Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

PLoS Pathogens

Volumn 11, Issue 6, 2015, Pages

  van ‘t Wout, Emily F A ^a,b   van Schadewijk, Annemarie ^a   van Boxtel, Ria ^c   Dalton, Lucy E ^b   Clarke, Hanna J ^b   Tommassen, Jan ^c   Marciniak, Stefan J ^b   Hiemstra, Pieter S ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PROTEINASE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; INITIATION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PYOCYANINE; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; VIRULENCE FACTOR; X BOX BINDING PROTEIN 1; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R15A PROTEIN, HUMAN;

AIRWAY; ANIMAL CELL; ARTICLE; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOTOXICITY ASSAY; EMBRYO; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PSEUDOMONAS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; CELL CULTURE; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; PSEUDOMONAS AERUGINOSA; RESPIRATORY MUCOSA;

BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

BLOTTING, WESTERN; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HUMANS; PROTEIN PHOSPHATASE 1; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RESPIRATORY MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; VIRULENCE FACTORS;

EID: 84936775810     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004946     Document Type: Article

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