-
1
-
-
0015236835
-
Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids
-
Moelling K, Bolognesi DP, Bauer H et al (1971) Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. Nat New Biol 234:240-243
-
(1971)
Nat New Biol
, vol.234
, pp. 240-243
-
-
Moelling, K.1
Bolognesi, D.P.2
Bauer, H.3
-
2
-
-
0023673620
-
Identifi cation and characterization of HIVspecifi c RNase H by monoclonal antibody
-
Hansen J, Schulze T, Mellert W et al (1988) Identifi cation and characterization of HIVspecifi c RNase H by monoclonal antibody. EMBO J 7:239-243
-
(1988)
EMBO J
, vol.7
, pp. 239-243
-
-
Hansen, J.1
Schulze, T.2
Mellert, W.3
-
3
-
-
0014964695
-
RNAdependent DNA polymerase in virions of Rous sarcoma virus
-
Temin HM, Mizutani S (1970) RNAdependent DNA polymerase in virions of Rous sarcoma virus. Nature 226:1211-1213
-
(1970)
Nature
, vol.226
, pp. 1211-1213
-
-
Temin, H.M.1
Mizutani, S.2
-
4
-
-
0025085589
-
Interaction of HIV-1 RNase H with polypurine tract containing RNA-DNA hybrids
-
Wöhrl B, Moelling K (1990) Interaction of HIV-1 RNase H with polypurine tract containing RNA-DNA hybrids. Biochem 29: 10141-10147
-
(1990)
Biochem
, vol.29
, pp. 10141-10147
-
-
Wöhrl, B.1
Moelling, K.2
-
5
-
-
59649101866
-
Retroviral integrase superfamily: The structural perspective
-
Nowotny M (2009) Retroviral integrase superfamily: the structural perspective. EMBO Rep 10:144-151
-
(2009)
EMBO Rep
, vol.10
, pp. 144-151
-
-
Nowotny, M.1
-
6
-
-
0016340337
-
Reverse transcriptase and RNase H: Present in a murine virus and in both subunits of an avian virus
-
Moelling K (1974) Reverse transcriptase and RNase H: present in a murine virus and in both subunits of an avian virus. Cold Spring Harb Symp Quant Biol 39:969-973
-
(1974)
Cold Spring Harb Symp Quant Biol
, vol.39
, pp. 969-973
-
-
Moelling, K.1
-
7
-
-
0015421991
-
Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin
-
Keller W, Crouch R (1972) Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin. Proc Natl Acad Sci USA 69:3360-3364
-
(1972)
Proc Natl Acad Sci USA
, vol.69
, pp. 3360-3364
-
-
Keller, W.1
Crouch, R.2
-
8
-
-
0034917751
-
Phylogenetic analysis of ribonuclease H domains suggests a late, chimeric origin of LTR retrotransposable elements and retroviruses
-
Malik HS, Eickbush TH (2001) Phylogenetic analysis of ribonuclease H domains suggests a late, chimeric origin of LTR retrotransposable elements and retroviruses. Genome Res 11: 1187-1197
-
(2001)
Genome Res
, vol.11
, pp. 1187-1197
-
-
Malik, H.S.1
Eickbush, T.H.2
-
9
-
-
0025861490
-
Mutations of a conserved residue within HIV-1 ribonuclease H affects its exo-and endonuclease activities
-
Wöhrl B, Volkmann S, Moelling K (1991) Mutations of a conserved residue within HIV-1 ribonuclease H affects its exo-and endonuclease activities. J Mol Biol 220:801-818
-
(1991)
J Mol Biol
, vol.220
, pp. 801-818
-
-
Wöhrl, B.1
Volkmann, S.2
Moelling, K.3
-
10
-
-
0027410067
-
Enzymatic analysis of two HIV-1 reverse transcriptase mutants with mutations in carboxyl-terminal amino acid residues conserved among retroviral ribonucleases H
-
Volkmann S, Wöhrl BM, Tisdale M et al (1993) Enzymatic analysis of two HIV-1 reverse transcriptase mutants with mutations in carboxyl-terminal amino acid residues conserved among retroviral ribonucleases H. J Biol Chem 268:2674-2683
