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Volumn 16, Issue 7, 2015, Pages 15150-15171

Behavioral deficits are accompanied by immunological and neurochemical changes in a mouse model for neuropsychiatric lupus (NP-SLE)

Author keywords

3 dioxygenase (IDO); Anhedonia; Chemokines; Cytokines; Forced swim test; Indoleamine 2; Kynurenine; Lupus; MRL lpr; Novel object placement test

Indexed keywords

GAMMA INTERFERON; HAPTOGLOBIN; INTERLEUKIN 10; KYNURENINE; LYMPHOTACTIN; MONOCYTE CHEMOTACTIC PROTEIN; N METHYL DEXTRO ASPARTIC ACID; SEROTONIN; CHEMOKINE; CYTOKINE;

EID: 84936876686     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160715150     Document Type: Article
Times cited : (34)

References (120)
  • 1
    • 0035859774 scopus 로고    scopus 로고
    • The prevalence of neuropsychiatric syndromes in systemic lupus erythematosus
    • Ainiala, H.; Loukkola, J.; Peltola, J.; Korpela, M.; Hietaharju, A. The prevalence of neuropsychiatric syndromes in systemic lupus erythematosus. Neurology 2001, 57, 496-500.
    • (2001) Neurology , vol.57 , pp. 496-500
    • Ainiala, H.1    Loukkola, J.2    Peltola, J.3    Korpela, M.4    Hietaharju, A.5
  • 4
    • 0026793171 scopus 로고
    • Neuropsychiatric involvement in systemic lupus erythematosus
    • Putterman, C.; Naparstek, Y. Neuropsychiatric involvement in systemic lupus erythematosus. Isr. J. Med. Sci. 1992, 28, 458-460.
    • (1992) Isr. J. Med. Sci , vol.28 , pp. 458-460
    • Putterman, C.1    Naparstek, Y.2
  • 5
    • 84892160436 scopus 로고    scopus 로고
    • Neuropsychiatric lupus, the blood brain barrier, and the TWEAK/Fn14 pathway
    • Stock, A.D.; Wen, J.; Putterman, C. Neuropsychiatric lupus, the blood brain barrier, and the TWEAK/Fn14 pathway. Front. Immunol. 2013, 4, 484.
    • (2013) Front. Immunol , vol.4 , pp. 484
    • Stock, A.D.1    Wen, J.2    Putterman, C.3
  • 7
    • 0029007113 scopus 로고
    • Cognitive dysfunction in systemic lupus erythematosus is independent of active disease
    • Carbotte, R.M.; Denburg, S.D.; Denburg, J.A. Cognitive dysfunction in systemic lupus erythematosus is independent of active disease. J. Rheumatol. 1995, 22, 863-867.
    • (1995) J. Rheumatol , vol.22 , pp. 863-867
    • Carbotte, R.M.1    Denburg, S.D.2    Denburg, J.A.3
  • 10
    • 33750997606 scopus 로고    scopus 로고
    • Ibuprofen fails to prevent brain pathology in a model of neuropsychiatric lupus
    • Ballok, D.A.; Ma, X.; Denburg, J.A.; Arsenault, L.; Sakic, B. Ibuprofen fails to prevent brain pathology in a model of neuropsychiatric lupus. J. Rheumatol. 2006, 33, 2199-2213.
    • (2006) J. Rheumatol , vol.33 , pp. 2199-2213
    • Ballok, D.A.1    Ma, X.2    Denburg, J.A.3    Arsenault, L.4    Sakic, B.5
  • 11
    • 78650208478 scopus 로고    scopus 로고
    • Sex and autoantibody titers determine the development of neuropsychiatric manifestations in lupus-prone mice
    • Gao, H.X.; Sanders, E.; Tieng, A.T.; Putterman, C. Sex and autoantibody titers determine the development of neuropsychiatric manifestations in lupus-prone mice. J. Neuroimmunol. 2010, 229, 112-122.
    • (2010) J. Neuroimmunol , vol.229 , pp. 112-122
    • Gao, H.X.1    Sanders, E.2    Tieng, A.T.3    Putterman, C.4
  • 12
    • 79953291788 scopus 로고    scopus 로고
    • The MRL/lpr mouse strain as a model for neuropsychiatric systemic lupus erythematosus
    • Gulinello, M.; Putterman, C. The MRL/lpr mouse strain as a model for neuropsychiatric systemic lupus erythematosus. J. Biomed. Biotechnol. 2011, 2011, doi:10.1155/2011/207504.
    • (2011) J. Biomed. Biotechnol , pp. 2011
    • Gulinello, M.1    Putterman, C.2
  • 13
    • 0030931328 scopus 로고    scopus 로고
    • Behaviour of MRL mice: An animal model of disturbed behavior in systemic autoimmune disease
    • Szechtman, H.; Sakic, B.; Denburg, J.A. Behaviour of MRL mice: An animal model of disturbed behavior in systemic autoimmune disease. Lupus 1997, 6, 223-229.
    • (1997) Lupus , vol.6 , pp. 223-229
    • Szechtman, H.1    Sakic, B.2    Denburg, J.A.3
  • 14
    • 73149112607 scopus 로고    scopus 로고
    • Circulating brain-reactive autoantibodies and behavioral deficits in the MRL model of CNS lupus
    • Williams, S.; Sakic, B.; Hoffman, S.A. Circulating brain-reactive autoantibodies and behavioral deficits in the MRL model of CNS lupus. J. Neuroimmunol. 2010, 218, 73-82.
