-
2
-
-
77951023118
-
Toward a unified nomenclature for mammalian ADPribosyltransferases
-
Hottiger MO, Hassa PO, Luscher B, Schuler H, Koch-Nolte F (2010) Toward a unified nomenclature for mammalian ADPribosyltransferases. Trends Biochem Sci 35:208-219
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 208-219
-
-
Hottiger, M.O.1
Hassa, P.O.2
Luscher, B.3
Schuler, H.4
Koch-Nolte, F.5
-
3
-
-
0021156965
-
Quantification of in vivo levels of poly(ADP-ribose): Tritium labeling method and radioimmunoassay
-
Miwa M, Sugimura T (1984) Quantification of in vivo levels of poly(ADP-ribose): tritium labeling method and radioimmunoassay. Methods Enzymol 106:495-500
-
(1984)
Methods Enzymol
, vol.106
, pp. 495-500
-
-
Miwa, M.1
Sugimura, T.2
-
4
-
-
0021119146
-
Structure of poly(ADP-ribose)
-
Miwa M, Sugimura T (1984) Structure of poly(ADP-ribose). Methods Enzymol 106:441-450
-
(1984)
Methods Enzymol
, vol.106
, pp. 441-450
-
-
Miwa, M.1
Sugimura, T.2
-
5
-
-
0021997074
-
Poly(ADP-ribose) in the cellular response to DNA damage
-
Berger NA (1985) Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 101:4-15
-
(1985)
Radiat Res
, vol.101
, pp. 4-15
-
-
Berger, N.A.1
-
7
-
-
53149094334
-
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation
-
Kleine H, Poreba E, Lesniewicz K, Hassa PO, Hottiger MO, Litchfield DW, Shilton BH, Luscher B (2008) Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol Cell 32:57-69
-
(2008)
Mol Cell
, vol.32
, pp. 57-69
-
-
Kleine, H.1
Poreba, E.2
Lesniewicz, K.3
Hassa, P.O.4
Hottiger, M.O.5
Litchfield, D.W.6
Shilton, B.H.7
Luscher, B.8
-
8
-
-
0033580856
-
PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase
-
Ame JC, Rolli V, Schreiber V, Niedergang C, Apiou F, Decker P, Muller S, Hoger T, Menissier-de Murcia J, de Murcia G (1999) PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase. J Biol Chem 274:17860-17868
-
(1999)
J Biol Chem
, vol.274
, pp. 17860-17868
-
-
Ame, J.C.1
Rolli, V.2
Schreiber, V.3
Niedergang, C.4
Apiou, F.5
Decker, P.6
Muller, S.7
Hoger, T.8
Menissier-De Murcia, J.9
De Murcia, G.10
-
9
-
-
78650756134
-
PARP-3 and APLF function together to accelerate nonhomologous endjoining
-
Rulten SL, Fisher AE, Robert I, Zuma MC, Rouleau M, Ju L, Poirier G, Reina-San-Martin B, Caldecott KW (2011) PARP-3 and APLF function together to accelerate nonhomologous endjoining. Mol Cell 41:33-45
-
(2011)
Mol Cell
, vol.41
, pp. 33-45
-
-
Rulten, S.L.1
Fisher, A.E.2
Robert, I.3
Zuma, M.C.4
Rouleau, M.5
Ju, L.6
Poirier, G.7
Reina-San-Martin, B.8
Caldecott, K.W.9
-
10
-
-
79952599748
-
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
-
Boehler C, Gauthier LR, Mortusewicz O, Biard DS, Saliou JM, Bresson A, Sanglier-Cianferani S, Smith S, Schreiber V, Boussin F, Dantzer F (2011) Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc Natl Acad Sci USA 108:2783-2788
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2783-2788
-
-
Boehler, C.1
Gauthier, L.R.2
Mortusewicz, O.3
Biard, D.S.4
Saliou, J.M.5
Bresson, A.6
Sanglier-Cianferani, S.7
Smith, S.8
Schreiber, V.9
Boussin, F.10
Dantzer, F.11
-
11
-
-
0024456894
-
Zinc-binding domain of poly(ADPribose) polymerase participates in the recognition of single strand breaks on DNA
-
Menissier-de Murcia J, Molinete M, Gradwohl G, Simonin F, de Murcia G (1989) Zinc-binding domain of poly(ADPribose) polymerase participates in the recognition of single strand breaks on DNA. J Mol Biol 210:229-233
-
(1989)
J Mol Biol
, vol.210
, pp. 229-233
-
-
Menissier-De Murcia, J.1
Molinete, M.2
Gradwohl, G.3
Simonin, F.4
De Murcia, G.5
-
12
-
-
0035815662
-
A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. Structure and expression of the mouse PARP-2 gene
-
Ame JC, Schreiber V, Fraulob V, Dolle P, de Murcia G, Niedergang CP (2001) A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. Structure and expression of the mouse PARP-2 gene. J Biol Chem 276:11092-11099
-
(2001)
J Biol Chem
, vol.276
, pp. 11092-11099
-
-
Ame, J.C.1
Schreiber, V.2
Fraulob, V.3
Dolle, P.4
De Murcia, G.5
Niedergang, C.P.6
-
13
-
-
84870672512
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Homo Sapiens] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Homo sapiens] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/10038. Accessed 17 April 2012
-
(2012)
-
-
-
14
-
-
84870680993
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Pan Troglodytes] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Pan troglodytes] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/465197. Accessed 17 April 2012
-
(2012)
-
-
-
15
-
-
84870701156
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Nomascus Leucogenys] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Nomascus leucogenys] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100591855. Accessed 17 April 2012
-
(2012)
-
-
-
16
-
-
84870715326
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Pongo Abelii] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Pongo abelii] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100452137. Accessed 17 April 2012
-
(2012)
-
-
-
17
-
-
0034920278
-
Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis
-
Doucet-Chabeaud G, Godon C, Brutesco C, de Murcia G, Kazmaier M (2001) Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis. Mol Genet Genomics 265:954-963
-
(2001)
Mol Genet Genomics
, vol.265
, pp. 954-963
-
-
Doucet-Chabeaud, G.1
Godon, C.2
Brutesco, C.3
De Murcia, G.4
Kazmaier, M.5
-
18
-
-
0037151051
-
Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1
-
Schreiber V, Ame JC, Dolle P, Schultz I, Rinaldi B, Fraulob V, Menissier-de Murcia J, de Murcia G (2002) Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. J Biol Chem 277:23028-23036
-
(2002)
J Biol Chem
, vol.277
, pp. 23028-23036
-
-
Schreiber, V.1
Ame, J.C.2
Dolle, P.3
Schultz, I.4
Rinaldi, B.5
Fraulob, V.6
Menissier-De Murcia, J.7
De Murcia, G.8
-
19
-
-
0033135769
-
A human poly(ADP-ribose) polymerase gene family (ADPRTL): CDNA cloning of two novel poly(ADPribose) polymerase homologues
-
