, J.3
Zorn, M.4
Dalpke, A.5
Möhlenbruch, M.6
-
74
-
-
84896738742
-
Immune cell infiltration in malignant middle cerebral artery infarction: Comparison with transient cerebral ischemia
-
Chu HX, Kim HA, Lee S, Moore JP, Chan CT, Vinh A, et al. Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia. J Cereb Blood Flow Metab. 2014;34:450-459. doi: 10.1038/jcbfm.2013.217.
-
(2014)
J Cereb Blood Flow Metab
, vol.34
, pp. 450-459
-
-
Chu, H.X.1
Kim, H.A.2
Lee, S.3
Moore, J.P.4
Chan, C.T.5
Vinh, A.6
-
75
-
-
33751523588
-
Functional dynamics of naturally occurring regulatory T cells in health and autoimmunity
-
Levings MK, Allan S, d'Hennezel E, Piccirillo CA. Functional dynamics of naturally occurring regulatory T cells in health and autoimmunity. Adv Immunol. 2006;92:119-155. doi: 10.1016/S0065-2776(06)92003-3.
-
(2006)
Adv Immunol
, vol.92
, pp. 119-155
-
-
Levings, M.K.1
Allan, S.2
D'hennezel, E.3
Piccirillo, C.A.4
-
76
-
-
33947605421
-
The Janus face of CD4+CD25+ regulatory T cells in cancer and autoimmunity
-
Danese S, Rutella S. The Janus face of CD4+CD25+ regulatory T cells in cancer and autoimmunity. Curr Med Chem. 2007;14:649-666.
-
(2007)
Curr Med Chem
, vol.14
, pp. 649-666
-
-
Danese, S.1
Rutella, S.2
-
77
-
-
84904301649
-
Protective autoimmunity: A unifying model for the immune network involved in CNS repair
-
Schwartz M, Raposo C. Protective autoimmunity: a unifying model for the immune network involved in CNS repair. Neuroscientist. 2014;20:343-358. doi: 10.1177/1073858413516799.
-
(2014)
Neuroscientist
, vol.20
, pp. 343-358
-
-
Schwartz, M.1
Raposo, C.2
-
78
-
-
84910136028
-
Regulatory T cells in central nervous system injury: A double-edged sword
-
Walsh JT, Zheng J, Smirnov I, Lorenz U, Tung K, Kipnis J. Regulatory T cells in central nervous system injury: a double-edged sword. J Immunol. 2014;193:5013-5022. doi: 10.4049/jimmunol.1302401.
-
(2014)
J Immunol
, vol.193
, pp. 5013-5022
-
-
Walsh, J.T.1
Zheng, J.2
Smirnov, I.3
Lorenz, U.4
Tung, K.5
Kipnis, J.6
-
79
-
-
27144452325
-
Controlled autoimmunity in CNS maintenance and repair: Naturally occurring CD4+CD25+ regulatory T-Cells at the crossroads of health and disease
-
Kipnis J, Schwartz M. Controlled autoimmunity in CNS maintenance and repair: naturally occurring CD4+CD25+ regulatory T-Cells at the crossroads of health and disease. Neuromolecular Med. 2005;7:197-206. doi: 10.1385/NMM:7:3:197.
-
(2005)
Neuromolecular Med
, vol.7
, pp. 197-206
-
-
Kipnis, J.1
Schwartz, M.2
-
80
-
-
0037180556
-
Neuroprotective autoimmunity: Naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system
-
Kipnis J, Mizrahi T, Hauben E, Shaked I, Shevach E, Schwartz M. Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system. Proc Natl Acad Sci U S A. 2002;99:15620-15625. doi: 10.1073/pnas.232565399.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15620-15625
-
-
Kipnis, J.1
Mizrahi, T.2
Hauben, E.3
Shaked, I.4
Shevach, E.5
Schwartz, M.6
-
81
-
-
84901415559
-
Distinguishing between exploratory and confirmatory preclinical research will improve translation
-
Kimmelman J, Mogil JS, Dirnagl U. Distinguishing between exploratory and confirmatory preclinical research will improve translation. PLoS Biol. 2014;12:e1001863. doi: 10.1371/journal.pbio.1001863.
-
(2014)
PLoS Biol
, vol.12
, pp. e1001863
-
-
Kimmelman, J.1
Mogil, J.S.2
Dirnagl, U.3
-
82
-
-
84880147654
-
A concerted appeal for international cooperation in preclinical stroke research
-
Dirnagl U, Hakim A, Macleod M, Fisher M, Howells D, Alan SM, et al. A concerted appeal for international cooperation in preclinical stroke research. Stroke. 2013;44:1754-1760. doi: 10.1161/STROKEAHA.113.000734.
-
(2013)
Stroke
, vol.44
, pp. 1754-1760
-
-
Dirnagl, U.1
Hakim, A.2
Macleod, M.3
Fisher, M.4
Howells, D.5
Alan, S.M.6
|