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Volumn , Issue , 2009, Pages 20-42

Immunogenicity assessment of antibody therapeutics

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EID: 84885619169     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511596773.005     Document Type: Chapter
Times cited : (2)

References (117)
  • 1
    • 0037367965 scopus 로고    scopus 로고
    • T-cell epitope mapping using the ELISPOT approach
    • Anthony DD and Lehmann PV. T-cell epitope mapping using the ELISPOT approach. Methods 2003; 29: 260-269.
    • (2003) Methods , vol.29 , pp. 260-269
    • Anthony, D.D.1    Lehmann, P.V.2
  • 4
    • 20444406448 scopus 로고    scopus 로고
    • Removal of therapeutic anti-lymphocyte antibodies from human sera prior to anti-human leukocyte antibody testing
    • Bearden CM, Book BK, Sidner RA, and Pescovitz MD. Removal of therapeutic anti-lymphocyte antibodies from human sera prior to anti-human leukocyte antibody testing. J Immunol Methods 2005; 300: 192-199.
    • (2005) J Immunol Methods , vol.300 , pp. 192-199
    • Bearden, C.M.1    Book, B.K.2    Sidner, R.A.3    Pescovitz, M.D.4
  • 6
    • 0035426018 scopus 로고    scopus 로고
    • Phase 1 evaluation of the respiratory syncytial virus-specific monoclonal antibody palivizumab in recipients of hematopoietic stem cell transplants
    • Boeckh M, Berrey MM, Bowden RA, Crawford SW, Balsley J, and Corey L. Phase 1 evaluation of the respiratory syncytial virus-specific monoclonal antibody palivizumab in recipients of hematopoietic stem cell transplants. J Infect Dis 2001; 184: 350-354.
    • (2001) J Infect Dis , vol.184 , pp. 350-354
    • Boeckh, M.1    Berrey, M.M.2    Bowden, R.A.3    Crawford, S.W.4    Balsley, J.5    Corey, L.6
  • 13
    • 0030806054 scopus 로고    scopus 로고
    • Antigen presentation by MHC class II molecules: Invariant chain function, protein trafficking, and the molecular basis of diverse determinant capture
    • Castellino F, Zhong G, and Germain RN. Antigen presentation by MHC class II molecules: invariant chain function, protein trafficking, and the molecular basis of diverse determinant capture. Hum Immunol 1997; 54: 159-169.
    • (1997) Hum Immunol , vol.54 , pp. 159-169
    • Castellino, F.1    Zhong, G.2    Germain, R.N.3
  • 14
    • 0026733449 scopus 로고
    • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
    • Chicz RM, Urban RG, Lane WS, Gorga JC, Stern LJ, Vignali DA, and Strominger JL. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. Nature 1992; 358: 764-768.
    • (1992) Nature , vol.358 , pp. 764-768
    • Chicz, R.M.1    Urban, R.G.2    Lane, W.S.3    Gorga, J.C.4    Stern, L.J.5    Vignali, D.A.6    Strominger, J.L.7
  • 15
    • 0031825917 scopus 로고    scopus 로고
    • The pharmacokinetics and human anti-mouse antibody response in rheumatoid arthritis patients treated with a chimeric anti-CD4 monoclonal antibody
    • Choy EHS, Schantz A, Pitzalis C, Kingsley GH, and Panayi GS. The pharmacokinetics and human anti-mouse antibody response in rheumatoid arthritis patients treated with a chimeric anti-CD4 monoclonal antibody. Br J Rheumatol 1998; 37: 801-802.