Johansson M (1999) A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADPribose) polymerase homologues. G. Genomics 57:442-445
-
(1999)
G. Genomics
, vol.57
, pp. 442-445
-
-
Johansson, M.1
-
20
-
-
3242891383
-
PARP-1, PARP-2 and ATM in the DNA damage response: Functional synergy in mouse development
-
Huber A, Bai P, Menissier-de Murcia J, de Murcia G (2004)PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development. DNA Repair (Amst) 3:1103-1108
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1103-1108
-
-
Huber, A.1
Bai, P.2
Menissier-De Murcia, J.3
De Murcia, G.4
-
21
-
-
48949084229
-
Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS
-
Haenni SS, Altmeyer M, Hassa PO, Valovka T, Fey M, Hottiger MO (2008) Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS. BMC Cell Biol 9:39
-
(2008)
BMC Cell Biol
, vol.9
, pp. 39
-
-
Haenni, S.S.1
Altmeyer, M.2
Hassa, P.O.3
Valovka, T.4
Fey, M.5
Hottiger, M.O.6
-
22
-
-
14044273481
-
PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli
-
Meder VS, Boeglin M, de Murcia G, Schreiber V (2005)PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli. J Cell Sci 118:211-222
-
(2005)
J Cell Sci
, vol.118
, pp. 211-222
-
-
Meder, V.S.1
Boeglin, M.2
De Murcia, G.3
Schreiber, V.4
-
23
-
-
0038219534
-
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse
-
Menissier-de Murcia J, Ricoul M, Tartier L, Niedergang C, Huber A, Dantzer F, Schreiber V, Ame JC, Dierich A, LeMeur M, Sabatier L, Chambon P, de Murcia G (2003) Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. EMBO J 22:2255-2263
-
(2003)
EMBO J
, vol.22
, pp. 2255-2263
-
-
Menissier-De Murcia, J.1
Ricoul, M.2
Tartier, L.3
Niedergang, C.4
Huber, A.5
Dantzer, F.6
Schreiber, V.7
Ame, J.C.8
Dierich, A.9
Lemeur, M.10
Sabatier, L.11
Chambon, P.12
De Murcia, G.13
-
24
-
-
41549155890
-
Toward specific functions of poly(ADP-ribose) polymerase-2
-
Yelamos J, Schreiber V, Dantzer F (2008) Toward specific functions of poly(ADP-ribose) polymerase-2. Trends Mol Med 14:169-178
-
(2008)
Trends Mol Med
, vol.14
, pp. 169-178
-
-
Yelamos, J.1
Schreiber, V.2
Dantzer, F.3
-
25
-
-
38049049312
-
PARP-2: Structure-function relationship
-
Burkle A (ed), Springer, New York
-
Schreiber V, Ricoul M, Amé JC, Dantzer F, Meder VS, Spenlehauer C, Stiegler P, Niedergang C, Sabatier L, Favaudon V, Ménissier-de Murcia J, de Murcia G (2004)PARP-2: structure-function relationship. In: Burkle A (ed) Poly(ADP-ribosyl)ation, Springer, New York, pp 13-31
-
(2004)
Poly(ADP-ribosyl)ation
, pp. 13-31
-
-
Schreiber, V.1
Ricoul, M.2
Amé, J.C.3
Dantzer, F.4
Meder, V.S.5
Spenlehauer, C.6
Stiegler, P.7
Niedergang, C.8
Sabatier, L.9
Favaudon, V.10
Ménissier-De Murcia, J.11
De Murcia, G.12
-
26
-
-
48949116207
-
Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation
-
Haenni SS, Hassa PO, Altmeyer M, Fey M, Imhof R, Hottiger MO (2008) Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation. Int J Biochem Cell Biol 40:2274-2283
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 2274-2283
-
-
Haenni, S.S.1
Hassa, P.O.2
Altmeyer, M.3
Fey, M.4
Imhof, R.5
Hottiger, M.O.6
-
27
-
-
67649888368
-
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
-
Altmeyer M, Messner S, Hassa PO, Fey M, Hottiger MO (2009)Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res 37:3723-3738
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 3723-3738
-
-
Altmeyer, M.1
Messner, S.2
Hassa, P.O.3
Fey, M.4
Hottiger, M.O.5
-
28
-
-
77950669700
-
Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry
-
Isabelle M, Moreel X, Gagne JP, Rouleau M, Ethier C, Gagne P, Hendzel MJ, Poirier GG (2010) Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry. Proteome Sci 8:22
-
(2010)
Proteome Sci
, vol.8
, pp. 22
-
-
Isabelle, M.1
Moreel, X.2
Gagne, J.P.3
Rouleau, M.4
Ethier, C.5
Gagne, P.6
Hendzel, M.J.7
Poirier, G.G.8
-
29
-
-
0037072929
-
Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2
-
Benchoua A, Couriaud C, Guegan C, Tartier L, Couvert P, Friocourt G, Chelly J, Menissier-de MJ, Onteniente B (2002) Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2. J Biol Chem 277:34217-34222
-
(2002)
J Biol Chem
, vol.277
, pp. 34217-34222
-
-
Benchoua, A.1
Couriaud, C.2
Guegan, C.3
Tartier, L.4
Couvert, P.5
Friocourt, G.6
Chelly, J.7
Menissier-De, M.J.8
Onteniente, B.9
-
30
-
-
1342286058
-
Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2
-
Oliver AW, Ame JC, Roe SM, Good V, de Murcia G, Pearl LH (2004)Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2. Nucleic Acids Res 32:456-464
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 456-464
-
-
Oliver, A.W.1
Ame, J.C.2
Roe, S.M.3
Good, V.4
De Murcia, G.5
Pearl, L.H.6
-
31
-
-
76749153013
-
Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888
-
Karlberg T, Hammarstrom M, Schutz P, Svensson L, Schuler H (2010) Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry 49:1056-1058
-
(2010)
Biochemistry
, vol.49
, pp. 1056-1058
-
-
Karlberg, T.1
Hammarstrom, M.2
Schutz, P.3
Svensson, L.4
Schuler, H.5
-
32
-
-
0032515152
-
Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers
-
Shieh WM, Ame JC, Wilson MV, Wang ZQ, Koh DW, Jacobson MK, Jacobson EL (1998) Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers. J Biol Chem 273:30069-30072
-
(1998)
J Biol Chem
, vol.273
, pp. 30069-30072
-
-
Shieh, W.M.1
Ame, J.C.2
Wilson, M.V.3
Wang, Z.Q.4
Koh, D.W.5
Jacobson, M.K.6
Jacobson, E.L.7
-
33
-
-
81055125040
-
Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction
-
Szanto M, Rutkai I, Hegedus C, Czikora A, Rozsahegyi M, Kiss B, Virag L, Gergely P, Toth A, Bai P (2011) Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction. Cardiovasc Res 92:430-438
-
(2011)
Cardiovasc Res
, vol.92
, pp. 430-438
-
-
Szanto, M.1
Rutkai, I.2
Hegedus, C.3
Czikora, A.4
Rozsahegyi, M.5
Kiss, B.6
Virag, L.7
Gergely, P.8
Toth, A.9
Bai, P.10
-
34
-
-
80052961045
-
Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays
-
Troiani S, Lupi R, Perego R, Re Depaolini S, Thieffine S, Bosotti R, Rusconi L (2011) Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays. FEBS J 278:3676-3687
-
(2011)
FEBS J
, vol.278
