PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors

Cell Death and Differentiation

Volumn 22, Issue 7, 2015, Pages 1144-1157

  Farres J ^a   Llacuna, L ^a   Martin Caballero, J ^b   Martinez C ^c   Lozano, J J ^c   Ampurdanes C ^a   Lopez Contreras A J ^d   Florensa, L ^a   Navarro, J ^a   Ottina, E ^e   Dantzer, F ^f   Schreiber, V ^f   Villunger, A ^e   Fernandez Capetillo O ^d   Yelamos J ^a,c  

^a HOSPITAL DEL MAR   (Spain)

^b Barcelona Biomedical Research Park   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d Structural Biology and Biocomputing Programme   (Spain)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^f Institut de Recherche de l'Ecole de Biotechnologie de Strasbourg   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR; HEMOGLOBIN; HISTONE H2AX; HISTONE H2AX GAMMA; IRON; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; P21 ACTIVATED KINASE; PROTEIN P53; PUMA PROTEIN; REPLICATION FACTOR A; TRANSCRIPTOME; UNCLASSIFIED DRUG; H2AFX PROTEIN, MOUSE; HISTONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP2 PROTEIN, MOUSE;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE S PHASE; CELL DEATH; CELL DIFFERENTIATION; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; DISEASE EXACERBATION; DNA DAMAGE CHECKPOINT; DNA REPAIR; EMBRYO; ENZYME ACTIVATION; ERYTHROCYTE VOLUME; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; FETUS LIVER; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GENE AMPLIFICATION; GENE FUNCTION; GENOMIC INSTABILITY; HEMATOCRIT; HEMATOPOIETIC STEM CELL; HEMOGLOBIN BLOOD LEVEL; HEMOLYSIS; IMMUNOFLUORESCENCE MICROSCOPY; IRON BLOOD LEVEL; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MICRONUCLEUS; MOUSE; NONHUMAN; PERINATAL DEATH; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; STEADY STATE; UPREGULATION; ANIMAL; APOPTOSIS; DNA REPLICATION; GENE DELETION; GENETICS; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

MUS;

ANIMALS; APOPTOSIS; DNA REPLICATION; ERYTHROID PRECURSOR CELLS; ERYTHROPOIESIS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE DELETION; HISTONES; MICE; POLY(ADP-RIBOSE) POLYMERASES; STRESS, PHYSIOLOGICAL;

EID: 84930764291     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.202     Document Type: Article

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