    • (1998) Br J Rheumatol , vol.37 , pp. 801-802
    • Choy, E.H.S.1    Schantz, A.2    Pitzalis, C.3    Kingsley, G.H.4    Panayi, G.S.5
  • 16
    • 0041854151 scopus 로고    scopus 로고
    • Safety, biodistribution, pharmacokinetics, and immunogenicity of 99mTc-labeled humanised monoclonal antibody BIWA 4 (bivatuzumab) in patients with squamous cell carcinoma of the head and neck
    • Colnot DR, Roos JC, de Bree R, Wilhelm AJ, Kummer JA, Hanft G, Heider KH, Stehle G, Snow GB, and van Dongen GA. Safety, biodistribution, pharmacokinetics, and immunogenicity of 99mTc-labeled humanised monoclonal antibody BIWA 4 (bivatuzumab) in patients with squamous cell carcinoma of the head and neck. Cancer Immunol Immunother 2003; 52: 576-582.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 576-582
    • Colnot, D.R.1    Roos, J.C.2    de Bree, R.3    Wilhelm, A.J.4    Kummer, J.A.5    Hanft, G.6    Heider, K.H.7    Stehle, G.8    Snow, G.B.9    van Dongen, G.A.10
  • 17
    • 0031041885 scopus 로고    scopus 로고
    • HLA Class I binding motifs derived from random peptide libraries differ at the COOH terminus from those of eluted peptides
    • Davenport MP, Smith KJ, Barouch D, Reid SW, Bodnar WM, Willis AC, Hunt DF, and Hill AV. HLA Class I binding motifs derived from random peptide libraries differ at the COOH terminus from those of eluted peptides. J Exp Med 1997; 185: 367-371.
    • (1997) J Exp Med , vol.185 , pp. 367-371
    • Davenport, M.P.1    Smith, K.J.2    Barouch, D.3    Reid, S.W.4    Bodnar, W.M.5    Willis, A.C.6    Hunt, D.F.7    Hill, A.V.8
  • 18
    • 3042697402 scopus 로고    scopus 로고
    • A novel predictive technique for the MHC class II peptide-binding interaction
    • Davies MN, Sansom CE, Beazley C, and Moss DS. A novel predictive technique for the MHC class II peptide-binding interaction. Mol Med 2003; 9: 220-225.
    • (2003) Mol Med , vol.9 , pp. 220-225
    • Davies, M.N.1    Sansom, C.E.2    Beazley, C.3    Moss, D.S.4
  • 19
    • 0023720148 scopus 로고
    • T-cell antigen receptor genes and T-cell recognition
    • Davis MM and Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature 1988; 334: 395-402.
    • (1988) Nature , vol.334 , pp. 395-402
    • Davis, M.M.1    Bjorkman, P.J.2
  • 24
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • Eng JK, McCormack AL, and Yates JR III. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom 1994; 5: 976-989.
    • (1994) J Am Soc Mass Spectrom , vol.5 , pp. 976-989
    • Eng, J.K.1    McCormack, A.L.2    Yates, J.R.3
  • 25
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • Falk K, Roetzschke O, Stefanovic S, Jung G, and Rammensee HG. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991; 351: 290-296.
    • (1991) Nature , vol.351 , pp. 290-296
    • Falk, K.1    Roetzschke, O.2    Stefanovic, S.3    Jung, G.4    Rammensee, H.G.5
  • 28
    • 0023038734 scopus 로고
    • OKT3 monoclonal antibody plasma levels during therapy and the subsequent development of host antibodies to OKT3
    • Goldstein G, Fuccello AJ, Norman DJ, Shield CF 3rd, Colvin RB, and Cosimi AB. OKT3 monoclonal antibody plasma levels during therapy and the subsequent development of host antibodies to OKT3. Transplantation 1986; 42: 507-511.
    • (1986) Transplantation , vol.42 , pp. 507-511
    • Goldstein, G.1    Fuccello, A.J.2    Norman, D.J.3    Shield, C.F.4    Colvin, R.B.5    Cosimi, A.B.6
  • 29
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon MS, Margolin K, Talpaz M, Sledge GW Jr, Holmgren E, Benjamin R, Stalter S, Shak S, and Adelman D. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 2001; 19: 843-850.
    • (2001) J Clin Oncol , vol.19 , pp. 843-850
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3    Sledge, G.W.4    Holmgren, E.5    Benjamin, R.6    Stalter, S.7    Shak, S.8    Adelman, D.9
  • 30
    • 0031576987 scopus 로고    scopus 로고
    • Two complementary methods for predicting peptides binding major histocompatibility complex molecules
    • Gulukota K, Sidney J, Sette A, and DeLisi C. Two complementary methods for predicting peptides binding major histocompatibility complex molecules. J Mol Biol 1997; 267: 1258-1267.