, pp. 3676-3687
-
-
Troiani, S.1
Lupi, R.2
Perego, R.3
Re Depaolini, S.4
Thieffine, S.5
Bosotti, R.6
Rusconi, L.7
-
35
-
-
0942300650
-
PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation
-
Chalmers A, Johnston P, Woodcock M, Joiner M, Marples B (2004)PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation. Int J Radiat Oncol Biol Phys 58:410-419
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 410-419
-
-
Chalmers, A.1
Johnston, P.2
Woodcock, M.3
Joiner, M.4
Marples, B.5
-
36
-
-
38049007502
-
Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
-
Mortusewicz O, Ame JC, Schreiber V, Leonhardt H (2007) Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res 35:7665-7675
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7665-7675
-
-
Mortusewicz, O.1
Ame, J.C.2
Schreiber, V.3
Leonhardt, H.4
-
37
-
-
69849097500
-
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination
-
Bryant HE, Petermann E, Schultz N, Jemth AS, Loseva O, Issaeva N, Johansson F, Fernandez S, McGlynn P, Helleday T (2009)PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination. EMBO J 28:2601-2615
-
(2009)
EMBO J
, vol.28
, pp. 2601-2615
-
-
Bryant, H.E.1
Petermann, E.2
Schultz, N.3
Jemth, A.S.4
Loseva, O.5
Issaeva, N.6
Johansson, F.7
Fernandez, S.8
McGlynn, P.9
Helleday, T.10
-
38
-
-
77952426818
-
Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice
-
Nicolas L, Martinez C, Baro C, Rodriguez M, Baroja-Mazo A, Sole F, Flores JM, Ampurdanes C, Dantzer F, Martin-Caballero J, Aparicio P, Yelamos J (2010) Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice. Oncogene 29:2877-2883
-
(2010)
Oncogene
, vol.29
, pp. 2877-2883
-
-
Nicolas, L.1
Martinez, C.2
Baro, C.3
Rodriguez, M.4
Baroja-Mazo, A.5
Sole, F.6
Flores, J.M.7
Ampurdanes, C.8
Dantzer, F.9
Martin-Caballero, J.10
Aparicio, P.11
Yelamos, J.12
-
39
-
-
66049143898
-
Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination
-
Robert I, Dantzer F, Reina-San-Martin B (2009)Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination. J Exp Med 206:1047-1056
-
(2009)
J Exp Med
, vol.206
, pp. 1047-1056
-
-
Robert, I.1
Dantzer, F.2
Reina-San-Martin, B.3
-
40
-
-
1242339684
-
Poly(ADP-ribose) reactivates stalled DNA topoisomerase i and Induces DNA strand break resealing
-
Malanga M, Althaus FR (2004)Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing. J Biol Chem 279:5244-5248
-
(2004)
J Biol Chem
, vol.279
, pp. 5244-5248
-
-
Malanga, M.1
Althaus, F.R.2
-
41
-
-
78449271062
-
Mitomycin C modulates DNA-double strand break repair genes in cervical carcinoma cells
-
Kang YH, Lee KA, Kim JH, Park SG, Yoon DY (2010) Mitomycin C modulates DNA-double strand break repair genes in cervical carcinoma cells. Amino Acids 39:1291-1298
-
(2010)
Amino Acids
, vol.39
, pp. 1291-1298
-
-
Kang, Y.H.1
Lee, K.A.2
Kim, J.H.3
Park, S.G.4
Yoon, D.Y.5
-
42
-
-
10744233161
-
Functional interaction between poly(ADPRibose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2
-
Dantzer F, Giraud-Panis MJ, Jaco I, Ame JC, Schultz I, Blasco M, Koering CE, Gilson E, Menissier-de Murcia J, de Murcia G, Schreiber V (2004)Functional interaction between poly(ADPRibose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2. Mol Cell Biol 24:1595-1607
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1595-1607
-
-
Dantzer, F.1
Giraud-Panis, M.J.2
Jaco, I.3
Ame, J.C.4
Schultz, I.5
Blasco, M.6
Koering, C.E.7
Gilson, E.8
Menissier-De Murcia, J.9
De Murcia, G.10
Schreiber, V.11
-
43
-
-
0037106439
-
Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc
-
Saxena A, Wong LH, Kalitsis P, Earle E, Shaffer LG, Choo KH (2002) Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc. Hum Mol Genet 11:2319-2329
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2319-2329
-
-
Saxena, A.1
Wong, L.H.2
Kalitsis, P.3
Earle, E.4
Shaffer, L.G.5
Choo, K.H.6
-
44
-
-
33749530027
-
Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis i and spermiogenesis
-
Dantzer F, Mark M, Quenet D, Scherthan H, Huber A, Liebe B, Monaco L, Chicheportiche A, Sassone-Corsi P, de Murcia G, and Menissier-de Murcia J (2006) Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis. Proc Natl Acad Sci USA 103:14854-14859
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14854-14859
-
-
Dantzer, F.1
Mark, M.2
Quenet, D.3
Scherthan, H.4
Huber, A.5
Liebe, B.6
Monaco, L.7
Chicheportiche, A.8
Sassone-Corsi, P.9
De Murcia, G.10
Menissier-De Murcia, J.11
-
45
-
-
0036733355
-
The therapeutic potential of poly(ADPribose) polymerase inhibitors
-
Virag L, Szabo C (2002) The therapeutic potential of poly(ADPribose) polymerase inhibitors. Pharmacol Rev 54:375-429
-
(2002)
Pharmacol Rev
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
46
-
-
34548183836
-
PolyADP-ribosylation and cancer
-
Miwa M, Masutani M (2007) PolyADP-ribosylation and cancer. Cancer Sci 98:1528-1535
-
(2007)
Cancer Sci
, vol.98
, pp. 1528-1535
-
-
Miwa, M.1
Masutani, M.2
-
47
-
-
33748929288
-
PARP-2 deficiency affects the survival of CD4?CD8? double-positive thymocytes
-
Yelamos J, Monreal Y, Saenz L, Aguado E, Schreiber V, Mota R, Fuente T, Minguela A, Parrilla P, de Murcia G, Almarza E, Aparicio P, Menissier-de Murcia J (2006) PARP-2 deficiency affects the survival of CD4?CD8? double-positive thymocytes. EMBO J 25:4350-4360
-
(2006)
EMBO J
, vol.25
, pp. 4350-4360
-
-
Yelamos, J.1
Monreal, Y.2
Saenz, L.3
Aguado, E.4
Schreiber, V.5
Mota, R.6
Fuente, T.7
Minguela, A.8
Parrilla, P.9
De Murcia, G.10
Almarza, E.11
Aparicio, P.12
Menissier-De Murcia, J.13
-
48
-
-
78249235926
-
Integrated genomics of susceptibility to alkylator-induced leukemia in mice
-
Cahan P,Graubert TA(2010) Integrated genomics of susceptibility to alkylator-induced leukemia in mice. BMC Genomics 11:638
-
(2010)
BMC Genomics
, vol.11
, pp. 638
-
-
Cahan, P.1
Graubert, T.A.2
-
49
-
-
79957575681
-
PARP-1 and PARP-2: New players in tumour development
-
Yelamos J, Farres J, Llacuna L, Ampurdanes C, Martin-Caballero J (2011) PARP-1 and PARP-2: new players in tumour development. Am J Cancer Res 1:328-346
-
(2011)
Am J Cancer Res
, vol.1
, pp. 328-346
