메뉴 건너뛰기




Volumn 49, Issue 2, 1999, Pages 297-305

Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes

Author keywords

Antioxidant defense system; Catalase; Glutathione peroxidase (GSH Px); Hepatocytes; Rat; Reactive oxygen species (ROS); Superoxide dismutase (SOD)

Indexed keywords

BUTHIONINE SULFOXIMINE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALEIC ACID DIETHYL ESTER; METALLOTHIONEIN; SUPEROXIDE DISMUTASE; ZINC;

EID: 0345280793     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/49.2.297     Document Type: Article
Times cited : (60)

References (48)
  • 2
    • 0027081945 scopus 로고
    • Examination of potential mechanism(s) of metallothionein induction by diethyl maleate
    • Bauman, J. W., Liu, Y. P., Andrews, G. K., and Klaassen, C. D. (1992). Examination of potential mechanism(s) of metallothionein induction by diethyl maleate. Toxicol. Appl. Pharmacol. 117, 226-232.
    • (1992) Toxicol. Appl. Pharmacol. , vol.117 , pp. 226-232
    • Bauman, J.W.1    Liu, Y.P.2    Andrews, G.K.3    Klaassen, C.D.4
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. (1976). A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 4
    • 0018567627 scopus 로고
    • Protection of carbon tetrachloride (CCL4)-induced hepatotoxicity by zinc: Role of metallothionein
    • Cagen, S. Z., and Klaassen, C, D. (1979). Protection of carbon tetrachloride (CCL4)-induced hepatotoxicity by zinc: Role of metallothionein. Toxicol. Appl. Pharmacol 51, 107-116.
    • (1979) Toxicol. Appl. Pharmacol , vol.51 , pp. 107-116
    • Cagen, S.Z.1    Klaassen, C.D.2
  • 5
    • 0029048855 scopus 로고
    • The oxidative stress response
    • Camhi, S. L., Lee, P., and Choi, A. M. K. (1995), The oxidative stress response. New Horiz. 3, 170-182.
    • (1995) New Horiz. , vol.3 , pp. 170-182
    • Camhi, S.L.1    Lee, P.2    Choi, A.M.K.3
  • 6
    • 0026538918 scopus 로고
    • Protective roles of metallothionein and glutathione in hepatotoxicity of cadmium
    • Chan, H. M., and Cherian, M. G. (1992). Protective roles of metallothionein and glutathione in hepatotoxicity of cadmium. Toxicology 72, 281-290.
    • (1992) Toxicology , vol.72 , pp. 281-290
    • Chan, H.M.1    Cherian, M.G.2
  • 7
    • 0027513696 scopus 로고
    • Metallothionein protects DNA from oxidative damage
    • Chubatsu, L. S., and Meneghini, R. (1993). Metallothionein protects DNA from oxidative damage. Biochem. J. 291, 193-198.
    • (1993) Biochem. J. , vol.291 , pp. 193-198
    • Chubatsu, L.S.1    Meneghini, R.2
  • 8
    • 0027771175 scopus 로고
    • Identification of oxygen responsive element in the 5′-flanking region of the human glutathione peroxidase gene
    • Cowan, D. B., Weisel R. D., and Wiliams, W. G. (1993). Identification of oxygen responsive element in the 5′-flanking region of the human glutathione peroxidase gene. J. Biol. Chem. 268, 26904-26910.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26904-26910
    • Cowan, D.B.1    Weisel, R.D.2    Wiliams, W.G.3
  • 9
    • 0023655369 scopus 로고
    • Protein damage and degradation by oxygen radicals: I. General aspects
    • Davies, K. J. A. (1987). Protein damage and degradation by oxygen radicals: I. General aspects. J. Biol. Chem. 262, 9895-9901.
    • (1987) J. Biol. Chem. , vol.262 , pp. 9895-9901
    • Davies, K.J.A.1
  • 10
    • 0020455632 scopus 로고
    • Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues
    • Eaton, D. L., and Toal, B. F. (1982). Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues. Toxicol. Appl. Pharmacol. 66, 134-142.