-
(1993)
J Biol Chem
, vol.268
, pp. 2674-2683
-
-
Volkmann, S.1
Wöhrl, B.M.2
Tisdale, M.3
-
11
-
-
0028969877
-
Inhibition of HIV-1 reverse transcription by triple-helix forming oligonucleotides with viral RNA
-
Volkmann S, Jendis J, Frauendorf A et al (1995) Inhibition of HIV-1 reverse transcription by triple-helix forming oligonucleotides with viral RNA. Nucl Acids Res 23:1204-1212
-
(1995)
Nucl Acids Res
, vol.23
, pp. 1204-1212
-
-
Volkmann, S.1
Jendis, J.2
Frauendorf, A.3
-
12
-
-
0035868713
-
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA
-
Sarafi anos SG, Das K, Tantillo C et al (2001) Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA. EMBO J 20:1449-1461
-
(2001)
EMBO J
, vol.20
, pp. 1449-1461
-
-
Sarafianos, S.G.1
Das, K.2
Tantillo, C.3
-
13
-
-
0016130809
-
Characterization of Reverse Transcriptase and RNase H from Friend murine leukemia virus
-
Moelling K (1974) Characterization of Reverse Transcriptase and RNase H from Friend murine leukemia virus. Virology 62:46-59
-
(1974)
Virology
, vol.62
, pp. 46-59
-
-
Moelling, K.1
-
14
-
-
0019949367
-
Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate
-
Summers J, Mason WS (1982) Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate. Cell 29:403-415
-
(1982)
Cell
, vol.29
, pp. 403-415
-
-
Summers, J.1
Mason, W.S.2
-
15
-
-
0020788833
-
Involvement of reverse transcription in the replication of caulifl ower mosaic virus: A detailed model and test of some aspects
-
Pfeiffer P, Hohn T (1983) Involvement of reverse transcription in the replication of caulifl ower mosaic virus: a detailed model and test of some aspects. Cell 33:781-789
-
(1983)
Cell
, vol.33
, pp. 781-789
-
-
Pfeiffer, P.1
Hohn, T.2
-
16
-
-
0020631413
-
Characterization of a foamy virus isolated from Cercopithecus aethiops lymphoblastoid cells
-
Neumann-Haefelin D, Rethwilm A, Bauer G et al (1983) Characterization of a foamy virus isolated from Cercopithecus aethiops lymphoblastoid cells. Med Microbiol Immunol 172:75-86
-
(1983)
Med Microbiol Immunol
, vol.172
, pp. 75-86
-
-
Neumann-Haefelin, D.1
Rethwilm, A.2
Bauer, G.3
-
18
-
-
0002929551
-
-
Ribonucleases H, Crouch, R.J., Toulme, J.J. (Eds Paris, France: INSERM
-
Kogoma, T., Foster, P.L. (1998) Physiological functions of E. coli RNase HI. In Ribonucleases H, Crouch, R.J., Toulme, J.J. (Eds), pp 39-66. Paris, France: INSERM
-
(1998)
Physiological Functions of E. Coli RNase HI
, pp. 39-66
-
-
Kogoma, T.1
Foster, P.L.2
-
19
-
-
0026056935
-
Mutations within the RNase H domain of HIV-1 reverse transcriptase abolish virus infectivity
-
Tisdale M, Schulze T, Larder BA et al (1991) Mutations within the RNase H domain of HIV-1 reverse transcriptase abolish virus infectivity. J Gen Virol 72:59-66
-
(1991)
J Gen Virol
, vol.72
, pp. 59-66
-
-
Tisdale, M.1
Schulze, T.2
Larder, B.A.3
-
20
-
-
69949105953
-
Reduction of gene expression by a hairpinloop structured oligodeoxynucleotide: Alternative to siRNA and antisense
-
Kwok T, Heinrich J, Jung-Shiu J et al (2009) Reduction of gene expression by a hairpinloop structured oligodeoxynucleotide: alternative to siRNA and antisense. Biochim Biophys Acta 1790:1170-1178
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1170-1178
-
-
Kwok, T.1