-
-
Yelamos, J.1
Farres, J.2
Llacuna, L.3
Ampurdanes, C.4
Martin-Caballero, J.5
-
50
-
-
14544288305
-
Co-localization of poly(ADPR)polymerase 1 (PARP-1) poly(ADPR)polymerase 2 (PARP-2) and related proteins in rat testis nuclear matrix defined by chemical cross-linking
-
Tramontano F, Di MS, Quesada P (2005)Co-localization of poly(ADPR)polymerase 1 (PARP-1) poly(ADPR)polymerase 2 (PARP-2) and related proteins in rat testis nuclear matrix defined by chemical cross-linking. J Cell Biochem 94:58-66
-
(2005)
J Cell Biochem
, vol.94
, pp. 58-66
-
-
Tramontano, F.1
Di, M.S.2
Quesada, P.3
-
51
-
-
77249164982
-
LMTK2 and PARP-2 gene polymorphism and azoospermia secondary to meiotic arrest
-
Sakugawa N, Miyamoto T, Tsujimura A, Koh E, Miyagawa Y, Sato H, Namiki M, Okuyama A, Sengoku K (2009)LMTK2 and PARP-2 gene polymorphism and azoospermia secondary to meiotic arrest. J Assist Reprod Genet 26:545-552
-
(2009)
J Assist Reprod Genet
, vol.26
, pp. 545-552
-
-
Sakugawa, N.1
Miyamoto, T.2
Tsujimura, A.3
Koh, E.4
Miyagawa, Y.5
Sato, H.6
Namiki, M.7
Okuyama, A.8
Sengoku, K.9
-
52
-
-
36248934231
-
Differential contribution of poly(ADP-ribose)polymerase-1 and-2 (PARP-1 and-2) to the poly(ADP-ribosyl)ation reaction in rat primary spermatocytes. M
-
Tramontano F, Malanga M, Quesada P (2007) Differential contribution of poly(ADP-ribose)polymerase-1 and-2 (PARP-1 and-2) to the poly(ADP-ribosyl)ation reaction in rat primary spermatocytes. M. Mol Hum Reprod 13:821-828
-
(2007)
Mol Hum Reprod
, vol.13
, pp. 821-828
-
-
Tramontano, F.1
Malanga, M.2
Quesada, P.3
-
53
-
-
61349137036
-
Determination of poly(ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation
-
Jha R, Agarwal A, Mahfouz R, Paasch U, Grunewald S, Sabanegh E, Yadav SP, Sharma R (2009)Determination of poly(ADP-ribose) polymerase (PARP) homologues in human ejaculated sperm and its correlation with sperm maturation. Fertil Steril 91:782-790
-
(2009)
Fertil Steril
, vol.91
, pp. 782-790
-
-
Jha, R.1
Agarwal, A.2
Mahfouz, R.3
Paasch, U.4
Grunewald, S.5
Sabanegh, E.6
Yadav, S.P.7
Sharma, R.8
-
55
-
-
79956266186
-
Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis
-
Meyer-Ficca ML, Lonchar JD, Ihara M, Meistrich ML, Austin CA, Meyer RG (2011) Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis. Biol Reprod 84:900-909
-
(2011)
Biol Reprod
, vol.84
, pp. 900-909
-
-
Meyer-Ficca, M.L.1
Lonchar, J.D.2
Ihara, M.3
Meistrich, M.L.4
Austin, C.A.5
Meyer, R.G.6
-
56
-
-
69049091761
-
Parp2 is required for the differentiation of post-meiotic germ cells: Identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2
-
Quenet D, Mark M, Govin J, van Dorsselear A, Schreiber V, Khochbin S, Dantzer F (2009)Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2. Exp Cell Res 315:2824-2834
-
(2009)
Exp Cell Res
, vol.315
, pp. 2824-2834
-
-
Quenet, D.1
Mark, M.2
Govin, J.3
Van Dorsselear, A.4
Schreiber, V.5
Khochbin, S.6
Dantzer, F.7
-
57
-
-
67349218363
-
PARP inhibitors: New partners in the therapy of cancer and inflammatory diseases
-
Peralta-Leal A, Rodriguez-Vargas JM, Aguilar-Quesada R, Rodriguez MI, Linares JL, de Almodovar MR, Oliver FJ (2009)PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases. Free Radic Biol Med 47:13-26
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 13-26
-
-
Peralta-Leal, A.1
Rodriguez-Vargas, J.M.2
Aguilar-Quesada, R.3
Rodriguez, M.I.4
Linares, J.L.5
De Almodovar, M.R.6
Oliver, F.J.7
-
58
-
-
51649101403
-
Poly(ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation
-
Phulwani NK, Kielian T (2008) Poly(ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation. J Neurochem 106:578-590
-
(2008)
J Neurochem
, vol.106
, pp. 578-590
-
-
Phulwani, N.K.1
Kielian, T.2
-
59
-
-
0036897243
-
Antisense oligonucleotides to poly(ADPribose) polymerase-2 ameliorate colitis in interleukin-10-deficient mice
-
Popoff I, Jijon H, Monia B, Tavernini M, Ma M, McKay R, Madsen K (2002) Antisense oligonucleotides to poly(ADPribose) polymerase-2 ameliorate colitis in interleukin-10-deficient mice. J Pharmacol Exp Ther 303:1145-1154
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 1145-1154
-
-
Popoff, I.1
Jijon, H.2
Monia, B.3
Tavernini, M.4
Ma, M.5
McKay, R.6
Madsen, K.7
-
60
-
-
77957931901
-
Genetic ablation of PARP-1 protects against oxazolone-induced contact hypersensitivity by modulating oxidative stress
-
Brunyanszki A, Hegedus C, Szanto M, Erdelyi K, Kovacs K, Schreiber V, Gergely S, Kiss B, Szabo E, Virag L, Bai P (2010) Genetic ablation of PARP-1 protects against oxazolone-induced contact hypersensitivity by modulating oxidative stress. J Invest Dermatol 130:2629-2637
-
(2010)
J Invest Dermatol
, vol.130
, pp. 2629-2637
-
-
Brunyanszki, A.1
Hegedus, C.2
Szanto, M.3
Erdelyi, K.4
Kovacs, K.5
Schreiber, V.6
Gergely, S.7
Kiss, B.8
Szabo, E.9
Virag, L.10
Bai, P.11
-
61
-
-
25144433997
-
Inhibition of poly(ADP-ribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury
-
Mota RA, Sanchez-Bueno F, Saenz L, Hernandez-Espinosa D, Jimeno J, Tornel PL, Martinez-Torrano A, Ramirez P, Parrilla P, Yelamos J (2005)Inhibition of poly(ADP-ribose) polymerase attenuates the severity of acute pancreatitis and associated lung injury. Lab Invest 85:1250-1262
-
(2005)
Lab Invest
, vol.85
, pp. 1250-1262
-
-
Mota, R.A.1
Sanchez-Bueno, F.2
Saenz, L.3
Hernandez-Espinosa, D.4
Jimeno, J.5
Tornel, P.L.6
Martinez-Torrano, A.7
Ramirez, P.8
Parrilla, P.9
Yelamos, J.10
-
62
-
-
79953761260
-
PARP-2 regulates SIRT1 expression and whole-body energy expenditure
-
Bai P, Canto C, Brunyanszki A, Huber A, Szanto M, Cen Y, Yamamoto H, Houten SM, Kiss B, Oudart H, Gergely P, Menissier-de Murcia J, Schreiber V, Sauve AA, Auwerx J (2011) PARP-2 regulates SIRT1 expression and whole-body energy expenditure. Cell Metab 13:450-460
-
(2011)
Cell Metab
, vol.13
, pp. 450-460
-
-
Bai, P.1
Canto, C.2
Brunyanszki, A.3
Huber, A.4
Szanto, M.5
Cen, Y.6
Yamamoto, H.7
Houten, S.M.8
Kiss, B.9
Oudart, H.10
Gergely, P.11
Menissier-De Murcia, J.12
Schreiber, V.13
Sauve, A.A.14
Auwerx, J.15
-
63
-
-
38049129655
-