    • (1982) Toxicol. Appl. Pharmacol. , vol.66 , pp. 134-142
    • Eaton, D.L.1    Toal, B.F.2
  • 11
    • 0032053707 scopus 로고    scopus 로고
    • Oxygen radicals and signaling
    • Finkel, T. (1998). Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10, 248-253.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 248-253
    • Finkel, T.1
  • 12
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling, K. K., Minieri C. A., Ollerenshaw, J. D., and Alexander, R. W. (1994). Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 74, 1141-1148.
    • (1994) Circ. Res. , vol.74 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 13
    • 0018666729 scopus 로고
    • Potential specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith, O. W., and Meister, A. (1979). Potential specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J. Biol. Chem. 254, 7758-7760.
    • (1979) J. Biol. Chem. , vol.254 , pp. 7758-7760
    • Griffith, O.W.1    Meister, A.2
  • 14
    • 0002508819 scopus 로고
    • Protection against oxidants in biological systems: The Superoxide theory of oxygen toxicity
    • B. Halliwell, J. M. C. Gutterige, Eds., Clarendon Press, Oxford
    • Halliwell, B., and Gutterige, J. M. C. (1989). Protection against oxidants in biological systems: The Superoxide theory of oxygen toxicity. In Free Radicals in Biology and Medicine (B. Halliwell, J. M. C. Gutterige, Eds.), pp. 86-187. Clarendon Press, Oxford.
    • (1989) Free Radicals in Biology and Medicine , pp. 86-187
    • Halliwell, B.1    Gutterige, J.M.C.2
  • 15
    • 0022555879 scopus 로고
    • Metallothionein
    • Hamer, D. H. (1986). Metallothionein. Anna. Rev. Biochem. 55, 913-951.
    • (1986) Anna. Rev. Biochem. , vol.55 , pp. 913-951
    • Hamer, D.H.1
  • 16
    • 0017064979 scopus 로고
    • A fluorimetric method for determination of oxidized and reduced glutathione in tissues
    • Hissin, P. J., and Hilf, R. (1976). A fluorimetric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74, 214-226.
    • (1976) Anal. Biochem. , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 17
    • 0026131493 scopus 로고
    • Molecular structure of a functional rat gene for manganese-containing Superoxide dismutase
    • Ho, Y. S., Howard, A. J., and Crapo, J. D. (1991). Molecular structure of a functional rat gene for manganese-containing Superoxide dismutase. Am. J. Resp. Cell Mol. Biol. 4, 278-286.
    • (1991) Am. J. Resp. Cell Mol. Biol. , vol.4 , pp. 278-286
    • Ho, Y.S.1    Howard, A.J.2    Crapo, J.D.3
  • 18
    • 0030884938 scopus 로고    scopus 로고
    • Differential regulation of γ-glutamylcysteine synthetase heavy and light subunit gene expression
    • Huang, Z., and Lu, S. C. (1997). Differential regulation of γ-glutamylcysteine synthetase heavy and light subunit gene expression. Biochem. J. 326, 167-172.
    • (1997) Biochem. J. , vol.326 , pp. 167-172
    • Huang, Z.1    Lu, S.C.2
  • 20
    • 0002811075 scopus 로고
    • Biochemical methods of studying hepatotoxicity
    • R. G. Meek, S. D. Harrison, and R. J. Bull, Eds., CRC Press, Boston
    • Kodavanti, P. R. S., and Mehendale, H. M., (1991). Biochemical methods of studying hepatotoxicity. In Hepatotoxicology (R. G. Meek, S. D. Harrison, and R. J. Bull, Eds.), pp. 241-325. CRC Press, Boston.
    • (1991) Hepatotoxicology , pp. 241-325
    • Kodavanti, P.R.S.1    Mehendale, H.M.2
  • 21
    • 0017067418 scopus 로고
    • Glutathione peroxidase activity in selenium-deficient rat liver
    • Lawrence, R. A., and Burk, R. F. (1976). Glutathione peroxidase activity in selenium-deficient rat liver. Biochem. Biophys. Res. Commun. 71, 952-958.
