-
1
-
-
79960141471
-
The immunology of stroke: From mechanisms to translation
-
Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nat Med. 2011;17:796-808.
-
(2011)
Nat Med.
, vol.17
, pp. 796-808
-
-
Iadecola, C.1
Anrather, J.2
-
2
-
-
79952175153
-
Inhibition of lymphocyte traffcking shields the brain against deleterious neuroinfammation after stroke
-
Liesz A, Zhou W, Mracsko E, Karcher S, Bauer H, Schwarting S, et al. Inhibition of lymphocyte traffcking shields the brain against deleterious neuroinfammation after stroke. Brain. 2011;134:704-720.
-
(2011)
Brain.
, vol.134
, pp. 704-720
-
-
Liesz, A.1
Zhou, W.2
Mracsko, E.3
Karcher, S.4
Bauer, H.5
Schwarting, S.6
-
4
-
-
68349160698
-
Pivotal role of cerebral interleukin-17-producing gammad-eltaT cells in the delayed phase of ischemic brain injury
-
Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I, et al. Pivotal role of cerebral interleukin-17-producing gammad-eltaT cells in the delayed phase of ischemic brain injury. Nat Med. 2009;15:946-950.
-
(2009)
Nat Med.
, vol.15
, pp. 946-950
-
-
Shichita, T.1
Sugiyama, Y.2
Ooboshi, H.3
Sugimori, H.4
Nakagawa, R.5
Takada, I.6
-
5
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol. 2004;22:531-562.
-
(2004)
Annu Rev Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
6
-
-
84873019070
-
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
-
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, et al. Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood. 2013;121:679-691.
-
(2013)
Blood.
, vol.121
, pp. 679-691
-
-
Kleinschnitz, C.1
Kraft, P.2
Dreykluft, A.3
Hagedorn, I.4
Göbel, K.5
Schuhmann, M.K.6
-
7
-
-
59649123881
-
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
-
Liesz A, Suri-Payer E, Veltkamp C, Doerr H, Sommer C, Rivest S, et al. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat Med. 2009;15:192-199.
-
(2009)
Nat Med.
, vol.15
, pp. 192-199
-
-
Liesz, A.1
Suri-Payer, E.2
Veltkamp, C.3
Doerr, H.4
Sommer, C.5
Rivest, S.6
-
8
-
-
79955083477
-
CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke
-
Ren X, Akiyoshi K, Vandenbark AA, Hurn PD, Offner H. CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke. Metab Brain Dis. 2011;26:87-90.
-
(2011)
Metab Brain Dis.
, vol.26
, pp. 87-90
-
-
Ren, X.1
Akiyoshi, K.2
Vandenbark, A.A.3
Hurn, P.D.4
Offner, H.5
-
9
-
-
84871928577
-
Regulatory t cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO
-
Stubbe T, Ebner F, Richter D, Engel O, Klehmet J, Royl G, et al. Regulatory t cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO. J Cereb Blood Flow Metab. 2013;33:37-47.
-
(2013)
J Cereb Blood Flow Metab.
, vol.33
, pp. 37-47
-
-
Stubbe, T.1
Ebner, F.2
Richter, D.3
Engel, O.4
Klehmet, J.5
Royl, G.6
-
10
-
-
84891547893
-
Adoptive regulatory T-cell therapy protects against cerebral ischemia
-
Li P, Gan Y, Sun BL, Zhang F, Lu B, Gao Y, et al. Adoptive regulatory T-cell therapy protects against cerebral ischemia. Ann Neurol. 2013;74:458-471.
-
(2013)
Ann Neurol.
, vol.74
, pp. 458-471
-
-
Li, P.1
Gan, Y.2
Sun, B.L.3
Zhang, F.4
Lu, B.5
Gao, Y.6
-
11
-
-
84886702007
-
Boosting regulatory T cells limits neuroinfammation in permanent cortical stroke
-
Liesz A, Zhou W, Na SY, Hämmerling GJ, Garbi N, Karcher S, et al. Boosting regulatory T cells limits neuroinfammation in permanent cortical stroke. J Neurosci. 2013;33:17350-17362.
-
(2013)
J Neurosci.
, vol.33
, pp. 17350-17362
-
-
Liesz, A.1
Zhou, W.2
Na, S.Y.3
Hämmerling, G.J.4
Garbi, N.5
Karcher, S.6
-
12
-
-
84902203576
-
MTOR signaling inhibition modulates macrophage/microglia-mediated neuroinfamma-tion and secondary injury via regulatory T cells after focal ischemia
-
Xie L, Sun F, Wang J, Mao X, Xie L, Yang SH, et al. mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinfamma-tion and secondary injury via regulatory T cells after focal ischemia. J Immunol. 2014;192:6009-6019.
-
(2014)
J Immunol.
, vol.192
, pp. 6009-6019
-
-
Xie, L.1
Sun, F.2
Wang, J.3
Mao, X.4
Xie, L.5
Yang, S.H.6
-
13
-
-
84864279250
-
Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice
-
Gogishvili T, Langenhorst D, Lühder F, Elias F, Elfein K, Dennehy KM, et al. Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice. PLoS One. 2009;4:e4643.
