Deletion of the PH-domain and leucine-rich repeat protein phosphatase 1 (Phlpp1) increases fibroblast growth factor (Fgf) 18 expression and promotes chondrocyte proliferation

Journal of Biological Chemistry

Volumn 290, Issue 26, 2015, Pages 16272-16280

  Bradley, Elizabeth W ^a   Carpio, Lomeli R ^a   Newton, Alexandra C ^a   Westendorf, Jennifer J ^a,b  

^a MAYO CLINIC   (United States)

^b University of California San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BODY FLUIDS; BONE; CELL CULTURE; METABOLISM; MUSCULOSKELETAL SYSTEM; PHOSPHATASES; PHOSPHORYLATION; PROTEINS; REPAIR;

CARTILAGE REGENERATION; CHEMICAL INHIBITION; CHONDROCYTE PROLIFERATION; ENDOCHONDRAL OSSIFICATION; FIBROBLAST GROWTH FACTOR; LEUCINE-RICH REPEATS; METABOLIC ACTIVITY; PROTEIN PHOSPHATASE;

CARTILAGE;

FIBROBLAST GROWTH FACTOR 18; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE B BETA; PROTEIN PHLPP1; S6 KINASE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; NUCLEAR PROTEIN; PHLPP PROTEIN, MOUSE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; BONE LENGTH; BONE MASS; BONE MATRIX; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL METABOLISM; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; ANIMAL; CARTILAGE; CYTOLOGY; GENE DELETION; GENETICS; KNOCKOUT MOUSE; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; CARTILAGE; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; FIBROBLAST GROWTH FACTORS; FORKHEAD TRANSCRIPTION FACTORS; GENE DELETION; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84936814648     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.612937     Document Type: Article

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