    • (1976) Biochem. Biophys. Res. Commun. , vol.71 , pp. 952-958
    • Lawrence, R.A.1    Burk, R.F.2
  • 22
    • 0026022671 scopus 로고
    • The protective effect of metallothionein on the toxicity of various metals in rat primary hepatocytes culture
    • Liu, J., Kershaw, W. C., and Klaassen, C. D. (1991). The protective effect of metallothionein on the toxicity of various metals in rat primary hepatocytes culture. Toxicol. Appl. Pharmacol. 107, 27-34.
    • (1991) Toxicol. Appl. Pharmacol. , vol.107 , pp. 27-34
    • Liu, J.1    Kershaw, W.C.2    Klaassen, C.D.3
  • 23
    • 0029020218 scopus 로고
    • Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes
    • Lo, Y. Y. C., and Cruz, T. F. (1995). Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J. Biol. Chem. 270, 11727-11730.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11727-11730
    • Lo, Y.Y.C.1    Cruz, T.F.2
  • 24
    • 0002191974 scopus 로고
    • Catalase
    • L. Bergmeyer, Ed., Academic Press, New York
    • Lück, H. (1971). Catalase. In Methods of Enzymatic Analysis (L. Bergmeyer, Ed.), pp. 885-889. Academic Press, New York.
    • (1971) Methods of Enzymatic Analysis , pp. 885-889
    • Lück, H.1
  • 25
    • 0027987261 scopus 로고
    • Improved postischemic ventricular function recovery by amphetamine is linked with its ability to induce heat shock
    • Maulik, N., Wei, Z., Liu, X., Engelman, R. M., Rousou, J. A., and Das, D. K. (1994). Improved postischemic ventricular function recovery by amphetamine is linked with its ability to induce heat shock. Mol. Cell. Biochem. 137, 17-24.
    • (1994) Mol. Cell. Biochem. , vol.137 , pp. 17-24
    • Maulik, N.1    Wei, Z.2    Liu, X.3    Engelman, R.M.4    Rousou, J.A.5    Das, D.K.6
  • 26
    • 0024425516 scopus 로고
    • Human fibroblasts release reactive oxygen species in response to interleukine-1 or tumor necrosis factor-α
    • Meier, B., Radeke, H. H., Selle, S., Younes, M., Sies, H., Resch, K., and Habermehi, G. G. (1989). Human fibroblasts release reactive oxygen species in response to interleukine-1 or tumor necrosis factor-α. Biochem. J. 263, 539-545.
    • (1989) Biochem. J. , vol.263 , pp. 539-545
    • Meier, B.1    Radeke, H.H.2    Selle, S.3    Younes, M.4    Sies, H.5    Resch, K.6    Habermehi, G.G.7
  • 27
    • 0028273316 scopus 로고
    • Glutathione, ascorbate, and cellular protection
    • Meister, A. (1994). Glutathione, ascorbate, and cellular protection. Cancer Res. 54, 1969-1975.
    • (1994) Cancer Res. , vol.54 , pp. 1969-1975
    • Meister, A.1
  • 28
    • 0024266401 scopus 로고
    • V79 Chinese-hamster cells rendered resistant to high cadmium concentration also become resistant to oxidative stress
    • Mello-Filho, A. C., Chubatsu, L. S., and Meneghini, R. (1988). V79 Chinese-hamster cells rendered resistant to high cadmium concentration also become resistant to oxidative stress. Biochem. J. 256, 475-479.
    • (1988) Biochem. J. , vol.256 , pp. 475-479
    • Mello-Filho, A.C.1    Chubatsu, L.S.2    Meneghini, R.3
  • 29
    • 0020478933 scopus 로고
    • Status of the mitochondrial pool of glutathione in the isolated hepatocyte
    • Meredith, M. J., and Reed, D. J. (1982). Status of the mitochondrial pool of glutathione in the isolated hepatocyte. J. Biol. Chem. 257, 3747-3753.