Poly (ADP-ribose) polymerase-2 controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/peroxisome proliferator-activated receptor-gamma heterodimer
-
Bai P, Houten SM, Huber A, Schreiber V, Watanabe M, Kiss B, de Murcia G, Auwerx J, Menissier-de Murcia J (2007) Poly (ADP-ribose) polymerase-2 controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the retinoid X receptor/peroxisome proliferator-activated receptor-gamma heterodimer. J Biol Chem 282:37738-37746
-
(2007)
J Biol Chem
, vol.282
, pp. 37738-37746
-
-
Bai, P.1
Houten, S.M.2
Huber, A.3
Schreiber, V.4
Watanabe, M.5
Kiss, B.6
De Murcia, G.7
Auwerx, J.8
Menissier-De Murcia, J.9
-
64
-
-
33646946845
-
PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B
-
Maeda Y, Hunter TC, Loudy DE, Dave V, Schreiber V, Whitsett JA (2006) PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B. J Biol Chem 281:9600-9606
-
(2006)
J Biol Chem
, vol.281
, pp. 9600-9606
-
-
Maeda, Y.1
Hunter, T.C.2
Loudy, D.E.3
Dave, V.4
Schreiber, V.5
Whitsett, J.A.6
-
65
-
-
55549119952
-
The histone subcode: Poly(ADPribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha
-
Quenet D, Gasser V, Fouillen L, Cammas F, Sanglier-Cianferani S, Losson R, Dantzer F (2008) The histone subcode: poly(ADPribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha. Faseb J. 22:3853-3865
-
(2008)
Faseb J
, vol.22
, pp. 3853-3865
-
-
Quenet, D.1
Gasser, V.2
Fouillen, L.3
Cammas, F.4
Sanglier-Cianferani, S.5
Losson, R.6
Dantzer, F.7
-
67
-
-
0033198919
-
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
-
D'Amours D, Desnoyers S, D'Silva I, Poirier GG (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 342(Pt 2):249-268
-
(1999)
Biochem J
, vol.342
, Issue.PART 2
, pp. 249-268
-
-
D'Amours, D.1
Desnoyers, S.2
D'Silva, I.3
Poirier, G.G.4
-
68
-
-
61449261908
-
Epigenetics: Poly(ADP-ribosyl)ation of PARP-1 regulates genomic methylation patterns
-
Caiafa P, Guastafierro T, Zampieri M (2009)Epigenetics: poly(ADP-ribosyl)ation of PARP-1 regulates genomic methylation patterns. Faseb J 23:672-678
-
(2009)
Faseb J
, vol.23
, pp. 672-678
-
-
Caiafa, P.1
Guastafierro, T.2
Zampieri, M.3
-
69
-
-
38949198773
-
Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes
-
KrishnakumarR, GambleMJ, FrizzellKM,Berrocal JG,KininisM, KrausWL (2008) Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes. Science 319:819-821
-
(2008)
Science
, vol.319
, pp. 819-821
-
-
Krishnakumar, R.1
Gamble, M.J.2
Frizzell, K.M.3
Berrocal, J.G.4
Kininis, M.5
Kraus, W.L.6
-
70
-
-
0034174670
-
The AgNORs
-
Derenzini M (2000)The AgNORs. Micron 31:117-120
-
(2000)
Micron
, vol.31
, pp. 117-120
-
-
Derenzini, M.1
-
71
-
-
0030462770
-
The peroxisome proliferator-activated receptors: Ligands and activators
-
Forman BM, Chen J, and Evans RM (1996)The peroxisome proliferator- activated receptors: ligands and activators. Ann NY Acad Sci 27:266-275
-
(1996)
Ann NY Acad Sci
, vol.27
, pp. 266-275
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
72
-
-
0030835678
-
The organization, promoter analysis, and expression of the human PPARgamma gene
-
Fajas L, Auboeuf D, Raspe E, Schoonjans K, Lefebvre AM, Saladin R, Najib J, Laville M, Fruchart JC, Deeb S, Vidal-Puig A, Flier J, Briggs MR, Staels B, Vidal H, Auwerx J (1997) The organization, promoter analysis, and expression of the human PPARgamma gene. J Biol Chem 272:18779-18789
-
(1997)
J Biol Chem
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeuf, D.2
Raspe, E.3
Schoonjans, K.4
Lefebvre, A.M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
73
-
-
0027161015
-
PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
-
Bardot O, Aldridge TC, Latruffe N, Green S (1993) PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem Biophys Res Commun 192:37-45
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 37-45
-
-
Bardot, O.1
Aldridge, T.C.2
Latruffe, N.3
Green, S.4
-
74
-
-
0027278522
-
Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
-
Dreyer C, Keller H, Mahfoudi A, Laudet V, Krey G, Wahli W (1993) Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR). Biol Cell 77:67-76
-
(1993)
Biol Cell
, vol.77
, pp. 67-76
-
-
Dreyer, C.1
Keller, H.2
Mahfoudi, A.3
Laudet, V.4
Krey, G.5
Wahli, W.6
-
75
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans RM, Barish GD, Wang YX (2004)PPARs and the complex journey to obesity. Nat Med 10:355-361
-
(2004)
Nat Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
76
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
McKenna NJ, O'Malley BW (2002) Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108:465-474
-
(2002)
Cell
, vol.108
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
77
-
-
33745255099
-
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription
-
Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, Rosenfeld MG (2006) A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science 312:1798-1802
-
(2006)
Science
, vol.312
, pp. 1798-1802
-
-
Ju, B.G.1
Lunyak, V.V.2
Perissi, V.3
Garcia-Bassets, I.4
Rose, D.W.5
Glass, C.K.6
Rosenfeld, M.G.7
-
78
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G, Guarente L (2004)The Sir2 family of protein deacetylases. Annu Rev Biochem 73:417-435
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
79
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
Michan S, Sinclair D (2007) Sirtuins in mammals: insights into their biological function. Biochem J 404:1-13
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
80
-
-
0037207475
-
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis
-
McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M (2003) The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis. Mol Cell Biol 23:38-54
-
(2003)
Mol Cell Biol
, vol.23
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
Lansdorp, P.M.7
Lemieux, M.8
-
81
-
-
25144454432
-
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice
-
Moynihan KA, Grimm AA, Plueger MM, Bernal-Mizrachi E, Ford E, Cras-Meneur C, Permutt MA, Imai S (2005)Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice. Cell Metab 2:105-117
-
(2005)
Cell Metab
, vol.2
