-
1
-
-
84884239861
-
The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis
-
doi:10.1155/2013/284873
-
Maldonado, M.; Nam, J. The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. Biomed. Res. Int. 2013, doi:10.1155/2013/284873.
-
(2013)
Biomed. Res. Int.
-
-
Maldonado, M.1
Nam, J.2
-
2
-
-
61649117053
-
Activation of cartilage matrix metalloproteinases by activated protein C
-
Jackson, M.T.; Smith, M.M.; Smith, S.M.; Jackson, C.J.; Xue, M.; Little, C.B. Activation of cartilage matrix metalloproteinases by activated protein C. Arthritis Rheumatol. 2009, 60, 780-791.
-
(2009)
Arthritis Rheumatol.
, vol.60
, pp. 780-791
-
-
Jackson, M.T.1
Smith, M.M.2
Smith, S.M.3
Jackson, C.J.4
Xue, M.5
Little, C.B.6
-
3
-
-
65249119818
-
Adaptor proteins and Ras synergistically regulate IL-1-induced ADAMTS-4 expression in human chondrocytes
-
Ahmad, R.; Sylvester, J.; Ahmad, M.; Zafarullah, M. Adaptor proteins and Ras synergistically regulate IL-1-induced ADAMTS-4 expression in human chondrocytes. J. Immunol. 2009, 182, 5081-5087.
-
(2009)
J. Immunol.
, vol.182
, pp. 5081-5087
-
-
Ahmad, R.1
Sylvester, J.2
Ahmad, M.3
Zafarullah, M.4
-
4
-
-
0034927336
-
Regulation of phosphoinositide-specific phospholipase C
-
Rhee, S.G. Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem. 2001, 70, 281-312.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 281-312
-
-
Rhee, S.G.1
-
5
-
-
14644397216
-
Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion
-
Tvorogov, D.; Wang, X.J.; Zent, R.; Carpenter, G. Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion. J. Cell Sci. 2005, 118, 601-610.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 601-610
-
-
Tvorogov, D.1
Wang, X.J.2
Zent, R.3
Carpenter, G.4
-
6
-
-
84893769451
-
Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion
-
Timsah, Z.; Ahmed, Z.; Lin, C.C.; Melo, F.A.; Stagg, L.J.; Leonard, P.G.; Jeyabal, P.; Berrout, J.; O'Neil, R.G.; Bogdanov, M.; et al. Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion. Nat. Struct. Mol. Biol. 2014, 21, 180-188.
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 180-188
-
-
Timsah, Z.1
Ahmed, Z.2
Lin, C.C.3
Melo, F.A.4
Stagg, L.J.5
Leonard, P.G.6
Jeyabal, P.7
Berrout, J.8
O'Neil, R.G.9
Bogdanov, M.10
-
7
-
-
77953749904
-
U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism
-
Burgdorf, C.; Schäfer, U.; Richardt, G.; Kurz, T. U73122, an aminosteroid phospholipase C inhibitor, is a potent inhibitor of cardiac phospholipase D by a PIP2-dependent mechanism. J. Cardiovasc. Pharmacol. 2010, 55, 555-559.
-
(2010)
J. Cardiovasc. Pharmacol.
, vol.55
, pp. 555-559
-
-
Burgdorf, C.1
Schäfer, U.2
Richardt, G.3
Kurz, T.4
-
8
-
-
34347259534
-
Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1
-
Harada, D.; Yamanaka, Y.; Ueda, K.; Nishimura, R.; Morishima, T.; Seino, Y.; Tanaka, H. Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1. Bone 2007, 41, 273-281.
-
(2007)
Bone
, vol.41
, pp. 273-281
-
-
Harada, D.1
Yamanaka, Y.2
Ueda, K.3
Nishimura, R.4
Morishima, T.5
Seino, Y.6
Tanaka, H.7
-
9
-
-
84863237736
-
Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics
-
Biswas, S.; Manikandan, J.; Pushparaj, P.N. Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: A functional genomics paradigm to design disease specific therapeutics. Bioinformation 2011, 6, 153-157.
-
(2011)
Bioinformation
, vol.6
, pp. 153-157
-
-
Biswas, S.1
Manikandan, J.2
Pushparaj, P.N.3
-
10
-
-
14744305948
-
Basic science of articular cartilage and osteoarthritis
-
Pearle, A.D.; Warren, R.F.; Rodeo, S.A. Basic science of articular cartilage and osteoarthritis. Clin. Sports Med. 2005, 24, 1-12.