    • (1997) J Mol Biol , vol.267 , pp. 1258-1267
    • Gulukota, K.1    Sidney, J.2    Sette, A.3    DeLisi, C.4
  • 31
  • 32
    • 0027937713 scopus 로고
    • Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning
    • Hammer J, Bono E, Gallazzi F, Belunis C, Nagy Z, and Sinigaglia F. Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning. J Exp Med 1994; 180: 2353-2358.
    • (1994) J Exp Med , vol.180 , pp. 2353-2358
    • Hammer, J.1    Bono, E.2    Gallazzi, F.3    Belunis, C.4    Nagy, Z.5    Sinigaglia, F.6
  • 33
    • 0032848211 scopus 로고    scopus 로고
    • Review article: Safety of infliximab in clinical trials
    • Hanauer SB. Review article: safety of infliximab in clinical trials. Aliment Pharmacol Ther 1999; 13: 16-22.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 16-22
    • Hanauer, S.B.1
  • 36
    • 0037565441 scopus 로고    scopus 로고
    • CD4+ T cell epitope identification: Applications to allergy
    • Harding F. CD4+ T cell epitope identification: applications to allergy. Clin Exp Allergy 2003; 33: 557-565.
    • (2003) Clin Exp Allergy , vol.33 , pp. 557-565
    • Harding, F.1
  • 39
    • 17644378667 scopus 로고    scopus 로고
    • Immunogenicity of engineered antibodies
    • Hwang W and Foote J. Immunogenicity of engineered antibodies. Methods 2005; 36: 3-10.
    • (2005) Methods , vol.36 , pp. 3-10
    • Hwang, W.1    Foote, J.2
  • 43
    • 0033982749 scopus 로고    scopus 로고
    • Molecular remission induction with retinoic acid and anti-CD33 monoclonal antibody HuM195 in acute promyelocytic leukemia
    • Jurcic JG, DeBlasio T, Dumont L, Yao TJ, and Scheinberg DA. Molecular remission induction with retinoic acid and anti-CD33 monoclonal antibody HuM195 in acute promyelocytic leukemia. Clin Cancer Res 2000; 6: 372-380.
    • (2000) Clin Cancer Res , vol.6 , pp. 372-380
    • Jurcic, J.G.1    DeBlasio, T.2    Dumont, L.3    Yao, T.J.4    Scheinberg, D.A.5
  • 45
    • 2342658406 scopus 로고    scopus 로고
    • Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: A randomized, placebo-controlled, 52-week trial
    • Keystone EC, Kavanaugh AF, Sharp JT, Tannenbaum H, Hua Y, Teoh LS, Fischkoff SA, and Chartash EK. Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum 2004; 50: 1400-1411.
    • (2004) Arthritis Rheum , vol.50 , pp. 1400-1411
    • Keystone, E.C.1    Kavanaugh, A.F.2    Sharp, J.T.3    Tannenbaum, H.4    Hua, Y.5    Teoh, L.S.6    Fischkoff, S.A.7    Chartash, E.K.8
  • 46
    • 0142122694 scopus 로고    scopus 로고
    • From characterization of antibodies to prediction of immunogenicity
    • Koren, E. From characterization of antibodies to prediction of immunogenicity. Dev Biol 2002; 109: 87-95.
    • (2002) Dev Biol , vol.109 , pp. 87-95
    • Koren, E.1
  • 49
    • 0033452836 scopus 로고    scopus 로고
    • The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II molecules
    • Kropshofer H, Hämmerling GJ, and Vogt AB. The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II molecules. Immunol Rev 1999; 172: 267-278.
    • (1999) Immunol Rev , vol.172 , pp. 267-278
    • Kropshofer, H.1    Hämmerling, G.J.2    Vogt, A.B.3
  • 52
    • 0031660364 scopus 로고    scopus 로고
    • Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
    • Maini RN, Breedveld FC, Kalden JR, Smolen JS, Davis D, Macfarlane JD, Antoni C, Leeb B, Elliott MJ, Woody JN, et al. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 1998; 41:1552-1563.
    • (1998) Arthritis Rheum , vol.41 , pp. 1552-1563
    • Maini, R.N.1    Breedveld, F.C.2    Kalden, J.R.3    Smolen, J.S.4    Davis, D.5    Macfarlane, J.D.6    Antoni, C.7    Leeb, B.8    Elliott, M.J.9    Woody, J.N.10
  • 53
    • 0032387825 scopus 로고    scopus 로고
    • Predicting peptides that bind to MHC molecules using supervised learning of Hidden Markov Models
    • Mamitsuka H. Predicting peptides that bind to MHC molecules using supervised learning of Hidden Markov Models. Proteins 1998; 33: 460-474.