    • (2010) J. Neuroimmunol , vol.218 , pp. 73-82
    • Williams, S.1    Sakic, B.2    Hoffman, S.A.3
  • 17
    • 0031298341 scopus 로고    scopus 로고
    • Aberrant cytokine expression and autocrine regulation characterize macrophages from young MRL+/+ and NZB/W F1 lupus-prone mice
    • Alleva, D.G.; Kaser, S.B.; Beller, D.I. Aberrant cytokine expression and autocrine regulation characterize macrophages from young MRL+/+ and NZB/W F1 lupus-prone mice. J. Immunol. 1997, 159, 5610-5619.
    • (1997) J. Immunol , vol.159 , pp. 5610-5619
    • Alleva, D.G.1    Kaser, S.B.2    Beller, D.I.3
  • 18
    • 0032518439 scopus 로고    scopus 로고
    • Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
    • Balomenos, D.; Rumold, R.; Theofilopoulos, A.N. Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J. Clin. Investig. 1998, 101, 364-371.
    • (1998) J. Clin. Investig , vol.101 , pp. 364-371
    • Balomenos, D.1    Rumold, R.2    Theofilopoulos, A.N.3
  • 19
    • 0023718797 scopus 로고
    • Novel and enhanced IL-1 gene expression in autoimmune mice with lupus
    • Boswell, J.M.; Yui, M.A.; Endres, S.; Burt, D.W.; Kelley, V.E. Novel and enhanced IL-1 gene expression in autoimmune mice with lupus. J. Immunol. 1988, 141, 118-124.
    • (1988) J. Immunol , vol.141 , pp. 118-124
    • Boswell, J.M.1    Yui, M.A.2    Endres, S.3    Burt, D.W.4    Kelley, V.E.5
  • 20
    • 0037320208 scopus 로고    scopus 로고
    • Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice
    • Braun, D.; Geraldes, P.; Demengeot, J. Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice. J. Autoimmun. 2003, 20, 15-25.
    • (2003) J. Autoimmun , vol.20 , pp. 15-25
    • Braun, D.1    Geraldes, P.2    Demengeot, J.3
  • 22
    • 0034667989 scopus 로고    scopus 로고
    • Cytokine dysregulation induced by apoptotic cells is a shared characteristic of murine lupus
    • Koh, J.S.; Wang, Z.; Levine, J.S. Cytokine dysregulation induced by apoptotic cells is a shared characteristic of murine lupus. J. Immunol. 2000, 165, 4190-4201.
    • (2000) J. Immunol , vol.165 , pp. 4190-4201
    • Koh, J.S.1    Wang, Z.2    Levine, J.S.3
  • 23
    • 84906832163 scopus 로고    scopus 로고
    • The common inflammatory etiology of depression and cognitive impairment: A therapeutic target
    • Allison, D.J.; Ditor, D.S. The common inflammatory etiology of depression and cognitive impairment: A therapeutic target. J. Neuroinflamm. 2014, 11, 151.
    • (2014) J. Neuroinflamm , vol.11 , pp. 151
    • Allison, D.J.1    Ditor, D.S.2
  • 25
    • 84923286364 scopus 로고    scopus 로고
    • The importance of cytokines and autoantibodies in depression
    • Postal, M.; Appenzeller, S. The importance of cytokines and autoantibodies in depression. Autoimmun. Rev. 2015, 14, 30-35.
    • (2015) Autoimmun. Rev , vol.14 , pp. 30-35
    • Postal, M.1    Appenzeller, S.2
  • 26
    • 35349002824 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase activity is increased in patients with systemic lupus erythematosus and predicts disease activation in the sunny season
    • Pertovaara, M.; Hasan, T.; Raitala, A.; Oja, S.S.; Yli-Kerttula, U.; Korpela, M.; Hurme, M. Indoleamine 2,3-dioxygenase activity is increased in patients with systemic lupus erythematosus and predicts disease activation in the sunny season. Clin. Exp. Immunol. 2007, 150, 274-278.
    • (2007) Clin. Exp. Immunol , vol.150 , pp. 274-278
    • Pertovaara, M.1    Hasan, T.2    Raitala, A.3    Oja, S.S.4    Yli-Kerttula, U.5    Korpela, M.6    Hurme, M.7
  • 27
    • 0034466520 scopus 로고    scopus 로고
    • Degradation of tryptophan in patients with systemic lupus erythematosus
    • Widner, B.; Sepp, N.; Kowald, E.; Kind, S.; Schmuth, M.; Fuchs, D. Degradation of tryptophan in patients with systemic lupus erythematosus. Adv. Exp. Med. Biol. 1999, 467, 571-577.
    • (1999) Adv. Exp. Med. Biol , vol.467 , pp. 571-577
    • Widner, B.1    Sepp, N.2    Kowald, E.3    Kind, S.4    Schmuth, M.5    Fuchs, D.6
  • 29
    • 0037293033 scopus 로고    scopus 로고
    • Cytokines and depression: The need for a new paradigm
    • Capuron, L.; Dantzer, R. Cytokines and depression: The need for a new paradigm. Brain Behav. Immun. 2003, 17, S119-S124.
