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Volumn 15, Issue 8, 2014, Pages 13236-13246

Disruption of phosphoinositide-specific phospholipases Cγ1 contributes to extracellular matrix synthesis of human osteoarthritis chondrocytes

Author keywords

ECM; Human OA chondrocytes; PLC 1

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; PHOSPHOLIPASE C GAMMA; S6 KINASE; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR SOX9;

EID: 84905182019     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150813236     Document Type: Article
Times cited : (25)

References (26)
  • 1
    • 84884239861 scopus 로고    scopus 로고
    • The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis
    • doi:10.1155/2013/284873
    • Maldonado, M.; Nam, J. The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. Biomed. Res. Int. 2013, doi:10.1155/2013/284873.
    • (2013) Biomed. Res. Int.
    • Maldonado, M.1    Nam, J.2
  • 3
    • 65249119818 scopus 로고    scopus 로고
    • Adaptor proteins and Ras synergistically regulate IL-1-induced ADAMTS-4 expression in human chondrocytes
    • Ahmad, R.; Sylvester, J.; Ahmad, M.; Zafarullah, M. Adaptor proteins and Ras synergistically regulate IL-1-induced ADAMTS-4 expression in human chondrocytes. J. Immunol. 2009, 182, 5081-5087.
    • (2009) J. Immunol. , vol.182 , pp. 5081-5087
    • Ahmad, R.1    Sylvester, J.2    Ahmad, M.3    Zafarullah, M.4
  • 4
    • 0034927336 scopus 로고    scopus 로고
    • Regulation of phosphoinositide-specific phospholipase C
    • Rhee, S.G. Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem. 2001, 70, 281-312.
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 281-312
    • Rhee, S.G.1
  • 5
    • 14644397216 scopus 로고    scopus 로고
    • Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion
    • Tvorogov, D.; Wang, X.J.; Zent, R.; Carpenter, G. Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion. J. Cell Sci. 2005, 118, 601-610.
    • (2005) J. Cell Sci. , vol.118 , pp. 601-610
    • Tvorogov, D.1    Wang, X.J.2    Zent, R.3    Carpenter, G.4
  • 7
    • 77953749904 scopus 로고    scopus 로고
    • U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism
    • Burgdorf, C.; Schäfer, U.; Richardt, G.; Kurz, T. U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism. J. Cardiovasc. Pharmacol. 2010, 55, 555-559.
    • (2010) J. Cardiovasc. Pharmacol. , vol.55 , pp. 555-559
    • Burgdorf, C.1    Schäfer, U.2    Richardt, G.3    Kurz, T.4
  • 8
    • 34347259534 scopus 로고    scopus 로고
    • Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1
    • Harada, D.; Yamanaka, Y.; Ueda, K.; Nishimura, R.; Morishima, T.; Seino, Y.; Tanaka, H. Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1. Bone 2007, 41, 273-281.
    • (2007) Bone , vol.41 , pp. 273-281
    • Harada, D.1    Yamanaka, Y.2    Ueda, K.3    Nishimura, R.4    Morishima, T.5    Seino, Y.6    Tanaka, H.7
  • 9
    • 84863237736 scopus 로고    scopus 로고
    • Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics
    • Biswas, S.; Manikandan, J.; Pushparaj, P.N. Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics. Bioinformation 2011, 6, 153-157.
    • (2011) Bioinformation , vol.6 , pp. 153-157
    • Biswas, S.1    Manikandan, J.2    Pushparaj, P.N.3
  • 10
    • 14744305948 scopus 로고    scopus 로고
    • Basic science of articular cartilage and osteoarthritis
    • Pearle, A.D.; Warren, R.F.; Rodeo, S.A. Basic science of articular cartilage and osteoarthritis. Clin. Sports Med. 2005, 24, 1-12.
    • (2005) Clin. Sports Med. , vol.24 , pp. 1-12
    • Pearle, A.D.1    Warren, R.F.2    Rodeo, S.A.3
  • 12
    • 80052705795 scopus 로고    scopus 로고
    • Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis
    • Nam, J.; Perera, P.; Liu, J.; Rath, B.; Deschner, J.; Gassner, R.; Butterfield, T.A.; Agarwal, S. Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. PLoS One 2011, 6, e24320.
    • (2011) PLoS One , vol.6
    • Nam, J.1    Perera, P.2    Liu, J.3    Rath, B.4    Deschner, J.5    Gassner, R.6    Butterfield, T.A.7    Agarwal, S.8
  • 13
    • 80755171253 scopus 로고    scopus 로고
    • SOX trio decrease in the articular cartilage with the advancement of osteoarthritis
    • Lee, J.S.; Im, G.I. SOX trio decrease in the articular cartilage with the advancement of osteoarthritis. Connect. Tissue Res. 2011, 52, 496-502.
    • (2011) Connect. Tissue Res. , vol.52 , pp. 496-502
    • Lee, J.S.1    Im, G.I.2
  • 14
    • 84872455053 scopus 로고    scopus 로고
    • Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression
    • Wang, Q.; Siminovitch, K.A.; Downey, G.P.; McCulloch, C.A. Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression. Biochem. J. 2013, 449, 771-782.
    • (2013) Biochem. J. , vol.449 , pp. 771-782