    • (1998) Proteins , vol.33 , pp. 460-474
    • Mamitsuka, H.1
  • 54
    • 0035253586 scopus 로고    scopus 로고
    • Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: Pharmacologic and long-term safety data
    • Margolin K, Gordon MS, Holmgren E, Gaudreault J, Novotny W, Fyfe G, Adelman D, Stalter S, and Breed J. Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data. J Clin Oncol 2001; 19: 851-856.
    • (2001) J Clin Oncol , vol.19 , pp. 851-856
    • Margolin, K.1    Gordon, M.S.2    Holmgren, E.3    Gaudreault, J.4    Novotny, W.5    Fyfe, G.6    Adelman, D.7    Stalter, S.8    Breed, J.9
  • 55
    • 0345352755 scopus 로고    scopus 로고
    • Bioinformatics tools for identifying class I-restricted epitopes
    • March
    • Martin W, Sbai H, and De Groot AS. Bioinformatics tools for identifying class I-restricted epitopes. Methods, March 2003, 29(3): 289-298.
    • (2003) Methods , vol.29 , Issue.3 , pp. 289-298
    • Martin, W.1    Sbai, H.2    De Groot, A.S.3
  • 57
    • 0036174635 scopus 로고    scopus 로고
    • Binding interactions between peptides and proteins of the class II major histocompatibility complex
    • McFarland BJ and Beeson C. Binding interactions between peptides and proteins of the class II major histocompatibility complex. Med Res Rev 2002; 22: 168-203.
    • (2002) Med Res Rev , vol.22 , pp. 168-203
    • McFarland, B.J.1    Beeson, C.2
  • 58
    • 0030008601 scopus 로고    scopus 로고
    • Detection of IGA anti-OKT3 antibodies in OKT3-treated transplant recipients
    • McIntyre JA, Kincade M, and Higgins NG. Detection of IGA anti-OKT3 antibodies in OKT3-treated transplant recipients. Transplantation 1996; 61: 1465-1469.
    • (1996) Transplantation , vol.61 , pp. 1465-1469
    • McIntyre, J.A.1    Kincade, M.2    Higgins, N.G.3
  • 59
    • 12444336904 scopus 로고    scopus 로고
    • Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis
    • Menter A, Gordon K, Carey W, Hamilton T, Glazer S, Caro I, Li N, and Gulliver W. Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis. Arch Dermatol 2005; 141: 31-38.
    • (2005) Arch Dermatol , vol.141 , pp. 31-38
    • Menter, A.1    Gordon, K.2    Carey, W.3    Hamilton, T.4    Glazer, S.5    Caro, I.6    Li, N.7    Gulliver, W.8
  • 62
    • 13244294176 scopus 로고    scopus 로고
    • Activation markers of peripheral blood mononuclear cells in late pregnancy and after delivery: A pilot study
    • Østensen M, Sicher P, Forger F, and Villiger PM. Activation markers of peripheral blood mononuclear cells in late pregnancy and after delivery: a pilot study. Ann Rheum Dis 2005; 64: 318-320.
    • (2005) Ann Rheum Dis , vol.64 , pp. 318-320
    • Østensen, M.1    Sicher, P.2    Forger, F.3    Villiger, P.M.4
  • 64
    • 24344448252 scopus 로고    scopus 로고
    • An acid dissociation bridging ELISA for detection of antibodies directed against therapeutic proteins in the presence of antigen
    • Patton A, Mullenix MC, Swanson SJ, and Koren E. An acid dissociation bridging ELISA for detection of antibodies directed against therapeutic proteins in the presence of antigen. J Immunol Methods 2005; 304: 189-195.
    • (2005) J Immunol Methods , vol.304 , pp. 189-195
    • Patton, A.1    Mullenix, M.C.2    Swanson, S.J.3    Koren, E.4
  • 65
    • 25444476693 scopus 로고    scopus 로고
    • Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method
    • Peters B and Sette A: Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method. BMC Bioinformatics 2005; 6:132.