-
(2005)
Clin. Sports Med.
, vol.24
, pp. 1-12
-
-
Pearle, A.D.1
Warren, R.F.2
Rodeo, S.A.3
-
11
-
-
0030735269
-
Osteoarthritic lesions: Involvement of three different collagenases
-
Shlopov, B.V.; Lie, W.R.; Mainardi, C.L.; Cole, A.A.; Chubinskaya, S.; Hasty, K.A. Osteoarthritic lesions: involvement of three different collagenases. Arthritis Rheumatol. 1997, 40, 2065-2074.
-
(1997)
Arthritis Rheumatol.
, vol.40
, pp. 2065-2074
-
-
Shlopov, B.V.1
Lie, W.R.2
Mainardi, C.L.3
Cole, A.A.4
Chubinskaya, S.5
Hasty, K.A.6
-
12
-
-
80052705795
-
Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis
-
Nam, J.; Perera, P.; Liu, J.; Rath, B.; Deschner, J.; Gassner, R.; Butterfield, T.A.; Agarwal, S. Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. PLoS One 2011, 6, e24320.
-
(2011)
PLoS One
, vol.6
-
-
Nam, J.1
Perera, P.2
Liu, J.3
Rath, B.4
Deschner, J.5
Gassner, R.6
Butterfield, T.A.7
Agarwal, S.8
-
13
-
-
80755171253
-
SOX trio decrease in the articular cartilage with the advancement of osteoarthritis
-
Lee, J.S.; Im, G.I. SOX trio decrease in the articular cartilage with the advancement of osteoarthritis. Connect. Tissue Res. 2011, 52, 496-502.
-
(2011)
Connect. Tissue Res.
, vol.52
, pp. 496-502
-
-
Lee, J.S.1
Im, G.I.2
-
14
-
-
84872455053
-
Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression
-
Wang, Q.; Siminovitch, K.A.; Downey, G.P.; McCulloch, C.A. Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression. Biochem. J. 2013, 449, 771-782.
-
(2013)
Biochem. J.
, vol.449
, pp. 771-782
-
-
Wang, Q.1
Siminovitch, K.A.2
Downey, G.P.3
McCulloch, C.A.4
-
15
-
-
0036289135
-
Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3
-
Kanaki, T.; Bujo, H.; Mori, S.; Yanjuan, Z.; Takahashi, K.; Yokote, K.; Morisaki, N.; Saito, Y. Functional analysis of aortic endothelial cells expressing mutant PDGF receptors with respect to expression of matrix metalloproteinase-3. Biochem. Biophys. Res. Commun. 2002, 294, 231-237.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.294
, pp. 231-237
-
-
Kanaki, T.1
Bujo, H.2
Mori, S.3
Yanjuan, Z.4
Takahashi, K.5
Yokote, K.6
Morisaki, N.7
Saito, Y.8
-
16
-
-
78651275140
-
Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis
-
Yuan, F.L.; Chen, F.H.; Lu, W.G.; Li, X.; Li, J.P.; Li, C.W.; Xu, R.S.; Wu, F.R.; Hu, W.; Zhang, T.Y.; et al. Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis. Inflamm. Res. 2010, 59, 939-947.
-
(2010)
Inflamm. Res.
, vol.59
, pp. 939-947
-
-
Yuan, F.L.1
Chen, F.H.2
Lu, W.G.3
Li, X.4
Li, J.P.5
Li, C.W.6
Xu, R.S.7
Wu, F.R.8
Hu, W.9
Zhang, T.Y.10
-
17
-
-
84866444898
-
Intracellular calcium oscillations in articular chondrocytes induced by basic calcium phosphate crystals lead to cartilage degradation
-
Nguyen, C.; Lieberherr, M.; Bordat, C.; Velard, F.; Côme, D.; Lioté, F.; Ea, H.K. Intracellular calcium oscillations in articular chondrocytes induced by basic calcium phosphate crystals lead to cartilage degradation. Osteoarthr. Cartil. 2012, 20, 1399-1408.
-
(2012)
Osteoarthr. Cartil.
, vol.20
, pp. 1399-1408
-
-
Nguyen, C.1
Lieberherr, M.2
Bordat, C.3
Velard, F.4
Côme, D.5
Lioté, F.6
Ea, H.K.7
-
18
-
-
76349109033
-
Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway
-
Markova, B.; Albers, C.; Breitenbuecher, F.; Melo, J.V.; Brümmendorf, T.H.; Heidel, F.; Lipka, D.; Duyster, J.; Huber, C.; Fischer, T. Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway. Oncogene 2010, 29, 739-751.