    • (2003) Brain Behav. Immun , vol.17 , pp. S119-S124
    • Capuron, L.1    Dantzer, R.2
  • 30
    • 84896502247 scopus 로고    scopus 로고
    • IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis
    • Merlo, L.M.; Pigott, E.; DuHadaway, J.B.; Grabler, S.; Metz, R.; Prendergast, G.C.; Mandik-Nayak, L. IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis. J. Immunol. 2014, 192, 2082-2090.
    • (2014) J. Immunol , vol.192 , pp. 2082-2090
    • Merlo, L.M.1    Pigott, E.2    Duhadaway, J.B.3    Grabler, S.4    Metz, R.5    Prendergast, G.C.6    Mandik-Nayak, L.7
  • 31
    • 34248581135 scopus 로고    scopus 로고
    • Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior
    • Frenois, F.; Moreau, M.; O’Connor, J.; Lawson, M.; Micon, C.; Lestage, J.; Kelley, K.W.; Dantzer, R.; Castanon, N. Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior. Psychoneuroendocrinology 2007, 32, 516-531.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 516-531
    • Frenois, F.1    Moreau, M.2    O’connor, J.3    Lawson, M.4    Micon, C.5    Lestage, J.6    Kelley, K.W.7    Dantzer, R.8    Castanon, N.9
  • 33
    • 65249156122 scopus 로고    scopus 로고
    • Interferon-γ and tumor necrosis factor-α mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin
    • O’Connor, J.C.; Andre, C.; Wang, Y.; Lawson, M.A.; Szegedi, S.S.; Lestage, J.; Castanon, N.; Kelley, K.W.; Dantzer, R. Interferon-γ and tumor necrosis factor-α mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin. J. Neurosci. 2009, 29, 4200-4209.
    • (2009) J. Neurosci , vol.29 , pp. 4200-4209
    • O’connor, J.C.1    Andre, C.2    Wang, Y.3    Lawson, M.A.4    Szegedi, S.S.5    Lestage, J.6    Castanon, N.7    Kelley, K.W.8    Dantzer, R.9
  • 36
    • 84894059828 scopus 로고    scopus 로고
    • Interleukin-18 deficiency and its long-term behavioural and cognitive impacts in a murine model of pneumococcal meningitis
    • Too, L.K.; Mitchell, A.J.; Yau, B.; Ball, H.J.; McGregor, I.S.; Hunt, N.H. Interleukin-18 deficiency and its long-term behavioural and cognitive impacts in a murine model of pneumococcal meningitis. Behav. Brain Res. 2014, 263, 176-189.
    • (2014) Behav. Brain Res , vol.263 , pp. 176-189
    • Too, L.K.1    Mitchell, A.J.2    Yau, B.3    Ball, H.J.4    McGregor, I.S.5    Hunt, N.H.6
  • 37
    • 79954598830 scopus 로고    scopus 로고
    • Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression
    • Maes, M. Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35, 664-175.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 175-664
    • Maes, M.1
  • 38
    • 77950022119 scopus 로고    scopus 로고
    • CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: Relationship to CNS immune responses and depression
    • Raison, C.L.; Dantzer, R.; Kelley, K.W.; Lawson, M.A.; Woolwine, B.J.; Vogt, G.; Spivey, J.R.; Saito, K.; Miller, A.H. CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: Relationship to CNS immune responses and depression. Mol. Psychiatry 2010, 15, 393-403.
    • (2010) Mol. Psychiatry , vol.15 , pp. 393-403
    • Raison, C.L.1    Dantzer, R.2    Kelley, K.W.3    Lawson, M.A.4    Woolwine, B.J.5    Vogt, G.6    Spivey, J.R.7    Saito, K.8    Miller, A.H.9
  • 40
    • 84876079221 scopus 로고    scopus 로고
    • Cytokine targets in the brain: Impact on neurotransmitters and neurocircuits
    • Miller, A.H.; Haroon, E.; Raison, C.L.; Felger, J.C. Cytokine targets in the brain: Impact on neurotransmitters and neurocircuits. Depress. Anxiety 2013, 30, 297-306.
    • (2013) Depress. Anxiety , vol.30 , pp. 297-306
    • Miller, A.H.1    Haroon, E.2    Raison, C.L.3    Felger, J.C.4
  • 42
    • 0014603015 scopus 로고
    • Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats
    • Chrusciel, M. Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats. Eur. J. Pharmacol. 1969, 8, 192-199.
    • (1969) Eur. J. Pharmacol , vol.8 , pp. 192-199
    • Chrusciel, M.1
  • 43
    • 84908609801 scopus 로고    scopus 로고
    • Insights from interferon-α-related depression for the pathogenesis of depression associated with inflammation
    • Hoyo-Becerra, C.; Schlaak, J.F.; Hermann, D.M. Insights from interferon-α-related depression for the pathogenesis of depression associated with inflammation. Brain Behav. Immun. 2014, 42, 222-231.
    • (2014) Brain Behav. Immun , vol.42 , pp. 222-231
    • Hoyo-Becerra, C.1    Schlaak, J.F.2    Hermann, D.M.3
  • 44
    • 77949809383 scopus 로고    scopus 로고
    • Simultaneous determination of serum tryptophan metabolites in patients with systemic lupus erythematosus by high performance liquid chromatography with fluorescence detection
    • Xiang, Z.Y.; Tang, A.G.; Ren, Y.P.; Zhou, Q.X.; Luo, X.B. Simultaneous determination of serum tryptophan metabolites in patients with systemic lupus erythematosus by high performance liquid chromatography with fluorescence detection. Clin. Chem. Lab. Med. 2010, 48, 513-517.
