Heavy metal scavenger metallothionein attenuates ER stress-induced myocardial contractile anomalies: Role of autophagy

Toxicology Letters

Volumn 225, Issue 3, 2014, Pages 333-341

  Yang, Lifang ^a,b   Hu, Nan ^b   Jiang, Shasha ^b,c   Zou, Yunzeng ^c   Yang, Jian ^d   Xiong, Lize ^a   Ren, Jun ^b  

^a Department of Anesthesiology ^*  (China)

^b UNIVERSITY OF WYOMING   (United States)

^c FUDAN UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Cardiac function; ER stress; Metallothionein; Tunicamycin

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; CALCIUM ION; LC3B PROTEIN; METALLOTHIONEIN; PROTEIN; PROTEIN P62; TUNICAMYCIN; ULK1 PROTEIN; UNCLASSIFIED DRUG; 3-METHYLADENINE; ADENINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENDOPLASMIC RETICULUM STRESS; GENE OVEREXPRESSION; HEART CONTRACTION; HEART FUNCTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; IN VITRO STUDY; MALE; MOUSE; MYOCARDIAL DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; CYTOLOGY; HEART; HEART MUSCLE; METABOLISM; PHYSIOLOGY;

ACETYLCYSTEINE; ADENINE; ANIMALS; AUTOPHAGY; ECHOCARDIOGRAPHY; ENDOPLASMIC RETICULUM STRESS; HEART; MALE; METALLOTHIONEIN; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; TUNICAMYCIN;

EID: 84893471114     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.12.024     Document Type: Article

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