Heinrich, J.2
Jung-Shiu, J.3
-
21
-
-
2942525660
-
Binding, bending and bonding": Polypurine tractprimed initiation of plus-strand DNA synthesis in human immunodefi ciency virus
-
Rausch JW, Le Grice SF (2004) "Binding, bending and bonding": polypurine tractprimed initiation of plus-strand DNA synthesis in human immunodefi ciency virus. Int J Biochem Cell Biol 36:1752-1766
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1752-1766
-
-
Rausch, J.W.1
Le Grice, S.F.2
-
22
-
-
33646916634
-
Silencing of HIV by hairpin-loop-structured DNA oligonucleotide (siDNA
-
Moelling K, Abels S, Jendis J et al (2006) Silencing of HIV by hairpin-loop-structured DNA oligonucleotide (siDNA). FEBS Lett 580:3545-3550
-
(2006)
FEBS Lett
, vol.580
, pp. 3545-3550
-
-
Moelling, K.1
Abels, S.2
Jendis, J.3
-
23
-
-
58849139999
-
Oligonucleotide-mediated retroviral RNase H activation leads to reduced HIV-1 titer in patient-derived plasma
-
Heinrich J, Mathur S, Matskevich AA et al (2009) Oligonucleotide-mediated retroviral RNase H activation leads to reduced HIV-1 titer in patient-derived plasma. AIDS 23: 213-221
-
(2009)
AIDS
, vol.23
, pp. 213-221
-
-
Heinrich, J.1
Mathur, S.2
Matskevich, A.A.3
-
24
-
-
0032551544
-
Inhibition of replication of drug-resistant HIV type 1 isolates by polypurine tract-specifi c oligodeoxynucleotide TFO A
-
Jendis J, Strack B, Moelling K (1998) Inhibition of replication of drug-resistant HIV type 1 isolates by polypurine tract-specifi c oligodeoxynucleotide TFO A. AIDS Res Hum Retroviruses 14:999-1005
-
(1998)
AIDS Res Hum Retroviruses
, vol.14
, pp. 999-1005
-
-
Jendis, J.1
Strack, B.2
Moelling, K.3
-
25
-
-
33846215997
-
Short partially double-stranded oligodeoxynucleotide induces reverse transcriptase/RNase H-mediated cleavage of HIV RNA and contributes to abrogation of infectivity of virions
-
Matskevich AA, Ziogas A, Heinrich J et al (2006) Short partially double-stranded oligodeoxynucleotide induces reverse transcriptase/RNase H-mediated cleavage of HIV RNA and contributes to abrogation of infectivity of virions. AIDS Res Hum Retroviruses 22: 1220-1230
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, pp. 1220-1230
-
-
Matskevich, A.A.1
Ziogas, A.2
Heinrich, J.3
-
27
-
-
0036164420
-
The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides
-
ten Asbroek AL, van Groenigen M, Nooij M et al (2002) The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides. Eur J Biochem 269: 583-592
-
(2002)
Eur J Biochem
, vol.269
, pp. 583-592
-
-
Ten Asbroek, A.L.1
Van Groenigen, M.2
Nooij, M.3
-
28
-
-
33746522835
-
Mutations in genes encoding ribonucleases H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection
-
Crow YJ, Leitch A, Hayward BE et al (2006) Mutations in genes encoding ribonucleases H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection. Nat Genet 38:910-916
-
(2006)
Nat Genet
, vol.38
, pp. 910-916
-
-
Crow, Y.J.1
Leitch, A.2
Hayward, B.E.3
-
29
-
-
0345354684
-
Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice
-
Cerritelli SM, Frovola EG, Feng C et al (2003) Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice. Mol Cell 11:807-815
-
(2003)
Mol Cell
, vol.11
, pp. 807-815
-
-
Cerritelli, S.M.1
Frovola, E.G.2
Feng, C.3
-
30
-
-
0038275920
-
Translation repression by antisense sequences
