Mechanical stress triggers cardiomyocyte autophagy through angiotensin II type 1 receptor-mediated p38MAP kinase independently of angiotensin II

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Lin, Li ^a   Tang, Chuyi ^a   Xu, Jianfeng ^b   Ye, Yong ^b   Weng, Liqing ^b   Wei, Wei ^a   Ge, Junbo ^b   Liu, Xuebo ^a   Zou, Yunzeng ^b  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEIN LC3B II; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CARDIOMYOCYTE HYPERTROPHY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MALE; MECHANICAL STRESS; MOUSE; NEWBORN; NONHUMAN; PROTEIN FUNCTION; RAT; SURGICAL TECHNIQUE; TRANSVERSE AORTA CONSTRICTION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANGIOTENSIN II; ANIMALS; AUTOPHAGY; BIOMECHANICAL PHENOMENA; CARDIOMEGALY; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; STRESS, PHYSIOLOGICAL;

EID: 84896134264     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089629     Document Type: Article

References (30)

1. Zanchetti A (2010) HYPERTENSION Cardiac hypertrophy as a target of antihypertensive therapy. Nature Reviews Cardiology 7: 66-67.
2. Francisco Nistal J, Garcia R, Villar AV, Llano M, Cobo M, et al. (2011) Plasma Levels of MicroRNA-133a Predict Complete Regression of Left Ventricular Hypertrophy After Valve Replacement in Patients With Aortic Stenosis. Circulation 124.
3. Hanatani S, Izumiya Y, Araki S, Rokutanda T, Walsh K, et al. (2011) Fast/Glycolytic Skeletal Muscle Growth Attenuates Cardiac Dysfunction and Remodeling After Experimental Myocardial Infarction. Circulation 124.
4. Shah AM, Mann DL (2011) Heart Failure 1 In search of new therapeutic targets and strategies for heart failure: recent advances in basic science. Lancet 378: 704-712.
5. Diwan A, Wansapura J, Syed FM, Matkovich SJ, Lorenz JN, et al. (2008) Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation. Circulation 117: 396-404.
6. Vigliano CA, Meckert PMC, Diez M, Favaloro LE, Cortes C, et al. (2011) Cardiomyocyte Hypertrophy, Oncosis, and Autophagic Vacuolization Predict Mortality in Idiopathic Dilated Cardiomyopathy With Advanced Heart Failure. Journal of the American College of Cardiology 57: 1523-1531.
7. Hein S, Arnon E, Kostin S, Schonburg M, Elsasser A, et al. (2003) Progression from compensated hypertrophy to failure in the pressure-overloaded human heart - Structural deterioration and compensatory mechanisms. Circulation 107: 984-991. (Pubitemid 36258721)
8. Wang ZV, Rothermel BA, Hill JA (2010) Autophagy in Hypertensive Heart Disease. Journal of Biological Chemistry 285: 8509-8514.
9. Rothermel BA, Hill JA (2008) Autophagy in Load-Induced Heart Disease. Circulation Research 103: 1363-1369.
10. Nakai A, Yamaguchi O, Takeda T, Higuchi Y, Hikoso S, et al. (2007) The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nature Medicine 13: 619-624. (Pubitemid 46828485)
11. Gottlieb RA, Mentzer RM Jr (2010) Autophagy During Cardiac Stress: Joys and Frustrations of Autophagy. Annual Review of Physiology. 45-59.
12. Porrello ER, D'Amore A, Curl CL, Allen AM, Harrap SB, et al. (2009) Angiotensin II Type 2 Receptor Antagonizes Angiotensin II Type 1 Receptor-Mediated Cardiomyocyte Autophagy. Hypertension 53: 1032-1040.
13. Sbroggio M, Carnevale D, Bertero A, Cifelli G, De Blasio E, et al. (2011) IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload. Cardiovascular Research 91: 456-464.
14. Zou YZ, Lin L, Ye Y, Wei JM, Zhou N, et al. (2012) Qiliqiangxin Inhibits the Development of Cardiac Hypertrophy, Remodeling, and Dysfunction During 4 Weeks of Pressure Overload in Mice. Journal of Cardiovascular Pharmacology 59: 268-280.
15. Zou YZ, Akazawa H, Qin YJ, Sano M, Takano H, et al. (2004) Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nature Cell Biology 6: 499-506. (Pubitemid 38786592)
16. Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, et al. (2007) p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature 446: 444-448. (Pubitemid 46474597)
17. Bueno OF, Molkentin JD (2002) Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death. Circulation Research 91: 776-781. (Pubitemid 35285074)
18. Sadoshima J, Izumo S (1993) MOLECULAR CHARACTERIZATION OF ANGIOTENSIN-II-INDUCED HYPERTROPHY OF CARDIAC MYOCYTES AND HYPERPLASIA OF CARDIAC FIBROBLASTS - CRITICAL ROLE OF THE AT(1) RECEPTOR SUBTYPE. Circulation Research 73: 413-423. (Pubitemid 23238726)
19. Lin L, Gong H, Ge J, Jiang G, Zhou N, et al. (2011) High density lipoprotein downregulates angiotensin II type 1 receptor and inhibits angiotensin II-induced cardiac hypertrophy. Biochemical and Biophysical Research Communications 404: 28-33.
20. Zhou N, Li L, Wu J, Gong H, Niu Y, et al. (2010) Mechanical stress-evoked but angiotensin II-independent activation of angiotensin II type 1 receptor induces cardiac hypertrophy through calcineurin pathway. Biochemical and Biophysical Research Communications 397: 263-269.
21. Pfaffl MW (2001) A new mathematical model for relative quantification in realtime RT-PCR. Nucleic Acids Research 29.
22. Ni H-M, Bockus A, Boggess N, Jaeschke H, Ding W-X (2012) Activation of autophagy protects against acetaminophen-induced hepatotoxicity. Hepatology 55: 222-231.
23. Rubinsztein DC, Marino G, Kroemer G (2011) Autophagy and Aging. Cell 146: 682-695.
24. Zhu H, Tannous P, Johnstone JL, Kong Y, Shelton JM, et al. (2007) Cardiac autophagy is a maladaptive response to hemodynamic stress. Journal of Clinical Investigation 117: 1782-1793. (Pubitemid 47036312)
25. Mehta PK, Griendling KK (2007) Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. American Journal of Physiology-Cell Physiology 292: C82-C97. (Pubitemid 46127306)
26. Reudelhuber TL, Bernstein KE, Delafontaine P (2007) Is angiotensin II a direct mediator of left ventricular hypertrophy? Time for another look. Hypertension 49: 1196-1201. (Pubitemid 46809352)
27. Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, et al. (2011) Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A. Journal of Molecular and Cellular Cardiology 51: 988-996.
28. Kang S, Chemaly ER, Hajjar RJ, Lebeche D (2011) Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways. Journal of Biological Chemistry 286: 18465-18473.
29. Finckenberg P, Eriksson O, Baumann M, Merasto S, Lalowski MM, et al. (2012) Caloric Restriction Ameliorates Angiotensin II-Induced Mitochondrial Remodeling and Cardiac Hypertrophy. Hypertension 59: 76-U209.
30. De Meyer GRY, De Keulenaer GW, Martinet W (2010) Role of autophagy in heart failure associated with aging. Heart Failure Reviews 15: 423-430.