    • (1982) J. Biol. Chem. , vol.257 , pp. 3747-3753
    • Meredith, M.J.1    Reed, D.J.2
  • 30
    • 0015523099 scopus 로고
    • The role of Superoxide anion in autoxidation of epinephrine and a simple assay for Superoxide dismutase
    • Misra, H. P., and Fridovich, I. (1971). The role of Superoxide anion in autoxidation of epinephrine and a simple assay for Superoxide dismutase. J. Biol. Chem. 247, 3170-3175.
    • (1971) J. Biol. Chem. , vol.247 , pp. 3170-3175
    • Misra, H.P.1    Fridovich, I.2
  • 31
    • 0030632095 scopus 로고    scopus 로고
    • Antioxidant activity of metallothionein compared with reduced glutathione
    • Miura, T. Muraoka, S., and Ogiso, T. (1997). Antioxidant activity of metallothionein compared with reduced glutathione. Life Sci. 60, PL301-309.
    • (1997) Life Sci. , vol.60
    • Miura, T.1    Muraoka, S.2    Ogiso, T.3
  • 32
    • 0028960086 scopus 로고
    • Induction of metallothionein gene expression by epidermal growth factor and its inhibition by transforming growth factor-β and dexamethasone in rat hepatocytes
    • Moffatt, P., Plaa, G. L., and Denizeau, F. (1995). Induction of metallothionein gene expression by epidermal growth factor and its inhibition by transforming growth factor-β and dexamethasone in rat hepatocytes. Hepatology 21, 1038-1044.
    • (1995) Hepatology , vol.21 , pp. 1038-1044
    • Moffatt, P.1    Plaa, G.L.2    Denizeau, F.3
  • 33
    • 0030069147 scopus 로고    scopus 로고
    • Rat hepatocytes with elevated metallothionein expression are resistant to N-Methyl-N′-nitro-N-nitrosoguanidine cytotoxicity
    • Moffatt, P., Plaa, G. L., and Denizeau, F. (1996). Rat hepatocytes with elevated metallothionein expression are resistant to N-Methyl-N′-nitro-N-nitrosoguanidine cytotoxicity. Toxicol. Appl. Pharmacol. 136, 200-207.
    • (1996) Toxicol. Appl. Pharmacol. , vol.136 , pp. 200-207
    • Moffatt, P.1    Plaa, G.L.2    Denizeau, F.3
  • 35
    • 0023178325 scopus 로고
    • Importance of the glutathione cycle in drug metabolism
    • Moldeus, P., and Quanguan, J. (1987). Importance of the glutathione cycle in drug metabolism. Pharmacol. Ther. 33, 37-40.
    • (1987) Pharmacol. Ther. , vol.33 , pp. 37-40
    • Moldeus, P.1    Quanguan, J.2
  • 36
    • 0023906695 scopus 로고
    • Effect of glutathione depletion and induction of metallothioneins on the cytotoxicity of an organic hydroperoxide in cultured mammalian cells
    • Ochi, T. (1988). Effect of glutathione depletion and induction of metallothioneins on the cytotoxicity of an organic hydroperoxide in cultured mammalian cells. Toxicology 50, 257-268.
    • (1988) Toxicology , vol.50 , pp. 257-268
    • Ochi, T.1
  • 38
    • 0027265192 scopus 로고
    • Flow cytometric analysis of the effects of tri-n-butylin chloride on cytosolic free calcium and thiol levels in isolated rainbow trout hepatocytes
    • Reader, S., Marion, M., and Denizeau, F. (1993). Flow cytometric analysis of the effects of tri-n-butylin chloride on cytosolic free calcium and thiol levels in isolated rainbow trout hepatocytes. Toxicology 80, 117-129.
    • (1993) Toxicology , vol.80 , pp. 117-129
    • Reader, S.1    Marion, M.2    Denizeau, F.3
  • 39
    • 0025317268 scopus 로고
    • Glutathione: Toxicological implications
    • Reed, D. J. (1990). Glutathione: Toxicological implications. Annu. Rev. Pharmacol. Toxicol. 30, 603-631.
    • (1990) Annu. Rev. Pharmacol. Toxicol. , vol.30 , pp. 603-631
    • Reed, D.J.1
  • 40
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen, PO. (1976). Preparation of isolated rat liver cells. Methods Cell Biol. 13, 29-83.