-
Good L (2003) Translation repression by antisense sequences. Cell Mol Life Sci 60:854-861
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 854-861
-
-
Good, L.1
-
31
-
-
4444302947
-
Crystal structure of Argonaute and its implications for RISC slicer activity
-
Song JJ, Smith SK, Hannon GJ et al (2004) Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305: 1434-1437
-
(2004)
Science
, vol.305
, pp. 1434-1437
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
-
33
-
-
57749206034
-
Structure of an argonaute silencing complex with a seedcontaining guide DNA and target RNA duplex
-
Wang Y, Juranek S, Li H (2008) Structure of an argonaute silencing complex with a seedcontaining guide DNA and target RNA duplex. Nature 456:921-926
-
(2008)
Nature
, vol.456
, pp. 921-926
-
-
Wang, Y.1
Juranek, S.2
Li, H.3
-
34
-
-
79960189034
-
Synthesis, activity, and structural analysis of novel ?-hydroxytropolone inhibitors of human immunodefi ciency virus reverse transcriptaseassociated ribonuclease H
-
Chung S, Himmel DM, Jiang JK et al (2011) Synthesis, activity, and structural analysis of novel ?-hydroxytropolone inhibitors of human immunodefi ciency virus reverse transcriptaseassociated ribonuclease H. J Med Chem 54: 4462-4474
-
(2011)
J Med Chem
, vol.54
, pp. 4462-4474
-
-
Chung, S.1
Himmel, D.M.2
Jiang, J.K.3
-
35
-
-
0032425925
-
Mechanism of mitochondrial dysfunction and cytotoxicity induced by tropolones in isolated rat hepatocytes
-
Nakagawa Y, Tayama K (1998) Mechanism of mitochondrial dysfunction and cytotoxicity induced by tropolones in isolated rat hepatocytes. Chem Biol Interact 116:45-60
-
(1998)
Chem Biol Interact
, vol.116
, pp. 45-60
-
-
Nakagawa, Y.1
Tayama, K.2
-
36
-
-
10744226166
-
Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors
-
Klumpp K, Hang JQ, Rajendran S et al (2003) Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors. Nucleic Acids Res 31:6852-6859
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6852-6859
-
-
Klumpp, K.1
Hang, J.Q.2
Rajendran, S.3
-
37
-
-
0037474193
-
Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino) thien-2-yl]-2,4-dioxobutanoic acid
-
Shaw-Reid CA, Munshi V, Graham P et al (2003) Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino) thien-2-yl]-2,4- dioxobutanoic acid. J Biol Chem 278:2777-2780
-
(2003)
J Biol Chem
, vol.278
, pp. 2777-2780
-
-
Shaw-Reid, C.A.1
Munshi, V.2
Graham, P.3
-
38
-
-
20044387576
-
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones
-
Budihas SR, Gorshkova I, Gaidamakov S et al (2005) Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Nucleic Acids Res 33:1249-1256
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 1249-1256
-
-
Budihas, S.R.1
Gorshkova, I.2
Gaidamakov, S.3
-
39
-
-
58149160464
-
Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity
-
Wendeler M, Lee HF, Bermingham A et al (2008) Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity. ACS Chem Biol 3:635-644
-
(2008)
ACS Chem Biol
, vol.3
, pp. 635-644
-
-
Wendeler, M.1
Lee, H.F.2
Bermingham, A.3
-
40
-
-
77956131587
-
Structure-activity analysis of vinylogous urea inhibitors of human immunodefi ciency virusencoded ribonuclease H
-
Chung S, Wendeler M, Rausch JW et al (2010) Structure-activity analysis of vinylogous urea inhibitors of human immunodefi ciency virusencoded ribonuclease H. Antimicrob Agents Chemother 54:3913-3921