    • (2010) Clin. Chem. Lab. Med , vol.48 , pp. 513-517
    • Xiang, Z.Y.1    Tang, A.G.2    Ren, Y.P.3    Zhou, Q.X.4    Luo, X.B.5
  • 45
    • 0019967973 scopus 로고
    • An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid
    • Perkins, M.N.; Stone, T.W. An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 1982, 247, 184-187.
    • (1982) Brain Res , vol.247 , pp. 184-187
    • Perkins, M.N.1    Stone, T.W.2
  • 46
    • 0020545157 scopus 로고
    • Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system
    • Perkins, M.N.; Stone, T.W. Pharmacology and regional variations of quinolinic acid-evoked excitations in the rat central nervous system. J. Pharmacol. Exp. Ther. 1983, 226, 551-557.
    • (1983) J. Pharmacol. Exp. Ther , vol.226 , pp. 551-557
    • Perkins, M.N.1    Stone, T.W.2
  • 47
    • 0030272509 scopus 로고    scopus 로고
    • Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation
    • Hughes, P.E.; Alexi, T.; Yoshida, T.; Schreiber, S.S.; Knusel, B. Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas showing DNA fragmentation. Neuroscience 1996, 74, 1143-1160.
    • (1996) Neuroscience , vol.74 , pp. 1143-1160
    • Hughes, P.E.1    Alexi, T.2    Yoshida, T.3    Schreiber, S.S.4    Knusel, B.5
  • 50
    • 84925702647 scopus 로고    scopus 로고
    • Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression
    • Dantzer, R.; Walker, A.K. Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression? J. Neural Transm. 2014, 121, 925-932.
    • (2014) J. Neural Transm , vol.121 , pp. 925-932
    • Dantzer, R.1    Walker, A.K.2
  • 51
    • 0032051772 scopus 로고    scopus 로고
    • Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task
    • Shear, D.A.; Dong, J.; Haik-Creguer, K.L.; Bazzett, T.J.; Albin, R.L.; Dunbar, G.L. Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task. Exp. Neurol. 1998, 150, 305-311.
    • (1998) Exp. Neurol , vol.150 , pp. 305-311
    • Shear, D.A.1    Dong, J.2    Haik-Creguer, K.L.3    Bazzett, T.J.4    Albin, R.L.5    Dunbar, G.L.6
  • 53
    • 81155157520 scopus 로고    scopus 로고
    • Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission
    • Steiner, J.; Walter, M.; Gos, T.; Guillemin, G.J.; Bernstein, H.G.; Sarnyai, Z.; Mawrin, C.; Brisch, R.; Bielau, H.; Meyerzu Schwabedissen, L.; et al. Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission? J. Neuroinflamm. 2011, 8, 94.
    • (2011) J. Neuroinflamm , vol.8 , pp. 94
    • Steiner, J.1    Walter, M.2    Gos, T.3    Guillemin, G.J.4    Bernstein, H.G.5    Sarnyai, Z.6    Mawrin, C.7    Brisch, R.8    Bielau, H.9    Meyerzu Schwabedissen, L.10
  • 54
    • 0019440926 scopus 로고
    • Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS
    • Stone, T.W.; Perkins, M.N. Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS. Eur. J. Pharmacol. 1981, 72, 411-412.
    • (1981) Eur. J. Pharmacol , vol.72 , pp. 411-412
    • Stone, T.W.1    Perkins, M.N.2
  • 55
    • 0020591879 scopus 로고
    • Differential vulnerability of central neurons of the rat to quinolinic acid
    • Schwarcz, R.; Kohler, C. Differential vulnerability of central neurons of the rat to quinolinic acid. Neurosci. Lett. 1983, 38, 85-90.
    • (1983) Neurosci. Lett , vol.38 , pp. 85-90
    • Schwarcz, R.1    Kohler, C.2
  • 58
    • 70350022338 scopus 로고    scopus 로고
    • Pathogenesis of neuropsychiatric systemic lupus erythematosus and potential biomarkers
    • Efthimiou, P.; Blanco, M. Pathogenesis of neuropsychiatric systemic lupus erythematosus and potential biomarkers. Mod. Rheumatol. 2009, 19, 457-468.
    • (2009) Mod. Rheumatol , vol.19 , pp. 457-468
    • Efthimiou, P.1    Blanco, M.2
  • 60
    • 15744365822 scopus 로고    scopus 로고
    • Behavioral effects of infection with interferon-γ adenovector
    • Kwant, A.; Sakic, B. Behavioral effects of infection with interferon-γ adenovector. Behav. Brain Res. 2004, 151, 73-82.
    • (2004) Behav. Brain Res , vol.151 , pp. 73-82
    • Kwant, A.1    Sakic, B.2
  • 61
    • 0031818233 scopus 로고    scopus 로고
    • Attenuation of behavioral abnormalities in autoimmune mice by chronic soluble interferon-γ receptor treatment
    • Schrott, L.M.; Crnic, L.S. Attenuation of behavioral abnormalities in autoimmune mice by chronic soluble interferon-γ receptor treatment. Brain Behav. Immun. 1998, 12, 90-106.