    • (2005) BMC Bioinformatics , vol.6 , pp. 132
    • Peters, B.1    Sette, A.2
  • 66
    • 0141617555 scopus 로고    scopus 로고
    • Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules
    • Peters B, Tong W, Sidney J, Sette A, and Weng Z. Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules. Bioinformatics 2003; 19: 1765-1772.
    • (2003) Bioinformatics , vol.19 , pp. 1765-1772
    • Peters, B.1    Tong, W.2    Sidney, J.3    Sette, A.4    Weng, Z.5
  • 71
    • 5444249860 scopus 로고    scopus 로고
    • Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles
    • Reche PA, Glutting JP, Zhang H, and Reinherz EL. Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles. Immunogenetics 2004; 56: 405-419.
    • (2004) Immunogenetics , vol.56 , pp. 405-419
    • Reche, P.A.1    Glutting, J.P.2    Zhang, H.3    Reinherz, E.L.4
  • 72
    • 24644477106 scopus 로고    scopus 로고
    • A review of Campath in autoimmune disease: Biologic therapy in the gray zone between immunosuppression and immunoablation
    • Reiff A. A review of Campath in autoimmune disease: biologic therapy in the gray zone between immunosuppression and immunoablation. Hematology 2005; 10: 79-93.
    • (2005) Hematology , vol.10 , pp. 79-93
    • Reiff, A.1
  • 73
    • 0035884115 scopus 로고    scopus 로고
    • Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanised monoclonal antibody A33
    • Ritter G, Cohen LS, Williams C Jr, Richards EC, Old LJ, and Welt S. Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanised monoclonal antibody A33. Cancer Res 2001; 61: 6851-6859.
    • (2001) Cancer Res , vol.61 , pp. 6851-6859
    • Ritter, G.1    Cohen, L.S.2    Williams, C.3    Richards, E.C.4    Old, L.J.5    Welt, S.6
  • 74
    • 33748041958 scopus 로고    scopus 로고
    • Effects of protein aggregates: An immunologic perspective
    • Rosenberg AS. Effects of protein aggregates: an immunologic perspective. AAPS J 2006; 8: E501-E507.
    • (2006) AAPS J , vol.8 , pp. E501-E507
    • Rosenberg, A.S.1
  • 75
    • 9644287732 scopus 로고    scopus 로고
    • A risk-based approach to immunogenicity concerns of therapeutic protein products - Part 1 - considering consequences of the immune response to a protein
    • Rosenberg AS and Worobec A. A risk-based approach to immunogenicity concerns of therapeutic protein products - Part 1 - considering consequences of the immune response to a protein. Biopharm Int 2004a; 17: 22-26.
    • (2004) Biopharm Int , vol.17 , pp. 22-26
    • Rosenberg, A.S.1    Worobec, A.2
  • 76
    • 10944231251 scopus 로고    scopus 로고
    • A risk-based approach to immunogenicity concerns of therapeutic protein products - Part 2 - considering host-specific and product-specific factors impacting immunogenicity
    • Rosenberg AS and Worobec A. A risk-based approach to immunogenicity concerns of therapeutic protein products - Part 2 - considering host-specific and product-specific factors impacting immunogenicity. Biopharm Int 2004b; 17: 34-42.
    • (2004) Biopharm Int , vol.17 , pp. 34-42
    • Rosenberg, A.S.1    Worobec, A.2
  • 77
    • 16844367771 scopus 로고    scopus 로고
    • A risk-based approach to immunogenicity concerns of therapeutic protein products - Part 3 - effects of manufacturing changes in immunogenicity and the utility of animal immunogenicity studies
    • Rosenberg AS and Worobec A. A risk-based approach to immunogenicity concerns of therapeutic protein products - Part 3 - effects of manufacturing changes in immunogenicity and the utility of animal immunogenicity studies. Biopharm Int 2005; 18: 32-36.
    • (2005) Biopharm Int , vol.18 , pp. 32-36
    • Rosenberg, A.S.1    Worobec, A.2
  • 79
    • 0035288013 scopus 로고    scopus 로고
    • Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7
    • Rudolf MP, Man S, Melief CJM, Sette A, and Kast WM. Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7. Clin Cancer Res 2001; 7: 788s-795s.
