Dimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy

Autophagy

Volumn 10, Issue 5, 2014, Pages 930-932

  Mariño, Guillermo ^a,b,c   Pietrocola, Federico ^a,b,c   Kong, Yongli ^d   Eisenberg, Tobias ^e   Hill, Joseph A ^d   Madeo, Frank ^e   Kroemer, Guido ^a,b,c,f  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITY OF GRAZ   (Austria)

^f HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

Acetyl coenzyme A; Dilated cardiopathy; Macroautophagy

Indexed keywords

ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE CITRATE LYASE; BECLIN 1; DIMETHYL ALPHA KETOGLUTARATE; GLUTARIC ACID DERIVATIVE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; UNCLASSIFIED DRUG; 2 OXOGLUTARIC ACID; DIMETHYL ALPHA-KETOGLUTARATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; AUTOPHAGY; AUTOPHAGY INHIBITION; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CYTOSOL; HEART AFTERLOAD; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART VENTRICLE OVERLOAD; HEMODYNAMIC STRESS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MOUSE; NONHUMAN; STARVATION; THORACIC AORTA; THORACIC AORTIC CONSTRICTION; WILD TYPE; ADAPTATION; ANIMAL; BLOOD PRESSURE; CARDIOMYOPATHY, DILATED; CELL CULTURE; DOWN REGULATION; DRUG EFFECTS; HYPERTROPHY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; AUTOPHAGY; BLOOD PRESSURE; CARDIOMYOPATHY, DILATED; CELLS, CULTURED; DOWN-REGULATION; HUMANS; HYPERTROPHY; KETOGLUTARIC ACIDS; MICE; MYOCYTES, CARDIAC;

EID: 84899738247     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.28235     Document Type: Article

References (0)