-
(2009)
PLoS One.
, vol.4
, pp. e4643
-
-
Gogishvili, T.1
Langenhorst, D.2
Lühder, F.3
Elias, F.4
Elfein, K.5
Dennehy, K.M.6
-
14
-
-
0037352740
-
Effcient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist
-
Lin CH, Hünig T. Effcient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist. Eur J Immunol. 2003;33:626-638.
-
(2003)
Eur J Immunol.
, vol.33
, pp. 626-638
-
-
Lin, C.H.1
Hünig, T.2
-
15
-
-
23744517125
-
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis
-
Beyersdorf N, Gaupp S, Balbach K, Schmidt J, Toyka KV, Lin CH, et al. Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J Exp Med. 2005;202:445-455.
-
(2005)
J Exp Med.
, vol.202
, pp. 445-455
-
-
Beyersdorf, N.1
Gaupp, S.2
Balbach, K.3
Schmidt, J.4
Toyka, K.V.5
Lin, C.H.6
-
16
-
-
0038643708
-
Treatment and prevention of experimental autoimmune neuritis with superagonistic CD28-specifc monoclonal antibodies
-
Schmidt J, Elfein K, Stienekemeier M, Rodriguez-Palmero M, Schneider C, Toyka KV, et al. Treatment and prevention of experimental autoimmune neuritis with superagonistic CD28-specifc monoclonal antibodies. J Neuroimmunol. 2003;140:143-152.
-
(2003)
J Neuroimmunol.
, vol.140
, pp. 143-152
-
-
Schmidt, J.1
Elfein, K.2
Stienekemeier, M.3
Rodriguez-Palmero, M.4
Schneider, C.5
Toyka, K.V.6
-
17
-
-
33745225894
-
Costimulation and autoimmune diabetes in bb rats
-
Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, et al. Costimulation and autoimmune diabetes in bb rats. Am J Transplant. 2006;6:894-902.
-
(2006)
Am J Transplant.
, vol.6
, pp. 894-902
-
-
Beaudette-Zlatanova, B.C.1
Whalen, B.2
Zipris, D.3
Yagita, H.4
Rozing, J.5
Groen, H.6
-
18
-
-
73349132995
-
Superagonistic CD28 stimulation of allogeneic T cells protects from acute graft-versus-host disease
-
Beyersdorf N, Ding X, Hünig T, Kerkau T. Superagonistic CD28 stimulation of allogeneic T cells protects from acute graft-versus-host disease. Blood. 2009;114:4575-4582.
-
(2009)
Blood.
, vol.114
, pp. 4575-4582
-
-
Beyersdorf, N.1
Ding, X.2
Hünig, T.3
Kerkau, T.4
-
19
-
-
50949124542
-
Experimental expansion of the regulatory T cell population increases resistance to African trypanosomiasis
-
Guilliams M, Bosschaerts T, Hérin M, Hünig T, Loi P, Flamand V, et al. Experimental expansion of the regulatory T cell population increases resistance to African trypanosomiasis. J Infect Dis. 2008;198:781-791.
-
(2008)
J Infect Dis.
, vol.198
, pp. 781-791
-
-
Guilliams, M.1
Bosschaerts, T.2
Hérin, M.3
Hünig, T.4
Loi, P.5
Flamand, V.6
-
21
-
-
0037199090
-
A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia
-
Zhang L, Schallert T, Zhang ZG, Jiang Q, Arniego P, Li Q, et al. A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia. J Neurosci Methods. 2002;117:207-214.
-
(2002)
J Neurosci Methods.
, vol.117
, pp. 207-214
-
-
Zhang, L.1
Schallert, T.2
Zhang, Z.G.3
Jiang, Q.4
Arniego, P.5
Li, Q.6
-
22
-
-
0022504946
-
Recovery of function after brain damage: Severe and chronic disruption by diazepam
-
Schallert T, Hernandez TD, Barth TM. Recovery of function after brain damage: severe and chronic disruption by diazepam. Brain Res. 1986;379:104-111.
-
(1986)
Brain Res.
, vol.379
, pp. 104-111
-
-
Schallert, T.1
Hernandez, T.D.2
Barth, T.M.3
-
23
-
-
84870589141
-
Sequential induction of effector function, tissue migration and cell death during polyclonal activation of mouse regulatory T-cells
-
Langenhorst D, Gogishvili T, Ribechini E, Kneitz S, McPherson K, Lutz MB, et al. Sequential induction of effector function, tissue migration and cell death during polyclonal activation of mouse regulatory T-cells. PLoS One. 2012;7:e50080.
-
(2012)
PLoS One.
, vol.7
, pp. e50080
-
-
Langenhorst, D.1
Gogishvili, T.2
Ribechini, E.3
Kneitz, S.4
McPherson, K.5
Lutz, M.B.6
-
24
-
-
10744221289
-
Developmental stage, phenotype, and migration distinguish naive-and effector/memory-like CD4+ regulatory T cells
-
Huehn J, Siegmund K, Lehmann JC, Siewert C, Haubold U, Feuerer M, et al. Developmental stage, phenotype, and migration distinguish naive-and effector/memory-like CD4+ regulatory T cells. J Exp Med. 2004;199:303-313.