    • (2001) Clin Cancer Res , vol.7 , pp. 788s-795s
    • Rudolf, M.P.1    Man, S.2    Melief, C.J.M.3    Sette, A.4    Kast, W.M.5
  • 82
    • 34247890107 scopus 로고    scopus 로고
    • Pharmacokinetics, immunogenicity and safety of bivatuzumab mertansine, a novel CD44v6-targeting immunoconjugate, in patients with squamous cell carcinoma of the head and neck
    • Sauter A, Kloft C, Gronau S, Bogeschdorfer F, Erhardt T, Golze W, Schroen C, Staab A, Riechelmann H, and Hoermann K. Pharmacokinetics, immunogenicity and safety of bivatuzumab mertansine, a novel CD44v6-targeting immunoconjugate, in patients with squamous cell carcinoma of the head and neck. Int J Oncol 2007; 30: 927-935.
    • (2007) Int J Oncol , vol.30 , pp. 927-935
    • Sauter, A.1    Kloft, C.2    Gronau, S.3    Bogeschdorfer, F.4    Erhardt, T.5    Golze, W.6    Schroen, C.7    Staab, A.8    Riechelmann, H.9    Hoermann, K.10
  • 87
    • 27144522470 scopus 로고    scopus 로고
    • A phase I trial of humanized monoclonal antibody A33 in patients with colorectal carcinoma: Biodistribution, pharmacokinetics, and quantitative tumor uptake
    • Scott AM, Lee FT, Jones R, Hopkins W, MacGregor D, Cebon JS, Hannah A, Chong G, U P, Papenfuss A, et al. A phase I trial of humanized monoclonal antibody A33 in patients with colorectal carcinoma: biodistribution, pharmacokinetics, and quantitative tumor uptake. Clin Cancer Res 2005; 11:4810-4817.
    • (2005) Clin Cancer Res , vol.11 , pp. 4810-4817
    • Scott, A.M.1    Lee, F.T.2    Jones, R.3    Hopkins, W.4    MacGregor, D.5    Cebon, J.S.6    Hannah, A.7    Chong, G.8    Papenfuss, A.9
  • 88
    • 0035009714 scopus 로고    scopus 로고
    • Relating amino acid sequence to phenotype: Analysis of peptide-binding data
    • Segal MR, Cummings MP, and Hubbard AE. Relating amino acid sequence to phenotype: analysis of peptide-binding data. Biometrics 2001; 57: 632-642.
    • (2001) Biometrics , vol.57 , pp. 632-642
    • Segal, M.R.1    Cummings, M.P.2    Hubbard, A.E.3
  • 91
    • 0036137241 scopus 로고    scopus 로고
    • ProPred: Prediction of HLA-DR binding sites
    • Singh H and Raghava GP. ProPred: prediction of HLA-DR binding sites. Bioinformatics 2001; 17: 1236-1237.
    • (2001) Bioinformatics , vol.17 , pp. 1236-1237
    • Singh, H.1    Raghava, G.P.2
  • 102
    • 0031683919 scopus 로고    scopus 로고
    • Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants
    • The Impact-RSV Study Group. Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. Pediatrics 2006; 102:531-537.
    • (2006) Pediatrics , vol.102 , pp. 531-537
  • 103
    • 33750685640 scopus 로고    scopus 로고
    • A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus
    • Tijink BM, Buter J, de Bree R, Giaccone G, Lang MS, Staab A, Leemans CR, van Dongen GA. A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus. Clin Cancer Res 2006; 12: 6064-6072.
    • (2006) Clin Cancer Res , vol.12 , pp. 6064-6072
    • Tijink, B.M.1    Buter, J.2    de Bree, R.3    Giaccone, G.4    Lang, M.S.5    Staab, A.6    Leemans, C.R.7    van Dongen, G.A.8
  • 104
    • 0037440038 scopus 로고    scopus 로고
    • Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: A phase I, pharmacokinetic, and biologic correlative study
    • Tolcher AW, Ochoa L, Hammond LA, Patnaik A, Edwards T, Takimoto C, Smith L, de Bono J, Schwartz G, Mays T, et al. Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: a phase I, pharmacokinetic, and biologic correlative study. J Clin Oncol 2003; 21:211-222.