, pp. 105-117
-
-
Moynihan, K.A.1
Grimm, A.A.2
Plueger, M.M.3
Bernal-Mizrachi, E.4
Ford, E.5
Cras-Meneur, C.6
Permutt, M.A.7
Imai, S.8
-
82
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NADdependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L (2000)Transcriptional silencing and longevity protein Sir2 is an NADdependent histone deacetylase. Nature 403:795-800
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
83
-
-
83455206803
-
Targeting sirtuin 1 to improve metabolism: All you need is NAD+
-
doi:10.1124/pr.110.003905
-
Canto C, Auwerx J (2012) Targeting sirtuin 1 to improve metabolism: all you need is NAD+ Pharmacol Rev 64:166-187. doi:10.1124/pr.110.003905
-
(2012)
Pharmacol Rev
, vol.64
, pp. 166-187
-
-
Canto, C.1
Auwerx, J.2
-
84
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425:191-196
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
85
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH (2007) Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450:712-716
-
(2007)
Nature
, vol.450
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
Gagne, D.J.6
Jin, L.7
Boss, O.8
Perni, R.B.9
Vu, C.B.10
Bemis, J.E.11
Xie, R.12
Disch, J.S.13
Ng, P.Y.14
Nunes, J.J.15
Lynch, A.V.16
Yang, H.17
Galonek, H.18
Israelian, K.19
Choy, W.20
Iffland, A.21
Lavu, S.22
Medvedik, O.23
Sinclair, D.A.24
Olefsky, J.M.25
Jirousek, M.R.26
Elliott, P.J.27
Westphal, C.H.28
more..
-
86
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD? metabolism and SIRT1 activity
-
Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J (2009)AMPK regulates energy expenditure by modulating NAD? metabolism and SIRT1 activity. Nature 458:1056-1060
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
87
-
-
79953752384
-
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
-
Bai P, Canto C, Oudart H, Brunyanszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J (2011) PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metab 13:461-468
-
(2011)
Cell Metab
, vol.13
, pp. 461-468
-
-
Bai, P.1
Canto, C.2
Oudart, H.3
Brunyanszki, A.4
Cen, Y.5
Thomas, C.6
Yamamoto, H.7
Huber, A.8
Kiss, B.9
Houtkooper, R.H.10
Schoonjans, K.11
Schreiber, V.12
Sauve, A.A.13
Menissier-De Murcia, J.14
Auwerx, J.15
-
88
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P (2005)Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434:113-118
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
89
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME (2004)Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303:2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
90
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W (2001) Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107:137-148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
91
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127:1109-1122
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
92
-
-
78650648938
-
Roles of SIRT1 in the acute and restorative phases following induction of inflammation
-
Zhang Z, Lowry SF, Guarente L, Haimovich B (2010) Roles of SIRT1 in the acute and restorative phases following induction of inflammation. J Biol Chem 285:41391-41401
-
(2010)
J Biol Chem
, vol.285
, pp. 41391-41401
-
-
Zhang, Z.1
Lowry, S.F.2
Guarente, L.3
Haimovich, B.4
-
93
-
-
77349087078
-
SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
-
Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM (2009)SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. Am J Physiol Endocrinol Metab 298:E419-E428
-
(2009)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Yoshizaki, T.1
Schenk, S.2
Imamura, T.3
Babendure, J.L.4
Sonoda, N.5
Bae, E.J.6
Oh, D.Y.7
Lu, M.8
Milne, J.C.9
Westphal, C.10
Bandyopadhyay, G.11
Olefsky, J.M.12
-
94
-
-
33751560439
-
SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents
-
Nayagam VM, Wang X, Tan YC, Poulsen A, Goh KC, Ng T, Wang H, Song HY, Ni B, Entzeroth M, Stunkel W (2006) SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents. J Biomol Screen 11:959-967
-
(2006)
J Biomol Screen
, vol.11
, pp. 959-967
-
-
Nayagam, V.M.1
Wang, X.2
Tan, Y.C.3
Poulsen, A.4
Goh, K.C.5
Ng, T.6
Wang, H.7
Song, H.Y.8
Ni, B.9
Entzeroth, M.10
Stunkel, W.11
-
95
-
-
0028024585
-
The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis
-
Bohinski RJ, Di Lauro R, Whitsett JA (1994) The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol Cell Biol 14:5671-5681
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5671-5681
-
-
Bohinski, R.J.1
Di Lauro, R.2
Whitsett, J.A.3
-
96
-
-
0030057596
-
The T/ebp null mouse: Thyroidspecific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
-
Kimura S, Hara Y, Pineau T, Fernandez-Salguero P, Fox CH, Ward JM, Gonzalez FJ (1996)The T/ebp null mouse: thyroidspecific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev 10:60-69
-
(1996)
Genes Dev
, vol.10
, pp. 60-69
-
-
Kimura, S.1
Hara, Y.2
Pineau, T.3
Fernandez-Salguero, P.4
Fox, C.H.5
Ward, J.M.6
Gonzalez, F.J.7
-
97
-
-
84870669133
-
Impaired fat storage in PARP-2 knockout mice
-
Bai P, Houten SM, Auwerx J, Menisser-de Murcia J, de Murcia GM (2005)Impaired fat storage in PARP-2 knockout mice. Med Sci Monit 11(1):15
-
(2005)
Med Sci Monit
, vol.11
, Issue.1
, pp. 15
-
-
Bai, P.1
Houten, S.M.2
Auwerx, J.3
Menisser-De Murcia, J.4
De Murcia, G.M.5
-
98
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
-
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, hado De OR, Leid M, McBurney MW, and Guarente L (2004)Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 429:771-776
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
De Hado, O.R.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
99
-
-
29144446064
-
Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia
-
Kofler J, Otsuka T, Zhang Z, Noppens R, Grafe MR, Koh DW, Dawson VL, Menisser-de Murcia J, Hurn PD, Traystman RJ (2006) Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia. J Cereb Blood Flow Metab 26:135-141
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 135-141
-
-
Kofler, J.1
Otsuka, T.2
Zhang, Z.3
Noppens, R.4
