Antigen-specific human monoclonal antibodies from transgenic mice

Methods in Molecular Biology

Volumn 1060, Issue , 2014, Pages 245-276

  Mompó, Susana Magadán ^a,b   González Fernández, África ^b  

^a UNIVERSITY OF VIGO   (Spain)

^b UNIVERSITY OF VIGO   (Spain)

Author keywords

Gene targeting; Human monoclonal antibodies; Immunoglobulin transgenes; Knockout mice; Transgenic mice; Transloci bearing human Ig genes; YAC based human Ig transloci

Indexed keywords

HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M; ANTIGEN; IMMUNOGLOBULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CLONING; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FREEZING; GENE LOCUS; GENE REARRANGEMENT; GENE SILENCING; GENE TARGETING; GENOME; HEAVY CHAIN; HYBRIDOMA; IMMUNIZATION; IMMUNOGLOBULIN GENE; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; LIGHT CHAIN; MYELOMA CELL; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; SCREENING; SPLEEN CELL; TRANSGENIC MOUSE; BONE MARROW TRANSPLANTATION; COMPLEMENT ACTIVATION; GENETIC VARIABILITY; GERM LINE; HEMATOPOIETIC CELL; HEMATOPOIETIC TISSUE; IMMUNOGENICITY; YEAST ARTIFICIAL CHROMOSOME;

ANIMALIA; MUS; MUS MUSCULUS;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIBODY SPECIFICITY; ANTIGENS; HUMANS; HYBRIDOMAS; MICE; MICE, TRANSGENIC; TRANSGENES;

EID: 84931262765     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-586-6_13     Document Type: Article

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