    • (2003) J Clin Oncol , vol.21 , pp. 211-222
    • Tolcher, A.W.1    Ochoa, L.2    Hammond, L.A.3    Patnaik, A.4    Edwards, T.5    Takimoto, C.6    Smith, L.7    de Bono, J.8    Schwartz, G.9    Mays, T.10
  • 105
    • 0033387144 scopus 로고    scopus 로고
    • Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosisinducing CD19-directed tyrosine kinase inhibitor
    • Uckun FM, Messinger Y, Chen CL, O'Neill K, Myers DE, Goldman F, Hurvitz C, Casper JT, and Levine A. Treatment of therapy-refractory B-lineage acute lymphoblastic leukemia with an apoptosisinducing CD19-directed tyrosine kinase inhibitor. Clin Cancer Res 1999; 5: 3906-3913.
    • (1999) Clin Cancer Res , vol.5 , pp. 3906-3913
    • Uckun, F.M.1    Messinger, Y.2    Chen, C.L.3    O'Neill, K.4    Myers, D.E.5    Goldman, F.6    Hurvitz, C.7    Casper, J.T.8    Levine, A.9
  • 107
    • 11144355274 scopus 로고    scopus 로고
    • Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed
    • van de Putte LB, Atkins C, Malaise M, Sany J, Russell AS, van Riel PL, Settas L, Bijlsma JW, Todesco S, Dougados M, et al. Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed. Ann Rheum Dis 2004; 63:508-516.
    • (2004) Ann Rheum Dis , vol.63 , pp. 508-516
    • van de Putte, L.B.1    Atkins, C.2    Malaise, M.3    Sany, J.4    Russell, A.S.5    van Riel, P.L.6    Settas, L.7    Bijlsma, J.W.8    Todesco, S.9    Dougados, M.10
  • 109
    • 34548130215 scopus 로고    scopus 로고
    • Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease
    • Vermeire S, Noman M, Van Assche G, Baert F, D'Haens G, and Rutgeerts P. Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease. Gut 2007; 56: 1226-1231.
    • (2007) Gut , vol.56 , pp. 1226-1231
    • Vermeire, S.1    Noman, M.2    Van Assche, G.3    Baert, F.4    D'Haens, G.5    Rutgeerts, P.6
  • 113
    • 0037231533 scopus 로고    scopus 로고
    • Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
    • Weinblatt ME, Keystone EC, Furst DE, Moreland LW, Weisman MH, Birbara CA, Teoh LA, Fischkoff SA, and Chartash EK. Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum 2003; 48: 35-45.
    • (2003) Arthritis Rheum , vol.48 , pp. 35-45
    • Weinblatt, M.E.1    Keystone, E.C.2    Furst, D.E.3    Moreland, L.W.4    Weisman, M.H.5    Birbara, C.A.6    Teoh, L.A.7    Fischkoff, S.A.8    Chartash, E.K.9
  • 115
    • 0037386871 scopus 로고    scopus 로고
    • Preliminary report of a phase I study of combination chemotherapy and humanized A33 antibody immunotherapy in patients with advanced colorectal cancer
    • Welt S, Ritter G, Williams C Jr, Cohen LS, Jungbluth A, Richards EA, Old LJ, and Kemeny NE. Preliminary report of a phase I study of combination chemotherapy and humanized A33 antibody immunotherapy in patients with advanced colorectal cancer. Clin Cancer Res 2003b; 9: 1347-1353.
    • (2003) Clin Cancer Res , vol.9 , pp. 1347-1353
    • Welt, S.1    Ritter, G.2    Williams, C.3    Cohen, L.S.4    Jungbluth, A.5    Richards, E.A.6    Old, L.J.7    Kemeny, N.E.8
  • 116
    • 0142148183 scopus 로고    scopus 로고
    • Application of support vector machines for T-cell epitopes prediction
    • Zhao Y, Pinilla C, Valmori D, Martin R, and Simon R. Application of support vector machines for T-cell epitopes prediction. Bioinformatics 2003; 19: 1978-1984.
    • (2003) Bioinformatics , vol.19 , pp. 1978-1984
    • Zhao, Y.1    Pinilla, C.2    Valmori, D.3    Martin, R.4    Simon, R.5
  • 117
    • 0029961746 scopus 로고    scopus 로고
    • CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells
    • Zhou LJ and Tedder TF. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci USA 1996; 93: 2588-2592.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2588-2592
    • Zhou, L.J.1    Tedder, T.F.2


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