A short hairpin loop-structured oligodeoxynucleotide targeting the virion-associated RNase H of HIV inhibits HIV production in cell culture and in huPBL-SCID mice

Intervirology

Volumn 55, Issue 3, 2012, Pages 242-246

  Heinrich, Jochen ^a   Schols, Dominique ^b   Moelling, Karin ^a,c  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

HIV; huPBL SCID mice; Oligodeoxynucleotide

Indexed keywords

FOSCARNET; OLIGODEOXYNUCLEOTIDE; RIBONUCLEASE H;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG EFFICACY; DRUG TARGETING; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEIC ACID STRUCTURE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCID MOUSE; SUPERNATANT; VIRION; VIRUS CULTURE; VIRUS INHIBITION; VIRUS MUTATION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; HIV INFECTIONS; HIV-1; HUMANS; MICE; MICE, SCID; OLIGODEOXYRIBONUCLEOTIDES; RIBONUCLEASE H, HUMAN IMMUNODEFICIENCY VIRUS; TREATMENT OUTCOME;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

EID: 84857921770     PISSN: 03005526     EISSN: 14230100     Source Type: Journal    
DOI: 10.1159/000324544     Document Type: Article

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