Cardiac-specific overexpression of metallothionein attenuates myocardial remodeling and contractile dysfunction in l-NAME-induced experimental hypertension: Role of autophagy regulation

Toxicology Letters

Volumn 237, Issue 2, 2015, Pages 121-132

  Yang, Lifang ^a,b   Gao, Jian Yuan ^a   Ma, Jipeng ^a   Xu, Xihui ^b   Wang, Qiurong ^b   Xiong, Lize ^a   Yang, Jian ^a,b   Ren, Jun ^a,b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF WYOMING COLLEGE OF HEALTH SCIENCES   (United States)

Author keywords

Autophagy; Hypertensive heart disease; L NAME; Metallothionein

Indexed keywords

CALCIUM; GLUTATHIONE; GLUTATHIONE DISULFIDE; MAMMALIAN TARGET OF RAPAMYCIN; METALLOTHIONEIN; N(G) NITROARGININE METHYL ESTER; PROTEIN P62; PROTEIN P70; SODIUM PHOSPHATE COTRANSPORTER 2B; RAPAMYCIN; REACTIVE OXYGEN METABOLITE;

ADULT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; DIASTOLIC BLOOD PRESSURE; EXPERIMENTAL HYPERTENSION; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE WALL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART RIGHT VENTRICLE ENDSYSTOLIC VOLUME; HEART VENTRICLE HYPERTROPHY; HISTOLOGY; MALE; MEAN ARTERIAL PRESSURE; MOUSE; MYOCARDIAL DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYSTOLIC BLOOD PRESSURE; ANIMAL; CHEMICALLY INDUCED; HEART CONTRACTION; HEART MUSCLE; HYPERTENSION; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; CALCIUM; HYPERTENSION; MALE; METALLOTHIONEIN; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; NG-NITROARGININE METHYL ESTER; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIROLIMUS;

EID: 84934913021     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.06.005     Document Type: Article

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