-
(2010)
Oncogene
, vol.29
, pp. 739-751
-
-
Markova, B.1
Albers, C.2
Breitenbuecher, F.3
Melo, J.V.4
Brümmendorf, T.H.5
Heidel, F.6
Lipka, D.7
Duyster, J.8
Huber, C.9
Fischer, T.10
-
19
-
-
16844366670
-
ABL oncogenes and phosphoinositide 3-kinase: Mechanism of activation and downstream effectors
-
Kharas, M.G.; Fruman, D.A. ABL oncogenes and phosphoinositide 3-kinase: Mechanism of activation and downstream effectors. Cancer Res. 2005, 65, 2047-2053.
-
(2005)
Cancer Res.
, vol.65
, pp. 2047-2053
-
-
Kharas, M.G.1
Fruman, D.A.2
-
20
-
-
0036320205
-
Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
-
Edinger, A.L.; Thompson, C.B. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol. Biol. Cell. 2002, 13, 2276-2288.
-
(2002)
Mol. Biol. Cell.
, vol.13
, pp. 2276-2288
-
-
Edinger, A.L.1
Thompson, C.B.2
-
21
-
-
84890303026
-
Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D
-
doi:10.1186/1478-811X-11-3
-
Razmara, M.; Heldin, C.H.; Lennartsson, J. Platelet-derived growth factor-induced Akt phosphorylation requires mTOR/Rictor and phospholipase C-γ1, whereas S6 phosphorylation depends on mTOR/Raptor and phospholipase D. Cell. Commun. Signal. 2013, 11, doi:10.1186/1478-811X-11-3.
-
(2013)
Cell. Commun. Signal.
, vol.11
-
-
Razmara, M.1
Heldin, C.H.2
Lennartsson, J.3
-
22
-
-
33750068623
-
mTOR, translation initiation and cancer
-
Mamane, Y.; Petroulakis, E.; LeBacquer, O.; Sonenberg, N. mTOR, translation initiation and cancer. Oncogene 2006, 25, 6416-6422.
-
(2006)
Oncogene
, vol.25
, pp. 6416-6422
-
-
Mamane, Y.1
Petroulakis, E.2
LeBacquer, O.3
Sonenberg, N.4
-
23
-
-
84857014229
-
Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia
-
Zhang, T.; Lu, X.; Li, J.; Chidiac, P.; Sims, S.M.; Feng, Q. Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia. Basic Res. Cardiol. 2012, 107, 1435-1803.
-
(2012)
Basic Res. Cardiol.
, vol.107
, pp. 1435-1803
-
-
Zhang, T.1
Lu, X.2
Li, J.3
Chidiac, P.4
Sims, S.M.5
Feng, Q.6
-
24
-
-
0034704070
-
Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor. Potential for pharmacological intervention
-
Attur, M.G.; Dave, M.; Cipolletta, C.; Kang, P.; Goldring, M.B.; Patel, I.R.; Abramson, S.B.; Amin, A.R. Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor. Potential for pharmacological intervention. J. Biol. Chem. 2000, 275, 40307-40315.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40307-40315
-
-
Attur, M.G.1
Dave, M.2
Cipolletta, C.3
Kang, P.4
Goldring, M.B.5
Patel, I.R.6
Abramson, S.B.7
Amin, A.R.8
-
25
-
-
84860277806
-
Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Ca in chondrocytes
-
Chen, Q.; Zhang, B.; Yi, T.; Xia, C. Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Ca in chondrocytes. Folia Histochem. Cytobiol. 2012, 50, 137-143.
-
(2012)
Folia Histochem. Cytobiol.
, vol.50
, pp. 137-143
-
-
Chen, Q.1
Zhang, B.2
Yi, T.3
Xia, C.4
-
26
-
-
84855718266
-
17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway
-
Huang, J.G.; Xia, C.; Zheng, X.P.; Yi, T.T.; Wang, X.Y.; Song, G.; Zhang, B. 17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway. Cell. Mol. Biol. Lett. 2011, 16, 564-575.
-
(2011)
Cell. Mol. Biol. Lett.
, vol.16
, pp. 564-575
-
-
Huang, J.G.1
Xia, C.2
Zheng, X.P.3
Yi, T.T.4
Wang, X.Y.5
Song, G.6
Zhang, B.7
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