    • Wang, Q.1    Siminovitch, K.A.2    Downey, G.P.3    McCulloch, C.A.4
  • 15
    • 0036289135 scopus 로고    scopus 로고
    • Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3
    • Kanaki, T.; Bujo, H.; Mori, S.; Yanjuan, Z.; Takahashi, K.; Yokote, K.; Morisaki, N.; Saito, Y. Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3. Biochem. Biophys. Res. Commun. 2002, 294, 231-237.
    • (2002) Biochem. Biophys. Res. Commun. , vol.294 , pp. 231-237
    • Kanaki, T.1    Bujo, H.2    Mori, S.3    Yanjuan, Z.4    Takahashi, K.5    Yokote, K.6    Morisaki, N.7    Saito, Y.8
  • 16
    • 78651275140 scopus 로고    scopus 로고
    • Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis
    • Yuan, F.L.; Chen, F.H.; Lu, W.G.; Li, X.; Li, J.P.; Li, C.W.; Xu, R.S.; Wu, F.R.; Hu, W.; Zhang, T.Y.; et al. Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis. Inflamm. Res. 2010, 59, 939-947.
    • (2010) Inflamm. Res. , vol.59 , pp. 939-947
    • Yuan, F.L.1    Chen, F.H.2    Lu, W.G.3    Li, X.4    Li, J.P.5    Li, C.W.6    Xu, R.S.7    Wu, F.R.8    Hu, W.9    Zhang, T.Y.10
  • 17
    • 84866444898 scopus 로고    scopus 로고
    • Intracellular calcium oscillations in articular chondrocytes induced by basic calcium phosphate crystals lead to cartilage degradation
    • Nguyen, C.; Lieberherr, M.; Bordat, C.; Velard, F.; Côme, D.; Lioté, F.; Ea, H.K. Intracellular calcium oscillations in articular chondrocytes induced by basic calcium phosphate crystals lead to cartilage degradation. Osteoarthr. Cartil. 2012, 20, 1399-1408.
    • (2012) Osteoarthr. Cartil. , vol.20 , pp. 1399-1408
    • Nguyen, C.1    Lieberherr, M.2    Bordat, C.3    Velard, F.4    Côme, D.5    Lioté, F.6    Ea, H.K.7
  • 19
    • 16844366670 scopus 로고    scopus 로고
    • ABL oncogenes and phosphoinositide 3-kinase: Mechanism of activation and downstream effectors
    • Kharas, M.G.; Fruman, D.A. ABL oncogenes and phosphoinositide 3-kinase: Mechanism of activation and downstream effectors. Cancer Res. 2005, 65, 2047-2053.
    • (2005) Cancer Res. , vol.65 , pp. 2047-2053
    • Kharas, M.G.1    Fruman, D.A.2
  • 20
    • 0036320205 scopus 로고    scopus 로고
    • Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
    • Edinger, A.L.; Thompson, C.B. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol. Biol. Cell. 2002, 13, 2276-2288.
    • (2002) Mol. Biol. Cell. , vol.13 , pp. 2276-2288
    • Edinger, A.L.1    Thompson, C.B.2
  • 21
    • 84890303026 scopus 로고    scopus 로고
    • Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D
    • doi:10.1186/1478-811X-11-3
    • Razmara, M.; Heldin, C.H.; Lennartsson, J. Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D. Cell. Commun. Signal. 2013, 11, doi:10.1186/1478-811X-11-3.
    • (2013) Cell. Commun. Signal. , vol.11
    • Razmara, M.1    Heldin, C.H.2    Lennartsson, J.3
  • 23
    • 84857014229 scopus 로고    scopus 로고
    • Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia
    • Zhang, T.; Lu, X.; Li, J.; Chidiac, P.; Sims, S.M.; Feng, Q. Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia. Basic Res. Cardiol. 2012, 107, 1435-1803.
    • (2012) Basic Res. Cardiol. , vol.107 , pp. 1435-1803
    • Zhang, T.1    Lu, X.2    Li, J.3    Chidiac, P.4    Sims, S.M.5    Feng, Q.6
  • 24
    • 0034704070 scopus 로고    scopus 로고
    • Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor. Potential for pharmacological intervention
    • Attur, M.G.; Dave, M.; Cipolletta, C.; Kang, P.; Goldring, M.B.; Patel, I.R.; Abramson, S.B.; Amin, A.R. Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor. Potential for pharmacological intervention. J. Biol. Chem. 2000, 275, 40307-40315.
    • (2000) J. Biol. Chem. , vol.275 , pp. 40307-40315
    • Attur, M.G.1    Dave, M.2    Cipolletta, C.3    Kang, P.4    Goldring, M.B.5    Patel, I.R.6    Abramson, S.B.7    Amin, A.R.8
  • 25
    • 84860277806 scopus 로고    scopus 로고
    • Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Ca in chondrocytes
    • Chen, Q.; Zhang, B.; Yi, T.; Xia, C. Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Ca in chondrocytes. Folia Histochem. Cytobiol. 2012, 50, 137-143.
    • (2012) Folia Histochem. Cytobiol. , vol.50 , pp. 137-143
    • Chen, Q.1    Zhang, B.2    Yi, T.3    Xia, C.4
  • 26
    • 84855718266 scopus 로고    scopus 로고
    • 17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway
    • Huang, J.G.; Xia, C.; Zheng, X.P.; Yi, T.T.; Wang, X.Y.; Song, G.; Zhang, B. 17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway. Cell. Mol. Biol. Lett. 2011, 16, 564-575.
    • (2011) Cell. Mol. Biol. Lett. , vol.16 , pp. 564-575
    • Huang, J.G.1    Xia, C.2    Zheng, X.P.3    Yi, T.T.4    Wang, X.Y.5    Song, G.6    Zhang, B.7


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