Grafe, M.R.5
Koh, D.W.6
Dawson, V.L.7
Menisser-De Murcia, J.8
Hurn, P.D.9
Traystman, R.J.10
-
100
-
-
77950921560
-
Contributions of poly(ADP-ribose) polymerase-1 and-2 to nuclear translocation of apoptosis-inducing factor and injury from focal cerebral ischemia
-
Li X, Klaus JA, Zhang J, Xu Z, Kibler KK, Andrabi SA, Rao K, Yang ZJ, Dawson TM, Dawson VL, Koehler RC (2010) Contributions of poly(ADP-ribose) polymerase-1 and-2 to nuclear translocation of apoptosis-inducing factor and injury from focal cerebral ischemia. J Neurochem 113:1012-1022
-
(2010)
J Neurochem
, vol.113
, pp. 1012-1022
-
-
Li, X.1
Klaus, J.A.2
Zhang, J.3
Xu, Z.4
Kibler, K.K.5
Andrabi, S.A.6
Rao, K.7
Yang, Z.J.8
Dawson, T.M.9
Dawson, V.L.10
Koehler, R.C.11
-
101
-
-
0029781555
-
The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice
-
Yen HC, Oberley TD, Vichitbandha S, Ho YS, St Clair DK (1996)The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J Clin Invest 98:1253-1260
-
(1996)
J Clin Invest
, vol.98
, pp. 1253-1260
-
-
Yen, H.C.1
Oberley, T.D.2
Vichitbandha, S.3
Ho, Y.S.4
St Clair, D.K.5
-
102
-
-
72149093510
-
Mitochondria, oxidative metabolism and cell death in stroke
-
Sims NR, Muyderman H (2010) Mitochondria, oxidative metabolism and cell death in stroke. Biochim Biophys Acta 1802:80-91
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 80-91
-
-
Sims, N.R.1
Muyderman, H.2
-
103
-
-
79955528923
-
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection
-
Wen Y, Li W, Poteet EC, Xie L, Tan C, Yan LJ, Ju X, Liu R, Qian H, Marvin MA, Goldberg MS, She H, Mao Z, Simpkins JW, Yang SH (2011) Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. J Biol Chem 286:16504-16515
-
(2011)
J Biol Chem
, vol.286
, pp. 16504-16515
-
-
Wen, Y.1
Li, W.2
Poteet, E.C.3
Xie, L.4
Tan, C.5
Yan, L.J.6
Ju, X.7
Liu, R.8
Qian, H.9
Marvin, M.A.10
Goldberg, M.S.11
She, H.12
Mao, Z.13
Simpkins, J.W.14
Yang, S.H.15
-
104
-
-
79952005057
-
Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia
-
Ye R, Zhang X, Kong X, Han J, Yang Q, Zhang Y, Chen Y, Li P, Liu J, Shi M, Xiong L, and Zhao G Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia. Neuroscience 178:169-180
-
Neuroscience
, vol.178
, pp. 169-180
-
-
Ye, R.1
Zhang, X.2
Kong, X.3
Han, J.4
Yang, Q.5
Zhang, Y.6
Chen, Y.7
Li, P.8
Liu, J.9
Shi, M.10
Xiong, L.11
Zhao, G.12
-
105
-
-
0642280672
-
Dexrazoxane (ICRF-187) protects cardiac myocytes against doxorubicin by preventing damage to mitochondria
-
Hasinoff BB, Schnabl KL, Marusak RA, Patel D, Huebner E (2003) Dexrazoxane (ICRF-187) protects cardiac myocytes against doxorubicin by preventing damage to mitochondria. Cardiovasc Toxicol 3:89-99
-
(2003)
Cardiovasc Toxicol
, vol.3
, pp. 89-99
-
-
Hasinoff, B.B.1
Schnabl, K.L.2
Marusak, R.A.3
Patel, D.4
Huebner, E.5
-
106
-
-
34748877230
-
Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes
-
Tao R, Karliner JS, Simonis U, Zheng J, Zhang J, Honbo N, Alano CC (2007) Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes. Biochem Biophys Res Commun 363:257-262
-
(2007)
Biochem Biophys Res Commun
, vol.363
, pp. 257-262
-
-
Tao, R.1
Karliner, J.S.2
Simonis, U.3
Zheng, J.4
Zhang, J.5
Honbo, N.6
Alano, C.C.7
-
107
-
-
0036171091
-
Melatonin protection against lethal myocyte injury induced by doxorubicin as reflected by effects on mitochondrial membrane potential
-
Xu M, Ashraf M (2002) Melatonin protection against lethal myocyte injury induced by doxorubicin as reflected by effects on mitochondrial membrane potential. J Mol Cell Cardiol 34:75-79
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 75-79
-
-
Xu, M.1
Ashraf, M.2
-
108
-
-
82255172218
-
Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia
-
Panickar KS, Anderson RA (2011) Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia. Int J Mol Sci 12:8181-8207
-
(2011)
Int J Mol Sci
, vol.12
, pp. 8181-8207
-
-
Panickar, K.S.1
Anderson, R.A.2
-
109
-
-
67349234999
-
Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway
-
Danz ED, Skramsted J, Henry N, Bennett JA, Keller RS (2009)Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. Free Radic Biol Med 46:1589-1597
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1589-1597
-
-
Danz, E.D.1
Skramsted, J.2
Henry, N.3
Bennett, J.A.4
Keller, R.S.5
-
110
-
-
54849425547
-
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
-
Feige JN, Lagouge M, Canto C, Strehle A, Houten SM, Milne JC, Lambert PD, Mataki C, Elliott PJ, Auwerx J (2008) Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. Cell Metab 8:347-358
-
(2008)
Cell Metab
, vol.8
, pp. 347-358
-
-
Feige, J.N.1
Lagouge, M.2
Canto, C.3
Strehle, A.4
Houten, S.M.5
Milne, J.C.6
Lambert, P.D.7
Mataki, C.8
Elliott, P.J.9
Auwerx, J.10
-
111
-
-
79953274024
-
Pathways for ischemic cytoprotection: Role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning
-
Morris KC, Lin HW, Thompson JW, Perez-Pinzon MA (2011) Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning. J Cereb Blood Flow Metab 31:1003-1019
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 1003-1019
-
-
Morris, K.C.1
Lin, H.W.2
Thompson, J.W.3
Perez-Pinzon, M.A.4
-
112
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL (2002) Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297:259-263
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
113
-
-
31044446976
-
Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling
-
Ishida J, Yamamoto H, Kido Y, Kamijo K, Murano K, Miyake H, Ohkubo M, Kinoshita T, Warizaya M, Iwashita A, Mihara K, Matsuoka N, Hattori K (2006) Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling. Bioorg Med Chem 14:1378-1390
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 1378-1390
-
-
Ishida, J.1
Yamamoto, H.2
Kido, Y.3
Kamijo, K.4
Murano, K.5
Miyake, H.6
Ohkubo, M.7
Kinoshita, T.8
Warizaya, M.9
Iwashita, A.10
Mihara, K.11
Matsuoka, N.12
Hattori, K.13
-
114
-
-
20044393463
-
Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADPribose) polymerase-1/2 inhibitors
-