    • (1998) Brain Behav. Immun , vol.12 , pp. 90-106
    • Schrott, L.M.1    Crnic, L.S.2
  • 68
    • 84922065273 scopus 로고    scopus 로고
    • Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity
    • Talaat, R.M.; Mohamed, S.F.; Bassyouni, I.H.; Raouf, A.A. Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity. Cytokine 2015, 72, 146-153.
    • (2015) Cytokine , vol.72 , pp. 146-153
    • Talaat, R.M.1    Mohamed, S.F.2    Bassyouni, I.H.3    Raouf, A.A.4
  • 69
    • 84936858065 scopus 로고    scopus 로고
    • Interferon-γ-Inducible chemokines in Systemic Lupus Erythematosus
    • Elia, G. Interferon-γ-Inducible chemokines in Systemic Lupus Erythematosus. Clin. Ther. 2015, 166, e41-e46.
    • (2015) Clin. Ther , vol.166 , pp. e41-e46
    • Elia, G.1
  • 70
    • 61849179867 scopus 로고    scopus 로고
    • Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus
    • Kong, K.O.; Tan, A.W.; Thong, B.Y.; Lian, T.Y.; Cheng, Y.K.; Teh, C.L.; Koh, E.T.; Chng, H.H.; Law, W.G.; Lau, T.C.; et al. Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus. Clin. Exp. Immunol. 2009, 156, 134-140.
    • (2009) Clin. Exp. Immunol , vol.156 , pp. 134-140
    • Kong, K.O.1    Tan, A.W.2    Thong, B.Y.3    Lian, T.Y.4    Cheng, Y.K.5    Teh, C.L.6    Koh, E.T.7    Chng, H.H.8    Law, W.G.9    Lau, T.C.10
  • 71
    • 77951250725 scopus 로고    scopus 로고
    • Intrathecal cytokine and chemokine profiling in neuropsychiatric lupus or lupus complicated with central nervous system infection
    • Lu, X.Y.; Zhu, C.Q.; Qian, J.; Chen, X.X.; Ye, S.; Gu, Y.Y. Intrathecal cytokine and chemokine profiling in neuropsychiatric lupus or lupus complicated with central nervous system infection. Lupus 2010, 19, 689-695.
    • (2010) Lupus , vol.19 , pp. 689-695
    • Lu, X.Y.1    Zhu, C.Q.2    Qian, J.3    Chen, X.X.4    Ye, S.5    Gu, Y.Y.6
  • 72
    • 31544449201 scopus 로고    scopus 로고
    • IP-10/MCP-1 ratio in CSF is an useful diagnostic marker of neuropsychiatric lupus patients
    • Okamoto, H.; Iikuni, N.; Kamitsuji, S.; Yoshio, T.; Minota, S.; Kamatani, N. IP-10/MCP-1 ratio in CSF is an useful diagnostic marker of neuropsychiatric lupus patients. Rheumatology 2006, 45, 232-234.
    • (2006) Rheumatology , vol.45 , pp. 232-234
    • Okamoto, H.1    Iikuni, N.2    Kamitsuji, S.3    Yoshio, T.4    Minota, S.5    Kamatani, N.6
  • 73
    • 60549087405 scopus 로고    scopus 로고
    • Potent induction of IFN-α and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus
    • Santer, D.M.; Yoshio, T.; Minota, S.; Moller, T.; Elkon, K.B. Potent induction of IFN-α and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus. J. Immunol. 2009, 182, 1192-1201.
    • (2009) J. Immunol , vol.182 , pp. 1192-1201
    • Santer, D.M.1    Yoshio, T.2    Minota, S.3    Moller, T.4    Elkon, K.B.5
  • 75
    • 84929754369 scopus 로고    scopus 로고
    • Pentraxin 3 as a biomarker of local inflammatory response to vascular injury in systemic lupus erythematosus
    • Cieslik, P.; Hrycek, A. Pentraxin 3 as a biomarker of local inflammatory response to vascular injury in systemic lupus erythematosus. Autoimmunity 2014, 48, 1-9.
    • (2014) Autoimmunity , vol.48 , pp. 1-9
    • Cieslik, P.1    Hrycek, A.2
  • 77
    • 79960844662 scopus 로고    scopus 로고
    • Interaction between oxidative stress and chemokines: Possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis
    • Shah, D.; Wanchu, A.; Bhatnagar, A. Interaction between oxidative stress and chemokines: Possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis. Immunobiology 2011, 216, 1010-1017.
    • (2011) Immunobiology , vol.216 , pp. 1010-1017
    • Shah, D.1    Wanchu, A.2    Bhatnagar, A.3
  • 79
    • 0347814978 scopus 로고    scopus 로고
    • Increased ICAM-1 and VCAM-1 expression in the brains of autoimmune mice
    • Zameer, A.; Hoffman, S.A. Increased ICAM-1 and VCAM-1 expression in the brains of autoimmune mice. J. Neuroimmunol. 2003, 142, 67-74.
