A novel decoy that interrupts G93A-superoxide dismutase gain of interaction with malate dehydrogenase improves survival in an amyotrophic lateral sclerosis cell model

Journal of Medicinal Chemistry

Volumn 52, Issue 17, 2009, Pages 5442-5448

  Mali, Yael ^a   Zisapel, Nava ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBOXYTETRAMETHYLRHODAMINE DERIVATIVE; ADENOSINE TRIPHOSPHATE; ASPARTIC ACID; DECOY PEPTIDE; GLUCOSE; MALATE DEHYDROGENASE; MALIC ACID; PEPTIDE LIBRARY; POLYPEPTIDE; ROTENONE; SUPEROXIDE DISMUTASE; TETRAMETHYLRHODAMINE; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL SURVIVAL; CONTROLLED STUDY; DRUG SCREENING; HUMAN; INTRACELLULAR TRANSPORT; MOTONEURON; MOUSE; NERVE CELL; NONHUMAN; PROTEIN PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BASE SEQUENCE; CELL LINE; CELL SURVIVAL; DRUG DISCOVERY; GLUCOSE; HUMANS; IMMUNOPRECIPITATION; MALATE DEHYDROGENASE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; ROTENONE; SUPEROXIDE DISMUTASE;

EID: 69949083738     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900631m     Document Type: Article

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