Evaluation of established human iPSC-derived neurons to model neurodegenerative diseases

Neuroscience

Volumn 301, Issue , 2015, Pages 204-212

  Meneghello, G ^a   Verheyen, A ^a   Van Ingen, M ^a   Kuijlaars, J ^b   Tuefferd, M ^a   Van Den Wyngaert, I ^a   Nuydens, R ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b HASSELT UNIVERSITY   (Belgium)

Author keywords

Disease modeling; GABAergic neuron; HiPSC; Neurodegeneration

Indexed keywords

CELL PROTEIN; GLUTAMATE DECARBOXYLASE 65; MAPT PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; NESTIN; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPSIN I; SYNAPTOPHYSIN; TUBB3 PROTEIN; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR GLUTAMATE TRANSPORTER 2; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; 4 AMINOBUTYRIC ACID RECEPTOR; CONDITIONED MEDIUM;

ANIMAL CELL; ARTICLE; CALCIUM IMAGING; CELL ACTIVITY; CELL CULTURE; CELL FUNCTION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; DEGENERATIVE DISEASE; GABAERGIC SYSTEM; GENE; HUMAN; HUMAN CELL; IMAGING; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; MAP2 GENE; MAPT GENE; MICROARRAY ANALYSIS; MOLECULAR MODEL; NERVE CELL; NERVE CELL DEGENERATION; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SLC17A6 GENE; SLC17A7 GENE; SYN1 GENE; TUBB3 GENE; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; ANIMAL; CONDITIONED MEDIUM; CYTOLOGY; DISEASE MODEL; EVALUATION STUDY; FOREBRAIN; GENE VECTOR; INDUCED PLURIPOTENT STEM CELL; LENTIVIRINAE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; GABAERGIC NEURONS; GENETIC VECTORS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LENTIVIRUS; MICROARRAY ANALYSIS; NEURODEGENERATIVE DISEASES; PROSENCEPHALON;

EID: 84931273730     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.05.071     Document Type: Article

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