    • (2003) J. Neuroimmunol , vol.142 , pp. 67-74
    • Zameer, A.1    Hoffman, S.A.2
  • 80
    • 37549072994 scopus 로고    scopus 로고
    • Proteomic analysis of plasma from patients with systemic lupus erythematosus: Increased presence of haptoglobin α2 polypeptide chains over the α1 isoforms
    • Pavon, E.J.; Munoz, P.; Lario, A.; Longobardo, V.; Carrascal, M.; Abian, J.; Martin, A.B.; Arias, S.A.; Callejas-Rubio, J.L.; Sola, R.; et al. Proteomic analysis of plasma from patients with systemic lupus erythematosus: Increased presence of haptoglobin α2 polypeptide chains over the α1 isoforms. Proteomics 2006, 6, S282-S292.
    • (2006) Proteomics , vol.6 , pp. S282-S292
    • Pavon, E.J.1    Munoz, P.2    Lario, A.3    Longobardo, V.4    Carrascal, M.5    Abian, J.6    Martin, A.B.7    Arias, S.A.8    Callejas-Rubio, J.L.9    Sola, R.10
  • 82
    • 0023508160 scopus 로고
    • Fibroblast growth factor: Structural and biological properties
    • Gospodarowicz, D.; Neufeld, G.; Schweigerer, L. Fibroblast growth factor: Structural and biological properties. J. Cell. Physiol. 1987, 5, 15-26.
    • (1987) J. Cell. Physiol , vol.5 , pp. 15-26
    • Gospodarowicz, D.1    Neufeld, G.2    Schweigerer, L.3
  • 83
    • 0023814706 scopus 로고
    • Increased basic fibroblast growth factor (BFGF) immunoreactivity at the site of focal brain wounds
    • Finklestein, S.P.; Apostolides, P.J.; Caday, C.G.; Prosser, J.; Philips, M.F.; Klagsbrun, M. Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds. Brain Res. 1988, 460, 253-259.
    • (1988) Brain Res , vol.460 , pp. 253-259
    • Finklestein, S.P.1    Apostolides, P.J.2    Caday, C.G.3    Prosser, J.4    Philips, M.F.5    Klagsbrun, M.6
  • 84
    • 0346157995 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of fibroblast growth factor-2 protects against myocardial dysfunction and infarction in a murine model of low-flow ischemia
    • House, S.L.; Bolte, C.; Zhou, M.; Doetschman, T.; Klevitsky, R.; Newman, G.; Schultz Jel, J. Cardiac-specific overexpression of fibroblast growth factor-2 protects against myocardial dysfunction and infarction in a murine model of low-flow ischemia. Circulation 2003, 108, 3140-3148.
    • (2003) Circulation , vol.108 , pp. 3140-3148
    • House, S.L.1    Bolte, C.2    Zhou, M.3    Doetschman, T.4    Klevitsky, R.5    Newman, G.6    Schultz Jel, J.7
  • 85
    • 0023139994 scopus 로고
    • Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth
    • Schweigerer, L.; Neufeld, G.; Friedman, J.; Abraham, J.A.; Fiddes, J.C.; Gospodarowicz, D. Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. Nature 1987, 325, 257-259.
    • (1987) Nature , vol.325 , pp. 257-259
    • Schweigerer, L.1    Neufeld, G.2    Friedman, J.3    Abraham, J.A.4    Fiddes, J.C.5    Gospodarowicz, D.6
  • 86
    • 0023203020 scopus 로고
    • Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures
    • Carlin, J.M.; Borden, E.C.; Sondel, P.M.; Byrne, G.I. Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures. J. Immunol. 1987, 139, 2414-2418.
    • (1987) J. Immunol , vol.139 , pp. 2414-2418
    • Carlin, J.M.1    Borden, E.C.2    Sondel, P.M.3    Byrne, G.I.4
  • 87
    • 0000273861 scopus 로고
    • Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: Its possible occurrence in cancer patients
    • Yasui, H.; Takai, K.; Yoshida, R.; Hayaishi, O. Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: Its possible occurrence in cancer patients. Proc. Natl. Acad. Sci. USA 1986, 83, 6622-6626.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6622-6626
    • Yasui, H.1    Takai, K.2    Yoshida, R.3    Hayaishi, O.4
  • 88
    • 79954604454 scopus 로고    scopus 로고
    • The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
    • Maes, M.; Leonard, B.E.; Myint, A.M.; Kubera, M.; Verkerk, R. The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35, 702-721.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 702-721
    • Maes, M.1    Leonard, B.E.2    Myint, A.M.3    Kubera, M.4    Verkerk, R.5
  • 90
    • 66549102581 scopus 로고    scopus 로고
    • Co-operative action of interleukin-10 and interferon-γ to regulate dendritic cell functions
    • Yanagawa, Y.; Iwabuchi, K.; Onoe, K. Co-operative action of interleukin-10 and interferon-γ to regulate dendritic cell functions. Immunology 2009, 127, 345-353.
    • (2009) Immunology , vol.127 , pp. 345-353
    • Yanagawa, Y.1    Iwabuchi, K.2    Onoe, K.3
  • 93
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor, A.L.; Munn, D.H. IDO expression by dendritic cells: Tolerance and tryptophan catabolism. Nat. Rev. Immunol. 2004, 4, 762-774.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 94
    • 34248335693 scopus 로고    scopus 로고
    • Elevations of endogenous kynurenic acid produce spatial working memory deficits
    • Chess, A.C.; Simoni, M.K.; Alling, T.E.; Bucci, D.J. Elevations of endogenous kynurenic acid produce spatial working memory deficits. Schizophr. Bull. 2007, 33, 797-804.
