Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 2, 2015, Pages 310-318

  Shen, Cheng ^a   Wang, Cong ^a   Fan, Fan ^a   Yang, Zhiyin ^b   Cao, Quan ^a   Liu, Xiangwei ^a   Sun, Xiaolei ^a   Zhao, Xiaona ^a   Wang, Peng ^a   Ma, Xin ^a   Zhu, Hong ^a   Dong, Zhen ^a   Zou, Yunzeng ^a   Hu, Kai ^a   Sun, Aijun ^a   Ge, Junbo ^a  

^a FUDAN UNIVERSITY   (China)

^b JINING MEDICAL UNIVERSITY   (China)

Author keywords

ALDH2; Autophagy; Beclin 1; Heart failure; Pressure overload

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; BECLIN 1; ADENYLATE KINASE; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 2, MOUSE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ADULT; ALDEHYDE DEHYDROGENASE ISOENZYME 2 DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME DEFICIENCY; ENZYME PHOSPHORYLATION; HEART FAILURE; HEART FUNCTION; HEART INJURY; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART VENTRICLE OVERLOAD; IMMUNOPRECIPITATION; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SARCOMERE; TRANSTHORACIC ECHOCARDIOGRAPHY; ULTRASTRUCTURE; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CARDIOMEGALY; DEFICIENCY; ENZYMOLOGY; HEART; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PRESSURE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

MUS;

ADENYLATE KINASE; ALDEHYDE DEHYDROGENASE; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; CARDIOMEGALY; HEART; MALE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MYOCARDIUM; PHOSPHORYLATION; PRESSURE; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84919787413     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.07.014     Document Type: Article

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