-
(2004)
J Exp Med.
, vol.199
, pp. 303-313
-
-
Huehn, J.1
Siegmund, K.2
Lehmann, J.C.3
Siewert, C.4
Haubold, U.5
Feuerer, M.6
-
25
-
-
27744528888
-
Homing to suppress: Address codes for Treg migration
-
Huehn J, Hamann A. Homing to suppress: address codes for Treg migration. Trends Immunol. 2005;26:632-636.
-
(2005)
Trends Immunol.
, vol.26
, pp. 632-636
-
-
Huehn, J.1
Hamann, A.2
-
26
-
-
68749099666
-
The spectrum of systemic immune alterations after murine focal ischemia: Immunodepression versus immunomodulation
-
Liesz A, Hagmann S, Zschoche C, Adamek J, Zhou W, Sun L, et al. The spectrum of systemic immune alterations after murine focal ischemia: immunodepression versus immunomodulation. Stroke. 2009;40:2849-2858.
-
(2009)
Stroke.
, vol.40
, pp. 2849-2858
-
-
Liesz, A.1
Hagmann, S.2
Zschoche, C.3
Adamek, J.4
Zhou, W.5
Sun, L.6
-
27
-
-
0036161092
-
Flow cyto-metric analysis of infammatory cells in ischemic rat brain
-
Campanella M, Sciorati C, Tarozzo G, Beltramo M. Flow cyto-metric analysis of infammatory cells in ischemic rat brain. Stroke. 2002;33:586-592.
-
(2002)
Stroke.
, vol.33
, pp. 586-592
-
-
Campanella, M.1
Sciorati, C.2
Tarozzo, G.3
Beltramo, M.4
-
28
-
-
84870893039
-
Postischemic brain infltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models
-
Zhou W, Liesz A, Bauer H, Sommer C, Lahrmann B, Valous N, et al. Postischemic brain infltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models. Brain Pathol. 2013;23:34-44.
-
(2013)
Brain Pathol.
, vol.23
, pp. 34-44
-
-
Zhou, W.1
Liesz, A.2
Bauer, H.3
Sommer, C.4
Lahrmann, B.5
Valous, N.6
-
29
-
-
35948980739
-
Deacetylase inhibition promotes the generation and function of regulatory T cells
-
Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, Porrett PM, et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med. 2007;13:1299-1307.
-
(2007)
Nat Med.
, vol.13
, pp. 1299-1307
-
-
Tao, R.1
De Zoeten, E.F.2
Ozkaynak, E.3
Chen, C.4
Wang, L.5
Porrett, P.M.6
-
30
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
Suntharalingam G, Perry MR, Ward S, Brett SJ, Castello-Cortes A, Brunner MD, et al. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med. 2006;355:1018-1028.
-
(2006)
N Engl J Med.
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
-
31
-
-
77956304908
-
Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells
-
Eastwood D, Findlay L, Poole S, Bird C, Wadhwa M, Moore M, et al. Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells. Br J Pharmacol. 2010;161:512-526.
-
(2010)
Br J Pharmacol.
, vol.161
, pp. 512-526
-
-
Eastwood, D.1
Findlay, L.2
Poole, S.3
Bird, C.4
Wadhwa, M.5
Moore, M.6
-
32
-
-
84255160968
-
Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412
-
Römer PS, Berr S, Avota E, Na SY, Battaglia M, ten Berge I, et al. Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412. Blood. 2011;118:6772-6782.
-
(2011)
Blood.
, vol.118
, pp. 6772-6782
-
-
Römer, P.S.1
Berr, S.2
Avota, E.3
Na, S.Y.4
Battaglia, M.5
Ten Berge, I.6
-
33
-
-
84860257860
-
The storm has cleared: Lessons from the CD28 superagonist TGN1412 trial
-
Hünig T. The storm has cleared: lessons from the CD28 superagonist TGN1412 trial. Nat Rev Immunol. 2012;12:317-318.
-
(2012)
Nat Rev Immunol.
, vol.12
, pp. 317-318
-
-
Hünig, T.1
-
34
-
-
84897979659
-
Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08
-
Tabares P, Berr S, Römer PS, Chuvpilo S, Matskevich AA, Tyrsin D, et al. Human regulatory T cells are selectively activated by low-dose application of the CD28 superagonist TGN1412/TAB08. Eur J Immunol. 2014;44:1225-1236.
-
(2014)
Eur J Immunol.
, vol.44
, pp. 1225-1236
-
-
Tabares, P.1
Berr, S.2
Römer, P.S.3
Chuvpilo, S.4
Matskevich, A.A.5
Tyrsin, D.6
-
35
-
-
79251500661
-
Phenotypical and functional specialization of FOXP3+ regulatory T cells
-
Campbell DJ, Koch MA. Phenotypical and functional specialization of FOXP3+ regulatory T cells. Nat Rev Immunol. 2011;11:119-130.
-
(2011)
Nat Rev Immunol.
, vol.11
, pp. 119-130
-
-
Campbell, D.J.1
Koch, M.A.2
|