    • (2007) Schizophr. Bull , vol.33 , pp. 797-804
    • Chess, A.C.1    Simoni, M.K.2    Alling, T.E.3    Bucci, D.J.4
  • 97
    • 33745712943 scopus 로고    scopus 로고
    • Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury
    • Dimitrijevic, O.B.; Stamatovic, S.M.; Keep, R.F.; Andjelkovic, A.V. Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury. J. Cereb. Blood Flow Metab. 2006, 26, 797-810.
    • (2006) J. Cereb. Blood Flow Metab , vol.26 , pp. 797-810
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 98
    • 84919459586 scopus 로고    scopus 로고
    • Expression of neuronal CXCL10 induced by rabies virus infection initiates infiltration of inflammatory cells, production of chemokines and cytokines, and enhancement of blood-brain barrier permeability
    • Chai, Q.; She, R.; Huang, Y.; Fu, Z.F. Expression of neuronal CXCL10 induced by rabies virus infection initiates infiltration of inflammatory cells, production of chemokines and cytokines, and enhancement of blood-brain barrier permeability. J. Virol. 2015, 89, 870-876.
    • (2015) J. Virol , vol.89 , pp. 870-876
    • Chai, Q.1    She, R.2    Huang, Y.3    Fu, Z.F.4
  • 99
    • 38849193303 scopus 로고    scopus 로고
    • Biomarkers of HIV related central nervous system disease
    • Brew, B.J.; Letendre, S.L. Biomarkers of HIV related central nervous system disease. Int. Rev. Psychiatry 2008, 20, 73-88.
    • (2008) Int. Rev. Psychiatry , vol.20 , pp. 73-88
    • Brew, B.J.1    Letendre, S.L.2
  • 100
    • 84856383137 scopus 로고    scopus 로고
    • CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer’s disease
    • Westin, K.; Buchhave, P.; Nielsen, H.; Minthon, L.; Janciauskiene, S.; Hansson, O. CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer’s disease. PLoS ONE 2012, 7, e30525.
    • (2012) Plos ONE , vol.7
    • Westin, K.1    Buchhave, P.2    Nielsen, H.3    Minthon, L.4    Janciauskiene, S.5    Hansson, O.6
  • 101
    • 0035010218 scopus 로고    scopus 로고
    • Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid
    • Chiarugi, A.; Meli, E.; Moroni, F. Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid. J. Neurochem. 2001, 77, 1310-1318.
    • (2001) J. Neurochem , vol.77 , pp. 1310-1318
    • Chiarugi, A.1    Meli, E.2    Moroni, F.3
  • 102
    • 0025672787 scopus 로고
    • The role of hydrogen peroxide in the in vitro cytotoxicity of 3-hydroxykynurenine
    • Eastman, C.L.; Guilarte, T.R. The role of hydrogen peroxide in the in vitro cytotoxicity of 3-hydroxykynurenine. Neurochem. Res. 1990, 15, 1101-1107.
    • (1990) Neurochem. Res , vol.15 , pp. 1101-1107
    • Eastman, C.L.1    Guilarte, T.R.2
  • 103
    • 0031972945 scopus 로고    scopus 로고
    • 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity
    • Okuda, S.; Nishiyama, N.; Saito, H.; Katsuki, H. 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity. J. Neurochem. 1998, 70, 299-307.
    • (1998) J. Neurochem , vol.70 , pp. 299-307
    • Okuda, S.1    Nishiyama, N.2    Saito, H.3    Katsuki, H.4
  • 104
    • 84874067165 scopus 로고    scopus 로고
    • Kynurenines in cognitive functions: Their possible role in depression
    • Plangar, I.; Majlath, Z.; Vecsei, L. Kynurenines in cognitive functions: Their possible role in depression. Neuropsychopharmacol. Hung. 2012, 14, 239-244.
    • (2012) Neuropsychopharmacol. Hung , vol.14 , pp. 239-244
    • Plangar, I.1    Majlath, Z.2    Vecsei, L.3
  • 107
    • 0026458258 scopus 로고
    • A new one-trial test for neurobiological studies of memory in rats. III. Spatial vs. Non-spatial working memory
    • Ennaceur, A.; Meliani, K. A new one-trial test for neurobiological studies of memory in rats. III. Spatial vs. non-spatial working memory. Behav. Brain Res. 1992, 51, 83-92.
    • (1992) Behav. Brain Res , vol.51 , pp. 83-92
    • Ennaceur, A.1    Meliani, K.2
  • 108
    • 77249178279 scopus 로고    scopus 로고
    • Lesions of the rat perirhinal cortex spare the acquisition of a complex configural visual discrimination yet impair object recognition
    • Aggleton, J.P.; Albasser, M.M.; Aggleton, D.J.; Poirier, G.L.; Pearce, J.M. Lesions of the rat perirhinal cortex spare the acquisition of a complex configural visual discrimination yet impair object recognition. Behav. Neurosci. 2010, 124, 55-68.
    • (2010) Behav. Neurosci , vol.124 , pp. 55-68
    • Aggleton, J.P.1    Albasser, M.M.2    Aggleton, D.J.3    Poirier, G.L.4    Pearce, J.M.5
  • 109
    • 60549094597 scopus 로고    scopus 로고
    • Magnitude of the object recognition deficit associated with perirhinal cortex damage in rats: Effects of varying the lesion extent and the duration of the sample period
    • Albasser, M.M.; Davies, M.; Futter, J.E.; Aggleton, J.P. Magnitude of the object recognition deficit associated with perirhinal cortex damage in rats: Effects of varying the lesion extent and the duration of the sample period. Behav. Neurosci. 2009, 123, 115-124.