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3913-3921
-
-
Chung, S.1
Wendeler, M.2
Rausch, J.W.3
-
41
-
-
79956334444
-
Structural and binding analysis of pyrimidinol carboxylic acid and N-hydroxy quinazolinedione HIV-1 RNase H inhibitors
-
Lansdon EB, Liu Q, Leavitt SA et al (2011) Structural and binding analysis of pyrimidinol carboxylic acid and N-hydroxy quinazolinedione HIV-1 RNase H inhibitors. Antimicrob Agents Chemother 55:2905-2915
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2905-2915
-
-
Lansdon, E.B.1
Liu, Q.2
Leavitt, S.A.3
-
42
-
-
0036066508
-
SIRNA-directed inhibition of HIV-1 infection
-
Novina CD, Murray MF, Dykxhoorn DM et al (2002) siRNA-directed inhibition of HIV-1 infection. Nat Med 8:681-686
-
(2002)
Nat Med
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
Murray, M.F.2
Dykxhoorn, D.M.3
-
43
-
-
34250159115
-
RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides
-
Matzen K, Elzaouk L, Matskevich AA et al (2007) RNase H-mediated retrovirus destruction in vivo triggered by oligodeoxynucleotides. Nat Biotechnol 25:669-674
-
(2007)
Nat Biotechnol
, vol.25
, pp. 669-674
-
-
Matzen, K.1
Elzaouk, L.2
Matskevich, A.A.3
-
44
-
-
62049085212
-
Retroviral self-inactivation in the mouse vagina induced by short DNA
-
Wittmer-Elzaouk L, Jung-Shiu J, Heinrich J et al (2009) Retroviral self-inactivation in the mouse vagina induced by short DNA. Antiviral Res 82:22-28
-
(2009)
Antiviral Res
, vol.82
, pp. 22-28
-
-
Wittmer-Elzaouk, L.1
Jung-Shiu, J.2
Heinrich, J.3
-
45
-
-
84857921770
-
A short hairpin loop-structured oligodeoxynucleotide targeting the virion-associated RNase H of HIV inhibits HIV production in cell culture and in huPBL-SCID mice
-
Heinrich J, Schols D, Moelling K (2011) A short hairpin loop-structured oligodeoxynucleotide targeting the virion-associated RNase H of HIV inhibits HIV production in cell culture and in huPBL-SCID mice. Intervirology 55:242-246
-
(2011)
Intervirology
, vol.55
, pp. 242-246
-
-
Heinrich, J.1
Schols, D.2
Moelling, K.3
-
46
-
-
0141960926
-
Proteins and proteomics
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
-
Simpson, R.J. (2002) Proteins and Proteomics. A Laboratory Manual. p. 177. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
-
(2002)
A Laboratory Manual
, pp. 177
-
-
Simpson, R.J.1
-
47
-
-
0027322533
-
The interaction of illimaquinone, a selective inhibitor of the RNase H activity, with the reverse transcriptases of human immunodefi ciency and murine leukemia retroviruses
-
Loya S, Hizi A (1993) The interaction of illimaquinone, a selective inhibitor of the RNase H activity, with the reverse transcriptases of human immunodefi ciency and murine leukemia retroviruses. J Biol Chem 268: 9323-9328
-
(1993)
J Biol Chem
, vol.268
, pp. 9323-9328
-
-
Loya, S.1
Hizi, A.2
-
48
-
-
0027246189
-
The polypurine tract, PPT, of HIV as target for antisense and triple-helix-forming oligonucleotides
-
Volkmann S, Dannull J, Moelling K (1993) The polypurine tract, PPT, of HIV as target for antisense and triple-helix-forming oligonucleotides. Biochimie 75:71-78
-
(1993)
Biochimie
, vol.75
, pp. 71-78
-
-
Volkmann, S.1
Dannull, J.2
Moelling, K.3
|