Iwashita A, Hattori K, Yamamoto H, Ishida J, Kido Y, Kamijo K, Murano K, Miyake H, Kinoshita T, Warizaya M, Ohkubo M, Matsuoka N, Mutoh S (2005)Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADPribose) polymerase-1/2 inhibitors. FEBS Lett 579:1389-1393
-
(2005)
FEBS Lett
, vol.579
, pp. 1389-1393
-
-
Iwashita, A.1
Hattori, K.2
Yamamoto, H.3
Ishida, J.4
Kido, Y.5
Kamijo, K.6
Murano, K.7
Miyake, H.8
Kinoshita, T.9
Warizaya, M.10
Ohkubo, M.11
Matsuoka, N.12
Mutoh, S.13
-
115
-
-
48149115729
-
On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives
-
Pellicciari R, Camaioni E, Costantino G, Formentini L, Sabbatini P, Venturoni F, Eren G, Bellocchi D, Chiarugi A, Moroni F (2008) On the way to selective PARP-2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives. ChemMedChem 3:914-923
-
(2008)
ChemMedChem
, vol.3
, pp. 914-923
-
-
Pellicciari, R.1
Camaioni, E.2
Costantino, G.3
Formentini, L.4
Sabbatini, P.5
Venturoni, F.6
Eren, G.7
Bellocchi, D.8
Chiarugi, A.9
Moroni, F.10
-
116
-
-
79953790546
-
5-Benzamidoisoquinolin-1-ones and 5-(omega-carboxyalkyl)isoquinolin-1- ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2)
-
Sunderland PT, Woon EC, Dhami A, Bergin AB, Mahon MF, Wood PJ, Jones LA, Tully SR, Lloyd MD, Thompson AS, Javaid H, Martin NM, Threadgill MD (2011) 5-Benzamidoisoquinolin-1-ones and 5-(omega-carboxyalkyl)isoquinolin-1-ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2). J Med Chem 54:2049-2059
-
(2011)
J Med Chem
, vol.54
, pp. 2049-2059
-
-
Sunderland, P.T.1
Woon, E.C.2
Dhami, A.3
Bergin, A.B.4
Mahon, M.F.5
Wood, P.J.6
Jones, L.A.7
Tully, S.R.8
Lloyd, M.D.9
Thompson, A.S.10
Javaid, H.11
Martin, N.M.12
Threadgill, M.D.13
-
117
-
-
70349772693
-
Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage
-
Moroni F, Formentini L, Gerace E, Camaioni E, Pellegrini-Giampietro DE, Chiarugi A, Pellicciari R (2009)Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Br J Pharmacol 157:854-862
-
(2009)
Br J Pharmacol
, vol.157
, pp. 854-862
-
-
Moroni, F.1
Formentini, L.2
Gerace, E.3
Camaioni, E.4
Pellegrini-Giampietro, D.E.5
Chiarugi, A.6
Pellicciari, R.7
-
118
-
-
84870685280
-
-
PARP2 poly(ADP-ribose) polymerase 2 [Ailuropoda melanoleuca] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Ailuropoda melanoleuca] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100483143. Accessed 17 April 2012
-
(2012)
-
-
-
119
-
-
84870673974
-
-
LOC505828 poly[ADP-ribose] polymerase 2-like [Bos taurus] NCBI Pubmed. Accessed 17 April 2012
-
(2012) LOC505828 poly[ADP-ribose] polymerase 2-like [Bos taurus] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/505828. Accessed 17 April 2012
-
(2012)
-
-
-
120
-
-
84870664960
-
-
PARP2 poly(ADP-ribose) polymerase 2 [Callithrix jacchus] NCBI Pubmed.Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Callithrix jacchus] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100388484. Accessed 17 April 2012
-
(2012)
-
-
-
121
-
-
84870666137
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Canis Lupus Familiaris] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Canis lupus familiaris] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/475392. Accessed 17 April 2012
-
(2012)
-
-
-
122
-
-
84870701819
-
-
LOC100720452 poly[ADP-ribose] polymerase 2-like [Cavia porcellus]. NCBI Pubmed. Accessed 17 April 2012
-
(2012) LOC100720452 poly[ADP-ribose] polymerase 2-like [Cavia porcellus]. NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene?term=PARP2%20Cavia%20porcellus. Accessed 17 April 2012
-
(2012)
-
-
-
123
-
-
84870672011
-
-
Parp2 Poly(ADP-ribose) Polymerase Family Member 2 [Cricetulus Griseus]NCBI Pubmed. Accessed 17 April 2012
-
(2012) Parp2 poly(ADP-ribose) polymerase family, member 2 [Cricetulus griseus]NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100753655. Accessed 17 April 2012
-
(2012)
-
-
-
124
-
-
84870654146
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Equus Caballus] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Equus caballus] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100072572. Accessed 17 April 2012
-
(2012)
-
-
-
125
-
-
84870669172
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Loxodonta Africana] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Loxodonta africana] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100661865. Accessed 17 April 2012
-
(2012)
-
-
-
126
-
-
84870696020
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Macaca Mulatta] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Macaca mulatta] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/701955. Accessed 17 April 2012
-
(2012)
-
-
-
127
-
-
84870715022
-
-
LOC100029480 poly[ADP-ribose] polymerase 2-like [Monodelphis domestica] NCBI Pubmed. Accessed 17 April 2012
-
(2012) LOC100029480 poly[ADP-ribose] polymerase 2-like [Monodelphis domestica] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100029480. Accessed 17 April 2012
-
(2012)
-
-
-
128
-
-
84870655248
-
-
Parp2 Poly(ADP-ribose) Polymerase Family Member 2 [Mus Musculus] NCBI Pubmed. Accessed 17 April 2012
-
(2012) Parp2 poly(ADP-ribose) polymerase family, member 2 [Mus musculus] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/11546. Accessed 17 April 2012
-
(2012)
-
-
-
129
-
-
84870686680
-
-
LOC100351185 Poly(ADP-ribose) Polymerase Family Member 2-like [Oryctolagus Cuniculus] NCBI Pubmed. Accessed 17 April 2012
-
(2012) LOC100351185 poly(ADP-ribose) polymerase family, member 2-like [Oryctolagus cuniculus] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100351185. Accessed 17 April 2012
-
(2012)
-
-
-
130
-
-
84870656607
-
-
Parp2 Poly(ADP-ribose) Polymerase 2 [Rattus Norvegicus] NCBI Pubmed. Accessed 17 April 2012
-
(2012) Parp2 poly(ADP-ribose) polymerase 2 [Rattus norvegicus] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/290027. Accessed 17 April 2012
-
(2012)
-
-
-
131
-
-
84870663494
-
-
PARP2 Poly(ADP-ribose) Polymerase 2 [Sus Scrofa] NCBI Pubmed. Accessed 17 April 2012
-
(2012) PARP2 poly(ADP-ribose) polymerase 2 [Sus scrofa] NCBI Pubmed. http://www.ncbi.nlm.nih.gov/gene/100518917. Accessed 17 April 2012
-
(2012)
-
-
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