    • (2009) Behav. Neurosci , vol.123 , pp. 115-124
    • Albasser, M.M.1    Davies, M.2    Futter, J.E.3    Aggleton, J.P.4
  • 110
    • 84856078575 scopus 로고    scopus 로고
    • TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
    • Belarbi, K.; Jopson, T.; Tweedie, D.; Arellano, C.; Luo, W.; Greig, N.H.; Rosi, S. TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation. J. Neuroinflamm. 2012, 9, 23.
    • (2012) J. Neuroinflamm , vol.9 , pp. 23
    • Belarbi, K.1    Jopson, T.2    Tweedie, D.3    Arellano, C.4    Luo, W.5    Greig, N.H.6    Rosi, S.7
  • 111
    • 84919832455 scopus 로고    scopus 로고
    • Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)
    • Chitu, V.; Gokhan, S.; Gulinello, M.; Branch, C.A.; Patil, M.; Basu, R.; Stoddart, C.; Mehler, M.F.; Stanley, E.R. Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP). Neurobiol. Dis. 2015, 74, 219-228.
    • (2015) Neurobiol. Dis , vol.74 , pp. 219-228
    • Chitu, V.1    Gokhan, S.2    Gulinello, M.3    Branch, C.A.4    Patil, M.5    Basu, R.6    Stoddart, C.7    Mehler, M.F.8    Stanley, E.R.9
  • 113
    • 77952544767 scopus 로고    scopus 로고
    • Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine
    • Li, Y.; Vijayanathan, V.; Gulinello, M.; Cole, P.D. Intrathecal methotrexate induces focal cognitive deficits and increases cerebrospinal fluid homocysteine. Pharmacol. Biochem. Behav. 2010, 95, 428-433.
    • (2010) Pharmacol. Biochem. Behav , vol.95 , pp. 428-433
    • Li, Y.1    Vijayanathan, V.2    Gulinello, M.3    Cole, P.D.4
  • 114
    • 72149134895 scopus 로고    scopus 로고
    • Systemic methotrexate induces spatial memory deficits and depletes cerebrospinal fluid folate in rats
    • Li, Y.; Vijayanathan, V.; Gulinello, M.E.; Cole, P.D. Systemic methotrexate induces spatial memory deficits and depletes cerebrospinal fluid folate in rats. Pharmacol. Biochem. Behav. 2010, 94, 454-463.
    • (2010) Pharmacol. Biochem. Behav , vol.94 , pp. 454-463
    • Li, Y.1    Vijayanathan, V.2    Gulinello, M.E.3    Cole, P.D.4
  • 115
    • 80052970915 scopus 로고    scopus 로고
    • Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist
    • Vijayanathan, V.; Gulinello, M.; Ali, N.; Cole, P.D. Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be reversed by an NMDA antagonist. Behav. Brain Res. 2011, 225, 491-497.
    • (2011) Behav. Brain Res , vol.225 , pp. 491-497
    • Vijayanathan, V.1    Gulinello, M.2    Ali, N.3    Cole, P.D.4
  • 116
    • 0023691166 scopus 로고
    • A new one-trial test for neurobiological studies of memory in rats. 1
    • Ennaceur, A.; Delacour, J. A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. Behav. Brain Res. 1988, 31, 47-59.
    • (1988) Behavioral Data. Behav. Brain Res , vol.31 , pp. 47-59
    • Ennaceur, A.1    Delacour, J.2
  • 117
    • 0024494969 scopus 로고
    • A comparison of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety
    • Bodnoff, S.R.; Suranyi-Cadotte, B.; Quirion, R.; Meaney, M.J. A comparison of the effects of diazepam versus several typical and atypical anti-depressant drugs in an animal model of anxiety. Psychopharmacology 1989, 97, 277-279.
    • (1989) Psychopharmacology , vol.97 , pp. 277-279
    • Bodnoff, S.R.1    Suranyi-Cadotte, B.2    Quirion, R.3    Meaney, M.J.4
  • 118
    • 0022620470 scopus 로고
    • Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat
    • Pellow, S.; File, S.E. Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat. Pharmacol. Biochem. Behav. 1986, 24, 525-529.
    • (1986) Pharmacol. Biochem. Behav , vol.24 , pp. 525-529
    • Pellow, S.1    File, S.E.2
  • 119
    • 0018763594 scopus 로고
    • Animal model of depression
    • Porsolt, R.D. Animal model of depression. Biomedicine 1979, 30, 139-140.
    • (1979) Biomedicine , vol.30 , pp. 139-140
    • Porsolt, R.D.1
  • 120
    • 0018196837 scopus 로고
    • Behavioural despair in rats and mice: Strain differences and the effects of imipramine
    • Porsolt, R.D.; Bertin, A.; Jalfre, M. “Behavioural despair” in rats and mice: Strain differences and the effects of imipramine. Eur. J. Pharmacol. 1978, 51, 291-294.
    • (1978) Eur. J. Pharmacol , vol.51 , pp. 291-294
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3


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