Mechanism of mitochondrial dysfunction and cytotoxicity induced by tropolones in isolated rat hepatocytes

Chemico-Biological Interactions

Volumn 116, Issue 1-2, 1998, Pages 45-60

  Nakagawa, Yoshio ^a   Tayama, Kuniaki ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Thujaplicin; Antimicrobial preservatives; Chelator; Cytotoxicity; Mitochondrial dysfunction; Rat hepatocytes; Tropolones

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE TRIPHOSPHATE; BUFFER; CALCIUM ION; CHELATING AGENT; EDETIC ACID; FLAVINE ADENINE NUCLEOTIDE; GLUTATHIONE; MAGNESIUM ION; MALIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVIC ACID; ROTENONE; SUCCINIC ACID; THIOL; TROPOLONE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CYTOTOXICITY; LIPID PEROXIDATION; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; RAT;

ANIMALS; CALCIUM; CATIONS, DIVALENT; CELLS, CULTURED; CHELATING AGENTS; DRUG INTERACTIONS; EDETIC ACID; IRON CHELATING AGENTS; LIVER; MAGNESIUM; MALE; MITOCHONDRIA, LIVER; MONOTERPENES; RATS; RATS, INBRED F344; TROPOLONE;

EID: 0032425925     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(98)00078-7     Document Type: Article

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