    • (1976) Methods Cell Biol. , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 42
    • 0027161361 scopus 로고
    • Effects of zinc on rat hepatoma HTC cells and primary cultured rat hepatocytes
    • Steinebach, O. M., and Wolterbeek, HT. (1993). Effects of zinc on rat hepatoma HTC cells and primary cultured rat hepatocytes. Toxicol. Appl. Pharmacol. 118, 245-254.
    • (1993) Toxicol. Appl. Pharmacol. , vol.118 , pp. 245-254
    • Steinebach, O.M.1    Wolterbeek, H.T.2
  • 43
    • 0028200902 scopus 로고
    • Effects of copper on rat hepatoma HTC cells and primary cultured rat hepatocytes
    • Steinebach, O. M., and Wolterbeek, H. T. (1994). Effects of copper on rat hepatoma HTC cells and primary cultured rat hepatocytes. J. Inorg. Biochem. 53, 27-48.
    • (1994) J. Inorg. Biochem. , vol.53 , pp. 27-48
    • Steinebach, O.M.1    Wolterbeek, H.T.2
  • 44
    • 25944475952 scopus 로고
    • Inhibition of cell membrane lipid peroxidation by cadmium and zinc metallothionein
    • Thomas, J. P., Bachowski, G. L., and Girotti A. W. (1986). Inhibition of cell membrane lipid peroxidation by cadmium and zinc metallothionein. Biochim. Biophys. Acta 827, 381-392.
    • (1986) Biochim. Biophys. Acta , vol.827 , pp. 381-392
    • Thomas, J.P.1    Bachowski, G.L.2    Girotti, A.W.3
  • 45
    • 0344141302 scopus 로고
    • Possible role for metallothionein in protection against radiation-induced oxidative stress: Kinetics and mechanism of its reaction with Superoxide and hydroxyl radicals
    • Thornalley, P. J., and Vasäk, M. (1985). Possible role for metallothionein in protection against radiation-induced oxidative stress: Kinetics and mechanism of its reaction with Superoxide and hydroxyl radicals. Biochim. Biophys. Acta 884, 448-461.
    • (1985) Biochim. Biophys. Acta , vol.884 , pp. 448-461
    • Thornalley, P.J.1    Vasäk, M.2
  • 46
    • 0002913598 scopus 로고
    • The physiological functions of glutathione
    • J. Miquel, A. T. Quintanilha, and H. Weber, Eds. CRC Press, Boca Raton
    • Vina, J. R., Spez, G. T., and Vina, J. (1989). The physiological functions of glutathione. In Handbook of Free Radicals and Antioxidants in Biomedicine (J. Miquel, A. T. Quintanilha, and H. Weber, Eds.), vol. II, pp. 121-132. CRC Press, Boca Raton.
    • (1989) Handbook of Free Radicals and Antioxidants in Biomedicine , vol.2 , pp. 121-132
    • Vina, J.R.1    Spez, G.T.2    Vina, J.3
  • 47
    • 0002289094 scopus 로고    scopus 로고
    • Mediation of signal transduction by oxidant
    • E. Cadenas And S. M. Wolin, Eds., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Wolin, S. M. and Mohazzab K. M. (1997). Mediation of signal transduction by oxidant. In Oxidative Stress and the Molecular Biology of Antioxidant Defenses. (E. Cadenas And S. M. Wolin, Eds.), pp 21-47. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1997) Oxidative Stress and the Molecular Biology of Antioxidant Defenses , pp. 21-47
    • Wolin, S.M.1    Mohazzab, K.M.2
  • 48
    • 0019378687 scopus 로고
    • Relationship between liver and kidney levels of glutathione and metallothionein in rats
    • Wong, K. L., and Klaassen, C. D. (1981). Relationship between liver and kidney levels of glutathione and metallothionein in rats. Toxicology 19, 39-47.
    • (1981) Toxicology , vol.19 , pp. 39-47
    • Wong, K.L.1    Klaassen, C.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.